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Meconium Peritonitis and Periorchitis: Report of a Prenatal Case
Published 2014-12-01“… Meconium peritonitis refers to rupture of the bowel prior to birth, resulting in fetal meconium escaping into peritoneum leading to inflammation (peritonitis). Meconium periorchitis is an extension of meconium peritonitis into the scrotum via a patent processus vaginalis. …”
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Association of neutrophil-to-lymphocyte ratio and monocyte-tolymphocyte ratio with all-cause mortality in patients with ischemia and non-obstructive coronary arteries
Published 2025-01-01“…Ischemia with non-obstructive coronary arteries (INOCA) is a frequent coronary syndrome with important impact on morbimortality. Systemic inflammation, a key pathophysiological mechanism in its development, is reflected in diverse bio-markers, such as the neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR) and platelet-to-lymphocyte ratio (PLR). …”
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224
Acetylcholine in irritable bowel syndrome pathogenesis and the role of cholineblockers
Published 2011-02-01“…Experimental data allow to assume, that «subclinical inflammation» within intestinal wall at IBS, disturbances of peristaltic activity and hyperalgesia, are related to altered response of immune and smooth-muscle cells to acetylcholine stimulation.Conclusion. …”
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Effect of rifampicin on the kidney of albino rats
Published 2013-07-01“…Histological examination of the kidney revealed an inflammation of the glomeruli for 1.10mg/120gBW treated group in 60days. …”
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227
Biological therapy for inflammatory bowel disease: cyclical rather than lifelong treatment?
Published 2024-06-01“…Treatment guidelines highlight the need for effective control of inflammation and early escalation to advanced therapies to avoid long-term complications. …”
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228
The crucial role of 5hmC in neuroprotection and repair after cerebrovascular injury
Published 2024-07-01“…The discussion delves into the dynamic interaction between hydroxymethylation and important pathways in neuroprotection, such as the modulation of excitotoxicity and cellular metabolism, resolution of inflammation, and mitigation of oxidative stress. Additionally, it explores emerging evidence suggesting that 5hmC contributes to neurorepair by promoting neurogenesis, axonal regeneration, angiogenesis, and synaptic plasticity. …”
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229
Research Progress on Human Umbilical Cord Mesenchymal Stem Cells in the Treatment of Knee Osteoarthritis
Published 2025-01-01“…Knee osteoarthritis (KOA) is a prevalent degenerative joint disease characterized by synovial inflammation, cartilage loss. Often manifesting as joint pain and limited mobility, it severely affects the quality of life of patients. …”
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230
Primary biliary cirrhosis: clinical and laboratory criteria of diagnostics and up-to-date treatment
Published 2011-09-01“…PBC is organ-specific autoimmune liver disease affecting predominantly women that is characterized by chronic progressing destruction of intrahepatic bile ducts with portal inflammation, resulting in development of liver cirrhosis (LC). …”
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Functional status, lymphocyte-to-monocyte ratio, and platelet-to-lymphocyte ratio as prognostic factors of one-year survival rate in elderly patients with advanced-stage non-small...
Published 2024-01-01“…Aging and chronic inflammation are related to its pathogenesis. Functional status, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio describe a chronic inflammation and correlate to the survival of older adults with advanced-stage (IIIB-IV) NSCLC. …”
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Effects of biologic therapy on novel indices of lung inhomogeneity in patients with severe type-2 high asthma
Published 2025-02-01“…Responders, unlike Non-Responders, experienced significant improvements in symptoms and FEV1 % predicted (Δ pre-BD FEV115±15% pred, p<0.001) and included a higher proportion of patients in clinical remission at 1 year.Conclusion σlnCl is strongly associated with systemic eosinophilic inflammation in severe type-2 high asthma. An early σlnCl response following anti-IL5 biologics identifies patients more likely to experience improvements in symptoms and lung function when systemic eosinophils are depleted. σlnCl may provide a sensitive route for tracking inflammation involving the small airways.…”
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Diagnostics and treatment of Clostridium difficile-associated disease: Guidelines of the Russian gastroenterological association
Published 2018-08-01“…Clostridium difficile-associated disease develops at disorders of intestinal microbiome with excessive colonization of C. difficile which toxins cause colonic inflammation and damage. C. difficile toxins A and B are major virulence factors causing damage of intestinal wall and inflammation due to damage of intestinal epithelial barrier, induction of proinflammatory cytokines, apoptosis and a necrosis of epithelial cells. …”
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234
Family case of cardiac achalasia
Published 2014-10-01“…Cardiac achalasia is idiopathic disease, caused by inflammation and degeneration of myenteric plexus resulting in loss of postganglionic inhibitory neurons, essential for relaxation of the lower esophageal sphincter and peristaltic contractions of the esophagus. …”
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Microbiome in development of esophageal diseases
Published 2016-08-01“…Toll-like receptors, cytokines, nuclear factor κB, cyclooxygenase-2 can be potential mediators of inflammation and carcinogenesis which expression can be modified by microbiome spectrum. …”
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Irritable Bowel and Bacterial Overgrowth Syndromes: a Bacterial Link Hypothesis of Functional Disease
Published 2021-04-01“…SIBO may represent a "peripheral" mechanism of IBS, aside to nonspecific inflammation, increased epithelial permeability and local immune system activation. …”
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Non-invasive of liver fibrosis diagnostics: the role of serum markers
Published 2015-05-01“…Investigations in the field of fibrogenesis processes made possible quantitative estimation of liver fibrosis by non-invasive tests based both on assessment of peripheral blood levels of substances, directly involved in various stages of extracellular matrix synthesis and disintegration, and on the routine laboratory tests reflecting activity of inflammation, degree of disorder of synthetic liver function and fibrosis progression.Conclusion. …”
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Sex-specific influences of APOEε4 genotype on hippocampal neurogenesis and progenitor cells in middle-aged rats
Published 2025-02-01“…Compared to healthy controls, male rats with hAPOEε4 genotype showed reduced neural stem cell-like cells and new adult-born brain cells and increased microglia (marker of inflammation in the brain) at middle age. In contrast, female rats with hAPOEε4 genotype showed increased new adult-born neurons, but no changes in the other cell types, suggesting a possible compensatory response to the effects of hAPOEε4 at this time point. …”
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Rebamipide during chronic gastritis: <i>H. pylori</i> eradication therapy and restoration of gastric mucosa barrier function
Published 2024-01-01“…Experimental and clinical studies have demonstrated that rebamipide increases concentration of prostaglandins (prostaglandin E2 and prostacyclin) and production of mucin, manages inflammation and oxidative stress, controls apoptosis and autophagy. …”
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Compliant immune response of silk-based biomaterials broadens application in wound treatment
Published 2025-02-01“…In this review, we elaborate on the inflammation and immune responses caused by the implantation of sericin and SF and also explore their anti-inflammatory properties and immune regulatory functions. …”
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