-
281
Evaluation of zonulin levels in patients with migraine
Published 2025-02-01“…The pathophysiology of migraine is based on the effect of neurogenic inflammation. The aim of the current investigation was to examine the serum zonulin level in individuals suffering from migraine. …”
Get full text
Article -
282
The efficacy of an allosteric modulator of the alpha 7 nicotinic acetylcholine receptor in a murine model of stroke
Published 2025-02-01“…However, these agents present challenges such as a limited therapeutic window, incomplete reperfusion rates, risk of transformation, reperfusion-induced inflammation, and a lack of promoting neuroprotection. …”
Get full text
Article -
283
Influence of immune cells and inflammatory factors on Alzheimer’s disease axis: evidence from mediation Mendelian randomization study
Published 2025-02-01“…While the exact etiology of AD remains unclear, immune inflammation is known to play a significant role in the disease. …”
Get full text
Article -
284
Determination of the levels of some selected metals in ocimum lamiifolium in Wolaita Zone, Southern Ethiopia
Published 2022-10-01“…Ex Benth (Damakese, in Amharic) is one of the well celebrated and most widely used home remedy for the treatment of a disease locally known as “Mitch” which is characterized by headache, fever, inflammation, joint pain, sweat, loss of appetite, etc. …”
Get full text
Article -
285
Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis
Published 2025-02-01Get full text
Article -
286
The spectrum of giant cell arteritis and polymyalgia rheumatica: a longitudinal prospective study to assess for subclinical giant cell arteritis in new onset polymyalgia rheumatica
Published 2025-02-01“…Conclusion The key finding of this study is the incorporation of the concept that vascular inflammation mainly precedes the classical clinical manifestations. …”
Get full text
Article -
287
Emergence of a novel porcine pestivirus with potential for cross-species transmission in China, 2023
Published 2025-02-01“…In piglets, histopathological examination revealed myocarditis, hepatitis, glial vacuolation and cerebrovascular inflammation. In mice, findings included hepatic monocyte aggregation, glomerular atrophy, pulmonary edema, inflammatory cell infiltration, and capillary dilation. …”
Get full text
Article -
288
A Cross-Sectional Study to Evaluate the Prevalence and Severity of Gingivitis among High School Students in Erbil City-Iraq.
Published 2024-03-01“… Background and objective: There is an increase in the gingival inflammation without an associated increase in plaque level during puberty. …”
Get full text
Article -
289
Effects of Endurance Training and Chlorogenic Acid on Oxidative and Nitrosative Stress Markers in Prediabetic Male Mice
Published 2025-01-01“…Background: Many studies have investigated the effects of exercise and chlorogenic acid in controlling and improving diabetes and reducing inflammation. This study aimed to investigate the effects of endurance exercise and chlorogenic acid on oxidative and nitrosative stress indicators in skeletal muscle tissue of male C57BL/6 mice. …”
Get full text
Article -
290
Widespread mutagenesis and chromosomal instability shape somatic genomes in systemic sclerosis
Published 2024-10-01“…We hypothesize that the inflammation and immune response associated with systemic sclerosis can trigger DNA damage, leading to elevated somatic mutagenesis, a hallmark of pre-cancerous tissues. …”
Get full text
Article -
291
Epidemiology of spinal cord injuries in three selected counties in Kenya
Published 2025-01-01“…Background: Spinal cord injury (SCI) presents a significant health challenge, characterised by damage to the spinal cord resulting from trauma, inflammation, tumours or other aetiologies. This injury often leads to a range of debilitating consequences, including loss of motor function, sensation, sphincter control and autonomic nerve function below the site of injury, as well as challenges with self-care and performance of instrumental activities of daily living (ADLs). …”
Get full text
Article -
292
The role of glucagon-like peptide-1 receptor (GLP-1R) agonists in enhancing endothelial function: a potential avenue for improving heart failure with preserved ejection fraction (H...
Published 2025-02-01“…GLP-1R agonists, including semaglutide and liraglutide, have demonstrated significant cardioprotective effects, such as improving vascular endothelial function, reducing inflammation, and preventing atherosclerosis. Clinical trials, such as the STEP-HFpEF trial, have shown positive results in reducing symptoms and physical restrictions in HFpEF patients. …”
Get full text
Article -
293
Does the consumption of soya products affect cholesterol levels, blood pressure, or other cardiovascular health indicators?
Published 2025-02-01“…Aim of the study This study aims to analyse the current state of knowledge regarding the effect of soy consumption on: hypertension, lipid profile, biomarkers of inflammation, vascular epithelium and impact on mortality caused by cardiovascular diseases. …”
Get full text
Article -
294
Movement in the Shadow of Sadness: How Physical Activity Supports the Fight Against Depression
Published 2025-02-01“…Additionally, physical effort reduces inflammation and oxidative stress, supporting brain health and countering neurodegenerative processes. …”
Get full text
Article -
295
Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections?
Published 2025-02-01“…We then focus on SARS-CoV-2 infection and show how the binding of the viral pathogen to the angiotensin-converting enzyme 2 receptor, as well as to NRP-1, leads to elevated levels of VEGF-A and consequences such as coagulation, vascular dysfunction, and inflammation. HIV infection augments angiogenesis via several mechanisms, most prominently, by the trans-activator of transcription (tat) protein mimicking VEGF-A by binding to its receptor, VEGFR-2, as well as upregulation of NRP-1, which enhances the interaction between VEGF-A and VEGFR-2. …”
Get full text
Article -
296
Therapeutic anti-inflammatory immune potentials of some seaweeds extracts on chemically induced liver injury in mice
Published 2025-02-01“…Pre- and post-treatment of CCL4/mice with the P. pavonia and J. rubens extracts ameliorated the liver damages caused by CCl4 and significantly inhibited the necrotic area, indicating hepatic cell death and decreased periportal hepatic degeneration, fibrosis, and inflammation.…”
Get full text
Article -
297
Comparison of Spatiotemporal Gait Variables Between Healthy Individuals and Patients with Heel Spur During Walking
Published 2024-11-01“…Plantar fasciitis is a common foot condition that affects gait mechanics due to pain and inflammation in the plantar fascia. Understanding these differences can provide insights into how this pathology alters gait and inform therapeutic interventions to improve function and reduce discomfort. …”
Get full text
Article -
298
Outcome of Excision with Primary Midline Closure for Sacrococcygeal Pilonidal Sinus Disease
Published 2020-12-01“…Inclusion criteria was all patients with chronic midline located sinuses without evidence of acute inflammation. Exclusion criteria was all infected ,off midline located sinuses and recurrent sinuses. …”
Get full text
Article -
299
Side Effects of Steroidal And Non-Steroidal Anti-Inflammatory Drugs on The Oral Cavity.
Published 2024-03-01“…Results: The data showed that a majority of NSAIDs users complained of gingival bleeding (39%) and Xerostomia (32%), while corticosteroid users complained of fungal infection (50%), gingival inflammation (25%) and other less frequent side effects. …”
Get full text
Article -
300
Colonic growth factors (G-CSF, GM-CSF) and chemokines (MCP-1, MIP-1β) in severe ulcerative colitis
Published 2018-08-01“…All patients underwent colectomy due to severe disease, resistant to conservative treatment. Inflammation activity was determined according to severity of erosive and ulcerative lesions of the colon. …”
Get full text
Article