SYNTHESIS AND INFRARED STUDY OF SOME PHENYLPHOSPHONATE, DIPHENYLPHOSPHINATE AND ACETATOPHOSPHONATE NEW ORGANOTIN (IV) DERIVATIVES AND ADDUCTS by MODOU SARR, AMINATA DIASSE-SARR, LIBASSE DIOP

“…The suggested structures, while considering the anionic counterpart, are discrete, dimeric, double and triple metallic components or of infinite chain types, the anion behaving as a monochelating, a bichelating or a bidentate ligand. In OH containing structures, when extra hydrogen bonds are considered, supramolecular architectures may be obtained. …”
Get full text

Synthesis, Characterization and In Vitro Antibacterial Studies of Organotin(IV) Complexes with 2-Hydroxyacetophenone-2-methylphenylthiosemicarbazone (H2dampt) by M. A. Salam, M. A. Affan, Ramkrishna Saha, Fasihuddin B. Ahmad, Norrihan Sam

“…Five new organotin(IV) complexes of 2-hydroxyacetophenone-2-methylphenylthiosemicarbazone [H2dampt, (1)] with formula [RSnCl𝑛−1(dampt)] (where R=Me, 𝑛=2 (2); R=Bu, 𝑛=2 (3); R=Ph, 𝑛=2 (4); R=Me2, 𝑛=1 (5); R=Ph2, 𝑛=1 (6)) have been synthesized by direct reaction of H2dampt (1) with organotin(IV) chloride(s) in absolute methanol. The ligand (1) and its organotin(IV) complexes (2–6) were characterized by CHN analyses, molar conductivity, UV-Vis, FT-IR, 1H, 13C, and 119Sn NMR spectral studies. …”
Get full text

Electrochemically reduced graphene oxide integrated with carboxylated-8-carboxamidoquinoline: A platform for highly sensitive voltammetric detection of Zn(II) ion by screen-printed... by Ling Ling Tan, Nur Syamimi Mohamad, Nurul Izzaty Hassan, Choo Ta Goh

“…A highly sensitive detection of Zn(II) ion via differential pulse voltammetry (DPV) utilizing an environmentally friendly modified screen-printed carbon electrode (SPCE) of electrochemically reduced graphene oxide (ErGO) embedded with carboxylated-8-carboxamidoquinoline (CACQ) as Zn(II) chelating ligand. The green CACQ/ErGO-modified SPCE was characterized by spectroscopy techniques, such as Fourier-transform infrared (FTIR) spectroscopy, Raman spectroscopy, and field-emission scanning electron microscopy with energy dispersive X-ray (FESEM-EDX). …”
Get full text

(2,9-Dimethyl-1,10-phenanthroline)bis[2-(pyridin-2-yl)phenyl]iridium(III) hexafluorophosphate and (2,9-dimethyl-1,10-phenanthroline)bis[5-methyl-2-(pyridin-2-yl)phenyl]iridium(III)... by Trevor J. Gienau, Malachi Clay, William W. Brennessel, Carly R. Reed

“…The Ir—N(phenanthroline) bond lengths of ca. 2.21 Å indicate a greater steric effect of the 2,9-dimethyl-1,10-phenanthroline ligand compared to 1,10-phenanthroline. Both structures show offset parallel intermolecular π–π interactions between the pyridine rings of the phenanthroline ligands, and that of 1 also exhibits similar interactions between the phenyl and pyridine rings of the phenylpyridine ligands.…”
Get full text

Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-κB Signaling by Jiangrui Liu, Liangpan Shi, Wenchang Huang, Zhihua Zheng, Xiaohui Huang, Yibin Su

“…The relative contents of interleukin- (IL-) 1β, tumor necrosis factor- (TNF-) α, IL-6, and the chemokine (C-C motif) ligand 2 (CCL2) in the colon tissues and HHT-treated RAW264.7 cells were detected with the enzyme-linked immunosorbent assay. …”
Get full text

Elucidating Molecular Interactions of Natural Inhibitors with HPV-16 E6 Oncoprotein through Docking Analysis by Satish Kumar, Lingaraja Jena, Sneha Galande, Sangeeta Daf, Kanchan Mohod, Ashok K. Varma

“…Docking analysis, besides helping in silico validation of natural compounds, also helps understand molecular mechanisms of protein-ligand interactions.…”
Get full text

2,4-Dichlorophenoxyacetic Acid Derived Schiff Base and Its Lanthanide(III) Complexes: Synthesis, Characterization, Spectroscopic Studies, and Plant Growth Activity by Ganesh N. Naik, Raghavendra P. Bakale, Aishakhanam H. Pathan, Shashikala G. Ligade, Shreenivas A. Desai, Kalagouda B. Gudasi

“…An enhancement in the plant growth activity of the ligand was observed on complexation and the best activity was observed at 10−6 M concentration.…”
Get full text

Ab Initio Molecular Dynamics Simulations and Vibrational Frequency Calculations of Species in Liquid-Liquid Phase Separated MgSO4 Solution at 543 K by Mengzi Zhou, Xiancai Lu, Xiandong Liu, Yingchun Zhang, Xiaoyu Zhang, Kai Wang

“…Furthermore, bidentate Mg-SO4 ligand is less stable than monodentate ligands at 543 K by applying free energy calculations. …”
Get full text

P2X7 Receptor Activation Induces Reactive Oxygen Species Formation and Cell Death in Murine EOC13 Microglia by Rachael Bartlett, Justin J. Yerbury, Ronald Sluyter

“…The P2X7 purinergic receptor is a ligand-gated cation channel expressed on leukocytes including microglia. …”
Get full text

Extramacrochaetae regulates Notch signaling in the Drosophila eye through non-apoptotic caspase activity by Sudershana Nair, Nicholas E Baker

“…This was associated with caspase-dependent increase in levels of Delta protein, the transmembrane ligand for Notch. Posterior to the morphogenetic furrow, elevated Delta cis-inhibited Notch signaling that was required for R7 specification and cone cell differentiation. …”
Get full text

The Expression of Selected Proapoptotic Molecules in Dermatitis Herpetiformis by Zebrowska Agnieszka, Erkiert-Polguj Anna, Wagrowska-Danilewicz Malgorzata, Danilewicz Marian, Sysa-Jedrzejowska Anna, Anna Cynkier, Waszczykowska Elzbieta

“…Expression of Bax, Fas, and Fas ligand was detected in the keratinocytes in skin biopsies from DH patients. …”
Get full text

The Assessment of Selected Bone and Cartilage Biomarkers in Psoriatic Patients from Poland by Joanna Bartosińska, Anna Michalak-Stoma, Maria Juszkiewicz-Borowiec, Małgorzata Kowal, Grażyna Chodorowska

“…In both groups, the serum concentrations of soluble receptor activator of nuclear factor-κB ligand (sRANKL), cartilage oligomeric matrix protein (COMP), osteoprotegerin (OPG), and interleukin-20 (IL-20) were examined. …”
Get full text

Subtype-specific role for Jagged1 in promoting or inhibiting breast tumor formation by Wen-Cheng Chung, Wei Wang, Lavanya Challagundla, Charles D. Moore, Sean E. Egan, Keli Xu

“…The function of Jagged1, the most highly expressed Notch ligand in the mammary gland, is not well defined. …”
Get full text

Aryl Hydrocarbon Receptor Deficiency in an Exon 3 Deletion Mouse Model Promotes Hematopoietic Stem Cell Proliferation and Impacts Endosteal Niche Cells by Zeenath Unnisa, Kameshwar P. Singh, Ellen C. Henry, Catherine L. Donegan, John A. Bennett, Thomas A. Gasiewicz

“…The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor belonging to the Per-Arnt-Sim (PAS) family of proteins. …”
Get full text

Wharton’s Jelly-Derived Mesenchymal Stem Cells with High Aurora Kinase A Expression Show Improved Proliferation, Migration, and Therapeutic Potential by Sun Jeong Kim, Sang Eon Park, Jang Bin Jeong, Shin Ji Oh, Alee Choi, Yun Hee Kim, Suk-joo Choi, Soo-young Oh, Gyu Ha Ryu, Hong Bae Jeon, Jong Wook Chang

“…Moreover, AURKA from human WJ-MSCs regulated the antiapoptotic effect of skeletal muscle cells by upregulating the chemokine (C motif) ligand (XCL1); this was further confirmed in the mdx mouse model. …”
Get full text

Interaction of toll-like receptors and ACE-2 with different variants of SARS-CoV-2: A computational analysis by Azadeh Zahmatkesh, Elham Salmasi, Reza Gholizadeh

“…Molecular docking and molecular dynamics (MD) simulations were performed to investigate receptor-ligand interactions. Results: The number of motifs recognized by TLR7/8/9 in the Alpha, Delta and Iranian variants was lower than in the wild type (WT). …”
Get full text

Structural comparison of human and Plasmodium proteasome β5 subunits: informing selective inhibitor design for anti-malaria agents by Muhammad Yasir, Jinyoung Park, Eun-Taek Han, Won Sun Park, Jin-Hee Han, Wanjoo Chun

“…This structural arrangement limits the ligand binding pocket's capacity to accommodate only small compounds effectively. …”
Get full text

Structural Analysis of Inhibitor Binding to Enterovirus-D68 3C Protease by Vincent N. Azzolino, Ala M. Shaqra, Akbar Ali, Nese Kurt Yilmaz, Celia A. Schiffer

“…We have determined and analyzed three high-resolution inhibitor-bound crystal structures of EV68-3C protease, which revealed possible sites of resistance mutations, a key structural water molecule conserved during ligand binding, and the conformational flexibility of the catalytic histidine H40. …”
Get full text

Syntheses, Spectral Characterization, and Antimicrobial Studies on the Coordination Compounds of Metal Ions with Schiff Base Containing Both Aliphatic and Aromatic Hydrazide Moieti... by Dinesh Kumar, Silky Chadda, Jyoti Sharma, Parveen Surain

“…They are active against gram-positive bacteria (S. aureus, B. subtilis), gram-negative bacteria (E. coli, P. aeruginosa), and yeast (S. cerevisiae, C. albicans). 1 acts as a dibasic tridentate ONO donor ligand in 2–7 coordinating through its both enolic O and azomethine N atoms. …”
Get full text

Influence of Bath Composition at Acidic pH on Electrodeposition of Nickel-Layered Silicate Nanocomposites for Corrosion Protection by Jeerapan Tientong, Casey R. Thurber, Nandika D’Souza, Adel Mohamed, Teresa D. Golden

“…Citrate was used as a ligand to stabilize nickel (II) ions in the plating solution. …”
Get full text