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241
New Possibilities for the Treatment of Crohn’s Disease
Published 2019-12-01“…The drug interrupts the cascade of humoral and cellular reactions leading to transmural inflammation of the intestinal wall by blocking the interaction of the p40 subunit with the IL-12Rβ1 chain on the surface of T-lymphocytes and NK cells. …”
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242
Abdominal Wall Defects: Hydrogel based solutions in Abdominal Wall Reconstruction
Published 2025-01-01“…This paper explores the design and application of these hydrogels, highlighting their potential to improve surgical outcomes through enhanced tissue integration, reduced inflammation, and minimized postoperative complications. …”
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243
Profile of STING agonist and inhibitor research: a bibliometric analysis
Published 2025-02-01“…Application of STING agonists primarily focuses on cancer immunotherapy, while STING inhibitors target inflammation, particularly neuroinflammation and acute lung injury.ConclusionCurrent research emphasizes optimizing STING agonists for permeability, efficacy, and safety, with nanotechnology and lipid nanoparticles being prominent delivery techniques. …”
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244
Neuroendocrine Tumour as a Diagnostic and Prognostic Criterion for Autoimmune Gastritis
Published 2020-01-01“…The autoimmune genesis of the chronic inflammation of the gastric mucosa may serve as a background for the development of neuroendocrine tumours of the stomach, which determines the management tactics in such conditions.…”
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245
COVID-19 Pandemic and Irritable Bowel Syndrome — is there a Relationship?
Published 2022-08-01“…It has been noted that the COVID-19 may contribute to the formation of post-infectious functional gastrointestinal diseases, given that angiotensin-converting enzyme-2 (ACE-2) receptors, the site of binding of the SARS-CoV-2 virus to human cells, are also present in epithelial intestinal cells; virus was found in feces in about half of patients, gastrointestinal symptoms, including diarrhea occur in about one fifth of patients, fecal calprotectin, a marker of GI inflammation is elevated in patients with COVID-19, macroscopically as well as histologically, patients show signs of damage mucous membrane of the gastrointestinal tract, and also, as noted above, they have a dysbiosis of the intestinal microbiota.Conclusion. …”
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247
The Role of Vacuum-Assisted Wound Closure Therapy after the Surgical Treatment of the Pilonodal Sinus
Published 2019-01-01“…Cytologically, starting from the 8th day of VAC-therapy, a decrease in inflammation was observed in 24 (82.8 %) patients in the main group, with the wound regenerative processes being recorded on the 16th day in 17 (58.6 %) patients (p < 0.05). …”
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248
Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trial
Published 2022-05-01“…Research suggests that inflammation is an important mediator in the pathophysiology of anxiety disorders. …”
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249
Promotion Mechanisms of Stromal Cell-Mediated Lung Cancer Development Within Tumor Microenvironment
Published 2025-02-01“…This review aims to explore the mechanisms through which stromal cells in the tumor microenvironment promote lung cancer development, with a particular focus on how immune cells, tumor-associated fibroblasts, and endothelial cells contribute to immune suppression, inflammation, and angiogenesis. The goal is to provide new insights and potential strategies for the diagnosis and treatment of lung cancer.Keywords: tumor microenvironment, lung cancer, stromal cells, immune cells, cancer-associated fibroblasts, endothelial cells…”
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250
COVID-19 and post-disease features in patients with obesity
Published 2024-12-01“…Fatty tissue is known to support chronic low-grade inflammation and has its own endocrine activity. Over time, it became obvious that some patients still have consequences following the acute phase of COVID-19, which in some cases lead to irreversible changes in the body and reduced quality of life. …”
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251
Migratory Polyarthritis Associated With Clopidogrel: A Case Report
Published 2024-12-01“…All symptoms and signs of joint inflammation had improved within five days of stopping the Clopidogrel. …”
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252
Examining the epigenetic transmission of risk for chronic pain associated with paternal post-traumatic stress disorder: a focus on veteran populations
Published 2025-02-01“…Hence, epigenetic changes related to pain perception, inflammation, and neurotransmission may influence an individual’s predisposition to chronic pain conditions. …”
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253
Pathogenic role of intestinal microflora changes in patients with irritable bowel syndrome and treatment options
Published 2014-09-01“…In the last years more and more data appear on changes in qualitative and quantitative spectrum of intestinal microflora in combination to low degree inflammation of colonic mucosa at IBS that allowed to reconsider standard concepts on pathogenesis of this functional disorder. …”
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254
Role of heat shock protein in radiation-induced effect and related potential clinical application
Published 2025-02-01“…This paper reviews the biological effects of HSP under radiation and the latest research progress of combined radiation and HSP inhibitors or hyperthermia, in the hope of having a more comprehensive understanding of its mechanism in physiological processes such as cell survival, apoptosis, inflammation, immune response, as well as radiation response, which will help to enhance the therapeutic effect and to provide more effective and safer radiotherapy for cancer patients in the future.…”
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255
Morphological features of chronic virus-associated gastritis and duodenitis
Published 2018-08-01“…Presence of HSV-1 infection alters of the severity and activity of chronic inflammation in stomach mucosa in children and adults.…”
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256
Herbal remedies as a potential alternative therapy for arthritis
Published 2023-12-01“…Arthritis forms a vicious cycle, where upon overuse of a joint or an autoimmune reaction inflammation and pain occur. These are marked by specific molecular patterns and immunological pathways that lead to chondrolysis and destruction of cartilage. …”
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257
Psychobiotic effects of probiotics and prebiotics
Published 2018-08-01“…At a systemic level suppression of cortisol and proinflammatory cytokines production by psychobiotics maintain the positive effect on the mood due to reduction of systemic inflammation severity.…”
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258
Cystic Form of Duodenal Dystrophy (Clinical Case)
Published 2023-08-01“…The report is devoted to the description of a case of successful treatment of a cystic form of duodenal dystrophy — a chronic inflammation of the pancreatic tissue, ectopic in the wall of the duodenum. …”
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259
Prevalence of Plaque Induced Gingivitis Among Dental Students in College of Dentistry, Hawler Medical University.
Published 2024-03-01“… Background and objective: Gingival inflammation in response to bacterial plaque accumulation is considered the key risk factor for the onset of periodontitis. …”
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260
Follistatin like-1 aggravates silica-induced mouse lung injury
Published 2017-03-01“…The induced Fstl1 regulated inflammation response via activation of nod-like receptor family, pyrin domain containing 3v (NLRP3) inflammasome-mediated IL-1β production from macrophages. …”
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