Myeloid-Related Protein Activity in Rheumatoid Arthritis by Charles J. Malemud

“…Most recently, the MRP-8/MRP-14 complex was shown to be a novel ligand for the toll-like receptors (TLRs) and TLR-4, in particular. …”
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Time-Resolved X-Ray Spectroscopy from the Atomic Orbital Ground State Up by Daniel Jost, Eder G. Lomeli, Ta Tang, Joshua J. Kas, John J. Rehr, Wei-Sheng Lee, Hong-Chen Jiang, Brian Moritz, Thomas P. Devereaux

“…In this paper, we will present simulations of each of these spectroscopies using a time-domain full atomic multiplet, charge-transfer Hamiltonian adapted to study the properties of a generalized cluster model including a central transition-metal ion caged by ligand atoms in a planar geometry. The numerically evaluated trXAS and trRIXS cross sections for representative electron configurations 3d^{9} and 3d^{8} demonstrate the insights that can be obtained from charge-transfer pumping and how this nonequilibrium process affects ground- and excited-state properties. …”
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Infrared Spectroscopic Characterization of Photoluminescent Polymer Nanocomposites by Kyle Gipson, Kathryn Stevens, Phil Brown, John Ballato

“…The ligands were employed to functionalize the surface of Tb3+:LaF3 nanocrystals to aid in dispersing the nanoparticles. …”
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Role of PPARα and Its Agonist in Renal Diseases by Ching-Feng Cheng, Hsi-Hsien Chen, Heng Lin

“…This paper focuses on signaling pathways, ligand selectivity, and physio-pathological roles of PPARα in kidney diseases and the therapeutic utility of PPARα modulators in the treatment of diabetes and inflammation-induced nephropathy. …”
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Design of 3‐aminophenol‐grafted polymer‐modified zinc sulphide nanoparticles as drug delivery system by Milad Abniki, Zahra Azizi, Homayon Ahmad Panahi

“…The ZnS nanoparticle surface was polymerized with allyl glycidyl ether (AGE), and 3‐aminophenol was then deposited as a ligand on nanosorbent. The modified nanosorbent was investigated with Fourier transform infrared spectroscopy and thermogravimetric analysis. …”
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TNIP1 in Autoimmune Diseases: Regulation of Toll-like Receptor Signaling by Rambon Shamilov, Brian J. Aneskievich

“…TNIP1 dysfunction or deficiency may predispose healthy cells to the inflammatory response to otherwise innocuous TLR ligand exposure. The recognition of the anti-inflammatory roles of TNIP1 and improved integrated understanding of its physical and functional association with other signaling pathway proteins may position TNIP1 as a candidate target for the design and/or testing of next-generation anti-inflammatory therapeutics.…”
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Nutrigenomic Functions of PPARs in Obesogenic Environments by Soonkyu Chung, Young Jun Kim, Soo Jin Yang, Yunkyoung Lee, Myoungsook Lee

“…Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors that mediate the effects of several nutrients or drugs through transcriptional regulation of their target genes in obesogenic environments. …”
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Light-Induced Tyrosine Radical Formation from Ruthenium-Tyrosine Complex Anchored to SnO2 Semiconductor by Raed Ghanem

“…A ruthenium(II)-tris(bipyridyl) complex covalently linked to an L-tyrosine ethyl ester through an amide bond was anchored to the surface of nanocrystalline SnO2 via four carboxylic acid groups linked to the bpy ligands. The apparent association constant for the association between ruthenium(II)-tris(bipyridyl) complex and SnO2 is 3.2×106M−1 and a degree of association up to 99% was determined. 450 nm excitation of the complex promotes an electron to a metal-to-ligand charge transfer (MLCT) excited state, from which the electron is injected into SnO2. …”
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Synthesis and Characterization of Trivalent Cerium Complexes of p-tert-Butylcalix[4,6,8]Arenes: Effect of Organic Solvents by Md. Hasan Zahir

“…The Ce3+ ions in the complexes are proved to combine with the ligand phenolic groups, oxygen atoms of DMF molecules, and/or OH− ions.…”
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Synthesis, Characterization and Antibacterial Activity of Mn(II), Co(II), Ni(II) and Cu(II) Complexes of 4-Carboxaldehyde Phenylhydrazone- 1-phenyl-3-methyl-2-pyrazolin-5-one by R. N. Pandya, A. K. Rana, H. R. Dabhi, R. B. Patel, D. K. Bhoi, M. B. Patel, K. S. Solanki, R. K. Rai, A. D. Raj

“…4-Carboxaldehyde-1-phenyl-3-methyl-2-pyrazolin-5-one condensed with phenylhydrazine to form ligand (HL). These metal complexes are of type [ML2 (H2O)2] (M = Mn, Co, Ni and Cu). …”
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Theoretical Study of the Chemical Properties and the Reaction Pathway of Decarbonylative Alkylative Esterification of Styrenes with Aliphatic Aldehydes by Meysam Madahi, Dadkhoda Ghazanfari, Sayed Ali Ahmadi

“…The decarbonylative alkylative esterification was restricted exclusively to cobalt catalysts. The step of ligand exchange was the rate-determining step for this reaction.…”
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The Suzuki−Miyaura Cross-Coupling−Claisen Rearrangement−Cross-Metathesis Approach to Prenylated Isoflavones by George, Kwesiga, Julia, Greese, Alexandra, Kelling, Eric, Sperlich, Bernd, Schmidt

“…Using Pd(dba)2 as a precatalyst and tricyclohexylphosphine as an activating ligand, reliable cross-coupling conditions were identified. …”
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SSL5-AnxA5 Fusion Protein Constructed Based on Human Atherosclerotic Plaque scRNA-Seq Data Preventing the Binding of Apoptotic Endothelial Cells, Platelets, and Inflammatory Cells by Yifei Zhao, Xingyu He, Teng Hu, Tianli Xia, Fangyang Huang, Changming Li, Yiming Li, Fei Chen, Mao Chen, Jun Ma, Yong Peng

“…Through single-cell sequencing analysis (scRNA-seq) of plaques from SAP and ACS patients, we identified significant changes in the annexin V and P-selectin glycoprotein ligand 1 pathways. Staphylococcal superantigen-like 5 (SSL5) is an optimal antagonist P-selectin glycoprotein ligand 1 (PSGL1), while annexin V (AnxA5) can precisely detect dead cells in vivo. …”
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Synthesis, Characterization, and Cytotoxic Activity of New Lanthanum(III) Complexes of Bis-Coumarins

“…<p>Complexes of lanthanum(III) with bis-coumarins: 3,<mml:math alttext="$3'$"> <mml:msup> <mml:mn>3</mml:mn> <mml:mo>&#x2032;</mml:mo> </mml:msup> </mml:math>-benzylidene-bis(4-hydroxy-2H-1-benzopyran-2-one) (<mml:math alttext="$chem{H_{2}}$"> <mml:msub> <mml:mtext>H</mml:mtext> <mml:mn>2</mml:mn> </mml:msub> </mml:math>L1) and bis(4-hydroxy-2-oxo-2H-chromen-3-yl)-(1H-pyrazol-3-yl)-methane (<mml:math alttext="$chem{H_{2}}$"> <mml:msub> <mml:mtext>H</mml:mtext> <mml:mn>2</mml:mn> </mml:msub> </mml:math>L2) were synthesized by reaction of lanthanum(III) salt and the ligands, in amounts equal to metal : ligand molar ratio of <mml:math alttext="$1 : 2$"> <mml:mn>1</mml:mn><mml:mo>:</mml:mo><mml:mn>2</mml:mn> </mml:math>. …”
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Increased serum soluble PD-l1 levels in patients with advanced stages of chronic kidney disease by Ayaka Hayashi, Ayaka Hayashi, Hiroto Ishihara, Mayuko Kawabe, Kazuhiko Kato, Kazuhiko Kato, Akio Nakashima, Akio Nakashima, Izumi Yamamoto, Teppei Sakano, Teppei Sakano, Hiroe Kobashi, Makoto Morita, Makoto Morita, Takashi Yokoo, Mitsuyoshi Urashima

“…BackgroundProgramed death-ligand 1 (PD-L1) is overexpressed on renal tubular and vascular epithelial cells in inflammatory kidney diseases as well as on aged kidney podocytes, contributing to chronic kidney disease (CKD) progression. …”
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Natural Product Identification and Molecular Docking Studies of Leishmania Major Pteridine Reductase Inhibitors by Moses N. Arthur, George Hanson, Emmanuel Broni, Patrick O. Sakyi, Henrietta Mensah-Brown, Whelton A. Miller, Samuel K. Kwofie

“…A 100 ns MD combined with molecular mechanics Poisson–Boltzmann surface area (MM/PBSA) calculations confirmed the robust binding interactions and provided insights into the dynamics and stability of the protein–ligand complexes.…”
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Therapeutic Implications of Targeting Energy Metabolism in Breast Cancer by Meena K. Sakharkar, Babita Shashni, Karun Sharma, Sarinder K. Dhillon, Prabhakar R. Ranjekar, Kishore R. Sakharkar

“…PPARs are ligand activated transcription factors. PPARγ agonists have been reported as a new and potentially efficacious treatment of inflammation, diabetes, obesity, cancer, AD, and schizophrenia. …”
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PPARγ as a Novel Therapeutic Target in Lung Cancer by Aravind T. Reddy, Sowmya P. Lakshmi, Raju C. Reddy

“…Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. …”
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Structure-based insights into fluorogenic RNA aptamers by Song Qianqian, Tai Xiaoqing, Ren Qianyu, Ren Aiming

“…This review summarizes the structure-based investigations of fluorogenic RNA aptamers, with a focus on their overall folds, ligand-binding pockets and fluorescence activation mechanisms. …”
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Influence of TiO2 Nanocrystals Fabricating Dye-Sensitized Solar Cell on the Absorption Spectra of N719 Sensitizer by Puhong Wen, Yinfeng Han, Weixing Zhao

“…In particular, the low-energy metal-to-ligand charge-transfer transitions (MLCT) band in the visible absorption spectra of N719 is strongly affected, and locations of these MLCT bands revealed larger differences. …”
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