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281
Synthesis, Spectroscopic Characterization, and Biological Evaluation Studies of 5-Bromo-3-(((hydroxy-2-methylquinolin-7-yl)methylene)hydrazono)indolin-2-one and Its Metal (II) Comp...
Published 2014-01-01“…In addition, the free ligand along with its complexes has been studied for their antioxidant activity.…”
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282
Synthesis of CuO Nanoparticles from Copper(II) Schiff Base Complex: Evaluation via Thermal Decomposition
Published 2025-01-01“…This newly synthesized symmetric Schiff base served as the ligand for the Cu(II) metal ion complex. The ligand and its complex were characterized using several spectroscopic methods, including FTIR, UV-vis, 1H-NMR, 13C-NMR, CHNS, and AAS, along with TGA, molar conductivity and magnetic susceptibility measurements. …”
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283
Glucocorticoid receptor: translocation from the cytoplasm to the nuclei, chromatin and intranuclear chaperone cycles
Published 2015-07-01“…Glucocorticoid receptor (GR) is a ligand-dependent transcription factor, involved in the regulation of hundreds of genes. …”
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284
Cytokine-armed oncolytic herpes simplex viruses: a game-changer in cancer immunotherapy?
Published 2024-05-01“…In this review, we highlight preliminary data with several cytokines and chemokines, including GM-CSF, interleukin 12, FMS-like tyrosine kinase 3 ligand, tumor necrosis factor α, interleukin 2, interleukin 15, interleukin 18, chemokine (C-C motif) ligand 2, chemokine (C-C motif) ligand 5, chemokine (C-X-C motif) ligand 4, or their combinations, and show how these payloads can further enhance the antitumor immunity of oHSV. …”
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285
Bioinorganic Relevance of Some Cobalt(II) Complexes with Thiophene-2-glyoxal Derived Schiff Bases
Published 2009-01-01“…IR spectra manifest the coordination of the ligand to the metal ion through the carbonyl oxygen, azomethine nitrogen and thienyl sulphur atoms. …”
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286
Synthesis and Crystalline Structure of Zinc Complexes with Antihypertensive Drug Lisinopril
Published 2018-01-01“…The structural investigation of Zn2+ complexes with the ligand lisinopril (LIS), an inhibitor of angiotensin-converting enzyme (ACE), was performed. …”
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287
Synthesis Characterization and Antimicrobial Activity Studies of Some Transition Metal Complexes Derived from 3-Chloro-N′-[(1E)-(2-hydroxy phenyl)methylene]-6-methoxy-1-benzothioph...
Published 2013-01-01“…The Schiff base behaves as tridentate ONO donor ligand and forms the complexes of the type ML2 (metal-ligand) stoichiometry for Cu(II), Co(II), Ni(II), and Mn(II) complexes and ML stoichiometry for Zn(II), Hg(II), and Fe(III) complexes. …”
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288
Synthesis, Structure, and Anticancerous Properties of Silver Complexes
Published 2013-01-01“…Mixed ligand complexes of Ag(I) metal derived from L-lysine and thiouracil with 2,2′-bipyridyl; 2-aminopyridine with thiouracil have been synthesized. …”
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289
Synthesis, Spectroscopy, Thermal Analysis, Electrochemistry and Superoxide Scavenging Activity of a New Bimetallic Copper(II) Complex
Published 2013-01-01“…A new bimetallic copper(II) complex has been synthesized with ligand obtained by the condensation of salicylaldehyde and the amine derived from reduction of nitration product of benzil. …”
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290
Scaffold-enabled high-resolution cryo-EM structure determination of RNA
Published 2025-01-01“…In the case of the TPP riboswitch aptamer domain, the scaffolding approach allowed visualization of the riboswitch ligand binding pocket at 2.5 Å resolution. We also determined the structure of the ligand-free apo state and observe that the aptamer domain of the riboswitch adopts an open Y-shaped conformation in the absence of ligand. …”
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291
Selective union of ATP vs ADP to an amino/amide macrocycle and its Cu2+ complexes: potentiometric, spectrophotometric and theoretical approximations
Published 2022-08-01“… The protonation equilibria of a new amine/amide type macrocycle and its complexation with Cu(II) in solution have been studied by potentiometry and UV-Visible Spectrophotometry. The ligand shows four protonation constants and one unusual deprotonation constant. …”
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292
Synthesis, Characterization, and Antibacterial Activities of 1H-Imidazo [5, 6-f] [1,10] Phenanthroline-2(3H)-Thione and Its Ni(II) and Cu(II) Complexes
Published 2019-01-01“…Both Cu(II) and Ni(II) complexes exhibit higher antibacterial activities than the free ligand.…”
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293
Preparation and Characterization of a Novel Terbium Complex Coordinated with 10-Undecenoic Acid for UV-Cured Coatings
Published 2020-01-01“…Furthermore, the luminescence properties of complexes with different ratios of Tb3+ and ligand were studied, and the ratio of Tb3+ and the ligand had an obvious impact on the luminescence intensity of the 10-UA-Tb(III) complex. …”
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294
The Role of PPARα Activation in Liver and Muscle
Published 2010-01-01“…It is a sensor for changes in levels of fatty acids and their derivatives that responds to ligand binding with PPAR target gene transcription, inasmuch as it can influence physiological homeostasis, including lipid and carbohydrate metabolism in various tissues. …”
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295
Inflammatory Serum Biomarkers in Colorectal Cancer in Kazakhstan Population
Published 2020-01-01“…The following biomarkers were included in the study panel: stem cell factor (SCF), vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF2), interleukin 6 (IL6), interleukin 8 (IL8), macrophage migration inhibitory factor (MIF), soluble Fas (SFAS), soluble Fas ligand (sFASL), transforming growth factor β (TGF), tumor necrosis factor (TNF), TNF-related apoptosis-inducing ligand (TRAIL), and programmed death ligand 1 (PD-L1). …”
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296
Optimizing synthesis parameters to compare Ag2V4O11/AgVO3 nanosheets for electrochemical energy storage
Published 2025-04-01“…The TrenSal ligand prepared by tris(2-aminoethyl) amine and salicylaldehyde. …”
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297
Cu(II) and Ni(II) Complexes with New Tridentate NNS Thiosemicarbazones: Synthesis, Characterisation, DNA Interaction, and Antibacterial Activity
Published 2019-01-01“…This paper reports the synthesis and detailed characterisation of copper(II) and nickel(II) complexes with tridentate thiosemicarbazone ligands H2L1 and H2L2 derived from 2-acetylpyrazine. …”
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298
Role of Peroxisome Proliferator-Activated Receptor β/δ and B-Cell Lymphoma-6 in Regulation of Genes Involved in Metastasis and Migration in Pancreatic Cancer Cells
Published 2013-01-01“…PPARβ/δ is a ligand-activated transcription factor that regulates various cellular functions via induction of target genes directly or in concert with its associated transcriptional repressor, BCL-6. …”
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299
A DFT Study of Structural and Bonding Properties of Complexes Obtained from First-Row Transition Metal Chelation by 3-Alkyl-4-phenylacetylamino-4,5-dihydro-1H-1,2,4-triazol-5-one a...
Published 2017-01-01“…Density functional calculations were used to explore the complexation of 3-alkyl-4-phenylacetylamino-4,5-dihydro-1h-1,2,4-triazol-5-one (ADPHT) derivatives by first-row transition metal cations. Neutral ADPHT ligand and mono deprotonated ligands have been used. …”
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300
Computational and In silico study of novel fungicides against combating root rot, gray mold, fusarium wilt, and cereal rust.
Published 2025-01-01“…First of all, the DFT was employed to optimize the molecular geometry, and get the prepared optimized ligand. From the DFT data, the chemical descriptors were calculated. …”
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