Dynamic co-evolution of transposable elements and the piRNA pathway in African cichlid fishes by Miguel Vasconcelos Almeida, Moritz Blumer, Chengwei Ulrika Yuan, Pío Sierra, Jonathan L. Price, Fu Xiang Quah, Aleksandr Friman, Alexandra Dallaire, Grégoire Vernaz, Audrey L. K. Putman, Alan M. Smith, Domino A. Joyce, Falk Butter, Astrid D. Haase, Richard Durbin, M. Emília Santos, Eric A. Miska

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Procalcitonin and High APACHE (Acute Physiological and Chronic Health Evaluation) Level Are Associated with the Course of Acute Kidney Injury in Patients with SARS-CoV-2 by Jorge Andrade Sierra, Claudia Delgado Astorga, Miriam Gabriela Nava Vargas, Enrique Rojas Campos, Kevin Javier Arrelano Arteaga, Karla Hernández Morales, Carlos A. Andrade Castellanos, Antonio de Jesús Andrade-Ortega, Luis Gerardo González Correa

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Exploring Potential Complement Modulation Strategies for Ischemia–Reperfusion Injury in Kidney Transplantation by Dario Troise, Costanza Allegra, Luciana Antonia Cirolla, Silvia Mercuri, Barbara Infante, Giuseppe Castellano, Giovanni Stallone

“…Currently, complement-modulating drugs are under investigation for the treatment of kidney diseases. Many of these drugs have shown potential therapeutic benefits, but no effective clinical treatments for renal IRI have been identified yet. …”
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The Interplay of Renin-Angiotensin System and Toll-Like Receptor 4 in the Inflammation of Diabetic Nephropathy by Qi Feng, Dongwei Liu, Yanfang Lu, Zhangsuo Liu

“…Diabetic nephropathy (DN) is one of the most serious chronic kidney diseases and the major cause of end-stage renal failure worldwide. …”
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Induction of Oxidative Stress in Kidney by Emin Ozbek

“…Oxidative stress has a critical role in the pathophysiology of several kidney diseases, and many complications of these diseases are mediated by oxidative stress, oxidative stress-related mediators, and inflammation. …”
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Drug-Induced Hematological Cytopenia in Kidney Transplantation and the Challenges It Poses for Kidney Transplant Physicians by Muhammad Abdul Mabood Khalil, Muhammad Ashhad Ullah Khalil, Taqi F. Taufeeq Khan, Jackson Tan

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Role of PPARα and Its Agonist in Renal Diseases by Ching-Feng Cheng, Hsi-Hsien Chen, Heng Lin

“…This paper focuses on signaling pathways, ligand selectivity, and physio-pathological roles of PPARα in kidney diseases and the therapeutic utility of PPARα modulators in the treatment of diabetes and inflammation-induced nephropathy. …”
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TDP43 augments astrocyte inflammatory activity through mtDNA-cGAS-STING axis in NMOSD by Zhuhe Liu, Yunmeng Bai, Bingtian Xu, Haixia Wen, Kechun Chen, Jingfang Lin, Yuanyuan Wang, Jiangping Xu, Haitao Wang, Fudong Shi, Jigang Wang, Honghao Wang

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Diabetes Prediction Through Linkage of Causal Discovery and Inference Model with Machine Learning Models by Mi Jin Noh, Yang Sok Kim

“…<b>Methods</b>: Kaggle’s dataset from the National Institute of Diabetes and Digestive and Kidney Diseases was analyzed using logistic regression, deep learning, gradient boosting, and decision trees. …”
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Potential Nephroprotective Effect of Kaempferol: Biosynthesis, Mechanisms of Action, and Clinical Prospects by Maulana Yusuf Alkandahri, Asman Sadino, Barolym Tri Pamungkas, Zulpakor Oktoba, Maya Arfania, Nia Yuniarsih, Eko Sri Wahyuningsih, Yuliani Dewi, Sri Ayu Winarti, Sri Tantia Dinita

“…Natural drugs are currently being explored as a new therapeutic strategy for managing kidney diseases. Kaempferol, a polyphenol found in plants, including vegetables, legumes, and fruits, has been extensively studied in various nephrotoxicity protocols. …”
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C-SHAP: A Hybrid Method for Fast and Efficient Interpretability by Golshid Ranjbaran, Diego Reforgiato Recupero, Chanchal K. Roy, Kevin A. Schneider

“…Notably, in the Diabetes dataset collected by the National Institute of Diabetes and Digestive and Kidney Diseases, C-SHAP reduces the execution time from nearly 2000 s to just 0.21 s, underscoring its potential for scalable, efficient interpretability in time-sensitive applications. …”
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Hypertensive Response to Exercise as an Early Marker of Disease Development by Wojciech Kosowski, Krzysztof Aleksandrowicz

“…With the number of people living with this disease doubling between 1990 and 2019 from 650 million to 1.3 billion, it is a global burden that increases mortality from cardiovascular and kidney diseases. It is extremely important to use all possible diagnostic methods, indicating the possibility of early detection that subsequently leads to effective prevention of disease development. …”
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Focal Xanthogranulomatous Pyelonephritis with Pulmonary Lesions on the Background of Type Two Diabetes Mellitus by Ahmad Enshaei, Arash A. Boora, Diana Taheri, Zahra Changizi, Nahid Bahmani

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Readiness of Sub-Saharan Africa Healthcare Systems for the New Pandemic, Diabetes: A Systematic Review by Bernardo Nuche-Berenguer, Linda E. Kupfer

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Natural products targeting ubiquitination to combat kidney fibrosis by Lianhua Li, Xinhui Huang, Yao Chen, Jibin Liu, Yuhang Qiao, Wenyu Fan, Peiqing Zhang, Xiaoming Yan, Ming Chen

“…Abstract Background Kidney fibrosis is a crucial component that contributes to end-stage renal disease and is the inevitable last pathological process in many progressive chronic kidney diseases (CKD). Ubiquitination, one of the most refined and widespread reversible post-translational modifications, plays a significant role in the development of renal fibrosis through its regulation and deubiquitination processes. …”
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Chemokines in Renal Diseases by Stephan Segerer, Peter J. Nelson

“…Chemokine receptor blockade has approached clinical applications in nonrenal diseases and awaits the application in patients with kidney diseases.…”
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Cryo-electron tomography pipeline for plasma membranes by Willy W. Sun, Dennis J. Michalak, Kem A. Sochacki, Prasanthi Kunamaneni, Marco A. Alfonzo-Méndez, Andreas M. Arnold, Marie-Paule Strub, Jenny E. Hinshaw, Justin W. Taraska

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Performance Analysis of Diabetes Detection Using Machine Learning Classifiers by Hung Huynh, Liu Hui, Ngoc Han Nguyen, Ruixuan Qiao

“…This study purports to fill that gap by looking at various machine learning (ML) algorithms and applying them on the PIMA Indians Diabetes Dataset provided by the National Health Institute of Diabetes and Digestive and Kidney Diseases with the aim of improving the validity of diabetes prediction and diagnosis. …”
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Hepatitis B Virus-Related Glomerulonephritis: Not a Predominant Cause of Proteinuria in Korean Patients with Chronic Hepatitis B by Jeong-Ju Yoo, Jeong-Hoon Lee, Jung-Hwan Yoon, Minjong Lee, Dong Hyeon Lee, Yuri Cho, Eun Sun Jang, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim, Hyo-Suk Lee

“…However, proteinuria can occur because of other kidney diseases besides HBV-related GN (HBV-GN). The aim of this study is to elucidate the causes of proteinuria and report on the clinical outcomes of HBV-GN. …”
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Increased RTN3 phenocopies nonalcoholic fatty liver disease by inhibiting the AMPK–IDH2 pathway by Hao Huang, Shuai Guo, Ya‐Qin Chen, Yu‐Xing Liu, Jie‐Yuan Jin, Yun Liang, Liang‐Liang Fan, Rong Xiang

“…Abstract Reticulon 3 (RTN3), an endoplasmic reticulum protein, is crucial in neurodegenerative and kidney diseases. However, the role of RTN3 in liver tissues has not been described. …”
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