Pain in pancreatitis: issue and ways out by A. V. Okhlobystin

“…To present the modern data on pain sensitivity at pancreatic lesion, interrelation of mechanisms of inflammation and nociception, to determine main directions in pain relief at chronic pancreatitis (CP), to demonstrate potentials of modern enzyme preparations for this purpose.Original points. …”
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Anti-allergic potentials of Ceriops decandra leaves in TDI-induced allergic mice: Comprehensive in-vivo and in-silico studies by Aishwarja Dey, Subarna Rani, Rabindra Nath Acharyya, Apurba Kumar Barman, Khondoker Shahin Ahmed, Nripendra Nath Biswas, Shrabanti Dev, Asish Kumar Das

“…This plant has been traditionally used to treat hepatitis, liver disorders, ulcers, diarrhea, gastrointestinal disorders, hemorrhage, pain, inflammation etc. Here we investigated the safety and anti-allergic potential of C. decandra leaves. …”
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Repeated exposure to low doses of light induces retinal damage in vivo in a wavelength-dependent manner by Anaïs Françon, Laurent Jonet, Francine Behar-Cohen, Alicia Torriglia

“…We show that rats repeatedly exposed to blue and white lights display irreversible retinal damage, characterized by a degradation of the global retinal structure, a significant photoreceptor loss, and an increase of stress and inflammation markers. We highlight the role of green wavelengths in the phototoxicity of white light and show the protective effect of the addition of red light to mitigate the phototoxicity of blue light. …”
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Cyanidin and Cyanidin-3-Glucoside Alleviate Peptic Ulcer Disease: Insights from in vitro, and in vivo Studies by Prayoga DK, Aulifa DL, Budiman A, Levita J, Jiranusornkul S

“…Cyanidin and C3G were described to be able to alleviate PUD by inhibiting the cytokine pro-inflammatory, reducing inflammation in gastric mucosa, and reducing lipid peroxidation in the gastric mucosa. …”
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Impact of parathyroidectomy on inflammatory and cardiovascular risk parameters in primary hyperparathyroidism: a retrospective analysis by Nese Bulbul, Suat Sen, Fettah Acibucu

“…Multivariable regression analysis demonstrated that postoperative PTH levels were significantly associated with calcium (B = 39.82, Beta = 0.321, p = 0.0469), NLR (B = 110.02, Beta = 0.428, p = 0.0384), baseline comorbidity scores (B = -30.54, Beta = -0.287, p = 0.0361), and preoperative inflammation levels (B = 25.69, Beta = 0.311, p = 0.0386). …”
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Pathogenetic Substantiation of the Therapeutic Impact on Microbiota in Irritable Bowel Syndrome by Yu. O. Shulpekova, G. H. Babaeva, V. Yu. Rusyaev

“…The development of a lowactivity inflammation in IBS can partly be explained by the increased interaction of flagellin with the corresponding receptor, as well as the influx of excess bacteria from the small intestine. …”
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Non-alcoholic fatty liver disease: comparative assessment of diagnostic and treatment approaches in the Russian Federation and People’s Republic of China by M. Ch. Semenistaya, Fan Jian-Gao, O. B. Velichenko, Ye. A. Kuznetsova, Ch. S. Pavlov

“…Results of clinical efficacy estimation of the new drug Bicyclol in the Russian market, that it was developed in the People’s Republic of China demonstrate reduction of severity of inflammation, steatosis, fibrosis and decrease of NAFLD activity scores.…”
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Bee Venom—A Potential Complementary Medicine Candidate for SARS-CoV-2 Infections by Keneth Iceland, Kasozi, Simon Peter, Musinguzi

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is characterized by severe cytokine storm syndrome following inflammation. SARS-CoV-2 directly interacts with angiotensin-converting enzyme 2 (ACE-2) receptors in the human body. …”
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A study to correlate the association of Gender, Age, Physiology (GAP) index and radiological patterns in interstitial lung disease by Aditya Shashi Bhushan, B L Shashibhushan, K Ashwin

“…Background: Interstitial lung disease (ILD) encompasses a heterogeneous group of disorders characterized by inflammation and fibrosis of lung tissue, leading to impaired gas exchange and respiratory failure. …”
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Budesonide in treatment of alcohol-induced severe hepatitis: results of randomized trial by I. I. Komkova, M. V. Mayevskaya, V. T. Ivashkin

“…To determine efficacy and safety of budesonide and prednisolone at alcoholinduced hepatitis (AH) of severe course on development of inflammation and results of the functional hepatic tests, to estimate treatment response and short-term survival rate of patients.Material and methods. …”
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Prospective evaluation of the diagnostic accuracy of FDG-PET/CT for the detection of sternal wound infection post-sternotomy by Angela Cai, Mehrshad Bakhshi, Yoan Lamarche, Francois Harel, Matthieu Pelletier-Galarneau

“…In recent years, the use of 18F-Fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) in diagnosing infections and inflammation has expanded significantly, with a growing number of clinical indications. …”
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Metabolic syndrome and pancreatic lesions by O. S. Shifrin, I. A. Sokolina, A. E. Leonovich, M. A. Ashitko, T. L. Lemina, A. V. Korolyov

“…Steatosis of the pancreas can be considered as diffuse development of fatty tissue in all parts of the organ, developing mainly on the background of metabolic syndrome and combined to smoldering pancreatic inflammation under influence of pancreatoxic factors – alcohol, gallstone disease. …”
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Proximity extension assay revealed novel inflammatory biomarkers for follicular development and ovarian function: a prospective controlled study combining serum and follicular flui... by Chong Wang, Ying Feng, Yu Chen, Xianhua Lin, Xiangjuan Li

“…BackgroundMany components in follicular fluid (FF), such as peptide hormones, cytokines, and steroids, undergo dynamic changes during folliculogenesis and have important roles in follicular development. Because systemic inflammation has also been found to contribute to diminished ovarian reserve (DOR) in previous studies, do certain serum/FF inflammatory biomarkers affect both follicular development and ovarian function?…”
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Real-World Health Care Outcomes and Costs Among Patients With Juvenile Idiopathic Arthritis in Spain by Jordi Antón, Estefania Moreno Ruzafa, Mireia Lopez Corbeto, Rosa Bou, Judith Sánchez Manubens, Sonia Carriquí Arenas, Joan Calzada Hernández, Violetta Bittermann, Carolina Estepa Guillén, Juan Mosquera Angarita, Lucía Rodríguez Díez, Estíbaliz Iglesias, Miguel Marti Masanet, Berta Lopez Montesinos, Maria I. González Fernández, Alfonso de Lossada, Carmen Peral, Mónica Valderrama, Noelia Llevat, María Montoro Álvarez, Immaculada Calvo Penadés

“…**Background:** Juvenile idiopathic arthritis (JIA) is the most frequent chronic rheumatic disease in children. If inflammation is not adequately treated, joint damage, long-term disability, and active disease during adulthood can occur. …”
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Pan-caspase inhibitor protects against noise-induced hearing loss in a rodent model by Maria Fernanda Yepes, Kayla Minesinger, Federica M. Raciti, Maria Camila Salazar, Suhrud M. Rajguru, Suhrud M. Rajguru, Suhrud M. Rajguru

“…Underlying mechanisms behind NIHL include elevated reactive oxygen species and inflammation, all which ultimately lead to cellular apoptosis. …”
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Exploring the association between statins use or HMG-CoA reductase inhibition and migraine: a systematic review and meta-analysis by Hamdy A. Makhlouf, Amr K. Hassan, Nereen A. Almosilhy, Ahmed S.A. Osman, Shrouk Ramadan, Moaz Elsayed Abouelmagd

“…Abstract Background Statins or 3‑hydroxy‑3‑methyl‑glutarylcoenzyme A (HMG‑CoA) reductase inhibitors are medications that act by reducing the cholesterol content of liver cells Moreover, statins have been found to improve endothelial function and reduce vascular wall inflammation. A growing body of research suggests that statins are associated with less risk of migraine, and they can be used to treat symptoms. …”
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Blimp-1 orchestrates macrophage polarization and metabolic homeostasis via purine biosynthesis in sepsis by Wenjuan Peng, Qiushi Qin, Rui Li, Yujia Liu, Lan Li, Yue Zhang, Liuluan Zhu

“…Abstract Sepsis is a life-threatening condition characterized by a dysregulated immune response to infection, leading to systemic inflammation and organ dysfunction. Macrophage polarization plays a critical role in pathogenesis of sepsis, and the influence of B lymphocyte-induced maturation protein-1 (Blimp-1) on this polarization is an underexplored yet pivotal aspect. …”
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Genomic characterization of chronic lymphocytic leukemia in patients of African ancestry by Cecilia Bonolo de Campos, Chantal E. McCabe, Laura A. Bruins, Daniel R. O’Brien, Sochilt Brown, Renee C. Tschumper, Cristine Allmer, Yuan Xiao Zhu, Kari G. Rabe, Sameer A. Parikh, Neil E. Kay, Huihuang Yan, James R. Cerhan, John N. Allan, Richard R. Furman, J. Brice Weinberg, Danielle M. Brander, Diane F. Jelinek, Marta Chesi, Susan L. Slager, Esteban Braggio

“…Furthermore, we found transcription enrichment of the Tumor Necrosis Factor-alpha (TNFα) Signaling via NF-κB pathway in AA CLL compared to EA CLL, suggesting that tumor promoting inflammation plays an important role in AA CLL. In summary, these results suggest that genomic instability and NF-kB activation is more prevalent in AA CLL than EA CLL.…”
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Chemical characterization of Siraitia grosvenorii granules and their efficacy and mechanism of action on PM2.5-induced acute lung injury by Qi Shao, Yan Zhao, YuYu Shi, Fafeng Cheng, ZeHan Zhang, Ying Liu, ChangXiang Li, ZiLin Ren, Hua Bai, Haojie Cheng, Rolando Maddela, Junqiang Tian, Xueqian Wang

“…However, SGG reversed these changes, particularly tissue damage and oxidative stress, suggesting that lung protection is mediated by the antioxidant effect, which mitigates the release of alarmin and inflammation.…”
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Nutrition and Physical Therapy in the Prevention and Treatment of Endometriosis by Paulina Krzemińska, Maciej Gołębski, Wojciech Nowak, Jagoda Mikołajczyk, Zuzanna Kukla, Stella Mieruszyńska, Izabela Sadowska, Joanna Kołodziej, Mirosław Sawicki, Jakub Włosiański, Sebastian Musialik

“…However, available studies show that diet and physical activity reduce inflammation that occurs in endometriosis. They have a positive effect on markers of oxidative stress. …”
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