Antibiotic resistance of uropathogens in patients with nephrolithiasis and concomitant coronary heart disease by R. V. Royuk, S. K. Yarovoy, I. B. Shikina

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Enhancing Emergency Response in Road Accidents: A Severity Prediction Framework Using RF-RFE and Deep Learning Model by Chaimaa Chaoura, Hajar Lazar, Zahi Jarir

“…Rapid emergency response is crucial to mitigating their impact, especially for cases requiring urgent medical intervention. This study aims to enhance emergency response strategies by developing a model that prioritizes severe accidents, ensuring faster ambulance dispatch and timely medical assistance. …”
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Antimicrobial efficacy of ozone therapy in endodontic treatment: A systematic review by P Doshi, P Oswal, S. R. Srinidhi, M. Bhujbal, K. Malu

“…The studies including intervention using ozone therapy as irrigant and intracanal medicament and comparison with conventional root canal irrigant were included. …”
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Two-stage treatment of ametropia in patients with keratoconus and cataracts by M. M. Bikbov, O. I. Orenburkina, A. E. Babushkin, I. F. Nuriev

“…Conducting a two-stage surgical intervention in patients with keratoconus and cataracts allows to stop the progression of the disease and effectively correct the ametropia concomitant with keratoconus.…”
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Optimization of Pharmacotherapy with Direct Oral Anticoagulants: the Need to Choose the Right Dosage Regimen by A. I. Kochetkov, O. D. Ostroumova

“…In these terms, apixaban stands high among the DOAC class, and its high efficacy and safety both in full dose and reasonably reduced dosage has been proved, including older patients, patients with chronic kidney disease, coronary artery disease, with history of acute coronary syndrome and individuals undergoing percutaneous coronary intervention. This DOAC has strict indications to reduce the dose, they are specified in the drug label, and in such cases a reduced dose should be prescribed, in these clinical conditions the effectiveness and safety of apixaban is also proven. …”
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Prediction of late results of surgical treatment of traumatic retina detachment in eye injury of multiple origin by N. L. Leparskaya

“…A direct dependence of long-term functional results of treatment on the PVR stage, the area of detached retina and the diagnosed retinal rupture during the first vitreoretinal surgical intervention was established.Conclusion. In order to make the surgical treatment of TRD more effective, it is worth using antiproliferative drugs intravitreally during vitreoretinal surgery, especially in OEI A, OEI D and OGI E, when the proliferative syndrome is caused both by PVR and mooring, as well as in CEI A in the case of a pronounced PVR stage.…”
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Effect of Milk Drinking on the Level of Liver Enzymes among Workers of Paint Manufacturing Industry by MA Vahdani manesh, V Abolhasannejad, N Moasheri, D Ketabi

“…Conclusion: Considering that milk drinking was effective in reducing the level of liver enzymes among workers among workers who were chronically exposed to aromatic solvents, therefore, the present intervention can have a major role in preventing the incidence or in reducing the liver lesions among workers predisposed to risk.…”
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Comparison of the accuracy of cone-beam computed tomography, photostimulable phosphor imaging plate, charge coupled device, and conventional intraoral radiography in the diagnosis... by Abbas Shokri, Jalal Poorolajal, Farhad Faramarzi

“…Fifty seven carries-free anterior teeth were divided into three intervention groups of 15 teeth and one control group of 12 teeth. …”
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Enhancing junior doctor confidence and competence in UGIB management: a three-cycle QIP using education, prescribing protocols and care bundles by Mareen Zachariah, Natalie Chan-Lam

“…Results: Pre- and post-intervention self-assessed confidence scores improved after each teaching session. …”
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Evaluation and management of incomplete ovarian function suppression in premenopausal breast cancer patients receiving anti-hormone therapy by Ruchi Patel, Elizabeth Weil, Sara Bugamelli, Emma Carroll, Kylie Steinke, Erinn Stockhausen, John Burfeind, Colin Mooney, Janet Retseck, Deepika Sriram, Jutta Deininger, Angela Halbach, Maressa Sweeney, Sailaja Kamaraju, Lubna N. Chaudhary, Yee Chung Cheng

“…Out of the 17 patients with incomplete OFS, 14 underwent a change in their GnRH agonist as an intervention aimed at achieving complete OFS. Among these 14 patients, 7 successfully attained OFS, 5 continued to experience incomplete OFS, and 2 opted to decline future monitoring. . …”
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Monkeypox virus spreads from cell-to-cell and leads to neuronal death in human neural organoids by Isabel Schultz-Pernice, Amal Fahmi, Francisco Brito, Matthias Liniger, Yen-Chi Chiu, Teodora David, Blandina I. Oliveira Esteves, Antoinette Golomingi, Beatrice Zumkehr, Markus Gerber, Damian Jandrasits, Roland Züst, Selina Steiner, Carlos Wotzkow, Fabian Blank, Olivier B. Engler, Artur Summerfield, Nicolas Ruggli, David Baud, Marco P. Alves

“…Our findings suggest that viral disruption of neuritic transport drives neuronal degeneration, potentially contributing to MPXV neuropathology and revealing targets for therapeutic intervention.…”
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Open sternal fracture with bilateral dislocation of the sternoclavicular joints after a high-speed bicycle accident: a case report by Christian Prangenberg, Alberto Alfieri Zellner, Jonas Roos, Donatas Zalepugas, Robert Ossendorff, Soufian Ben Amar, Davide Cucchi, Sebastian Scheidt

“…Conclusions Immediate interdisciplinary intervention, including surgical repair and meticulous postoperative care, facilitated successful patient recovery. …”
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The evolution of views on the complex treatment of esophageal cancer by T. L. Sharapov, M. V. Burmistrov, E. I. Sigal, M. G. Gordiev, Ch. V. Kholomanova, V. I. Fedorov

“…Today, according to world literature, it is generally accepted that the development of anastomotic leakage is associated with the detection of the disease in late stages, the consequences of radiation during combined chemoradiotherapy, and extensive surgical intervention for esophageal cancer.The OBJECTIVE was to improve the results of treatment of patients with malignant neoplasms of the esophagus and esophagogastric junction, through the use of an integrated approach.METHODS AND MATERIALS. …”
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Combination of p-coumaric acid and lactoferrin ameliorates cognitive deficits through suppressing C/EBPβ/AEP pathway and modulating intestinal flora in APP/PS1 mice by Yan Zhou, Yitian Sun, Hui Guo, Yanzi Liang, Siyuan Zhu, Yu Sha, Zhongxiao Wan, Jiaying Xu, Jianrong Jiang, Liqiang Qin, Yunhong Li

“…Results showed that individual and combined treatments could ameliorate cognitive deficits to varying degrees, with stronger effects for combined intervention than for CA or Lf alone. Specifically, combined treatment was most effective in improving nesting ability and reducing amyloid β1-42 (Aβ1-42) deposition in mice. …”
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Efficacy of buffered and enteric-coated acetylsalicylic acid on platelet aggregation in patients with stable coronary artery disease and type 2 diabetes (CASCADE): rationale and de... by Zh. D. Kobalava, A. S. Pisaryuk, A. A. Filkova, E. S. Tukhsanboev, A. N. Amirova, A. D. Korneichuk, G. S. Pavlikov, L. R. Burkhanova, I. A. Meray, M. A. Panteleev, A. N. Sveshnikova

“…This single-center, non-interventional comparative study will randomly select 200 adult patients of both sexes with stable CAD and T2D who were routinely prescribed a gastro-soluble ASA (Cardiomagnyl 75 mg/day) or an enteric-soluble ASA (Aspirin® Cardio 100 mg/day or Thrombo ASS® 100 mg/day) before inclusion in the study. …”
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The MYH7 c.2770G > A (p.Glu924Lys) mutation exhibits phenotypic heterogeneity in hypertrophic cardiomyopathy (HCM) and restrictive cardiomyopathy (RCM): a case report by Yuanyuan Han, Haiyang Wang, Hongsheng Zhang, Manman Wang, Lijun Gan, Fanhua Meng

“…It is imperative that early genetic screening and clinical intervention are implemented to enhance the prognosis of affected families.…”
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Clinicopathological features of type 1 autoimmune pancreatitis without elevated serum IgG4 level by Yumiko Yamashita, Yasutaka Ishii, Keiji Hanada, Tamito Sasaki, Yoshifumi Fujimoto, Atsushi Yamaguchi, Ken Hirao, Masahiro Serikawa, Bunjiro Noma, Tomoyuki Minami, Akihito Okazaki, Masanobu Yukutake, Teruo Mouri, Yumiko Tatsukawa, Shinya Nakamura, Juri Ikemoto, Shiro Oka

“…Although the number of pathological findings was comparable, the rate of surgical intervention was significantly higher in the IgG4-negative group (P < 0.001). …”
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Evaluating Urban Mobility Resilience in Petrópolis Through a Multicriteria Approach by Alexandre Simas de Medeiros, Marcelino Aurélio Vieira da Silva, Marcus Hugo Sant’Anna Cardoso, Tálita Floriano Santos, Catalina Toro, Gonzalo Rojas, Vicente Aprigliano

“…Factors such as limited pedestrian access, insufficient motorized public transport coverage, and a high proportion of elderly residents emerged as significant constraints on urban resilience. Intervention strategies that promote active mobility, improve accessibility, and diversify transportation modes proved essential for strengthening local resilience. …”
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Investigating the association between household exposure to Anopheles stephensi and malaria in Sudan and Ethiopia: A case-control study protocol. by Temesgen Ashine, Yehenew Asmamaw Ebstie, Rayyan Ibrahim, Adrienne Epstein, John Bradley, Mujahid Nouredayem, Mikiyas G Michael, Amani Sidiahmed, Nigatu Negash, Abena Kochora, Jihad Eltaher Sulieman, Alison M Reynolds, Eba Alemayehu, Endalew Zemene, Adane Eyasu, Alemayehu Dagne, Elifaged Hailemeskel, Fatou Jaiteh, Dereje Geleta, Ephrem Lejore, David Weetman, Ahmed Mahmoud Hussien, Fadwa Saad, Gudissa Assefa, Hiwot Solomon, Abdelgadir Bashir, Fekadu Massebo, Koen Peeters, Delenasaw Yewhalaw, Hmooda Toto Kafy, Martin J Donnelly, Endalamaw Gadisa, Elfatih M Malik, Anne L Wilson

“…<h4>Conclusions</h4>Findings from this study will provide evidence of the relative importance of An. stephensi for malaria burden in urban African settings, shedding light on the need for future intervention planning and policy development.…”
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UBC9 overexpression promotes proliferation and metastasis in gastric cancer via ATF2 by QingShui Wang, ShengZhao Li, YiNing Xu, Yuluo Chen, Chao Xu, QiuYan He, Yan Ye, YiMin Huang, Yue Wu, KeJia Guo, YaJuan Wei, Yide Huang, Yan Liu, Qing Lin, Shanshan Wang, Feng Li, Minghan Huang, FangQin Xue, Yao Lin

“…Our findings establish UBC9 and ATF2 as promising prognostic biomarkers and potential therapeutic targets, suggesting that intervention in the UBC9-ATF2 axis may provide novel therapeutic strategies for inhibiting gastric cancer progression and improving patient outcomes.…”
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