Calcium Signaling in the Ventricular Myocardium of the Goto-Kakizaki Type 2 Diabetic Rat by L. Al Kury, M. Smail, M. A. Qureshi, V. Sydorenko, A. Shmygol, M. Oz, J. Singh, F. C. Howarth

“…The GK rat is a widely used nonobese, nonhypertensive genetic model of T2DM which is characterized by insulin resistance, elevated blood glucose, alterations in blood lipid profile, and cardiac dysfunction.…”
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The Possible Potential Therapeutic Targets for Drug Induced Gingival Overgrowth by Tamilselvan Subramani, Vidhya Rathnavelu, Noorjahan Banu Alitheen

“…Proteins such as transforming growth factor (TGF), endothelin-1 (ET-1), angiotensin II (Ang II), connective tissue growth factor (CCN2/CTGF), insulin-like growth factor (IGF), and platelet-derived growth factor (PDGF) appear to act in a network that contributes to the development of gingival fibrosis. …”
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Diabetes mellitus health care management by Susan Miriam Oblitas Guerrero, Flor Delicia Heredia Llatas, Sttefany Naghely Santamaría Oblitas, Roberto Pelayo Mosqueira Moreno

“…Differences were also found in obtaining adequate, regular and timely medication, in the availability of insulin and medical supplies, and in the daily control of blood glucose. …”
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Thiazolidinediones and Edema: Recent Advances in the Pathogenesis of Thiazolidinediones-Induced Renal Sodium Retention by Shoko Horita, Motonobu Nakamura, Nobuhiko Satoh, Masashi Suzuki, George Seki

“…Thiazolidinediones (TZDs) are one of the major classes of antidiabetic drugs that are used widely. TZDs improve insulin resistance by activating peroxisome proliferator-activated receptor gamma (PPARγ) and ameliorate diabetic and other nephropathies, at least, in experimental animals. …”
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FXR Mediates Adenylyl Cyclase 8 Expression in Pancreatic β-Cells by Xiangchen Kong, Bingfeng Li, Yushen Deng, Xiaosong Ma

“…Adenylyl cyclase 8 (ADCY8) and Farnesoid X Receptor (FXR) have been identified in pancreatic β-cells and play important roles in insulin secretion. But the mechanisms underlying with respect to the regulation of ADCY8 expression in β-cells, particularly whether FXR is involved, remain unexplored. …”
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Sustained Liver Glucose Release in Response to Adrenaline Can Improve Hypoglycaemic Episodes in Rats under Food Restriction Subjected to Acute Exercise by Lucas K. R. Babata, Maria M. D. Pedrosa, Rosângela F. Garcia, Márcia V. Peicher, Vilma Aparecida Ferreira de Godoi

“…The blood glucose profile during an episode of insulin-induced hypoglycaemia in exercised and nonexercised male Wistar control (GC) and food-restricted (GR, 50%) rats and liver glucose release stimulated by glucagon and adrenaline were investigated. …”
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Diet modification and metformin have a beneficial effect in a fly model of obesity and mucormycosis. by Fazal Shirazi, Dimitrios Farmakiotis, Yuanqing Yan, Nathaniel Albert, Kim-Anh Do, Dimitrios P Kontoyiannis

“…Fly models of obesity bear intriguing similarities to the pathophysiology of insulin resistance and diabetes in humans, and can provide new insights into the pathogenesis and treatment of infections in obese and diabetic patients.…”
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Effect of Vitamins A, C, and E Supplementation in the Treatment of Metabolic Syndrome in Albino Rats by L. S. Bilbis, S. A. Muhammad, Y. Saidu, Y. Adamu

“…Percentage weight gain indicated significant positive correlation with triglyceride, insulin resistance, and malondialdehyde while total antioxidant status and nitric oxide showed significant negative correlation. …”
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Glycaemic Control after Metformin Discontinuation in Diabetic Patients with a Declining Renal Function by Theresa Leyco, Davin Ryanputra, Ray Peh, Alexphil Ponce, Chin Meng Khoo

“…Upon metformin discontinuation, the majority of patients had their diabetes medication uptitrated (in particular insulin or sulphonylurea). Patients with an improved glycaemia at 6-month follow-up had further declined in eGFR compared to patients with worsened glycaemia. 17% of the study patients experienced hypoglycaemia. …”
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Participation of COX2/mPGES1/PGE2 in mouse and human endometrial stromal decidualization by Peng-Chao Wang, Jie Liu, Yue-Fang Liu, Yang Wu, Lin-Li Xue, Zhen-Shan Yang

“…PGE2-mediated upregulation of insulin growth factor binding protein 1 (IGFBP1) was significantly inhibited by Valdecoxib and MK886. …”
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Serum 25(OH)D Levels Modify the Association between Triglyceride and IR: A Cross-Sectional Study by Rongpeng Gong, Xin Tang, Ziying Jiang, Gang Luo, Chaofan Dong, Xiuxia Han

“…This study demonstrates that triglyceride levels are significantly associated with insulin in the US adult population and can be used as a predictor of IR. …”
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Anti-Thyroid Peroxidase Antibodies and Male Gender Are Associated with Diabetes Occurrence in Patients with Beta-Thalassemia Major by Giovanni M. Pes, Francesco Tolu, Maria P. Dore

“…In patients with β-T major a progressive damage of insulin-producing cells due to secondary hemosiderosis appears to be the most reasonable mechanism associated with glucose metabolism disorders. …”
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A Randomized Controlled Trial in Obese Adults with Polycystic Ovarian Syndrome: Examining the Impact of Short-term Integrated Naturopathy and Yoga Interventions on Testosterone, Ox... by Balakrishna Shetty, Geetha Balakrishna Shetty, H. L. Nanjeshgowda, Prashanth Shetty

“…Pathology manifests as the changes in reproductive functions, encompassing disorders such as hyperandrogenism, irregular menstrual cycles, and insulin resistance with oxidative stress. We investigated the effect of naturopathy and yoga interventions on oxidative stress and androgens with metabolic parameters in patients with PCOS. …”
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Integrating 16S rDNA and metabolomics to uncover the therapeutic mechanism of electroacupuncture in type 2 diabetic rats by Zhang Yue, Wang Xiang, Deng Duping, Gong Yuanyuan, Chen Xuanyi, Li Juan, Li Juan, Hong Xiaojuan

“…EA also reduced FBG, the area under the curve of the OGTT, FINS, and homeostasis model assessment of insulin resistance (HOMA-IR) in T2DM rats (p < 0.05). …”
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Impact of remnant cholesterol on short-term and long-term prognosis in patients with prediabetes or diabetes undergoing coronary artery bypass grafting: a large-scale cohort study by Zhongchen Li, Chunyu Yu, Heng Zhang, Runze Chen, Yan Zhao, Zhe Zheng

“…Subgroup analysis indicated that this risk was more pronounced in insulin-treated patients. Conclusions Remnant-C is associated with AKI and MACCEs in patients with diabetes or prediabetes undergoing CABG. …”
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The HFA‐PEFF score identifies ‘early‐HFpEF’ phenogroups associated with distinct biomarker profiles by Michiel T.H.M. Henkens, Anne‐Mar vanOmmen, Sharon Remmelzwaal, Gideon B. Valstar, Ping Wang, Job A.J. Verdonschot, Mark R. Hazebroek, Leonard Hofstra, Vanessa P.M. vanEmpel, Joline W.J. Beulens, Hester M. denRuijter, Stephane R.B. Heymans

“…The top eight biomarkers—N‐terminal prohormone brain natriuretic peptide, growth differentiation factor‐15, matrix metalloproteinase‐2, osteoprotegerin, tissue inhibitor of metalloproteinase‐4, chitinase‐3‐like protein 1, insulin‐like growth factor‐binding protein 2, and insulin‐like growth factor‐binding protein 7—are mainly involved in inflammation and extracellular matrix remodelling, which are currently proposed key processes in HFpEF pathophysiology. …”
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Effect of the gut core microbiota Cetobacterium on the growth, physiology, and nutritional metabolism of Nile tilapia (Oreochromis niloticus) by Miao Wang, Chenglin Tang, Ziyue Zhang, Zijian Fan, Lijin Jiang, Zhigang Liu, Jianmeng Cao, Zhang Wang, Maixin Lu, Mengmeng Yi, Xiaoli Ke

“…Analysis of growth indices, serum insulin, glucose and triglyceride (TG) levels, carbohydrate content in the gut, and amino acid levels in the serum were conducted. …”
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Generation of Transplantable Beta Cells for Patient-Specific Cell Therapy by Xiaojie Wang, Daniel L. Metzger, Mark Meloche, Jianqiang Hao, Ziliang Ao, Garth L. Warnock

“…Therefore, alternative sources of insulin-producing cells and isletfriendly immunosuppression are required to increase the efficiency and safety of this procedure. …”
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Using nonlinear auto-regressive with exogenous input neural network (NNARX) in blood glucose prediction by Fayrouz Allam

“…The predicted BG can be used for glycemia management in the form of early hypoglycemic/hyperglycemic alarms or adjusting insulin injections. Recent developments in continuous glucose monitoring (CGM) devices open new opportunities for glycemia management of diabetic patients. …”
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Chronic Caloric Restriction and Exercise Improve Metabolic Conditions of Dietary-Induced Obese Mice in Autophagy Correlated Manner without Involving AMPK by Mingxia Cui, Han Yu, Jinli Wang, Junjie Gao, Ji Li

“…Then their metabolic conditions were assessed by measuring serum glucose and insulin, serum lipids, and liver function. AMPK phosphorylation and autophagy activity were detected by western blotting. …”
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