Coordination Modes of a Schiff Base Derived from Substituted 2-Aminothiazole with Chromium(III), Manganese(II), Iron(II), Cobalt(II), Nickel(II) and Copper(II) Metal Ions: Synthesi... by Ambit Thakar, Krishnakant Joshi, Kishor Pandya, Arvind Pancholi

“…All the complexes were found to be octahedral geometry. The ligand and its complexes have been screened for their antifungal and antibacterial activities against three fungi, i.e. …”
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The Immune Response Is Involved in Atherosclerotic Plaque Calcification: Could the RANKL/RANK/OPG System Be a Marker of Plaque Instability? by Fabrizio Montecucco, Sabine Steffens, François Mach

“…One condition strongly associated with plaque rupture is calcification, a physiopathological process orchestrated by several soluble factors, including the receptor activator of nuclear factor NFκB ligand (RANKL)/receptor activator of nuclear factor NFκB (RANK)/osteoprotegerin (OPG) system. …”
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Toll-like receptor 1/2 activation reduces immunoglobulin free light chain production by multiple myeloma cells in the context of bone marrow stromal cells and fibronectin. by Jahan Abdi, Frank Redegeld

“…This study explored the effect of TLR1/2 ligand (Pam3CSK4) alone or combined with bortezomib (BTZ) on production of FLCs in human myeloma cell lines, L363, OPM-2, U266 and NCI-H929. …”
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A Solution Study of Complex Formation of Some Diamines with Lanthanones by J. J. Vora, D. R. Patel, Asha D. Patel, Kanu Patel, Sangita Sharma, Laxman S. Bhutadiya, Sunil B. Vasava

“…To study the metal ligand equilibrium in aqueous solution, the well known Irving-Rossotti titration method was used. …”
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Molecular Docking Study of Caffeic Acid as Acetylcholinesterase Inhibitor by Stephanus Satria Wira Waskitha, Enade Perdana Istyastono, Florentinus Dika Octa Riswanto

“…Its interactions were stabilized by hydrophobic and pi-anion interactions, in which some of the interactions resemble the same interaction of the native ligand.…”
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Rat Brain Normalization Templates for Robust Regional Analysis of [C]ABP688 Positron Emission Tomography/Computed Tomography by Jeroen Verhaeghe, Leonie Wyffels, Tine Wyckhuys, Sigrid Stroobants, Steven Staelens

“…A methodology to generate rat brain templates for spatial normalization of positron emission tomographic (PET)/computed tomographic (CT) images is described and applied to generate three different templates for imaging of [ 11 C]ABP688, a PET ligand binding to the metabotropic glutamate 5 receptor. …”
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Inhibition of IGF-1R-Dependent PI3K Activation Sensitizes Colon Cancer Cells Specifically to DR5-Mediated Apoptosis But Not to rhTRAIL by Bodvael Pennarun, Jan H. Kleibeuker, Tjitske Oenema, Janet H. Stegehuis, Elisabeth G.E. de Vries, Steven de Jong

“…Background: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) initiates apoptosis in tumor cells upon binding to its cognate agonistic receptors, death receptors 4 and 5 (DR4 and DR5). …”
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Systems Biological Approaches Reveal Non-additive Responses and Multiple Crosstalk Mechanisms between TLR and GPCR Signaling by Jayalakshmi Krishnan, Sangdun Choi

“…A variety of ligands differ in their capacity to bind the receptor, elicit gene expression, and modulate physiological responses. …”
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Disseminated Exfoliative Dermatitis Associated with All-Transretinoic Acid in the Treatment of Acute Promyelocytic Leukemia by Yonal Ipek, Dogru Hulya, Aktan Melih

“…Retinoic acid is a critical ligand in the differentiation pathway of multiple tissues, mediated through binding to an RAR. …”
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Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism by Tsuyoshi Goto, Nobuyuki Takahashi, Shizuka Hirai, Teruo Kawada

“…In this paper, we describe several bioactive terpenoids contained in herbal or dietary plants, which can modulate the activities of ligand-dependent transcription factors, namely, peroxisome proliferator-activated receptors (PPARs). …”
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Peroxisome Proliferator-Activated Receptor Alpha Target Genes by Maryam Rakhshandehroo, Bianca Knoch, Michael Müller, Sander Kersten

“…The peroxisome proliferator-activated receptor alpha (PPARα) is a ligand-activated transcription factor involved in the regulation of a variety of processes, ranging from inflammation and immunity to nutrient metabolism and energy homeostasis. …”
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CARBOXYLATO ADDUCTS AND DERIVATIVES CONTAINING SnR3 (R = Ph, Me) AND SnMe2 RESIDUES: SYNTHESIS, INFRARED AND MÖSSBAUER STUDIES by SEYDOU BASSENE, MOUHAMADOU SEMBENE BOYE, MAMADOU SIDIBE, LIBASSE DIOP

“…The proposed structures are discrete or of infinite chain type, the carboxylate anion behaving as a bridging bidentate, a monodentate, a tetradentate or a monochelating ligand. …”
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Xanthoxyletin blocks the RANK/RANKL signaling pathway to suppress the growth of human pancreatic cancer cells by Zhang Xin, Li Luming, Wu Yan

“…The results revealed a significant (p < 0.05) upregulation of receptor activator of NF-kappaB (RANK), receptor activator of NF-kappaB ligand (RANKL) and osteoprotegerin (OPG) in human pancreatic tissues and cell lines at both transcriptional and translational levels. …”
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Bismuth Schiff base complex and its oxide nanoparticles as photocatalyst for the removal of dyes from water by Behrouz Shaabani, Shadi Soleimaninia

“…Abstract Bismuth oxide and bismuth complexes with organic ligands, particularly Schiff bases, have received much attention due to their non‐toxicity, antibacterial, and photocatalytic properties in removing water and environmental contaminants by oxidative degradation. …”
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Mechanisms of Bone Resorption in Periodontitis by Stefan A. Hienz, Sweta Paliwal, Saso Ivanovski

“…The osteoclast, the principal bone resorptive cell, differentiates from monocyte/macrophage precursors under the regulation of the critical cytokines macrophage colony-stimulating factor, RANK ligand, and osteoprotegerin. TNF-α, IL-1, and PGE2 also promote osteoclast activity, particularly in states of inflammatory osteolysis such as those found in periodontitis. …”
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The Hematopoietic Niche in Myeloproliferative Neoplasms by Annette H. Schmitt-Graeff, Roland Nitschke, Robert Zeiser

“…A complex microenvironment adjacent to the marrow vasculature (vascular niche) and close to the endosteum (endosteal niche) harbors multiple cell types including mesenchymal stromal cells and their derivatives such as CAR cells expressing high levels of chemokines C-X-C motif ligand 12 and early osteoblastic lineage cells, endothelial cells, and megakaryocytes. …”
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Computational illustration of reactions of Cr(CO)3(η6-Naphthalene) complex with C2X2 molecules (X = H, F, Cl) by Seyed Mahdi Mirtaheri, Reza Ghiasi, Mohsen Zeeb, Hossein Anaraki-Ardakani

“…The considered reactions were [2 + 4] Diels–Alder cycloaddition reactions of naphthalene ring of complex with C2X2 molecules and substitution of carbonyl ligand with C2X2 molecule. Energetic aspects of these reactions were explored. …”
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Preparation, Investigation and the Study of the Effect of Mn(II) Complex of Catechol and 2-Aminopyridine on Seed Germination by F. I. El-Moshaty, R. S. El-Zweay, M. M. El-Ajaily, A. M. Jerboa

“…The electronic spectral data display the electronic transitions of the ligands and suggest an octahedral structure for the complex. …”
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PPAR Agonists and Cardiovascular Disease in Diabetes by Anna C. Calkin, Merlin C. Thomas

“…Peroxisome proliferators activated receptors (PPARs) are ligand-activated nuclear transcription factors that play important roles in lipid and glucose homeostasis. …”
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Human Herpesviridae Methods of Natural Killer Cell Evasion by Carl I. Odom, David C. Gaston, James M. Markert, Kevin A. Cassady

“…This paper summarizes the most extensively studied NK cell receptor/ligand pairs and then describes the methods of NK cell evasion used by all eight herpesviruses through these receptors and ligands. …”
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