Lower respiratory tract microbiome dysbiosis impairs clinical responses to immune checkpoint blockade in advanced non‐small‐cell lung cancer by Yong Zhang, Xiang‐Xiang Chen, Ruo Chen, Ling Li, Qing Ju, Dan Qiu, Yuan Wang, Peng‐Yu Jing, Ning Chang, Min Wang, Jian Zhang, Zhi‐Nan Chen, Ke Wang

“…Conclusions This study provided a microecological landscape of the lower respiratory tract with advanced NSCLC to ICI interventions and presented a multidimensional perspective with favoured outcomes that may improve the predictive capacity of the localized microbiome in clinical practices. …”
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Challenges and Strategies Adopted for Remote Teaching of Biochemistry During the COVID-19 Pandemic: Protocol for a Scoping Review by Tatiane Iembo, Helena Landim Gonçalves Cristóvão, Emerson Roberto dos Santos, André Bavaresco Gonçalves Cristóvão, Nathália Bavaresco Gonçalves Cristóvão, Cíntia Canato Martins, Natália Almeida de Arnaldo Silva Rodrigues Castro, Fernando Nestor Facio Júnior, Antônio Hélio Oliani, Alba Regina de Abreu Lima, Vânia Maria Sabadoto Brienze, Doroteia Rossi Silva Souza, Júlio César André

“… BackgroundIn March 2020, the global landscape witnessed widespread upheavals in both socioeconomic and educational spheres due to the onset of the COVID-19 pandemic. …”
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Genome assembly of an endemic butterfly (Minois aurata) shed light on the genetic mechanisms underlying ecological adaptation to arid valley habitat by Wenqian Hu, Yi Wang, Xiaoxiao Chen, Jialong Huang, Jingge Kuang, Lei Wang, Kangshan Mao, Liang Dou

“…Abstract Background The Hengduan Mountains, one of the global biodiversity hotspots with exceptional species richness and high endemism, contains numerous arid valleys that create a distinctive geographical and ecological landscape. However, the adaptive evolutionary mechanisms of organism in the arid valley remain poorly understood. …”
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Early assessment of IL8 and PD1+ Treg predicts response and guides treatment monitoring in cemiplimab-treated cutaneous squamous cell carcinoma by Teresa Troiani, Fabiana Napolitano, Luigi Formisano, Roberto Bianco, Daniela Russo, Daniela Esposito, Giuseppe Ercolano, Angela Ianaro, Alberto Servetto, Daniela Claudia Maresca, Marcella Scala, Annarita Amato, Stefania Belli, Claudia Maria Ascione, Angela Vallefuoco, Giovanna Attanasio, Fabio Somma, Silvia Varricchio, Massimo Mascolo, Claudia Costa, Alessia Villani, Massimiliano Scalvenzi, Gianfranco Orlandino

“…However, reliable biomarkers for patient selection are still lacking.Experimental design In this translational study, clinical annotations, tissue and liquid biopsies were acquired to investigate the association between sustained objective responses and transcriptional profiles, immune cell dynamics in tumor tissue and peripheral blood samples, as well as circulating cytokine levels.Results First, we investigated the baseline characteristics of the immune landscape of cSCC biopsies. Gene Set Enrichment Analysis showed upregulation of interleukin (IL)2/STAT5 pathways and downregulation of Interferon signatures in non-responder patients compared with responders. …”
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Ecological networks construction and optimization in the Longdong Loess Plateau: The advantages of self-organizing map and complex networks by Xueyu Huang, Lina Xiu, Zhixiang Lu, Jiahui Wang

“…The additional corridors also serve as an important reference for enhancing regional landscape connectivity and ecological security.…”
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Investigating intra‐tumoural heterogeneity and microenvironment diversity in primary cardiac angiosarcoma through single‐cell RNA sequencing by Jingyuan Huo, Zhen Wang, Wenting Zhao, Miao Chen, Haoyang Li, Fengpu He, Xiao Tian, Yaqi Ma, Firyuza Husanova, Liang Ma, Yiming Ni, Hongda Ding, Weidong Li, Hongfei Xu

“…Conclusion This study elucidates the complex cellular landscape and immune microenvironment of PCAS, highlighting potential molecular targets for the development of novel therapies. …”
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Management of chimeric antigen receptor T-cell-related toxicity of a patient affected by cytokine release syndrome and immune effector cell-associated neurotoxicity syndrome, follo... by G. Menardi, A. Castellino, C. Castellino, M. E. Bersia, E. Grande, G. Fraternali, M. Massaia, C. Fruttero

“…The study emphasizes the evolving landscape of chimeric antigen receptor T-cell therapy and the significance of addressing toxicities associated with this innovative treatment approach. …”
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Epidemics In The 21st Century: A Multifaceted Challenge by Shawana Sharif

“…Amidst the convoluted landscape of epidemics, medical professionals confront an amalgamation of challenges. …”
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Inhibition of histone deacetylase in Arabidopsis root calli promotes de novo shoot organogenesis by Qinwei Pan, Ruirui Huang, Qiong Xiao, Xuting Wu, Baoxia Jian, Yanan Xiang, Lijun Gan, Zongrang Liu, Yi Li, Tingting Gu, Huawei Liu, Huawei Liu

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Cultural revitalization for tourism development from an Indigenous perspective: the case of Ta Oi people, A Luoi District, Thua Thien Hue province, Vietnam by Thu-Suong Thi Nguyen, Diem-Huong Thi Phan, Diem-Huong Thi Phan, Diem-Hang Le Doan, Diem-Hang Le Doan, Minh-Ngoc Thi Chau, Thanh-Thuy Thi (Jessica) Doan, Thanh-Thuy Thi (Jessica) Doan

“…The data were analyzed thematically.ResultsThe findings reveal that the Ta Oi people have revitalized four key cultural practices through tourism, including Dzeng weaving, traditional landscapes and architecture, traditional cuisine, and traditional art performances, rituals, and beliefs. …”
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Extent, Distribution, and Causes of Soil Acidity under Subsistence Farming System and Lime Recommendation: The Case in Wolaita, Southern Ethiopia by Fanuel Laekemariam, Kibebew Kibret

“…Results revealed that the landscape is characterized by a gentle slope followed by strongly sloppy > flat > hilly topographies. …”
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英國、臺灣、馬來西亞戶外冒險教育發展之 比較分析 A Comparative Analysis on Outdoor Adventure Education Development in England, Taiwan, and Malaysia by 李晟瑋 Cheng-Wei Li, 葉優寧 Evelyn Yeap Ewe Lin

“…Additionally, the study highlighted the significance of considering cultural, societal, and policy contexts in shaping the landscape of OAE in diverse educational systems. The findings of the study recommend that the Ministry of Education of Malaysia reassess the implementation of OAE in a more holistic manner. …”
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Ethnobotanical studies on rice landraces under on-farm conservation in Xishuangbanna of Yunnan Province, China by Fei Wang, Tao Sun, Shuai Yu, Chunhui Liu, Zhuo Cheng, Jianxin Xia, Longzhi Han

“…Abstract Background A complex interaction and mutual influence exists among landscapes, cultures, and landraces, with rice culture being a typical embodiment of this relationship. …”
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Characteristics of Land Use Change and Evaluation of Ecological Sensitivity in Chongqing by XIE Xianjian, GOU Qiantao, WU Han

“…[Results] (1) In the study area, the landscape matrix was predominantly composed of farmland, accounting for more than 45% of the total area. …”
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Les voyages reproductifs vers la Tunisie : l’intime au prisme des pratiques de l’assistance médicale à la procréation by Irene Maffi, Betty Rouland, Carole Wenger

“…Articulated by the infertile North African and West African couples encountered, the transnational reproductive landscapes analysed in the paper offer an original perspective to approach the intimate in the Maghreb. …”
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Les Jeunes Tunisiens, une contre-expérience de la minoration ? Politisation des langues dans la presse francophone en Tunisie coloniale (1907-1912) by Sarra Zaïed

“…Les Jeunes Tunisiens (the Young Tunisians) laid the groundwork for a mobilisation of the political landscape of colonial Tunisia at the beginning of the 20th century. …”
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Development and validation of soil test crop response model for beetroot (Beta vulgaris) grown in ultisols of India by Ramasamy Arulmani, Ramasamy Arulmani, Kuppayevalasu Malayappagounder Sellamuthu, Kuppayevalasu Malayappagounder Sellamuthu, Subramaniam Maragatham, Subramaniam Maragatham, Alargarsamy Senthil, Alargarsamy Senthil, Seenapuram Palaniswami Thamaraiselvi, Seenapuram Palaniswami Thamaraiselvi, Palaniappan Malathi, Palaniappan Malathi, Govindaraja Sridevi, Govindaraja Sridevi

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Analisis Framing Pemberitaan Program Kerja Makan Siang Gratis Prabowo-Gibran Dalam Media Online Liputan6.Com Dan Republika.co.id by Fadisa Rahma Devi Triana, Muhammad Thoyib Amali

“…The 2024 presidential election is becoming an important moment in the political landscape of Indonesia. Where Prabowo Subianto and Gibran Rakabuming Raka successfully won the majority of votes. …”
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A synthesis of academic literature on eco-spirituality by A.H.A. Adow, M.M. Safeer, M.G.H. Mohammed, M. Sayeed Alam, M.M. Sulphey

“…Publications predominantly originated from the United States, the United Kingdom, Canada, India, and Switzerland, reflecting global interest and engagement across diverse cultural landscapes. Key journals, including Religions, emerged as prominent platforms, underscoring the interdisciplinary nature of eco-spirituality research. …”
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Decarbonizing Saudi Arabia energy and industrial sectors: Assessment of carbon capture cost by Feras Rowaihy, Ali Hamieh, Naser Odeh, Mohamad Hejazi, Mohammed Al-Juaied, Abdulkader M. Afifi, Hussein Hoteit

“…Benchmarking against global capture costs reveals that Saudi Arabia's industrial landscape, characterized by large-scale emitters, is well-positioned for cost-effective CCUS implementation. …”
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