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Unraveling multimodality of digital health records by comparing mortality trajectories of diagnoses of diseases from over 12 million patients.
Published 2025-01-01“…For example, viral hepatitis, a known predisposing feature of liver cancer in Asia, was observed to initiate in younger Koreans. …”
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High order expression dependencies finely resolve cryptic states and subtypes in single cell data
Published 2025-01-01“…Further, Stator’s fine resolution of liver cancer states reveals expression programmes that predict patient survival. …”
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Rural-Urban Disparity in Premature Cancer Mortality in Young People Aged 15–44 Years in China, 2004–2021
Published 2025-02-01“…More efforts are needed to develop effective early-onset cancer prevention strategies, with particular emphasis on liver cancer and rural areas.…”
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SiameseNet based on multiple instance learning for accurate identification of the histological grade of ICC tumors
Published 2025-02-01“…BackgroundAfter hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer. Timely and accurate identification of ICC histological grade is critical for guiding clinical diagnosis and treatment planning.MethodWe proposed a dual-branch deep neural network (SiameseNet) based on multiple-instance learning and cross-attention mechanisms to address tumor heterogeneity in ICC histological grade prediction. …”
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ENTPD8 overexpression enhances anti-PD-L1 therapy in hepatocellular carcinoma via miR-214-5p inhibition
Published 2025-02-01“…Immunohistochemistry, The Cancer Genome Atlas (TCGA) data, and single-cell expression analysis revealed reduced ENTPD8 levels in liver cancer compared to adjacent tissues, with ENTPD8 primarily expressed in tumor cells within the tumor tissue. …”
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Recent updates of centromere proteins in hepatocellular carcinoma: a review
Published 2025-02-01“…For example, small ribonucleic acid (RNA) can silence CENP expression and prevent the occurrence and development of liver cancer. In recent years, studies of HCC-targeting CENPs have gradually increased but are still relatively novel, requiring further systematic elaboration. …”
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Knowledge of Healthcare Professionals Regarding Hepatitis B in Rania Hospitals
Published 2020-12-01“…It is a potentially life-threatening condition because leads to liver infection, and liver cancer. There is a shortage of research on undergraduate students. …”
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Collagen fibers quantification for liver fibrosis assessment using linear dichroism photoacoustic microscopy
Published 2025-04-01“…Liver fibrosis represents a progressive pathological condition that can culminate in severe hepatic dysfunction, potentially advancing to cirrhosis and liver cancer. The extent of liver fibrosis is intrinsically associated with the quantity of collagen fibers. …”
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Isoacteoside alleviates hepatocellular carcinoma progression by inhibiting PDHB-mediated reprogramming of glucose metabolism
Published 2025-02-01“…PDHB and Isoacteoside could be potential avenues for targeted and combination therapies in liver cancer.…”
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Cancer mortality and sectors of employment: a cohort study in Italy
Published 2025-02-01“…Among women, there was an elevated mortality risk in the cleaning industry for all malignant cancers (HR = 1.15, 95% CI:1.03–1.29), liver cancer (HR = 1.94, 95% CI:1.08–3.48) and cancer of the lympho-hematopoietic tissue (HR = 1.65, 95% CI:1.09–2.50). …”
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