Synthesis and Structural Studies on Transition Metal Complexes Derived from 4-Hydroxy-4-methyl–2-pentanone-1H-benzimidazol-2-yl-hydrazone by M. Neelamma, P. Venkateswar Rao, G. H. Anuradha

“…Infrared spectral data suggest that the ligand HPBH behaves as a monobasic tridentate ligand with N: N: O donor sequence towards the metal ions. …”
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Synthesis, Physical Characterization of M(III) Transition Metal Complexes Derived from Thiodihydrazide and 5-tert-Butyl-2-hydroxy-3-(3-phenylpent-3-yl) Benzaldehyde by Gajendra Kumar, Rajeev Johari, Shoma Devi

“…A Schiff base ligand was synthesized by reacting 5-tert-butl-2-hydroxy-3-(3-phenylpent-3-yl) benzaldehyde and thiodihydrazide (2:1) and a series of metal complexes with this new ligand were synthesized by reaction with Cr (III), Mn (III), and Fe (III) metal salt in methanolic medium. …”
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Synthesis, Characterization, and Dielectric Behaviors of 4-Diethanolaminomethyl Styrene and Benzyl Methacrylate Copolymer and Its Metal Complexes by Aslisah Acikses, Fethiye Öksüz

“…The XRD patterns of ligand and metal complexes showed that they were of an amorphous nature. …”
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Complexes of a piperazine based macrocycle as Cu-Zn SOD biomimetic: approach by constants determination by Armando Ferrer Serrano, Ilena Alica García Del Toro

“…In the present work, the study of a ligand with a piperazine fragment and its Cu(II) and Zn(II) complexes is introduced. …”
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Biosensitivity and Theoretical Electronic Structure Investigations on 3-(2-Hydroxyphenyl)-2-iminothiazolidin-4-one and Its Zn2+ and Cd2+ Metal Complexes by Zewdu Bezu Gemechu, Boobalan Maria Susai, Abi M. Taddesse, Endale Teju Bedada, R. Ramamoorthy

“…The Zn2+ and Cd2+ complexes with a metal : ligands ratio of 1 : 4 were synthesized in ethanol using respective metal precursors with the title ligand. …”
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Co(II) Complex of Mefloquine Hydrochloride: Synthesis, Antimicrobial Potential, Antimalaria and Toxicological Activities by Adediji J. Femi, Obaleye J. Ayoola

“…Infrared spectral data also suggest that the ligand (mefloquine hydrochloride) behaves as a tridentate ligand with N:N:O donor sequence towards the metal ion. …”
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Antimicrobial Applications of Transition Metal Complexes of Benzothiazole Based Terpolymer: Synthesis, Characterization, and Effect on Bacterial and Fungal Strains by Mohamed A. Riswan Ahamed, Raja S. Azarudeen, N. Mujafar Kani

“…Gel permeation chromatography was used to determine the molecular weight of the ligand. The surface features and crystalline behavior of the ligand and its complexes were analyzed by scanning electron microscope and X-ray diffraction methods. …”
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NKG2D Signaling Leads to NK Cell Mediated Lysis of Childhood AML by Patrick Schlegel, Kerstin Ditthard, Peter Lang, Markus Mezger, Sebastian Michaelis, Rupert Handgretinger, Matthias Pfeiffer

“…Furthermore, a significant positive correlation of NKG2D ligand expression and blast cytolysis was shown. No impact of KIR ligand-ligand mismatch was found but a significantly increased lysis of homozygous C2 blasts by KIR2DL1 negative NK cells (donor B) was revealed. …”
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Peroxisome Proliferator-Activated Receptor-𝛾 Is a Potent Target for Prevention and Treatment in Human Prostate and Testicular Cancer by Masahide Matsuyama, Rikio Yoshimura

“…Peroxisome proliferator-activated receptor-𝛾 (PPAR)-𝛾 is a ligand-activated transcriptional factor belonging to steroid receptor superfamily. …”
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Synthesis, Crystal Structure, and Spectra Properties of the Cadmium (II) Complex with Bis(N-allylbenzimidazol-2-ylmethyl)benzylamine by Huilu Wu, Jingkun Yuan, Ying Bai, Fan Kou, Fei Jia, Bin Liu

“…In the complex, the coordination sphere around Cd (II) is distorted octahedral, six nitrogen atoms involved in coordination afforded by two tridentate ligand babb. Moreover, The DNA-binding properties of the ligand babb and Cd (II) complex were investigated by spectrophotometric methods and viscosity measurements, and the results suggest that they bind to DNA via an intercalation binding mode, and the Cd (II) complex shows higher affinity than the ligand.…”
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Synthesis and Characterization of Some Ni(II) and Cu(II) Complexes with 2-[(4-Aminophenyl)imino]-1, 2-diphenyl-1-ethanone by K. M. Khalifa, A. M. Hamil, A. Gasem, A. Abdulsalam

“…The present work deals with synthesis and characterization of the ligand 2-[(4-aminophnyl)imino]-1,2-diphenyl-1-ethanone and their complexes with Ni(II) and Cu(II) ions. …”
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Epigenetics and Breast Cancers by An T. Vo, Richard M. Millis

“…Hypermethylation at the CpG islands found in estrogen response element (ERE) promoters occurs in conjunction with ligand-bonded alpha subunit estrogen receptor (Erα) dimers wherein the ligand ERα dimer complex acts as a transcription factor and binds to the ERE promoter. …”
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Molecular docking of ferulic acid, bakuchiol and niazirin on peroxisome proliferator-activated receptor gamma (PPAR-γ) as anti-diabetic agents by Anjar Hermadi Saputro, Riri Fauziyya, Sarmoko, Iwan Syahjoko Saputra

“…The native ligand-2PRG and pioglitazone-2PRG complexes exhibited superior hydrogen bond numbers and shorter bond distances compared to the other compounds. …”
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3D-Metal Complexes Derived from Proton Pump Inhibitors-Synthesis, Characterization and Biological Studies by Suman Malik, Supriya Das, Archana Singh, Liviu Mitu

“…The effect of metals on the antimicrobial activity of the ligand has been discussed.…”
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(η6-Benzene)chlorido[2-(pyridin-2-yl)quinoline-κ2N,N′]ruthenium(II) tetrafluoridoborate by Manikandan Varadhan, Ibanpynhunlang Passi, Thangaraja Chinnathangavel, Venugopal Rajendiran

“…The title compound, [RuCl(C6H6)(C14H10N2)]BF4 or [Ru(η6-benzene)(L)Cl]+BF4− [where L denotes the 2-(pyridin-2-yl)quinoline ligand], crystallizes in the monoclinic space group P21/c. …”
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Linking machine learning and biophysical structural features in drug discovery by Armin Ahmadi, Shivangi Gupta, Vineetha Menon, Jerome Baudry

“…By leveraging pharmacophore descriptors, the AI/ML framework prioritized features uniquely associated with ligand-selected conformations, enabling a mechanism-driven understanding of binding interactions. …”
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Synthesis and characterization of cis-bisdiphenylphosphinoethene gold(I) complexes by Fayet, Océane Yvonne Odette, Crespi, Stefano, Orthaber, Andreas

“…A series of solid-state structures of gold(I) complexes using the semi-rigid cis-1,2- bis(diphenylphosphino)ethene (= cis-bdppe) ligand are reported. The proximity of the phosphine donor atoms of the bidentate ligand framework greatly favors formation of mononuclear over di- nuclear complexes. …”
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Synthesis and Characterization of Lanthanide(III) Nitrate Complexes with Terdentate ONO Donor Hydrazone Derived from 2-Benzimidazolyl Mercaptoaceto Hydrazide and o-Hydroxy Aromatic... by Vinayak M. Naik, Nirmalkumar B. Mallur

“…The experimental data sustain stoichiometry of 1:2 (metal/ligand) for the complexes. The spectral data shows that the ligand reacts in keto form and behaves as monobasic terdentate in nature. …”
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Synthesis, characterization and evaluation biological activity of some 2-mercaptobinzemidazol complexes by Anfal Salam Al-Mahdawi, Noor Sabah Al-Obaidi, Amna Ali Ahmad, Tabarak Ali Jumaa, Zahraa Ali Abas, Haider Salah Mahdi

“…The synthesized complexes were characterize by measuring ultraviolet spectroscopy, the wave length (λ nm) (318, 333.4) of ligand (272, 296.2, 624.8), (254, 306), (257, 311) and (262, 314) of synthesized complexes respectively, then by infrared spectroscopy (FTIR) the results of the infrared spectroscopic examination showed the shifted in the absorption bands of (S-H) and (N-H) groups of the ligand as a result of coordination, molar conductivity, atomic absorption (AAS) spectroscopy and ratio of elements (CHNS) to determine the formulas of the complexes, the complexes shown a distorted octahedral crystal structure, and the molecular formula of the complexes was [M (C7H6N2S)2Cl2]. …”
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Elucidating the potential of EGFR mutated NSCLC and identifying its multitargeted inhibitors by Anakha D. Rajeeve, Ramasamy Yamuna, P. K. Krishnan Namboori

“…In addition, MMPBSA/MMGBSA analysis confirmed the thermodynamic stability of each curcumin and CB[2]UN protein-ligand complex. Finally, KDeep absolute binding affinity calculations show energies of -6.13 kcal/mol and − 5.26 kcal/mol for 2ITX-CUR and 2ITV-CB[2]UN protein-ligand complexes, respectively. …”
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