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Anti-microbial cetylpyridinium chloride suppresses mast cell function by targeting tyrosine phosphorylation of Syk kinase
Published 2024-12-01Subjects: Get full text
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103
Lipid Storage Myopathy in Behçet's Disease: A Rare Cause of Elevated Serum Creatine Kinases Levels
Published 2012-01-01Get full text
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104
A review on the potential of Bruton’s tyrosine kinase (Btk) inhibitor – Ibrutinib for treatment of Multiple Myeloma (MM)
Published 2019-05-01“…Nonetheless, research on novel therapies for effective treatment of MM is ongoing and in this case the involvement of Bruton’s tyrosine kinase (Btk) in B-cell malignancies has made it one of the new therapeutic targets. …”
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105
Contents of plasma М2-pyruvate kinase (M2-РК) in patients with inflammatory bowel diseases
Published 2010-11-01Subjects: Get full text
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106
Hepatocyte Rho-associated kinase signaling is required for mice to survive experimental porphyria-associated liver injury
Published 2025-02-01“…Background:. Rho-associated kinases 1 and 2 (ROCK1 and ROCK2) regulate critical cell functions, including actomyosin contractility, apoptosis, and proliferation. …”
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107
Protein Kinase Cα Modulates Estrogen-Receptor-Dependent Transcription and Proliferation in Endometrial Cancer Cells
Published 2013-01-01“…We have shown that protein kinase Cα (PKCα) is aberrantly expressed in endometrioid tumors and is an important mediator of endometrial cancer cell survival, proliferation, and invasion. …”
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108
Role of Mitogen-Activated Protein Kinase Pathways in Multifactorial Adverse Cardiac Remodeling Associated with Metabolic Syndrome
Published 2013-01-01“…Amongst the different intracellular kinases, mitogen-activated protein kinases (MAPKs) were shown to be involved in heart damage in metabolic syndrome. …”
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109
Possible bi-directional link between ETA receptors and protein kinase C in rat blood vessels
Published 1995-01-01“…Possible links have been investigated between activation of protein kinase C (PKC) and endothelin (ET) production by small blood vessels. …”
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110
Beta 3 adrenoreceptors protect from hypertrophic remodelling through AMP‐activated protein kinase and autophagy
Published 2020-06-01Subjects: Get full text
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111
Utility of Bruton’s Tyrosine Kinase Inhibitors in Light Chain Amyloidosis Caused by Lymphoplasmacytic Lymphoma (Waldenström’s Macroglobulinemia)
Published 2022-01-01“…BTK is a nonreceptor kinase involved in B-cell survival, proliferation, and interaction with the microenvironment. …”
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112
The Interaction of Src Kinase with β3 Integrin Tails: A Potential Therapeutic Target in Thrombosis and Cancer
Published 2010-01-01“…Activation of Src family kinases is an important event downstream of integrin adhesion signaling in many cell types. …”
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Icaritin alleviates motor impairment and osteoporosis in Parkinson’s disease mice via the ER-PI3K/Akt pathway
Published 2025-01-01Subjects: Get full text
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115
Comparative safety profile of tyrosine kinase inhibitors in NSCLC: a network meta-analysis of hypertension and thrombotic risks
Published 2025-01-01Subjects: Get full text
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116
Effect of Antrodia camphorata on Inflammatory Arterial Thrombosis-Mediated Platelet Activation: The Pivotal Role of Protein Kinase C
Published 2014-01-01“…Antrodia camphorata inhibited collagen-induced calcium (Ca2+) mobilization and phosphorylation of protein kinase C (PKC) and Akt. In addition, Antrodia camphorata significantly reduced the aggregation and phosphorylation of PKC in phorbol-12, 13-dibutyrate (PDBu) activated platelets. …”
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Rechallenge therapy versus tyrosine kinase inhibitor (TKI) for advanced metastatic colorectal cancer: a retrospective study
Published 2025-02-01Subjects: “…Tyrosine kinase inhibitor…”
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118
Deformed wing virus coopts the host arginine kinase to enhance its fitness in honey bees (Apis mellifera)
Published 2025-01-01“…Among the co-immunoprecipitated proteins, one of the most interesting was arginine kinase (ArgK), a conserved protein playing multiple roles both in physiological and pathological processes and stress response in general. …”
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Remodeling of tumor microenvironments by EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer
Published 2025-02-01“…We used digital spatial profiling to analyze non-small cell lung carcinomas in 25 patients before and after EGFR tyrosine kinase inhibitor (TKI) treatment, including 14 patients treated with first-line osimertinib, focusing on CD45-positive immune regions and pan-cytokeratin-positive tumor regions. …”
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Cardiovascular safety of Janus kinase inhibitors in inflammatory bowel disease: a systematic review and network meta-analysis
Published 2025-12-01Subjects: Get full text
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