Liver Damage in Type 1 Diabetes Mellitus by A. O. Bueverov, A. V. Zilov

“…Its important link is a likely inherited non-physiological insulin supply to the tissue, especially at marked glycaemic fluctuations. …”
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Metformin in the treatment of colorectal cancer and neuroendocrine tumours by Karolina Daniłowska, Natalia Picheta, Barbara I. Krupska, Anna Rudzińska, Oliwia Burdan, Katarzyna Szklener

“…The biguanide works by inhibiting the mammalian target of rapamycin pathway, activating 5’AMP activated protein kinase, and reducing insulin-like growth factor 1. In studies conducted on human cells and xenografts, the drug has shown its positive effects in combating these tumors by reducing proliferation, slowing the growth of cancer cells, and inhibiting metastasis. …”
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Mesenchymal Stem Cells (MSCs): A Novel Therapy for Type 2 Diabetes by Shuang Gao, Yuanyuan Zhang, Kaini Liang, Ran Bi, Yanan Du

“…Potential mechanisms of MSC-based intervention on multiple pathological processes of T2DM, such as β-cell exhaustion, hepatic dysfunction, insulin resistance, and systemic inflammation, are also delineated. …”
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SIRT1 Regulates Cognitive Performance and Ability of Learning and Memory in Diabetic and Nondiabetic Models by Yue Cao, Zi Yan, Tong Zhou, Guixia Wang

“…SIRT1, as one of the modulators in insulin resistance, is indispensable for learning and memory. …”
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Sirtuins and Their Implications in the Physiopathology of Gestational Diabetes Mellitus by Katarzyna Zgutka, Marta Tkacz, Marta Grabowska, Wioletta Mikołajek-Bedner, Maciej Tarnowski

“…Chronic low-grade inflammation, oxidative stress, and insulin resistance are central features of pregnancies complicated by GDM. …”
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Harmony in Health: A Narrative Review Exploring the Interplay of Mind, Body, and Diabetes with a Special Emphasis on Emotional Stress by Jayakrishnan Balakrishnanpillai, Jothydev Kesavadev, Banshi Saboo

“…Drawing on a wealth of research spanning the intersection of psychology, physiology, and diabetes care, the review delves into the multifaceted ways, in which emotional stress can influence glycemic control, insulin sensitivity, and overall well-being. It extends beyond traditional biomedical perspectives to encompass psychosocial dimensions and emphasizes the reciprocal relationship between emotional well-being and diabetes outcomes. …”
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Treatment adherence of diabetes mellitus patients: Is it affected by demographic and patient-related factors? A literature review by Paraskevi Theofilou

“…Based on these studies, patients with diabetes mellitus show quite low adherence to insulin therapy. The perceptions about the disease of diabetes, the availability of drugs, the diabetes education provided, perceptions of medication, current patients’ employment, younger age, educational level, nationality, HbA1c levels, abstinence from alcohol, presence of peripheral vascular disease, income, keeping their appointments in primary health care, and the religious beliefs about healing and healing practices are important factors influencing the compliance of patients with diabetes in their treatment. …”
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Cytokines in the Progression of Pancreatic β-Cell Dysfunction by Chunjiong Wang, Youfei Guan, Jichun Yang

“…The imbalance in deleterious and protective cytokines plays pivotal roles in the development and progression of pancreatic β-cell dysfunction under insulin-resistant conditions.…”
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Sirtuins and mechanisms of diabetic lung damage: a scientific discussion. A review by Sergei L. Babak, Marina V. Gorbunova, Andrey G. Malyavin, Vladislav S. Borovitsky

“…It is known that sirtuins regulate a number of physiological processes and affect obesity, insulin resistance, type 2 DM, heart disease and aging. …”
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Posttransplant Metabolic Syndrome by M. Shadab Siddiqui, Richard K. Sterling

“…Metabolic syndrome (MS) is a cluster of metabolic derangements associated with insulin resistance and an increased risk of cardiovascular mortality. …”
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Bioactive Components and Health Benefits of Saskatoon Berry by Lunan Zhao, Fei Huang, Amy Leung Hui, Garry X. Shen

“…In response to the recent rise in numbers of diabetes patients, many treatments have been developed; but currently, oral antihyperglycemic agents and insulin are still the main clinical treatments. Since current drugs have limitations and harmful side effects, research in alternative treatments has been sought. …”
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DKA with Severe Hypertriglyceridemia and Cerebral Edema in an Adolescent Boy: A Case Study and Review of the Literature by Tansit Saengkaew, Taninee Sahakitrungruang, Suttipong Wacharasindhu, Vichit Supornsilchai

“…Normal saline was carefully given and regular insulin was titrated according to blood sugar levels. …”
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Stress in Obesity and Associated Metabolic and Cardiovascular Disorders by Paul Holvoet

“…This syndrome is a common and complex disorder combining obesity, dyslipidemia, hypertension, and insulin resistance. It is associated with high atherosclerotic cardiovascular risk, which can only partially be explained by its components. …”
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Role of Quercetin in Diabetic Cardiomyopathy by Nor Hidayah Mustafa, Hawa Nordin Siti, Yusof Kamisah

“…Secondary metabolites, including quercetin, have shown promising effects in mitigating the progression of diabetic cardiomyopathy by targeting multiple pathological mechanisms, including impaired insulin signaling, glucotoxicity, lipotoxicity, oxidative stress, inflammation, fibrosis, apoptosis, autophagy, mitochondrial dysfunction, cardiac stiffness, and disrupted calcium handling. …”
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Putative Factors That May Modulate the Effect of Exercise on Liver Fat: Insights from Animal Studies by Faidon Magkos

“…An increase in intrahepatic triglyceride (IHTG) content is the hallmark of nonalcoholic fatty liver disease (NAFLD) and is strongly associated with insulin resistance and dyslipidemia. Although regular aerobic exercise improves metabolic function, its role in regulating fat accumulation in the liver is incompletely understood, and human data are scarce. …”
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Predictors of developing severe COVID-19 among hospitalized patients: a retrospective study by Hussain Abduljaleel Alkhalifa, Ehab Darwish, Zaenb Alsalman, Aman Alfaraj, Abdullah Alkhars, Fatimah Alkhalifa, Mohammed Algaraash, Ahmed Mohammed Elshebiny, Emad Alkhoufi, Khaled Mohamed Amin Elzorkany

“…The univariate analysis shows that having diabetes, having high severe acute respiratory infection chest X-ray scores, old age, prolong hospitalization, high potassium and lactate dehydrogenase, as well as using insulin, heparin, corticosteroids, favipiravir or azithromycin were all statistically significant associated with severe COVID-19. …”
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Gambaran Kadar Gula Darah pada Mahasiswa Fakultas Kedokteran Universitas Andalas yang Memiliki Berat Badan Berlebih dan Obesitas by Putri Auliya, Fadil Oenzil, Zelly Dia Dia Rofinda

“…<strong>Abstrak</strong><div class="WordSection2"><p class="NoSpacing">Obesitas dan berat badan berlebih merupakan faktor predisposisi terhadap resistensi insulin yang dapat menyebabkan peningkatan kadar gula darah sehingga terjadi diabetes mellitus tipe 2. …”
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A Multicenter Retrospective Survey regarding Diabetic Ketoacidosis Management in Italian Children with Type 1 Diabetes by Stefano Zucchini, Andrea E. Scaramuzza, Riccardo Bonfanti, Pietro Buono, Francesca Cardella, Vittoria Cauvin, Valentino Cherubini, Giovanni Chiari, Giuseppe d’Annunzio, Anna Paola Frongia, Dario Iafusco, Giulio Maltoni, Ippolita Patrizia Patera, Sonia Toni, Stefano Tumini, Ivana Rabbone, Diabetes Study Group of the Italian Society for Pediatric Endocrinology and Diabetology (ISPED)

“…Bicarbonate was quite never been used. Insulin was infused starting from third hour at the rate of 0.05–0.1 U/kg/h in 72% of centers. …”
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Recombinant Lactococcus lactis Carrying IL-4 and IL-10 Coding Vectors Protects against Type 1 Diabetes in NOD Mice and Attenuates Insulitis in the STZ-Induced Model by Tatiane M. Preisser, Vanessa P. da Cunha, Mariana P. Santana, Vanessa B. Pereira, Denise C. Cara, Bianca M. Souza, Anderson Miyoshi

“…Type 1 diabetes (T1D) is an autoimmune disease that culminates in beta cell destruction in the pancreas and, subsequently, deficiency in insulin production. Cytokines play a crucial role in the development of diabetes, orchestrating the recruitment and action of immune cells, to not only destroy insulin-producing cells but also preserve them. …”
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Real world pharmacovigilance assessment of drug related macular degeneration risks by Xiaodong Chen, Shinan Wu, Shaopan Wang, Chaofeng Yu, Zihan Guo, Shiya Huang, Peixin Cai, Yanliang Miao, Shiying Li, Qian Chen

“…Among these, 42 drugs were linked to significant risks, including treatments for breast cancer (tamoxifen, raloxifene, anastrozole, letrozole) and diabetes (insulin lispro, insulin human). The BCPNN algorithm revealed that 45.2% (19/42) of these drugs had the strongest associations with macular degeneration, with pentosan polysulfate sodium, travoprost, and tolterodine being the highest-risk drugs. …”
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