Glucose-Lowering Agents Developed in the Last Two Decades and Their Perioperative Implications by Basavana Goudra, Geno J. Merli, Michael Green

“…For instance, Imeglimin, a variant of metformin available in Japan and India, Icodec, a once-weekly basal insulin formulation, and IcoSema, a once-weekly combination of Icodec plus semaglutide, are all being explored, although in their early stages or facing approval challenges.…”
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Anti-Glycemic and Anti-Hepatotoxic Effects of Mangosteen Vinegar Rind from Garcinia mangostana Against HFD/STZ-Induced Type II Diabetes in Mice by Karim Naymul, Jeenduang Nutjaree, Tangpong Jitbanjong

“…Increased hepatic glycogen content indicates improvement of insulin sensitivity. Moreover, oxidative damage markers were ameliorated in MVR- and glibenclamide-treated groups compared to the diabetic control group. …”
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Obesity Related Alterations in Plasma Cytokines and Metabolic Hormones in Chimpanzees by Pramod Nehete, Elizabeth R. Magden, Bharti Nehete, Patrick W. Hanley, Christian R. Abee

“…We also observed increased levels of metabolic hormones glucagon-like-peptide-1, glucagon, connecting peptide, insulin, pancreatic peptide YY3–36, and leptin in the plasma of overweight and obese chimpanzees. …”
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Assessment of the Primary and Intermediate School Staffs’ Knowledge, Attitude and Practice on Care of Children with Type 1 Diabetes at School, Al-Jouf, Saudi Arabia by Al Duraywish A A, Abdelsalam M Nail

“…Background: Children with diabetes type 1 (T1DM) need close monitoring for their blood glucose, food intake, insulin therapy and physical activity during school hours in order to guard against the development of acute and long-term complications. …”
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Comparison of Four Intrapartum Cardiotocography Classifications for Predicting Neonatal Acidemia at Birth by Nika Troha, Katja Razem, Ursa Luzovec, Miha Lucovnik

“…Exclusion criteria were suspected intrauterine growth restriction, oligohydramnios, polyhydramnios, pregestational or gestational insulin-dependent diabetes mellitus, and preeclampsia. …”
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Liver-innervating vagal sensory neurons are indispensable for the development of hepatic steatosis and anxiety-like behavior in diet-induced obese mice by Jiyeon Hwang, Sangbhin Lee, Junichi Okada, Li Liu, Jeffrey E. Pessin, Streamson C. Chua, Gary J. Schwartz, Young-Hwan Jo

“…Although males and females exhibit improved glucose homeostasis following disruption of liver-projecting vagal sensory neurons, only male mice display increased insulin sensitivity. Furthermore, the loss of liver-projecting vagal sensory neurons limits the progression of hepatic steatosis. …”
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Not Only Glycaemic But Also Other Metabolic Factors Affect T Regulatory Cell Counts and Proinflammatory Cytokine Levels in Women with Type 1 Diabetes by Katerina Stechova, Jana Sklenarova-Labikova, Tereza Kratzerova, Pavlina Pithova, Dominik Filipp

“…Total T-helper cell count was interconnected with BMI and glycaemia variability correlated with lipid spectra parameters, insulin dose, and vitamin D levels. These and other correlations revealed in this study provide broader insight into the association of various metabolic abnormalities with immune parameters that may impact T1D mothers or their developing child.…”
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The effect of high-sugar feeding on rodent metabolic phenotype: a systematic review and meta-analysis by Sophie Lucic Fisher, G. Jean Campbell, Alistair Senior, Kim Bell-Anderson

“…High-sugar feeding, with fructose in particular, altered liver phenotype; ALT (d = 1.08; 0.66, 1.5), triglyceride content (d = 0.52; 0.25, 0.78), cholesterol (d = 0.59; 0.16, 1.03) and liver mass (d = 0.93; 0.37, 1.48), and glucose tolerance; fasting glucose (d = 0.60; 0.18, 1.01) and fasting insulin (d = 0.42; 0.07, 0.77) but not body weight or energy intake. …”
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Plasma C1q/TNF-Related Protein-3 (CTRP-3) and High-Mobility Group Box-1 (HMGB-1) Concentrations in Subjects with Prediabetes and Type 2 Diabetes by Huili Wei, Hua Qu, Hang Wang, Huacong Deng

“…A multiple linear regression analysis showed both plasma CTRP-3 and HMGB-1 concentrations were independently associated with homeostasis model assessment for insulin resistance (HOMA-IR) and interleukin-6 (IL-6) (P<0.05 for all). …”
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The human‐specific noncoding RNA RP11‐424G14.1 functions at the intersection of sexually dimorphic pathways in inflammation, senescence, and metabolism by Kameron Kennicott, Yun Liang

“…IGFBP3 expression is dependent on insulin, and metabolomics analysis suggests that RP11‐424G14.1 and IGFBP3 regulate acrylcarnitine metabolism. …”
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Rs9939609 Variant of the Fat Mass and Obesity-Associated Gene and Trunk Obesity in Adolescents by Harald Mangge, Wilfried Renner, Gunter Almer, Daniel Weghuber, Reinhard Möller, Renate Horejsi

“…No associations were found with carotis communis intima media thickness, systolic, diastolic blood pressure, ultrasensitive C-reactive protein (US-CRP), homocystein, total cholesterol, triglycerides, HDL cholesterol, oxidized LDL, fasted glucose, insulin, HOMA-index, liver transaminases, uric acid, and adipokines like resistin, leptin, and adiponectin. …”
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School-Based Health Center Intervention Improves Body Mass Index in Overweight and Obese Adolescents by Alberta S. Kong, Andrew L. Sussman, Carolina Yahne, Betty J. Skipper, Mark R. Burge, Sally M. Davis

“…Measures included BMI percentile, waist circumference, insulin resistance by homeostasis model assessment (HOMA-IR), blood pressure, triglycerides, and HDL-C levels. …”
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The Role of Autophagy in the Pathogenesis of Diabetic Nephropathy by Kosuke Yamahara, Mako Yasuda, Shinji Kume, Daisuke Koya, Hiroshi Maegawa, Takashi Uzu

“…The multipronged drug approach targeting blood pressure and serum levels of glucose, insulin, and lipids fails to fully prevent the onset and progression of diabetic nephropathy. …”
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Caregiver’s Opinions on the Design of the Screens of a Future Gamified Mobile Application for Self-Management of Type 1 Diabetes in Children in Saudi Arabia by Demah M. Alsalman, Zahra Bu Ali, Zainab Alnosaier, Norah Alotaibi, Turki M. Alanzi

“…The key features of the screens were caring for a character; using a challenging friend; inclusion of points, level, and leaderboard as rewarding principles; use of reminders and notifications for doctor’s appointments, insulin injection times, blood glucose readings; and tips for improving medication adherence, increasing blood glucose readings, supporting physical activities, and adopting healthy eating habits. …”
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Treatment of Nonalcoholic Steatohepatitis in Adults: Present and Future by S. Gitto, G. Vitale, E. Villa, P. Andreone

“…Among the emerging treatments, telmisartan is particularly interesting as it seems to have an impact on insulin resistance, liver steatosis, inflammation, and fibrosis. …”
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Androgens and Adipose Tissue in Males: A Complex and Reciprocal Interplay by Caterina Mammi, Matilde Calanchini, Antonella Antelmi, Francesca Cinti, Giuseppe M. C. Rosano, Andrea Lenzi, Massimiliano Caprio, Andrea Fabbri

“…On the other hand, circulating levels of testosterone and estradiol deeply affect adipocyte proliferation, differentiation, and fat mass distribution, hereby controlling critical metabolic functions, such as food intake, insulin sensitivity, vascular reactivity, and immunity. …”
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The Use of Yoga in the Treatment of PCOS by Agnieszka Przesor Przezor, Natalia Medźwiedzka

“…PCOS is associated with a variety of health problems, including insulin resistance, obesity, hirsutism (excessive hair growth), and fertility problems. …”
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Dendrobium species regulate energy homeostasis in neurodegenerative diseases: a review by Feixuan Wang, Jingqiong Wan, Yangzhen Liao, Shangyu Liu, Yuan Wei, Zhen Ouyang

“…These dietary herbs and their derived compounds possess a variety of biological properties, such as suppression of oxidative stress and neuroinflammation, regulation of energy homeostasis mainly through improving brain mitochondria function, insulin signaling and lipid metabolism. Furthermore, they reduce neurotoxicity, alleviate brain injury and neuropathy, and prevent neurodegenerative conditions including stroke, Alzheimer's disease, Parkinson's disease, and Huntington's disease in humans and/or rodents. …”
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Chronostructure and circadian rhythms of the parameters of the coagulation system and neurohumoral regulatory systems determining diurnal profile of blood pressure by A.O. Ostapenko, Yu.O. Klitsunova, A.S. Kulbachuk, L.L. Vorontsova

“…All indexes of progressing coagulation and anticoagulation blood system has shown pronounced expressive shift of hypercoagulations in patients in the evening and at night. Fluctuations of insulin and glucose levels during 24 hours are also subject to circadian rhythm, i.e. maximal concentration is observed during the daytime, minimal one at night. …”
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Levels of Physical Activity in Nursing Students by Lázaro Dionisio Rojas Matsuda, Isaac Rodríguez Palacio, Katia Rodríguez Palacio, Ivis Espinoza Requesén, Ismaray Sacerio González, Carmen María Angulo Álvarez

“…<p><strong>Background:</strong> the benefits of physical exercise are well known and include a lower risk of cardiovascular diseases, obesity, insulin resistance and certain types of cancer such as colon and breast cancer. …”
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