QSAR modelling and docking analysis of some thiazole analogues as alfa-glucosidase inhibitors by Muhammad Tukur Ibrahim, Adamu Uzairu, Gideon Adamu Shallangwa, Sani Uba

“…Based on its statistical fitness, the first model was selected and chosen as the studied model and assessed with R2 = 0.906134, R2 adj = 0.89049, Q2cv = 0.86149 and R2 pred = 0.82581. The ligand with the highest binding energy of -11.0 kcal/mol among the other ligands was ligand 13 as indicated by the molecular docking. …”
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Novel Gallium(III), Germanium(IV), and Hafnium(IV) Folate Complexes and Their Spectroscopic, Thermal Decomposition, Morphological, and Biological Characteristics by Abeer A. El-Habeeb

“…These complexes were synthesized through the chemical interactions in neutralized media between the folic acid drug ligand (FAH2) with GaCl3, GeCl4, and HfCl4 metal salts at 1 : 2 (metal : ligand) molar ratio. …”
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Synthesis, Characterization and Antibacterial Studies of Some Transition Metal Complexes of a Schiff Base Derived from 2-(Aminomethyl)- benzimidazole and Thiophene-2-carbaxaldehyde by Pragathi Jogi, K. Mounika, M. Padmaja, Lakshmi M., C. Gyanakumari

“…It has been found that all the complexes are antimicrobially active and show higher activity than ligand.…”
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Coordination Behavior of Ni2+, Cu2+, and Zn2+ in Tetrahedral 1-Methylimidazole Complexes: A DFT/CSD Study by Samuel Tetteh

“…The interaction between metal d-orbitals (donor) and ligand orbitals (acceptor) was also explored using second-order perturbation of the Fock matrix. …”
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Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway by Yunfei Mu, Shijia Hu, Xiangyang Liu, Xin Tang, Jiayi Lin, Hongjun Shi

“…By transiently blocking the heartbeat of E9.5 mouse embryos, we found that Notch activation in the arterial endothelium was dependent on its ligand Dll4, whereas the reduced expression of Dll4 in the endocardium led to a ligand-depleted field, enabling Notch to be specifically activated in AVC and OFT by regional increased shear stress. …”
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Pembrolizumab plus Pemetrexed and Platinum in Metastatic Non-Squamous Non-Small Cell Lung Cancer: A Real-Life Study at a Portuguese Centre by Maria João Santos, Filipa Ferro, Andrea Machado, Ana Sofia Vilariça, Direndra Hasmucrai, Paula Alves

“… First-line therapy for metastatic non-small-cell lung cancer without targetable mutations is platinum-based chemotherapy plus pembrolizumab if programmed death ligand 1 is < 50%. The aim of this real-life retrospective study is to assess the efficacy and safety of this therapy. …”
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Kinetics and Mechanism of the Reaction between Chromium(III) and 2,3-Dihydroxybenzoic Acid in Weak Acidic Aqueous Solutions by Athinoula L. Petrou, Vladimiros Thoma, Konstantinos Tampouris

“…The reaction between chromium(III) and 2,3-dihydroxybenzoic acid (2,3-DHBA) takes place in at least three stages, involving various intermediates. The ligand (2,3-DHBA)-to-chromium(III) ratio in the final product of the reaction is 1 : 1. …”
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Synthesis, Characterization, and Anticancer Activity of New Metal Complexes Derived from 2-Hydroxy-3-(hydroxyimino)-4-oxopentan-2-ylidene)benzohydrazide by Abdou Saad El-Tabl, Moshira Mohamed Abd El-Waheed, Mohammed Ahmed Wahba, Nahla Abd El-Halim Abou El-Fadl

“…Novel metal(II) complexes derived from 2-hydroxy-N′-((Z)-3-(hydroxyimino)-4-oxopentan-2-ylidene)benzohydrazide ligand (H2L) were synthesized and characterized by elemental and thermal analyses (DTA and TGA), IR, UV-VIS, 1H-NMR, ESR and mass spectroscopy, magnetic susceptibilities, and conductivities measurements. …”
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NEW MX2 AND M’Cl3 (M = Cu, Zn; M’= Y, Dy, Pr; X = Cl, Br) MALEATO COMPLEXES AND TETRAPHENYLANTIMONY FORMIATE ADDUCT: SYNTHESIS AND INFRARED STUDY by DAME SEYE, CHEIKH ABDOUL KHADIR DIOP, ASSANE TOURE, LIBASSE DIOP

“…The maleate anion behaves as a bidentate, a monochelating, a bichelating or a tetradentate ligand while the formiate anion behaves as a monodentate ligand. …”
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Photoinduced energy-transfer in covalently and non-covalently linked supramolecular arrays of metal polypyridyl complexes by Michael D. Ward

“…In the first type the components (metal polypyridyl complexes) are covalently linked by using the bridging ligand 2,2′:3′,2″:6″,2′″-quaterpyridine, which has two inequivalent bipyridyl chelating sites in close proximity. …”
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Analysis of Progress and Challenges of EGFR-Targeted Molecular Imaging in Cancer With a Focus on Affibody Molecules by Weizhi Chen MD, Baozhong Shen MD, PhD, Xilin Sun PhD

“…Each substrate or probe, whether it is an endogenous ligand, antibody, peptide, or small molecule labeled with fluorochrome or radionuclide, has unique advantages and limitations. …”
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Computational Studies of 4-Formylpyridinethiosemicarbazone and Structural and Biological Studies of Its Ni(II) and Cu(II) Complexes by Mydhili P. Sripathi, Sireesha Berely, Chittireddy Venkata Ramana Reddy

“…These complexes also promote hydrolytic cleavage of plasmid pBR322. The ligand (H4FPT) and its complexes showed moderate-to-good activity against Gram-positive and Gram-negative bacterial strains. …”
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Determination of Trace Amount of Cadmium by Atomic Absorption Spectrometry in Table Salt after Solid Phase Preconcentration Using Octadecyl Silica Membrane Disk Modified by a New D... by Mahmood Payehghadr, Sousan Esmaeilpour, Mohammad Kazem Rofouei, Laleh Adlnasab

“…The method is based on the adsorption of Cd on 1,2-bis(pyridin-2-ylmethylene) hydrazine as Schiff base ligand on silica-C18 disk. The effects of several factors such as type and concentration of the eluent, pH of sample solution, amount of ligand, and breakthrough volume have been optimized based on one variable at a time. …”
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Synthesis and Crystal Structure of the Bioinorganic Complex [Sb(Hedta)]·2H2O by Di Li, Guo-Qing Zhong

“…The Sb(III) ion is five-coordinated by two amido N atoms and three carboxyl O atoms from a single Hedta3− ligand, forming a distorted trigonal bipyramid geometry. …”
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Recent Advances in Biosensors Using Enzyme-Stabilized Gold Nanoclusters by Myeong-Jun Lee, Jeong-Hyeop Shin, Seung-Hun Jung, Byung-Keun Oh

“…As a result, the properties of AuNCs and their formation are determined by the ligand, so the selection of the ligand is important. …”
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Revealing the electron driven mechanism in metal catalyzed Kumada cross coupling reaction by Noriyuki Takai, Takuro Tsutsumi, Kenichiro Saita, Tetsuya Taketsugu, Takao Tsuneda

“…Abstract The electron motion mechanism of the metal-catalyzed Kumada cross-coupling reaction, which synthesizes biphenyl from chlorobenzene and phenylmagnesium chloride (a Grignard reagent) using a palladium (Pd) complex with an auxiliary phosphine ligand, is elucidated. This analysis is grounded in reactive orbital energy theory (ROET), enabling the examination of electron motions in comprehensive chemical reactions. …”
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Synthesis, Characterization, and Catalytic Activity of Pd(II) Salen-Functionalized Mesoporous Silica by Rotcharin Sawisai, Ratchaneekorn Wanchanthuek, Widchaya Radchatawedchakoon, Uthai Sakee

“…Salen ligand synthesized from 2-hydroxybenzaldehyde and 2-hydroxy-1-naphthaldehyde was used as a palladium chelating ligand for the immobilization of the catalytic site. …”
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New Boric Acid Derivative with Some of Its Complexes and Study the Biological and Anticancer Activity by Alaa Abdullah Majeed, Asmaa Mohammed Noori

“… A new ligand (5-(2-benzamido-N-methylacetamido)-4-((3,4,5-trimethoxycyclohexa-1,3-dien-1-yl) methyl) pyrimidine-2-yl) amino)boric acid was synthesized by the reaction of trimethoprim amide derivative with boric acid, as well as its metal complexes with Co (II), Ni (II), and Pt (IV). …”
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Synthesis and Characterization of Oxidovanadium(IV) Complexes of 2-((E)-(6-Fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol and Their Antimicrobial, Antioxidant, and DNA-Bin... by K. Savithri, H. D. Revanasiddappa

“…Two novel oxidovanadium(IV) complexes with a new bidentate (O- and N-) imine-based ligand 2-((E)-(6-fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol (HL) were synthesized under in situ experimental condition where VOSO4 acts as a kinetic template in the ratio 2 : 1 (L : M) and mixed ligand complex using 1,10-phenanthroline (phen) in 1 : 1 : 1 (L : M : phen) ratio. …”
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Exploration of Potent Human α-Glucosidase Inhibitors Using In Silico Approaches: Molecular Docking, DFT, Molecular Dynamics Simulations, and MMPBSA by Jyoti Bashyal, Bimal Kumar Raut, Siddha Raj Upadhyaya, Kabita Sharma, Niranjan Parajuli

“…The subsequent analysis of MMPBSA indicating a higher binding free energy of these compounds compared to reference ligand, acarbose further strengthened the validity of these findings. …”
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