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A descriptive study of syphilitic uveitis in patients treated at tertiary hospitals in Johannesburg
Published 2025-01-01“…Background: Syphilitic uveitis is a ‘great mimicker’ with a myriad of manifestations resembling other forms of inflammation in the eye. A large percentage of patients with syphilitic uveitis in South Africa have HIV co-infection and their clinical features and serological results may be confounded by the presence of HIV. …”
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322
Optimization of the cholesterol gallstone model in C57BL/6 mice and evaluation of Lactobacillus intervention effects
Published 2025-02-01“…Histological analysis also revealed that probiotic intervention reduced inflammation and pathological changes in the liver and gallbladder. …”
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323
Investigating the mechanistic role of oxidative stress in brain–gut axis disruption in rat model
Published 2024-11-01“…These findings suggest that endotoxin disrupts the gut’s antioxidant system and triggers inflammation, which could potentially lead to gut dysfunction. …”
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324
Genetics of Inflammatory Bowel Disease: Current Understanding and Future Directions
Published 2024-12-01“…These genetic variants, integral to IBD's etiology of IBD, have functional significance because they perturb immune regulation, compromise epithelial barrier integrity, and disrupt mucosal homeostasis, collectively contributing to intestinal inflammation through diverse mechanisms. Early detection of IBD is paramount for arresting disease progression and underscoring the importance of prognostic testing and genetic screening, especially in cases with familial predispositions or very early onset IBD. …”
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325
Serum hepcidin level with iron profile assay might replace bone marrow iron study as a diagnostic tool for evaluation of anemia in elderly without chronic renal disease
Published 2025-01-01“…Methodology: Hundred elderly patients (≥60 years of age) having iron deficiency anemia (IDA) or anemia of chronic disease/inflammation (ACD) were the study subjects with 15 age-matched healthy controls. …”
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326
Duodenal Eosinophilia in Functional Dyspepsia
Published 2023-08-01“…Morphological examination of the stomach showed phenomena of mild chronic inflammation without intestinal metaplasia or glandular atrophy. …”
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327
Exploratory study on the efficacy of topical pan-JAK inhibitor in ocular and skin GVHD in a sclerodermatous GVHD mouse model
Published 2025-01-01“…Pathological and immunohistochemical analyses revealed a substantial reduction in inflammation and pathological fibrosis of the skin and eyelids in delgocitinib-treated GVHD mice. …”
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328
Functional Disorders of the Biliary Tract and Cholelithiasis: Analysis of a Possible Relationship
Published 2024-10-01“…Lithogenic bile provokes inflammation of low grades in the mucous membrane of the biliary tract, decreased contractility of the gallbladder and impaired relaxation of the biliary sphincters, impaired physiological response to cholecystokinin. …”
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329
Forsythia suspensa leaf fermented tea extracts attenuated oxidative stress in mice via the Ref-1/HIF-1α signal pathway and modulation of gut microbiota
Published 2025-02-01“…FSLFT has been shown to have antioxidant effects via the Redox Factor-1(Ref-1)/ hypoxia-inducible factor-1 alpha (HIF-1α) pathway, reduce inflammation caused by hydrogen peroxide through the Toll-like receptor 4 (TLR4)/nuclear factor kappa-B (NF-κB) signaling pathway, and protect mouse colons from oxidative stress by repairing gut microbiota imbalance and increasing microbial diversity and abundance. …”
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330
Comparative Analysis of Biomarkers in Type 2 Diabetes Patients With and Without Comorbidities: Insights Into the Role of Hypertension and Cardiovascular Disease
Published 2024-02-01“…Objectives: Diabetes may have a common etiology based on inflammation and oxidative stress that may provide additional information about disease progression and treatment options. …”
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331
Investigation of the association between circulating inflammatory proteins and encephalitis risk in Europeans by two-sample Mendelian randomization analysis
Published 2025-02-01“…BackgroundCytokines are powerful immune response factors that operate at inflammation sites and are also found in the blood. Nevertheless, research on encephalitis and these circulating inflammatory proteins is quite limited.MethodsThis study investigated the potential causal effects of 91 circulating inflammatory proteins on three different types of encephalitis using a two-sample Mendelian randomisation analysis. …”
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332
Association between exposure in the cement production industry and non-malignant respiratory effects: a systematic review
Published 2017-04-01“…A dose–response relationship between exposure and decline in lung function has only been shown in 1 cohort. 2 studies have detected small increases in FeNO levels during a work shift; 1 study reported signs of airway inflammation in induced sputum, whereas another did not detect an increase in hospitalisation rates.Conclusions Lack of power, adjustment for possible confounders and other methodological issues are limitations of many of the included studies. …”
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333
Biocompatibility of new cement based capping material prepared from eggshell and biopolymer (chitosan).
Published 2022-07-01“…Results: The histological preparation in control group at 7 days time period demonstrated simple inflammatory reaction represented by slight looseness of the collagen fibers with increase the extracellular spaces between the fibers indicating mild edematous inflammation. For the Experimental group, MTA and Biodentine group there was great similarity in the tissue reaction when comparedwith control group. …”
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334
Diagnostic Algorithm for Joint Pain in Patients with Inflammatory Bowel Disorders
Published 2022-01-01“…IBD-associated arthritis was diagnosed in 41 (42.3%) cases, osteoarthritis — in 38 (39.2%) IBD patients with joint pain, arthralgia with no objective inflammation, impaired joint function or lesions in X-ray and/or ultrasound — in 13 (13.4%) patients.Conclusion. …”
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335
Intrastromal autologous implantation of adipose derived adult stem cells for the management of established corneal scars
Published 2025-03-01“…Observations: ADASC were isolated by elective liposuction, and a solution composed of 3x106 ADASC contained in 1mL saline was used to soak a corneal intrastromal pocket created with femtosecond laser at mid-depth. No signs of inflammation or rejection were observed. One year after surgery, we observed a complete restoration of the pre-existing corneal stroma scars, observed both clinically and by anterior segment OCT. …”
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336
Efficacy and Safety of Bicyclol Treatment for Non-Alcoholic Fatty Liver Disease: Results of a Cohort Study
Published 2018-09-01“…Bicyclol therapy in NAFLD is accompanied by positive dynamics of inflammation activity markers, insulin resistance and lipid spectrum, which suggests a positive dynamics of the stages of liver fibrosis and steatosis.…”
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337
Neuroprotective role of epigallocatechin-3-gallate, albeginin and melanoxetin in alzheimer's disease
Published 2025-02-01“…The rats treated with these phytocompounds showed a significant reduction in oxidative stress, inflammation, Aβ plaque formation, neurofibrillary tangles, and anticholinesterase activity. …”
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338
Exploring molecular disparities of H-type vasculature endothelial cells in osteonecrosis of the femoral head through single-cell analysis
Published 2025-02-01“…Angiogenic capacity decreased in necrotic samples, accompanied by an elevation in inflammation levels. The hypoxia index was higher, with ferroptosis increased in stage 3 A and parthanatos in stages 3 A and 4. …”
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339
Biogenesis, characterization, and applications of Spirulina selenium nanoparticles
Published 2025-02-01“…Moreover, SP-SeNPs could effectively alleviate the inflammation in RAW 264.7 macrophages with a reduction percentage of 8.82% in Nitric oxide concentration. …”
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