-
1641
Risk factors for diabetic retinopathy: a case-control study
Published 2024-05-01“…Modifiable risk factors for DR include insulin, physical inactivity, dyslipidemia, alcoholism, and smoking. …”
Get full text
Article -
1642
СLINICAL CHARACTERISTICS OF CHILDREN AND ADOLESCENTS WITH METABOLIC SYNDROME IN KYIV
Published 2023-12-01“…Ambulatory blood pressure monitoring was performed using the ABM-04 device (Meditech, Hungary), and laboratory investigations (glucose, insulin, lipid profile) were conducted using the Cobas 6000 analyzer and test system (Roche Diagnostics). …”
Get full text
Article -
1643
Çocuk Hemşirelerinin Yüksek Riskli İlaçlarla İlgili Bilgi Düzeylerinin Belirlenmesi
Published 2024-08-01“…Hemşirelerin ilaçların hazırlanması işlem basamağında “insülin dozu hesaplanırken ‘mililitre’ yerine ‘ünite’ kullanılmalıdır.” ifadesine %96,9 ile ilaçların uygulanması işlem basamağında ise “Kalsiyum glukonat intramuskuler uygulandığında ciddi nekrozlara neden olabilir.” ifadesine %83,1 ile en yüksek cevabı verdikleri görülmüştür. …”
Get full text
Article -
1644
Innovative immunotherapies and emerging treatments in type 1 diabetes management
Published 2025-01-01“…Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease characterized by the selective destruction of pancreatic insulin-producing beta cells, primarily mediated by CD4+ and CD8+ T cells. …”
Get full text
Article -
1645
Recent advances in nutritional metabolism studies on SARS-CoV-2 infection
Published 2025-03-01“…SARS-CoV-2 infection leads to insulin resistance and increased glycolysis, reducing glucose utilization and shifting metabolism to use fat as an energy source. …”
Get full text
Article -
1646
Inhibitory effects of cashew Anacardium occidentale L. kernel, apple, and shell extracts on lipid accumulation and adipogenesis in 3T3-L1 adipocytes
Published 2025-01-01“…Abstract Obesity, a major risk factor for various metabolic diseases, often results in dysfunctional white adipose tissue and altered adipogenesis leading to ectopic fat accumulation, inflammation, and insulin resistance. On the other hand, cashew (Anacardium occidentale L.) nut worldwide consumption and production is increasing steadily, which augments the mass of byproducts to be discarded. …”
Get full text
Article -
1647
Exosomal miR-543 Inhibits the Proliferation of Ovarian Cancer by Targeting IGF2
Published 2022-01-01“…The expression of miR-543 was significantly decreased in exosomes derived from OvCa cell lines, patient serum, and OvCa tissues, while the mRNA levels of insulin-like growth factor 2 (IGF2) were increased. …”
Get full text
Article -
1648
Do Anabolic Androgenic Steroids Really Cause Harm? A Comprehensive Examination of Adverse Effects
Published 2025-02-01“…These processes are mediated through the modulation of insulin-like growth factor-1 (IGF-1) and the inhibition of glucocorticoid-induced catabolism. …”
Get full text
Article -
1649
Extracellular vesicle-mediated approaches for the diagnosis and therapy of MASLD: current advances and future prospective
Published 2025-01-01“…Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) is an asymptomatic, multifaceted condition often associated with various risk factors, including fatigue, obesity, insulin resistance, metabolic syndrome, and sleep apnea. …”
Get full text
Article -
1650
Diabetes medication prescribing trends based on provider type and location in the United States
Published 2025-01-01“…Nurse practitioners were more likely to prescribe newer diabetes medications, while physician assistants frequently prescribed basal insulin. Patients in non-metropolitan statistical areas were more often prescribed older medications, whereas those in the West were less likely to receive older medications. …”
Get full text
Article -
1651
Substituted piperazine conjugated to quinoline-thiosemicarbazide as potent α-glucosidase inhibitors to target hyperglycemia
Published 2025-01-01“…Abstract Diabetes mellitus, particularly type 2 diabetes, is a growing global health challenge characterized by chronic hyperglycemia due to insulin resistance. One therapeutic approach to managing this condition is the inhibition of α-glucosidase, an enzyme involved in carbohydrate digestion, to reduce postprandial blood glucose levels. …”
Get full text
Article -
1652
Abruptio Placentae Caused by Hypertriglyceridemia-Induced Acute Pancreatitis during Pregnancy: Case Report and Literature Review
Published 2018-01-01“…Immediate cesarean section was performed and it was observed that blood sample revealed a milky turbid serum. Insulin, heparin, and supportive treatment were started. …”
Get full text
Article -
1653
Hyperuricemia-induced complications: dysfunctional macrophages serve as a potential bridge
Published 2025-01-01“…Characterized by elevated levels of UA, HUA has become an independent risk factor for gout, chronic kidney disease, insulin resistance, cardiovascular disease, nonalcoholic fatty liver disease, etc. …”
Get full text
Article -
1654
Cardiac-Restricted IGF-1Ea Overexpression Reduces the Early Accumulation of Inflammatory Myeloid Cells and Mediates Expression of Extracellular Matrix Remodelling Genes after Myoca...
Published 2015-01-01“…Our previous studies have shown that constitutive expression of a locally acting insulin-like growth factor-1 Ea (IGF-1Ea) propeptide promotes functional restoration after cardiac injury associated with decreased scar formation. …”
Get full text
Article -
1655
Sheehan Syndrome Presenting with Psychotic Manifestations Mimicking Schizophrenia in a Young Female: A Case Report and Review of the Literature
Published 2020-01-01“…She had poor cortisol and growth hormone response to the insulin tolerance test. MRI-pituitary showed empty sella. …”
Get full text
Article -
1656
Luteolin ameliorates rat model of metabolic syndrome-induced cardiac injury by apoptosis suppression and autophagy promotion via NR4A2/p53 regulation
Published 2025-01-01“…The animal’s weight, blood pressure, lipid profile, tolerance to glucose and insulin, and cardiac histopathology were evaluated. …”
Get full text
Article -
1657
Inflammatory Role of Toll-Like Receptors in Human and Murine Adipose Tissue
Published 2010-01-01“…It was recently demonstrated that TLR4 activation via dietary lipids triggers inflammatory pathway and alters insulin responsiveness in the fat tissue during obesity. …”
Get full text
Article -
1658
The Role of HMGB1 in the Pathogenesis of Type 2 Diabetes
Published 2016-01-01“…Importantly, we will summarize and renovate the role of HMGB1 and HMGB1-mediated inflammatory pathways in adipose tissue inflammation, insulin resistance, and islet dysfunction. Future Directions. …”
Get full text
Article -
1659
Stable Metabolic Control but Increased Demand for Professional Support in Children with Type 1 Diabetes in the Past Ten Years in Bern/Switzerland: A Quality Control Study
Published 2022-01-01“…Compared to historical data, stable HbA1c levels appeared with a doubled proportion of individuals using insulin pumps. Metabolic control was worse with a longer duration of diabetes and younger age at diagnosis but better when parents came from a Western European country. …”
Get full text
Article -
1660
IGF-1 Restores Visual Cortex Plasticity in Adult Life by Reducing Local GABA Levels
Published 2012-01-01“…Recent studies have challenged this dogma providing evidence that both pharmacological treatments and paradigms based on the manipulation of environmental stimulation levels can be successfully employed as strategies for enhancing plasticity in the adult nervous system. Insulin-like growth factor 1 (IGF-1) is a peptide implicated in prenatal and postnatal phases of brain development such as neurogenesis, neuronal differentiation, synaptogenesis, and experience-dependent plasticity. …”
Get full text
Article