Hemophilia A Complicated by Ulcerative Colitis by Maxim Olivier, Mario Madruga, S. J. Carlan, Li Ge

“…Ulcerative colitis (UC) is an inflammatory bowel disease (IBD) that is reported to have a decreased frequency of occurrence in subjects with coagulation disorders. …”
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Personalization of thiopurine therapy: Current recommendations and future perspectives by Urbančič Dunja, Pasha Flaka, Šmid Alenka, Mlinarič-Raščan Irena

“…Despite great therapeutic advances in the field of biologics, small synthetic molecules such as thiopurines, including azathioprine, mercaptopurine, and thioguanine, remain an important therapeutic pillar in the treatment of inflammatory bowel disease, other autoimmune disorders, and cancer. …”
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Recent Advances in ADAM17 Research: A Promising Target for Cancer and Inflammation by Marcia L. Moss, Dmitry Minond

“…ADAM17 inhibitors have broad therapeutic potential, with properties ranging from tumor immunosurveillance and overcoming drug and radiation resistance in cancer, as treatments for cardiac hypertrophy and inflammatory conditions such as inflammatory bowel disease and rheumatoid arthritis. This review focuses on substrates and inhibitors identified more recently for ADAM17 and their role in cancer and inflammation.…”
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Exercise and Crohn’s Disease: Speculations on Potential Benefits by Victor Ng, Wanda Millard, Constance Lebrun, John Howard

“…Crohn’s disease (CD) is a chronic inflammatory bowel disease that affects nearly one million people in the United States and Canada. …”
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Xi Lei San Attenuates Dextran Sulfate Sodium-Induced Colitis in Rats and TNF-α-Stimulated Colitis in CACO2 Cells: Involvement of the NLRP3 Inflammasome and Autophagy by Zhang Tao, Xiaoqing Zhou, Yan Zhang, Wenfeng Pu, Yi Yang, Fuxia Wei, Qian Zhou, Lin Zhang, Zhonghan Du, Ji Wu

“…Objective. Inflammatory bowel disease (IBD) is a chronic nonspecific inflammatory bowel disease with an unclear etiology. …”
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Regulation of electrolyte transport with IL-1β in rabbit distal colon by F. R. Homaidan, H. Desai, L. Zhao, G. Broutman, R. Burakoff

“…Interletrkin-1β levels are elevated in inflammatory bowel disease. In this study the mechanism by which interleukin-1β affects electrolyte transport in the rabbit distal colon, was investigated. …”
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Histopathology of Infectious Colitis by Christina M. Surawicz

“…First, colonic mucosal biopsy can often reliably differentiate acute self limited colitis (ASLC). or infectious type colitis, from idiopathic inflammatory bowel disease (IBD). In ASLC, crypt architecture is normal and the inflammatory infiltrate in the lamina propria predominantly acute, ie, polymorphonuclear cells. …”
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Toll-Like Receptor 2 as a Regulator of Oral Tolerance in the Gastrointestinal Tract by Matthew C. Tunis, Jean S. Marshall

“…Food allergy, other adverse immune responses to foods, inflammatory bowel disease, and eosinophilic esophagitis have become increasingly common in the last 30 years. …”
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Metagenomics approaches for studying the human microbiome by Biniam Moges, Degisew Yinur Mengistu

“…The human microbiota plays a crucial role in the environment and human health under normal circumstances; nonetheless, dysfunction of the human microbiome has been associated with illnesses ranging from inflammatory bowel disease to multidrug-resistant infections. …”
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Hepatic Portal Venous Gas: A Report of Two Cases and a Review of the Epidemiology, Pathogenesis, Diagnosis and Approach to Management by Saleh Alqahtani, Carla S Coffin, Kelly Burak, Fred Chen, John MacGregor, Paul Beck

“…The most common precipitating factors include ischemia, intra-abdominal abscesses and inflammatory bowel disease. However, HPVG has recently been recognized as a rare complication of endoscopic and radiological procedures. …”
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Pyoderma Gangrenosum and Autoimmune Chronic Active Hepatitis in a 17-Year-Old Female by Joanne M. Langley, Eve A. Roberts, Moshe Ipp, Ronald M. Laxer, Lionel Boxall, M. James Phillips

“…Although there was no hepatosplenomegaly, serum aminotransferases and immunoglobulin G were elevated; antismooth muscle antibodies were detectable. Inflammatory bowel disease was not presenr. Autoimmune chronic active hepatitis and pyoderma gangrenosum are a rare association and this is the youngest patient in whom the association has been reported.…”
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A Case of Cerebral Vasculitis Associated with Ulcerative Colitis by Naveen Raj, Matthew Arkebauer, Barry Waters, Brucha Dickinson

“…Central nervous system disease associated with UC is a rare sequela of inflammatory bowel disease, occurring in less than 5% of cases. …”
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Gut Microbiome: An Intersection between Human Genome, Diet, and Epigenetics by Abdullahi Y. Muhammad, Malik Amonov, Atif A. Baig, Farrukh J. Alvi

“…Specific genetic variants in genes that are responsible for maintaining the composition of the gut commensal, such as genes of the immune system, are described to result in gut dysbiosis that can lead to the development of several autoimmune diseases such as inflammatory bowel disease and type-1 diabetes. Similarly, the diet of an individual shapes the gut microbiota by allowing the predominance of microbes that metabolize an abundant macromolecule in the diet. …”
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Interactions of the Intestinal Epithelium with the Pathogen and the Indigenous Microbiota: A Three-Way Crosstalk by C. V. Srikanth, Beth A. McCormick

“…Even slight perturbations in this equilibrium may be detrimental to the host leading to severe bacterial infection or even autoimmune diseases like inflammatory bowel disease. Several experimental model systems, including germ-free mice and antibiotic-treated mice, have been used by various researchers to study this complex relationship. …”
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The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 I... by Geir Hetland, Egil Johnson, Torstein Lyberg, Gunnar Kvalheim

“…Agaricus blazei M is rich in the immunomodulating polysaccharides, β-glucans, and has been shown to have antitumor, anti-infection, and antiallergic/-asthmatic properties in mouse models, in addition to anti-inflammatory effects in inflammatory bowel disease patients. These effects are mediated through the mushroom's stimulation of innate immune cells, such as monocytes, NK cells, and dendritic cells, and the amelioration of a skewed Th1/Th2 balance and inflammation.…”
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Posterior Cerebral Infarction following Loss of Guide Wire by Jean-Marc Bugnicourt, Denis Belhomme, Bruno Bonnaire, Jean-Marc Constans, Cécile Manaouil

“…We report the first case of delayed posterior cerebral infarction following loss of guide wire after left internal jugular venous cannulation in a 46-year-old woman with a history of inflammatory bowel disease. Our observation highlights that loss of an intravascular guide wire can be a cause of ischemic stroke in patients undergoing central venous catheterization.…”
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Genetic Factors in Animal Models of Intestinal Inflammation by R Balfour Sartor

“…Identification of the immunological mechanisms of host genetic susceptibility and the genetic basis of spontaneous colitis should provide new insights into the pathogenesis of human inflammatory bowel disease.…”
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Wound irrigation and peritoneal lavage with antiseptic/antibiotic solution before wound closure during gastrointestinal surgery: a systematic review and meta-analysis by Motoi Uchino, Koji Tamura, Shinsuke Nomura, Seiichi Shinji, Keita Kouzu, Hiroji Shinkawa, Tomohiro Ishinuki, Toru Mizuguchi, Hiroki Ohge, Seiji Haji, Junzo Shimizu, Yasuhiko Mohri, Chizuru Yamashita, Yuichi Kitagawa, Katsunori Suzuki, Motomu Kobayash, Masahiro Kobayashi, Yuki Hanai, Hiroshi Nobuhara, Hiroki Imaoka, Masahiro Yoshida, Toshihiko Mayumi, Hiroki Ikeuchi, on behalf of SSI Prevention Guideline Committee in Japan Society for Surgical Infection

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Towards painless and productive research relationships: reflections on study design by a researcher with chronic pain for participants with chronic pain by Catherine Wilkinson

“…From the perspective of a researcher with Ankylosing Spondylitis (AS), a form of inflammatory arthritis characterized by chronic pain, and Crohn's disease, a type of inflammatory bowel disease, characterized by stomach and joint pain, this paper provides insight into pain and researcher-participant relationships, from the perspective of a researcher in pain, designing a study to accommodate her own pain needs, as well as anticipating the needs of prospective participants in pain. …”
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Confocal Endomicroscopy of Colorectal Polyps by Vivian M. Ussui, Michael B. Wallace

“…Immediate potential applications of CLE are to guide biopsy sampling in Barrett's esophagus and inflammatory bowel disease surveillance, evaluation of colorectal polyps, and intraductal imaging of the pancreas and bile duct. …”
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