Biological Evaluation of Platinum(II) Sulfonamido Complexes: Synthesis, Characterization, Cytotoxicity, and Biological Imaging by Charini Maladeniya, Taniya Darshani, Sameera R. Samarakoon, Frank R. Fronczek, W. M. C. Sameera, Inoka C. Perera, Theshini Perera

“…Time-dependent density functional theory calculations suggested that the excitation of L1 show quin-unit-based π⟶π∗ excitations (i.e., ligand-centered charge transfer, LC), while C1 shows the metal-ligand-to-ligand charge-transfer (MLLCT) character. …”
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Synthesis, Spectral Characterization, and Thermal and Cytotoxicity Studies of Cr(III), Ru(III), Mn(II), Co(II), Ni(II), Cu(II), and Zn(II) Complexes of Schiff Base Derived from 5-H... by Amani S. Alturiqi, Abdel-Nasser M. A. Alaghaz, Reda A. Ammar, Mohamed E. Zayed

“…The measurements of magnetic susceptibility, ligand field parameter, and reflectance spectra suggested an octahedral geometry for the complexes. …”
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Synthesis, Characterization, Semiempirical and Biological Activities of Organotin(IV) Carboxylates with 4-Piperidinecarboxylic Acid by Shabbir Hussain, Saqib Ali, Saira Shahzadi, Saroj K. Sharma, Kushal Qanungo, Muhammad Shahid

“…The FT-IR data indicate the bidentate chelating mode of the carboxylate ligand which is also confirmed by semiempirical study. …”
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Binding Mode Investigation of Polyphenols from Scrophularia Targeting Human Aldose Reductase Using Molecular Docking and Molecular Dynamics Simulations by Abinaya Manivannan, Prabhakaran Soundararajan, Yoo Gyeong Park, Sugunadevi Sakkiah, Byoung Ryong Jeong

“…Moreover, the molecular dynamics simulation of ALR2-acacetin complex was validated for the stability of ligand binding and the refined complex was used for generation of receptor-ligand pharmacophore model. …”
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The Role of System-Specific Molecular Chaperones in the Maturation of Molybdoenzymes in Bacteria by Meina Neumann, Silke Leimkühler

“…Enzymes of the xanthine oxidase family are characterized to contain an equatorial sulfur ligand at the molybdenum center of Moco. This sulfur ligand is inserted into Moco while bound to the XdhC-like protein and before its insertion into the target enzyme. …”
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Synthesis Characterization and Biological Investigations on Metal Complexes of 2-[(8-Hydroxy-1-quinolin-5-yl) methyl]-1H-isoindole-1, 3 (2H) dione by M. R. Solanki, G. D. Acharya, M. V. Hathi

“…Coordination of the ligand atom to the metal ion was deduced by IR and reflecting spectral data. …”
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A Mathematical Model of Receptor-Mediated Apoptosis: Dying to Know Why FasL is a Trimer by Ronald Lai, Trachette L. Jackson

“…Analysis andsimulation suggest that if the death signal is to be successful at low-receptor, high-ligand concentration, Fas trimerization is unlikely tobe the driving force in the signal propagation. …”
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Selective Modulators of PPAR-γ Activity: Molecular Aspects Related to Obesity and Side-Effects by Fang Zhang, Brian E. Lavan, Francine M. Gregoire

“…The identification of putative natural and synthetic ligands and activators of PPAR-γ has helped to unravel the molecular basis of its function, including molecular details regarding ligand binding, conformational changes of the receptor, and cofactor binding, leading to the emergence of the concept of selective PPAR-γ modulators (SPPARγMs). …”
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RNA folding kinetics control riboswitch sensitivity in vivo by David Z. Bushhouse, Jiayu Fu, Julius B. Lucks

“…Abstract Riboswitches are ligand-responsive gene-regulatory RNA elements that perform key roles in maintaining cellular homeostasis. …”
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Magnetic Property and Therapeutic Effect of a New Co(II) Complex on Liver Cancer by Regulating the Expression of miRNA31 by Zhenshan Guo, Jun Zhen, Zhoujia Yao, Yemeng Wang, Chenlu Jin

“…Employing the flexible hexacarboxylate ligand of 1,3,5-triazine-2,4,6-triamine hexaacetic acid (H6TTHA) to assemble with Co(NO3)2·6H2O, we have acquired a novel coordination compound, i.e., [Co2(H2TTHA)(H2O)]n·6n(H2O) (1). …”
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New Copper and Oxomolybdate Robson-Type Polynuclear Macrocyclic Complexes: Structure, Spectroscopy, and Electrochemical Properties by Marcelo Carpes Nunes, Marcos Antonio Ribeiro, Fábio Souza Nunes

“…The polynuclear complexes [Mo3O8(tidf)]·dmso·2H2O (1) and [{Cu2(tidf)}2(μ-Mo8O24)] (2) (tidf2− is a symmetrical tetraiminodiphenolate Robson-type macrocyclic ligand) were prepared from equimolar combinations of [Mg2(tidf)](NO3)2·4H2O, [MoO2Cl2(dmso)2] (for 1) and complex 1 and Cu(ClO4)2·4H2O (for 2) in acetonitrile. …”
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Tin(IV) Complexes of Schiff Base Derived from Amino Acid: Synthesis and Characteristic Spectral Studies by Robina Aman, Garima Matela

“…The binding site of the ligand was identified by IR spectroscopic measurement. …”
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Review of the Structural and Dynamic Mechanisms of PPARγ Partial Agonism by Alice J. Kroker, John B. Bruning

“…PPARγ (peroxisome proliferator activated receptor γ) is a ligand activated transcription factor of the nuclear receptor superfamily that controls the expression of a variety of genes involved in fatty acid metabolism, adipogenesis, and insulin sensitivity. …”
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Micelle Mediated Trace Level Sulfide Quantification through Cloud Point Extraction by Samrat Devaramani, Pandurangappa Malingappa

“…The reaction variables like metal ion, ligand, surfactant concentration, and medium pH on the cloud point extraction of the metal-ligand complex have been optimized. …”
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Targeting SLC4A4: A Novel Approach in Colorectal Cancer Drug Repurposing by Krunal Pawar, Pramodkumar P. Gupta, Pooran Singh Solanki, Ravi Ranjan Kumar Niraj, Shanker L. Kothari

“…Molecular dynamics simulations revealed strong protein–ligand interactions with consistent RMSD (~0.25 nm), RMSF (~0.5 nm), compact Rg (4.0–3.9 nm), and stable SASA profiles, indicating that the SLC4A4 structure remains stable upon ligand binding. …”
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Synthesis, Characterization, Cyclic Voltammetry, and Biological Studies of Co(II), Ni(II), and Cu(II) Complexes of a Tridentate Schiff Base, 1-((E)-(2-Mercaptophenylimino) Methyl)... by Maurice Kuate, Mariam Asseng Conde, Evans Ngandung Mainsah, Awawou G. Paboudam, Francis Merlin M. Tchieno, Kevin I. Y. Ketchemen, Ignas Tonle Kenfack, Peter T. Ndifon

“…Antioxidant studies reveal that the ligand and its Cu(II) complex are more potent than Co(II) and Ni(II) complexes to eliminate free radicals.…”
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Synthesis and Spectroscopic and Biological Activities of Zn(II) Porphyrin with Oxygen Donors by Gauri Devi Bajju, Sujata Kundan, Madhulika Bhagat, Deepmala Gupta, Ashu Kapahi, Geeta Devi

“…Results of investigation of the physicochemical properties of zinc complexes containing substituted phenols as axial ligand having general formula [X-Zn-t(p-CH3) PP] [where X = different phenolates as axial ligand] in impurity-free organic solvent are presented. …”
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The comparison of biodistribution of glutathione PEGylated nanoliposomal doxorubicin formulations prepared by pre‐insertion and post‐insertion methods for brain delivery in normal... by Amin Mehrabian, Saba Dadpour, Mohammad Mashreghi, Javad Zarqi, Anis Askarizadeh, Ali Badiee, Leila Arabi, Seyedeh Alia Moosavian, Mahmoud Reza Jaafari

“…In addition, PEGylated nanoliposomal doxorubicin connected to the spacer‐GSH targeting ligand (GSGGCE) and the PEG3400 was conducted using post‐insertion method. …”
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Anti-atherosclerosis potential activity from Alphitobius diaperinus: a molecular docking study on NLRP3 receptor by Firdaus Hasibuan, Erfan Andrianto Aritonang

“…The target receptor used was NLRP3, with β-sitosterol and campesterol as the test ligands, and simvastatin as the control ligand. The results showed that the binding affinity energies of β-sitosterol and campesterol were more negative than simvastatin, with values of -9.3, -9.3, and -8.6 kcal/mol, respectively. …”
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Computational studies of some benzothiazinone-pepirazine derivatives and lipase b inhibitor for mycobacterium tuberculosis by Yakubu Ya'u Muhammad, Adamu Uzairu

“…Ligand 6 being among the ligands with the highest binding affinity (-10.5 k/mole) was found to be more potent than other compounds. …”
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