A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care dataResearch in context by Olivia Murrin, Ninon Mounier, Bethany Voller, Linus Tata, Carlos Gallego-Moll, Albert Roso-Llorach, Lucía A. Carrasco-Ribelles, Chris Fox, Louise M. Allan, Ruby M. Woodward, Xiaoran Liang, Jose M. Valderas, Sara M. Khalid, Frank Dudbridge, Sally E. Lamb, Mary Mancini, Leon Farmer, Kate Boddy, Jack Bowden, David Melzer, Timothy M. Frayling, Jane A.H. Masoli, Luke C. Pilling, Concepción Violán, João Delgado

“…., abdominal aortic aneurysm and bladder cancer co-occurred in primary care but were not genetically correlated (Odds-Ratio = 2.23 [2.09:2.37], Rg = 0.04 [−0.20:0.28]) and schizophrenia and fibromyalgia were less likely to co-occur together in primary care but were positively genetically correlated (OR = 0.84 [0.75:0.94], Rg = 0.20 [0.11:0.29]). Interpretation: Most pairs of chronic conditions show evidence of shared genetics, and co-occurrence in primary care, suggesting shared mechanisms. …”
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Clinicians’ user experience with health information exchange technologies during simulated medication reconciliation by Himalaya Patel, April Savoy, Steven L. Sanchez, Morgan Traylor, Khoa A. Nguyen, Kenneth S. Boockvar, Vincent S. Fan, Emily R. Locke, Bryan Gibson, Amanda S. Mixon, Susan H. Byerly, David A. Haggstrom, Teresa M. Damush, Michael Weiner, Alissa L. Russ-Jara

“…To identify design-related barriers, we coded and interpreted usability and content problems that participants encountered. …”
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Evaluation of health care providers’ ability to identify patient-ventilator triggering asynchrony in intensive care unit: a translational observational study in China by Shengjun Liu, Zhangyi Zhao, Xiangyu Chen, Yi Chi, Siyi Yuan, Fuhong Cai, Zhangwei Song, Yue Ma, Huaiwu He, Longxiang Su, Yun Long

“…Entry test identified qualified professionals by matching concepts with its corresponding interpretations. Evaluation test assessed the ability in recognizing patient-ventilator asynchrony waveforms by matching asynchrony waveforms with corresponding concepts. …”
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Noninvasive respiratory support following extubation in critically ill adults with obesity: a systematic review and network meta-analysisResearch in context by Joris Pensier, Arthur Naudet-Lasserre, Clément Monet, Mathieu Capdevila, Yassir Aarab, Inès Lakbar, Gérald Chanques, Nicolas Molinari, Audrey De Jong, Samir Jaber

“…Compared to HFNC, both NIV (RR 0.31 [95% CI 0.13–0.74], NNT = 15 [95% CI 12–40]) and NIV + HFNC (RR 0.30 [95% CI 0.10–0.89], NNT = 15 [95% CI 11–90]) reduced 28-day mortality. Interpretation: The results suggest that compared to COT and HFNC, NIV alone or with HFNC reduces reintubation in critically ill patients with obesity after extubation. …”
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Sex differences in epigenetic ageing for older people living with HIVResearch in context by Carrie D. Johnston, Alina P.S. Pang, Eugenia L. Siegler, Charlene Thomas, Chelsie O. Burchett, Mia Crowley, Rochelle O'Brien, Lishomwa C. Ndhlovu, Marshall J. Glesby, Michael J. Corley

“…Risk of death was increased in females with PCPhenoAge acceleration over a 5-year timespan compared to men with PCPhenoAge acceleration (p = 0.03). Interpretation: These results highlight the importance of studying sex-specific differences in epigenetic ageing biomarkers for HIV-related geroscience research. …”
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Unraveling the immunological landscape and gut microbiome in sepsis: a comprehensive approach to diagnosis and prognosisResearch in context by Yali Luo, Jian Gao, Xinliang Su, Helian Li, Yingcen Li, Wenhao Qi, Xuling Han, Jingxuan Han, Yiran Zhao, Alin Zhang, Yan Zheng, Feng Qian, Hongyu He

“…A prognostic model based on the proportion of total lymphocytes, Helper T (Th) 17 cells, CD4+ effector memory T (TEM) cells, and Th1 cells in CD45+ leukocytes achieved robust outcome prediction (AUC = 0.906, 95% CI: 0.732–1.000), with further accuracy improvement when combined with clinical scores (AUC = 0.938, 95% CI: 0.796–1.000). Interpretation: NK cell subsets within innate immunity exhibit significant diagnostic value for sepsis, particularly when combined with B. salyersiae and CRP. …”
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Leveraging machine learning to uncover multi-pathogen infection dynamics across co-distributed frog families by Daniele L. F. Wiley, Kadie N. Omlor, Ariadna S. Torres López, Celina M. Eberle, Anna E. Savage, Matthew S. Atkinson, Lisa N. Barrow

“…Furthermore, sampling across broad taxonomic and geographic scales to evaluate these factors poses logistical challenges, and interpreting the roles of multiple potentially correlated variables is difficult with traditional statistical approaches. …”
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A Navier–Stokes-Informed Neural Network for Simulating the Flow Behavior of Flowable Cement Paste in 3D Concrete Printing by Tianjie Zhang, Donglei Wang, Yang Lu

“…NS equations are embedded into the NSINN to interpret the flow pattern in the 3D printing barrel. …”
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Diagnosis of tuberculosis in buffaloes in Argentina: intradermoreaction, compatible lesions and bacteriological culture by Emilia Irina Martínez, Fabiana Cipolini Galarza, Nolly María Monzón, Ana Gabriela Espasandin, José Luis Konrad, Elvira Falzoni, Soledad Barandiaran, Jimena Marfil, Marcela Martínez Vivot, Diana Elina Martínez

“…Because of the lack of standardized parameters for this species, two interpretation criteria were applied, a qualitative one (reactive, when any size increase was evident in the inoculation area/non-reactive), and the quantitative one following cattle-regulated criteria (positive reaction of more than 5mm, suspicious from 3 to 5mm and negative up to 3mm). …”
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Security and religion in democratizing Tunisia: re-enacting surveillance through religious narratives and gendered dynamics by Fabrizio Leonardo Cuccu, Alessandra Bonci

“…Analyzing the “everyday” or “mundane” dimension of security means focusing on the way in which security practices are interpreted, adapted, and/or negotiated by different individuals and groups through the lens of their lived experiences (Crawford and Hutchinson, 2016: 1190). …”
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Le mouvement étudiant et la question des langues en Algérie (1962-1965) : à propos d’un épisode méconnu de l’histoire de l’UGEMA-UNEA by Yassine Temlali

“…It looks more generally at the positions of this movement on the linguistic problem in Algeria in a context in which the promotion of the “national language”, Arabic, had to reckon with the first questioning of the Arabo-Islamic unanimity imposed by the need for unity against the French occupier.I suggest that the burial of these proposals in favour of Berber languages should be interpreted in the light of the cultural doctrine of the Algerian Communist Party (PCA), then dominant within the framework of the UGEMA, and its general attitude towards the “socialist” regime of Ahmed Ben Bella. …”
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Telehomecare Monitoring for Patients Receiving Anticancer Oral Therapy: Protocol for a Mixed Methods Evaluability Study by Dominique Tremblay, Thomas Joly-Mischlich, Annick Dufour, Marie-Claude Battista, Djamal Berbiche, José Côté, Marco Décelles, Catherine Forget, Brigitte Guérin, Manon Larivière, Frédéric Lemay, Manon Lemonde, Éric Maillet, Nathalie Moreau, Michel Pavic, Sara Soldera, Catherine Wilhelmy

“…Descriptive statistics and repeated measures using multiple linear mixed models and generalized estimating equations analyses will be undertaken alongside interpretive descriptive coding of qualitative data. …”
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Global assessment of leukemia care quality: insights from the quality of care index (QCI) from 1990 to 2021Research in context by Yuzhe Pan, Qian Liu, Nan Zhang, Shuang Peng, Xinqi Li, Fuling Zhou

“…Projections suggest a generally fluctuating upward trend in QCI for leukemia, reaching 79.58% by 2046. Interpretation: The QCI serves as an effective metric for evaluating the quality of leukemia care. …”
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Evaluating the Cellophane Production Supply Chain Using Multi-Criteria Decision-Making Approaches by َAhmad Jafarnejad, Amir Mohammad Khani

“…Design/methodology/approach: Interpretive Structural Modelling (ISM) has been used along with the Multi-Criteria Decision-Making (MCDM) approaches, supported by the Analytic Network Process (ANP). …”
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Identifying the Antecedents of Employee Perceptions of Human Resource Practices Using Signaling Theory by Aryan Gholipour, Mohammad Abooyee Ardakan, Neda Mohammad Esmaeili, Atiyeh Rasouli

“…For an organization to achieve its desired outcomes, it is essential that employees understand and interpret HR practices as they are intended by the organization. …”
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Consecutive prediction of adverse maternal outcomes of preeclampsia, using the PIERS-ML and fullPIERS models: A multicountry prospective observational study. by Guiyou Yang, Tünde Montgomery-Csobán, Wessel Ganzevoort, Sanne J Gordijn, Kimberley Kavanagh, Paul Murray, Laura A Magee, Henk Groen, Peter von Dadelszen

“…We recommend using the models for consecutive prediction with greater caution and interpreting predictions with increasing uncertainty as the pregnancy progresses. …”
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Internet-Based Dementia Prevention Intervention (DementiaRisk): Protocol for a Randomized Controlled Trial and Knowledge Translation by Anthony J Levinson, Stephanie Ayers, Sandra Clark, Rebekah Woodburn, Maureen Dobbins, Dante Duarte, Roland Grad, Nick Kates, Sharon Marr, Doug Oliver, Alexandra Papaioannou, Karen Saperson, Henry Siu, Gillian Strudwick, Richard Sztramko, Sarah Neil-Sztramko

“…Recruitment took place from March 28, 2023, to April 28, 2023, with the final participants completing the intervention by August 18, 2023. Analyses and interpretation of data are ongoing. ConclusionsDementiaRisk is a readily scalable, technology-enhanced solution for dementia prevention education. …”
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Loose cigarette purchase and adolescent smoking in Indonesia: a mixed-methods study by Vid Adrison, Dian Kusuma, Gea Melinda, Fariza Zahra Kamilah, Syifa Rizki Amelia, Sofwatun Nida

“…Finally, our study highlighted that only a few students in this study either had to show their identity card or were denied when purchasing loose cigarettes in informal retailers.Conclusion Our study demonstrates that students purchasing loose cigarettes is significantly associated with non-daily smoking, consuming five or fewer sticks per day, and lower addiction which could be interpreted as smokers in the experimental phase. They possessed a higher risk of becoming regular smokers. …”
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Episiotomies and obstetric anal sphincter injuries following a restrictive episiotomy policy in France: An analysis of the 2010, 2016, and 2021 National Perinatal Surveys. by Raphaele Houlbracq, Camille Le Ray, Béatrice Blondel, Nathalie Lelong, Anne Alice Chantry, Thomas Desplanches, ENP2021 Study Group

“…These results should be interpreted with caution given the low prevalence of OASI in some subgroups. …”
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Life course socioeconomic position and care dependency in later life: a longitudinal multicohort study from 17 countriesResearch in context by Ting Pan, Chenshuang Li, Ying Zhou

“…Furthermore, out of risk factors ranging from lifestyles, diseases to social connections, lack of social activities was found to be the primary contributor to socioeconomic inequalities in care dependency (explaining up to 66.63%), with corresponding interventions achieving universal health and economic benefits across countries. Interpretation: Changing socioeconomic status over the lifespan was associated with care dependency risk in later life. …”
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