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Salvia deserti Decne., an endemic and rare subshrub from Arabian desert: antidiabetic and antihyperlipidemic effects of leaf hydroethanolic extracts
Published 2025-02-01“…The presence of several phenolic compounds (derivatives of ferulic, coumaric, and caffeic acids, among other derivatives) could at least in part explain the obtained data and empower the use of S. deserti as a source of bioactive ingredients with antioxidant, antidiabetic and antihyperlipidemic properties.DiscussionOur research has unveiled S. deserti as a source of potential to effectively manage diabetes and its associated dyslipidemia by improving antioxidant status, recovery of the liver and kidney functions and presumably by increasing insulin secretion and sensitivity of peripheral tissues to insulin.…”
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82
Clinical and Pathogenetic Parallels of Nonalcoholic Fatty Liver Disease and Gallstone Disease
Published 2019-03-01“…These include central and peripheral insulin resistance, changes in the expression of transcription factors (liver X-receptor and farnesoid X-receptor) and the bile acid membrane receptors (TGR5). …”
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83
Liver Damage in Type 1 Diabetes Mellitus
Published 2021-06-01“…Its important link is a likely inherited non-physiological insulin supply to the tissue, especially at marked glycaemic fluctuations. …”
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84
Treatment adherence of diabetes mellitus patients: Is it affected by demographic and patient-related factors? A literature review
Published 2023-06-01“…Based on these studies, patients with diabetes mellitus show quite low adherence to insulin therapy. The perceptions about the disease of diabetes, the availability of drugs, the diabetes education provided, perceptions of medication, current patients’ employment, younger age, educational level, nationality, HbA1c levels, abstinence from alcohol, presence of peripheral vascular disease, income, keeping their appointments in primary health care, and the religious beliefs about healing and healing practices are important factors influencing the compliance of patients with diabetes in their treatment. …”
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85
Empty Calories in Processed Foods: A Comprehensive Review of Dietary Implications
Published 2024-12-01“…There indeed presence of excess added sugar, excess solid fat, excess sodium. Added sugar causes insulin resistance and other comobidities, solid fat causes clogging of blood vessels and further aftermaths, sodium elicit hypertension. …”
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86
Curcumin inhibits growth and triggers apoptosis in human castration-resistant prostate cancer cells via IGF-1/PI3K/Akt pathway
Published 2025-02-01“…Expression levels of insulin-like growth factor 1 receptor (IGF-1R) were determined by reverse transcription quantitative polymerase chain reaction (RT-qPCR) and western blotting. …”
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87
The effects of magnesium supplementation in autoimmune rheumatic diseases
Published 2024-11-01“…Only one study fulfilled the inclusion criteria and demonstrated that 300 mg/day of oral magnesium reduced insulin resistance in rheumatoid arthritis patients. …”
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88
Unilocular adipocyte and lipid tracer for immunofluorescent images
Published 2025-02-01“…Adipocyte cellular size has been recognized as an indicator of cellular status; hypertrophic adipocytes are more prone to insulin resistance and the secretion of pro-inflammatory cytokines. …”
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89
The Association of COPD Exacerbations with New Onset Type 2 Diabetes among Medicare Patients
Published 2017-11-01“…Exacerbations of COPD are commonly treated with corticosteroids, a class of drug known to cause insulin resistance. The objective of this study was to assess the rate of exacerbations requiring emergency room visits, hospitalizations or any medical encounter (a combination of emergency room and hospitalizations) between COPD patients who did and did not develop type 2 diabetes. …”
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90
Principles of management of patient with asymptomatic elevation of serum aminotransferases
Published 2011-02-01“…For treatment of nonalcoholic steatohepatitis it is rational to use as drugs of choice metformin (treatment of insulin resistance) and ursodeoxycholic acid (anti-oxidative properties).…”
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91
Patient Knowledge About Diabetes: Illness Symptoms, Complications and Preventive Personal Lifestyle Factors
Published 2022-08-01“…Most respondents indicated that insulin injection (92%) and avoiding sugary foods (91.6%) were the best ways to control blood sugar. …”
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92
Delving into the therapeutic prospects of desmostachya bipinnata (L.) in the context of polycystic ovary syndrome (PCOS): A comprehensive review
Published 2025-02-01“…Background: PCOS, a prevalent endocrine condition in reproductive years, exhibits irregular ovulation, polycystic ovaries, insulin resistance, and elevated androgen levels. …”
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93
Type 2 diabetes remission through lifestyle intervention in a geriatric patient with long-standing diabetes and at thirty-three-months follow-up
Published 2025-02-01“…The patient showed an improvement in HbA1c (7.7 to 5.3%) and insulin resistance (HOMA-IR; 6.2 to 1.8) and a shift in BMI (25.3 to 23.7 kg/m2) through weight loss (73 to 67 kg). …”
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94
The role of non-alcoholic fatty liver disease in the formation of atherosclerotic vascular lesions in patients with abdominal obesity
Published 2018-08-01“…The relationship between the presence of NAFLD, initial manifestations of atherosclerosis and insulin resistance was established. This resulted in the rank of prognostic factors based on severity of carotid artery changes, making it possible to conclude individual atherosclerotic risk score for AD and different forms of NAFLD. …”
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95
Whole Exome Sequencing Reveals Rare Variants in Genes Associated with Metabolic Disorders in Women with PCOS
Published 2023-10-01“…PCOS patients with identified variants exhibited significantly higher average body mass index and fasting insulin levels of PCOS subjects with identified variants compared to those without variants (P < 0.05). …”
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96
Bioprinting of bespoke islet-specific niches to promote maturation of stem cell-derived islets
Published 2025-02-01“…However, stem cell (SC)-derived islets generated in vitro often lack the three-dimensional extracellular microenvironment and peri-vasculature, which leads to the immaturity of SC-derived islets, reducing their ability to detect glucose fluctuations and insulin release. Here, we bioengineer the in vivo-like pancreatic niches by optimizing the combination of pancreatic tissue-specific extracellular matrix and basement membrane proteins and utilizing bioprinting-based geometrical guidance to recreate the spatial pattern of islet peripheries. …”
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97
Maternal exposure to tris (2-butoxyethyl) phosphate induces F0 female reproductive toxicity and offspring developmental toxicity in zebrafish
Published 2025-01-01“…Additionally, a notable reduction in protein level in eggs and the gene expression of both the hormone/insulin-like growth factor (GH/IGF) and hypothalamic-pituitary-thyroid (HPT) pathways were observed. …”
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98
A Study of Serum Adiponectin Levels in Patients with Polycystic Ovarian Syndrome and its Correlation with Various Cardiometabolic Risk Markers
Published 2023-10-01“…Materials and Methods: All the included subjects underwent detailed clinical, biochemical and hormonal evaluation, including lipid profile, 75 g oral glucose tolerance test, fasting serum insulin, fasting serum adiponectin, oxLDL, total testosterone and anti-Mullerian hormone. …”
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99
Innovation of kwetiau with red rice and red bean flour: evaluation of nutritional value and potential fiber source for patients with diabetes mellitus
Published 2025-02-01“… Diabetes mellitus is characterized by hyperglycemia and metabolic dysfunctions in carbohydrates, fats, and proteins, primarily due to impaired insulin action and/or secretion. Dietary fiber can help delay carbohydrates conversion to glucose, slow the rise in blood sugar, and aid in blood sugar regulation. …”
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100
Association between TyG related parameters and metabolic dysfunction associated fatty liver disease among nondiabetic individuals
Published 2025-02-01“…TyG index and its related parameters TyG-WHtR, TyG-WC and TyG-BMI have been proven to label insulin resistance reliably, which makes it an important parameter to reflect the composition and health status of human body. …”
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