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Crosstalk between Substrates and Rho-Associated Kinase Inhibitors in Cryopreservation of Tissue-Engineered Constructs
Published 2017-01-01“…Several natural and synthetic materials are extensively used as substrates for tissue engineering constructs and cryopreservation because they promote cell attachment and proliferation. Rho-associated kinase (ROCK) inhibitors can improve the physiological function and postthaw viability of cryopreserved MSCs. …”
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62
Clinical relevance and druggability of sole reciprocal kinase fusions: A large‐scale study
Published 2024-09-01“…Abstract Background Building on our prior work that RNA alternative splicing modulates the druggability of kinase fusions, this study probes the clinical significance of sole reciprocal fusions. …”
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63
Janus kinase inhibitor treatment for inflammatory diseases: excess or no excess risk of venous thromboembolism?
Published 2025-01-01Subjects: Get full text
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64
High Expression of Polo-Like Kinase 1 Is Associated with Early Development of Hepatocellular Carcinoma
Published 2014-01-01“…Polo-like kinase 1 (PLK1), one of serine/threonine-protein kinase, has been demonstrated to play pivotal roles in malignant transformation. …”
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65
FDA-approved kinase inhibitors: a promising therapeutic avenue for traumatic brain injury
Published 2024-12-01Subjects: Get full text
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66
Identification of Protein Kinase C Isoforms Involved in Type 1 Diabetic Encephalopathy in Mice
Published 2018-01-01“…Diabetic encephalopathy is a complication of diabetes mellitus characterized by impaired cognitive functions. Protein kinase C (PKC) isoforms are rarely reported on diabetic encephalopathy, although they have been believed to play crucial roles in other diabetic complications. …”
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67
Effect of Kinases in Extracellular Vesicles from HIV-1-Infected Cells on Bystander Cells
Published 2025-01-01Subjects: Get full text
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68
Sleep in Genetically Confirmed Pantothenate Kinase-Associated Neurodegeneration: A Video-Polysomnographic Study
Published 2010-01-01“…Pantothenate kinase-associated neurodegeneration (PKAN) is a familial or sporadic disease characterized by extrapyramidal and corticospinal signs with dementia. …”
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Increased risk of Pneumocystis jirovecii colonization in rheumatoid arthritis patients on biologics and Janus kinase inhibitor
Published 2025-02-01Subjects: Get full text
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71
Functional Characterization of the Canine Heme-Regulated eIF2α Kinase: Regulation of Protein Synthesis
Published 2009-01-01“…Quercetin, a kinase inhibitor known to inhibit mouse and human HRI, inhibits canine HRI in a concentration-dependent manner. …”
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72
Identification of novel cyclin-dependent kinase 4/6 inhibitors from marine natural products
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73
Protein Kinase CK2: A Targetable BCR-ABL Partner in Philadelphia Positive Leukemias
Published 2015-01-01“…Here, we review the role of BCR-ABL/protein kinase CK2 interaction in BCR-ABL leukemias, with potentially relevant implications for therapy.…”
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Role of Mitogen-Activated Protein Kinases in Myocardial Ischemia-Reperfusion Injury during Heart Transplantation
Published 2012-01-01“…The four best-characterized MAPK subfamilies are the c-Jun NH2-terminal kinase (JNK), extracellular signal- regulated kinase-1/2 (ERK1/2), p38 MAPK, and big MAPK-1 (BMK1/ERK5). …”
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75
Gambaran Kadar Troponin T dan Creatinin Kinase Myocardial Band pada Infark Miokard Akut
Published 2014-09-01“…Diagnosis IMA dapat dilakukan dengan cara: anamnesis, abnormalitas Elektrokardiogram (EKG), peningkatan Creatinin Kinase Myocardial Band (CKMB), dan cardiac specific troponin (cTn)T. …”
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76
Metabolic Basis for Thyroid Hormone Liver Preconditioning: Upregulation of AMP-Activated Protein Kinase Signaling
Published 2012-01-01“…In this context, adenosine-monophosphate- (AMP-) activated protein kinase (AMPK) constitutes an intrahepatic energy sensor regulating physiological energy dynamics by limiting anabolism and stimulating catabolism, thus increasing ATP availability. …”
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77
Two Cysteines in Raf Kinase Inhibitor Protein Make Differential Contributions to Structural Dynamics In Vitro
Published 2025-01-01Subjects: “…Raf kinase inhibitor protein…”
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78
ERK1/2 mitogen‐activated protein kinase dimerization is essential for the regulation of cell motility
Published 2025-02-01Subjects: Get full text
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79
Pengaruh Likopen terhadap Kadar Soluble FMS-Like Tyrosine Kinase 1 pada Preeklamsi
Published 2021-02-01Get full text
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80
Biomimetic polydopamine loaded with janus kinase inhibitor for synergistic vitiligo therapy via hydrogel microneedles
Published 2025-01-01“…Additionally, the accumulated CD8+ T cells release interferon-γ (IFN-γ) to activate janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway in keratinocytes. …”
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