Dietary and plasma atherogenic and thrombogenic indices and cardiometabolic risk factors among overweight and individuals with obesity by Reyhaneh Mokhtari, Mahdieh Abbasalizad Farhangi

“…Additionally, biochemical parameters, including serum total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), fasting serum glucose (FSG), and insulin levels, were measured using enzymatic methods. …”
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Meta-Analysis of the Effect of Resistance Exercise Prescription on Glucose and Lipid Metabolism in Overweight and Obese Adults by SUN Yuxin, GUO Xiaoyuan, CHEN Shi, PAN Hui, ZHU Huijuan

“…The literature was screened by 2 researchers according to inclusion and exclusion criteria and relevant data were extracted.Meta-analysis of included literature was performed using RevMan 5.3 software, and publication bias was assessed using funnel plots.ResultsA total of 17 papers and 700 study subjects were included, with 351 cases in the test group, and 349 cases in the control group.Meta-analysis results showed that compared with the control group, the glycosylated hemoglobin of the test group with resistance exercise[SMD (95% CI) =-0.30(-0.53--0.07), P=0.010], fasting blood glucose[SMD (95% CI)=-0.58(-0.90--0.26), P < 0.001], insulin resistance index[SMD (95% CI) =-0.90 (-1.42--0.38), P < 0.001], and low-density lipoprotein cholesterol (LDL-C)[SMD (95% CI) =-0.28 (-0.53--0.04), P=0.020] levels were reduced.Subgroup analysis showed that the glucose metabolism levels of the test group with only resistance exercise and a combination of resistance-anaerobic exercise were significantly lower than those of the control group(both P < 0.05).The heterogeneity of the effect of resistance exercise on glucose metabolism in Asian populations(I2=57%) was smaller than that in Caucasion(I2=76%) and other populations(I2=94%), and the level of decrease in glucose metabolism indexes was significant[SMD(95% CI)=-1.15(-1.73--0.57), P < 0.001].ConclusionResistance exercise can significantly reduce the level of glycolipid metabolism indexes in overweight or obese people.…”
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The Association between Resolvin D1 Levels and Gestational Diabetes Mellitus: Implications for Perinatal Outcomes by Zeynep Seyhanli, Burak Bayraktar, Mevlut Bucak, Gulsan Karabay, Betul Tokgoz Cakir, Can Ozan Ulusoy, Gizem Aktemur, Selver Ozge Sefik, Serap Topkara Sucu, Sevki Celen, Ali Turhan Caglar

“…Additionally, the GDM group was categorized based on management approach into 21 women managed with diet alone and 23 women requiring insulin therapy. Maternal plasma Resolvin D1 levels and maternal-neonatal outcomes were then compared between groups. …”
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Utility of Visceral Adiposity Index and Lipid Accumulation Products to Define Metabolically-Unhealthy Polycystic Ovary Syndrome in Asian Indian Women - A Cross Sectional Study by R. A. Shreenidhi, Reeta Mahey, Monika Rajput, Rohitha Cheluvaraju, Ashish D. Upadhyay, Jai Bhagwan Sharma, Garima Kachhawa, Neerja Bhatla

“…Background: Polycystic ovary syndrome (PCOS) women are at risk of developing diabetes, cardiovascular disease and metabolic syndrome (MetS) due to insulin resistance (IR) and hyperandrogenism (HA). …”
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Phytochemical study and evaluation of the antidiabetic and antihyperglycemic activities of the fruit extracts of Physalis peruviana L. (Solanaceae) by Damien S.T. Tshibangu, Fortune S. Kavugho, Carlos N. Kabengele, Adrien T. Masunda, Gédéon N. Bongo, Giresse N. Kasiama, Domaine T. Mwanangombo, Clément L. Inkoto, Clément M. Mbadiko, Benjamin Z. Gbolo, Désiré M. Musuyu, Dorothée D. Tshilanda, Jean Paul K.N. Ngbolua, Pius T. Mpiana

“…This inhibition was confirmed by molecular docking analyzes by interacting the molecules of the studied plant with two receptors, alpha-glucosidase (PDB id: 3WY1) and the kinase domain of the 5HHW insulin receptor.These experimental results lend credibility to the use of this species in traditional Congolese medicine to treat type 2 diabetes.…”
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Network pharmacology and experimental verification to investigate the mechanism of isoliquiritigenin for the treatment of Alzheimer’s disease by Waimao Gao, Guang Yang, Xinjuan Liu, Kaifan Hu, Jie Pan, Xingyu Wang, Yan Zhao, Ying Xu

“…The PPI network manifested 7 key targets including albumin (ALB), epidermal growth factor receptor (EGFR), solute carrier family 2 member 1 (SLC2A1), insulin-like growth factor 1 (IGF1), mitogen-activated protein kinase 1 (MAPK1), peroxisome proliferator activated receptor alpha (PPARA) and peroxisome proliferator activated receptor gamma (PPAR-γ, PPARG). …”
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The relationship between oxLDL, sLOX-1, PCSK9 and carotid intima-media thickness in patients with prediabetes and type 2 diabetes by Zeki Dogan, Abdulhalim Senyigit, Sinem Durmus, Canan Duvarcı, Remise Gelişgen, Hafize Uzun, Omur Tabak

“…Homeostasis model assessment for insulin resistance (HOMA-IR) was also calculated. …”
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Prescription pattern, glycemic control status, and predictors of poor glycemic control among diabetic patients with comorbid chronic kidney disease in Ethiopia: a facility-based cr... by Oumer Sada Muhammed, Minimize Hassen, Samuel Mamusha

“…Only 4.4% achieved good glycemic control (glycated hemoglobin [HbA1c] < 7%), while 95.6% had poor glycemic control (HbA1c ≥ 7%). Insulin, metformin, and sodium glucose cotransporter-2 (SGLT-2) inhibitors were the most frequently prescribed anti-diabetic drug classes which accounted for 80.2%, 59.1%, and 41.4%, respectively. …”
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The Role of Physical Activity in Pregnancy: Impact on Preeclampsia, Gestational Diabetes Mellitus, and Labor Outcomes by Paulina Woźniak, Ewa Wietrzykowska, Wiktoria Gajek-Flanczewska, Sebastian Flanczewski, Małgorzata Wirkijowska, Jakub Wirkijowski, Katarzyna Wójtowicz, Agata Walczak, Dominika Sobolewska, Katarzyna Michalczyk-Fraszka, Martyna Śliwińska, Anna Podraza

“…Additionally, women with GDM treated with insulin who regularly participate in PA require a lower dosage compared to those leading sedentary lifestyles. …”
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Predictors of biochemical and structural response to medical therapy in patients with active acromegaly following surgery: a real-world perspective by Maryam Rafieemanesh, Manizhe Ataee Kachuee, Ali Zare Mehrjardi, Alireza Khajavi, Mohammad Ghorbani, Mohammad Reza Mohajeri-Tehrani, Nahid Hashemi-Madani, Mohammad E. Khamseh

“…Biochemical outcomes were defined as the tight biochemical response (TBR; normal insulin-like growth factor-1(IGF-1)) and biochemical control (BC; IGF-1 ≤ 1.2 upper limit of normal (ULN)). …”
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Association of baseline and trajectory of triglyceride-glucose index with the incidence of cardiovascular autonomic neuropathy in type 2 diabetes mellitus by Qiong Huang, Wenbin Nan, Baimei He, Zhenhua Xing, Zhenyu Peng

“…The triglyceride-glucose (TyG) index represents a precise insulin resistance indicator. However, the influence of baseline and prolonged TyG index patterns on CAN risk in type 2 diabetes remains unclear. …”
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Pengaruh Pemberian Kefir Madu terhadap Profil Lipid Tikus Galur Sprague Dawley Sindroma Metabolik by Ibnu Malkan Bakhrul Ilmi, Angga Hardiansyah, Nikmatul Luailiya, Putri Aria Avrilian, Avliya Quratul Marjan, Dina Sugiyanti, Nur Hayati

“…Latar Belakang: Sindroma metabolik didefinisikan sebagai sekelompok gejala perubahan metabolik tubuh yang terjadi secara bersamaan yang terdiri dari obesitas sentral, dislipidemia, resistensi insulin, dan ketidakstabilan tekanan darah yang dapat diperbaiki melalui produk pangan fungsional. …”
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Maternal neonicotinoid pesticide exposure impairs glucose metabolism by deteriorating brown fat thermogenesis by Wenwen Zhu, Jiali Fang, Chenbo Ji, Hong Zhong, Tianying Zhong, Xianwei Cui

“…Exposure to mixed NEOs during gestation resulted in elevated glucose levels and impaired insulin sensitivity in normal pregnant and GDM mice models. …”
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The synergistic effect of the triglyceride-glucose index and a body shape index on cardiovascular mortality: the construction of a novel cardiovascular risk marker by Hao-ming He, Ying-ying Xie, Qiang Chen, Yi-ke Li, Xue-xi Li, Sun-jing Fu, Na Li, Yan-ru Han, Yan-xiang Gao, Jin-gang Zheng

“…Abstract Background Insulin resistance, represented by increased triglyceride-glucose (TyG) index levels, shows interplay with visceral obesity and together promotes cardiovascular diseases and mortality. …”
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A systematic review of plant-based therapy for the management of diabetes mellitus in the East Africa community by Nancy Bonareri Mitaki, Ilemobayo Victor Fasogbon, Onyinye Vivian Ojiakor, Wusa Makena, Emmanuel O. Ikuomola, Reuben Samson Dangana, Ibe Micheal Usman, Ekom Monday Etukudo, Augustine Oviosun, Swase Dominic Terkimbi, Elizabeth Bessy Umoren, Angela Mumbua Musyoka, Solomon A Mbina, Esther Ugo Alum, Ibrahim Babangida Abubakar, Godson Emeka Anyanwu, Patrick Maduabuchi Aja

“…We extracted and analyzed information from the literature and showed that seven medicinal plants reduce blood sugar levels and insulin sensitivity through their mechanism of action. …”
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Reduction of intestinal RIPK1 ameliorates HFD-induced metabolic disorders in female mice by Ye Yuan, Xiaomin Hu, Chunguang Guo, Yihua Xu, Shihan Li, Wei Wen, Xinli Hu, Fanxin Zeng, Weiyi Cui, Wenli Chen, Xueting Sun, Ning Hou, Jue Wang, Rui-Ping Xiao, Xiuqin Zhang

“…Accordingly, HFD-induced metabolic disorders, including obesity, impaired glucose tolerance, insulin resistance, and dyslipidemia, are significantly ameliorated in the Ripk1IEC+/− female mice. …”
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