Salivary Levels of Interleukin-17 in Iranian Patients With Systemic Sclerosis by Ali Tadayon, Javad Moayedi, Mohamad Ali Nazarinia, Mahyar Malekzadeh, Sara Kazemi, Maryam Mardani

“… Systemic sclerosis (SSc) is a rare immune-mediated rheumatic disease in which the skin, muscles, blood vessels, and internal organs are damaged through chronic inflammation. Interleukin-17 (IL-17) is a potent pro-inflammatory cytokine produced by T helper 17 (Th17) cells, and plays a critical role in many inflammatory conditions. …”
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Successful rivaroxaban and doxycycline therapy for Mycoplasma pneumonia with pulmonary embolism in children: a case report by Fang Xiaoqian, Lu Hemin

“…Azithromycin, doxycycline, and piperacillin-tazobactam were administered sequentially for infection control, while methylprednisolone was given to control inflammation and heparin and rivaroxaban for sequential treatment, resulting in a satisfactory recovery.…”
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Predicting cardiovascular disease and all-cause mortality using the lymphocyte-to-monocyte ratio: Insights from explainable machine learning models by Jichao Wu, Die Huang, Jiefang Li, Jingxing Yi, Yu Lei, Jun Yin

“…This study investigates the lymphocyte-to-monocyte ratio (LMR), a simple immune biomarker associated with inflammation, to assess whether it can serve as a new marker for predicting chronic inflammation in cardiovascular disease, and compares it to traditional biomarkers. …”
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Network Pharmacology and Experimental Validation of the Therapeutic Effect of Baji Capsule on LPS-Induced Osteoporosis by Li Q, Li D, Tian C, Liu X, Wang H, Liu H

“…However, the efficacy of Baji capsule has not been reported for osteoporosis caused by oxidative stress and inflammation. Therefore, the aim of this study was to evaluate whether Baji capsule has a therapeutic effect on lipopolysaccharide (LPS)-induced inflammatory osteoporosis and to explore the underlying mechanisms through network pharmacology.Patients and Methods: Osteoporosis model in ICR mice induced with LPS. …”
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Enteric-Coated Aspirin Induces Small Intestinal Injury via the Nrf2/Gpx4 Pathway: A Promising Model for Chronic Enteropathy by Zhang M, Xia S, Feng L, Han X, Zhang Y, Huang Y, Liu Y, Zhao K, Guan J, Tian D, Liao J, Yu Y

“…Aspirin led to a shortened small intestine, macroscopic and microscopic damage to the intestinal mucosa, and local inflammation. Aspirin disrupted the intestinal barriers and increased the permeability of the small intestine. …”
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Immune system effectors as biomarkers of prognosis after acute burns in a case-control study by Alejandro Ferrari, Lorena Di Croce, Sabrina Saavedra, Marisel Hartwig, Omar Perrone, María Alejandra Guzmán

“… Burns are a global health problem due to frequent complications, which lead to systemic inflammation, acute respiratory distress syndrome, multiorgan dysfunction, and death. …”
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Deletion of ESX-3 and ESX-4 secretion systems in Mycobacterium abscessus results in highly impaired pathogenicity by Wassim Daher, Vincent Le Moigne, Yara Tasrini, Shweta Parmar, Danielle L. Sexton, John Jairo Aguilera-Correa, Valentin Berdal, Elitza I. Tocheva, Jean-Louis Herrmann, Laurent Kremer

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Synergistic toxicity of nanoplastics and Helicobacter pylori on digestive system in mice by Xiaolin Zhang, Yunqing Wang, Xiaohan Tong, Boqing Li, Sisi Liu, Yingzi Cui, Wenke Wang, Zhiqin Li, Chunlei Ma, Ying Zhang

“…These increases, accompanied by elevated TG and LDH levels, suggest aggravated inflammation, oxidative stress, and metabolic disruption. …”
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Health benefits of algae and marine-derived bioactive metabolites for modulating ulcerative colitis symptoms by Najmeh Oliyaei, Saghar Zekri, Aida Iraji, Alireza Oliyaei, Romina Tanideh, Nadiar M. Mussin, Amin Tamadon, Nader Tanideh

“…Indeed, oxidative stress, impairment of the intestinal barrier, inflammation, and dysbiosis of gut microbiota are the main pathways involved in ulcerative colitis. …”
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The SGLT-2 Inhibitors and their Role in the Treatment of Heart Failure - A Review of Literature by Silvia Ciraolo, Agnieszka Kulczycka-Rowicka, Joanna Wojda, Katarzyna Lesiczka-Fedoryj, Anna Walczak, Zuzanna Kościuszko, Adam Sobiński, Matylda Czerwonka, Katarzyna Kurza, Julianna Podolec

“…They provide various effects, including improved hemodynamics, reduced inflammation, and enhanced cardiac energy metabolism. …”
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A transcriptional profile of aging in the human kidney. by Graham E J Rodwell, Rebecca Sonu, Jacob M Zahn, James Lund, Julie Wilhelmy, Lingli Wang, Wenzhong Xiao, Michael Mindrinos, Emily Crane, Eran Segal, Bryan D Myers, James D Brooks, Ronald W Davis, John Higgins, Art B Owen, Stuart K Kim

“…Some of the genes whose transcripts increase in abundance with age are known to be specifically expressed in immune cells, suggesting that immune surveillance or inflammation increases with age. The age-regulated genes show a similar aging profile in the cortex and the medulla, suggesting a common underlying mechanism for aging. …”
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Fournier's disease and anaerobic paraproctitis – different clinical forms of same pathological process? by M. A. Yegorkin

“…At FD and AP radical elimination of suppurative focus in optimal terms (3–6 days after disease onset), subsequent complex antibacterial and detoxication therapy result in regression of signs of inflammation and convalescence of the majority of patients.Conclusion. …”
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Role of serotonin in physiology and diseases of gastro-intestinal tract by E. F. Barinov, O. N. Sulayeva

“…It determines its involvement in pathogenesis of the diseases related to disorders of motility, microcirculation, inflammation and disregeneration. Authors discuss receptor-specific effects of serotonin on blood-tissue barriers of GIT, synaptic transmission, regulation of local and systemic afferentation, motility of the stomach and intestine, and mechanisms of defense. …”
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CALLY index, but not HALP score, is associated with mortality in cirrhosis patients by Yıldız Günay, Bedel Cihan, Zortuk Ökkeş, Selvi Fatih, Karanci Yusuf

“…Cirrhosis is a chronic liver disease that is characterized by inflammation and fibrosis, as well as liver dysfunction. …”
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Associations of carbohydrate quality and cardiovascular risk factors vary among diabetes subtypes by Katharina S. Weber, Sabrina Schlesinger, Janina Goletzke, Klaus Straßburger, Oana-Patricia Zaharia, Sandra Trenkamp, Robert Wagner, Wolfgang Lieb, Anette E. Buyken, Michael Roden, Christian Herder, for the GDS group

“…Conclusions Associations of carbohydrate quality parameters with blood lipids, subclinical inflammation, and fatty liver index differed between diabetes subtypes. …”
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Exploring nutraceutical approaches linking metabolic syndrome and cognitive impairment by Rebecca Sonnino, Gea Ciccarelli, Simona Moffa, Laura Soldovieri, Gianfranco Di Giuseppe, Michela Brunetti, Francesca Cinti, Eleonora Di Piazza, Antonio Gasbarrini, Enrico C. Nista, Alfredo Pontecorvi, Andrea Giaccari, Teresa Mezza

“…Summary: Metabolic syndrome (MetS) and mild cognitive impairment (MCI) are interconnected conditions sharing common pathological pathways, such as inflammation and oxidative stress, leading to the concept of “metabolic-cognitive syndrome.” …”
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Clinical and Immunological Characteristics of Elderly Onset Rheumatoid Arthritis by LI Zhengfang, WU Chanyuan, MA Mengsi, LI Tingting, WU Xue, MENG Xinyan, ZHANG Sha, WU Lijun

“…EORA is prone to interstitial lung disease, anemia and high inflammation, and the level of peripheral blood NK cells is higher.…”
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Antihyperlipidemic and Antiinflammatory Activity of Crude Oil Anguilla Marmorata [Q.] Gaimard in White Rats (Rattus Norvegicus) by Jamaluddin Jamaluddin, Khildah Khaerati, Ihwan Ihwan, Yusriadi Yusriadi, Andi Ratihsekarningrum Siradje, Apriyana Soputra, Novita Christiana Ponganan, Klerensia Defneir Titing, Novianti Batti, Andi Mustika, Andi Alfianto, Moh. Rifki, Janes Krisly, Finta Amalinda

“…Blood cholesterol levels were measured and percent inflammation was determined. The results showed that the eel oil extracts led to a decreased of total cholesterol levels 49.60 %, triglycerides 31.15 %, and HDL 14.3 %. …”
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Combining O2 High Flow Nasal or Non-Invasive Ventilation with Cooperative Sedation to Avoid Intubation in Early Diffuse Severe Respiratory Distress Syndrome, Especially in Immunoco... by Petitjeans Fabrice, Longrois Dan, Ghignone Marco, Quintin Luc

“…COVID), the use of oxygen high flow (HFN) vs. noninvasive ventilation (NIV; conventional vs. helmet) and a multi-modal approach to avoid endotracheal intubation (“intubation”): low normal temperature, cooperative sedation, normalized systemic and microcirculation, anti-inflammation, reduced lung water, upright position, lowered intra-abdominal pressure.…”
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Kyoto International Consensus Report on Anatomy, Pathophysiology and Clinical Significance of the Gastroesophageal Junction by A. A. Sheptulin, Y. S. Rabotyagova

“…The experts reviewed and adopted 28 statements concerning (1) the definition of the gastroesophageal junction (GEJ); (2) the definition of the GEJ zone, covering the area located 1 cm proximal and 1 cm distal in relation to gastroesophageal junction; (3) the assessment of chemical and bacterial (Helicobacter pylori) factors leading to the development of inflammation, metaplasia and neoplasia of the mucosa of the GEJ; and (4) a new definition of Barrett’s esophagus.Conclusion. …”
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