Evolutionary origins of synchronization for integrating information in neurons by Takashi Shibata, Takashi Shibata, Noriaki Hattori, Hisao Nishijo, Tsutomu Takahashi, Tsutomu Takahashi, Yuko Higuchi, Yuko Higuchi, Satoshi Kuroda, Kaoru Takakusaki

“…Quantum synchronization is hypothesized to involve ion coherence during ion channel passage and the entanglement of photons within the myelin sheath. …”
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Dystonia caused by ANO3 variants is due to attenuated Ca2+ influx by ORAI1 by Jiraporn Ousingsawat, Khaoula Talbi, Hilario Gómez-Martín, Anne Koy, Alberto Fernández-Jaén, Hasan Tekgül, Esra Serdaroğlu, Juan Darío Ortigoza-Escobar, Rainer Schreiber, Karl Kunzelmann

“…Abstract Background Dystonia is a common neurological hyperkinetic movement disorder that can be caused by mutations in anoctamin 3 (ANO3, TMEM16C), a phospholipid scramblase and ion channel. We previously reported patients that were heterozygous for the ANO3 variants S651N, V561L, A599D and S651N, which cause dystonia by unknown mechanisms. …”
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Analysis of a Family with Brugada Syndrome and Sudden Cardiac Death Caused by a Novel Mutation of SCN5A by Yao-Bin Zhu, Jian-Hui Zhang, Yuan-Yuan Ji, Ya-Nan Hu, Han-Lu Wang, Dan-Dan Ruan, Xiao-Rong Meng, Xin-Fu Lin, Jie-Wei Luo, Wei Chen

“…Brugada syndrome is a hereditary cardiac disease associated with mutations in ion channel genes. The clinical features include ventricular fibrillation, syncope, and sudden cardiac death. …”
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Piezo1-directed neutrophil extracellular traps regulate macrophage differentiation during influenza virus infection by Yuexin Wang, Qiuli Yang, Yingjie Dong, Likun Wang, Zhiyuan Zhang, Ruiying Niu, Yufei Wang, Yujing Bi, Guangwei Liu

“…Herein, we found that the ion channel Piezo1 directs neutrophil extracellular trap (NET) formation and regulates macrophage functional differentiation in anti-influenza virus immunity. …”
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LCZ696 Therapy Reduces Ventricular Tachyarrhythmia Inducibility in a Myocardial Infarction-Induced Heart Failure Rat Model by Po-Cheng Chang, Shien-Fong Lin, Yen Chu, Hung-Ta Wo, Hui-Ling Lee, Yu-Chang Huang, Ming-Shien Wen, Chung-Chuan Chou

“…Western blot analyses were conducted to quantify ion channel proteins. Results. The HF-vehicle group did not show significant changes in LVEF. …”
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Transcript Profiles of Stria Vascularis in Models of Waardenburg Syndrome by Linjun Chen, Lin Wang, Lei Chen, Fangyuan Wang, Fei Ji, Wei Sun, Hui Zhao, Weiju Han, Shiming Yang

“…Vascular-related and ion channel-related genes in the stria vascularis were also shown significantly difference between the two species. …”
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Ethnicity-specific distribution of <em>TRPM8</em> gene variants in Eurasian populations: signs of selection by T. A. Potapova, A. G. Romashchenko, N. S. Yudin, M. I. Voevoda

“…The TRPM8 gene encodes the ion channel, which is a cold receptor in afferent neurons of the mammalian somatosensory system. …”
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Loss of Myh14 Increases Susceptibility to Noise-Induced Hearing Loss in CBA/CaJ Mice by Xiaolong Fu, Linqing Zhang, Yecheng Jin, Xiaoyang Sun, Aizhen Zhang, Zongzhuang Wen, Yichen Zhou, Ming Xia, Jiangang Gao

“…MYH14 is a member of the myosin family, which has been implicated in many motile processes such as ion-channel gating, organelle translocation, and the cytoskeleton rearrangement. …”
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Human induced pluripotent stem cell line XXMUFAi001-A generated from a patient harboring KCNH2 mutation (c. 2690 A>C) by Xiaolei Li, Junbiao Zhang, Xiaofeng Wang, Dawei Pu, Zhenling Zhang, Yifang Niu, Shuai Zhang, Zhenping Fan, Yuxuan Li, Peicheng Li, Hui Liu, Fenghua Lv, Yongchun Zhang, Ya’nan Li

“…Long QT syndrome type 2 (LQT2), caused by mutations in the KCNH2 gene, is an inherited ion channel disorder associated with sudden death in adolescents. …”
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Piezo1 aggravates ischemia/reperfusion-induced acute kidney injury by Ca2+-dependent calpain/HIF-1α/Notch signaling by Xiaoting Chen, Jintao Jiang, Bin He, Shangfei Luo, Qiaorui Tan, Youfen Yao, Rentao Wan, Honglin Xu, Silin Liu, Xianmei Pan, Xin Chen, Jing Li

“…The mechanosensitive ion channel Piezo1 is significant in these inflammatory processes. …”
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Assessing molecular changes underlying isopropylated phenyl phosphate (IPP)-induced larval sensorimotor response deficits in zebrafish by Sunil Sharma, Alfredo Rojas, Abhishek Gour, Rosemaria Serradimigni, Connor Leong, Abhisheak Sharma, Subham Dasgupta

“…However, for eyes, mRNA sequencing showed 135 differentially expressed genes and these were enriched for several nervous system-associated pathways, including voltage gated ion channel activity, synaptic transmission and neurotransmitter signaling. …”
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Plant Compounds Inhibit the Growth of W12 Cervical Precancer Cells Containing Episomal or Integrant HPV DNA; Tanshinone IIA Synergizes with Curcumin in Cervical Cancer Cells by Linda Saxe Einbond, Jing Zhou, Kunhui Huang, Mario R. Castellanos, Emeka Mbazor, Michael Balick, Hongbao Ma, James A. DeVoti, Stephen Redenti, Hsan-au Wu

“…Molecular docking studies suggested tanshinone IIA and curcumin bind to the Na⁺/K⁺-ATPase ion channel, with curcumin binding with higher affinity. …”
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Structural insights into the mechanism of phosphate recognition and transport by XPR1 by Wenhui Zhang, Yanke Chen, Zeyuan Guan, Yong Wang, Meng Tang, Zhangmeng Du, Jie Zhang, Meng Cheng, Jiaqi Zuo, Yan Liu, Qiang Wang, Yanjun Liu, Delin Zhang, Ping Yin, Ling Ma, Zhu Liu

“…XPR1 features 10 transmembrane α-helices forming an ion channel-like structure, with multiple Pi recognition sites along the channel. …”
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Nicotine is associated with smoking dependence and vascular inflammation through cotinine: A mediation analysis by Kumboyono Kumboyono, Indah N. Chomsy, Nadya N. Shalshabilla, Hidayat Sujuti, Arie Srihardyastutie, Cholid T. Tjahjono, Teuku Heriansyah, Titin A. Wihastuti

“…Cotinine, a metabolite of nicotine, is capable of causing dependence effects through endless mechanisms modulated by the ion channel nicotinic acetylcholine receptors nAChRs. …”
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Developmental deficits, synapse and dendritic abnormalities in a Clcn4 KO autism mice model: endophenotypic target for ASD by Seong Mi Lee, Yura Choi, Dayeon Kim, Ha Jin Jeong, Young Ho Do, Sohee Jung, Bomee Lee, Hyung Jun Choi, Suhyeon Kim, Jung-Min Oh, Songhee Jeon, Jinju Han, Yeni Kim

“…Abstract Autism spectrum disorder (ASD) is linked to ion channel dysfunction, including chloride voltage-gated channel-4 (CLCN4). …”
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TRPV1 and PLC Participate in Histamine H4 Receptor-Induced Itch by Tunyu Jian, Niuniu Yang, Yan Yang, Chan Zhu, Xiaolin Yuan, Guang Yu, Changming Wang, Zhongli Wang, Hao Shi, Min Tang, Qian He, Lei Lan, Guanyi Wu, Zongxiang Tang

“…These results indicate that TRPV1 but not TRPA1 is the important ion channel to induce the DRG neurons’ responses in the downstream signaling pathway of histamine H4 receptor and suggest that TRPV1 may be involved in the mechanism of histamine-induced itch response by H4 receptor activation.…”
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Literature review: potential non-thermal molecular effects of external radiofrequency electromagnetic fields on cancer by Anna Dieper, Stephan Scheidegger, Rudolf M. Füchslin, Paraskevi D. Veltsista, Ulrike Stein, Mathias Weyland, Dominik Gerster, Marcus Beck, Olof Bengtsson, Daniel Zips, Pirus Ghadjar

“…Among those, by reviewing the included publications, we identified RF-EMF-induced ion channel activation, altered gene expression, altered membrane potentials, membrane oscillations, and blebbing, as well as changes in cytoskeletal structure and cell morphology.Conclusion The existent literature points toward a yet untapped therapeutic potential of RF-EMF treatment, which might aid in damaging cancer cells through bio-electrical and electro-mechanical molecular mechanisms while minimizing adverse effects on healthy tissue cells. …”
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The search for a blood-based biomarker for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS): from biochemistry to electrophysiology by Krista S. P. Clarke, Caroline C. Kingdon, Michael Pycraft Hughes, Eliana Mattos Lacerda, Rebecca Lewis, Emily J. Kruchek, Robert A. Dorey, Fatima H. Labeed

“…Increasing evidence demonstrates acetylcholine receptor and transient receptor potential ion channel dysfunction in ME/CFS, though how these findings could translate to a diagnostic biomarker are yet to be explored. …”
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Radiofrequency thermocoagulation of Gasserian ganglion in trigeminal neuralgia by Natalia Maria Rulewska, Filip Grabowski, Dagmara Neska, Jakub Siemko, Dominika Prystacka-Szar, Justyna Stadler-Szajda, Adrianna Czyżnikiewicz, Wenancjusz Stołowski, Magdalena Bujak, Magdalena Waśniowska, Jakub Chodkowski

“…Conclusion: The exact mechanisms behind trigeminal neuralgia are still unclear, but several theories suggest that factors such as inflammation, ion channel dysfunction, neuroinflammatory conditions, or bioresonance issues may be involved. …”
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Genetic characteristics of influenza A and B viruses circulating in Russia in 2019–2023 by Svetlana B. Yatsyshina, Anna A. Artamonova, Maria A. Elkina, Anna V. Valdokhina, Victoria P. Bulanenko, Aleksandra A. Berseneva, Vasily G. Akimkin

“…Objectives of the study include: analysis of influenza virus circulation in Russia in 2019–2023, phylogenetic and molecular analysis of hemagglutinin (HA) sequences of influenza viruses, detection of mutations associated with drug resistance to neuraminidase (NA) inhibitors and M2-protein (M2) ion channel inhibitors. Materials and methods. Biological samples containing RNA of influenza viruses were studied: 410 A(H1N1)pdm09, 147 A(H3N2) and 167 B(Victoria). …”
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