Nosocomial Infection Program by Shirley Paton

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Highly stable bacteriophages PIN1 and PIN2 have hallmarks of flagellotropic phages but infect immotile bacteria by Afif Jati, Yan Li, Andre Mu, Tze Y. Thung, Huanchang Chen, Joel Steele, Han Lee, Ralf Schittenhelm, Tieli Zhou, Francesca L. Short, Rhys A. Dunstan, Trevor Lithgow

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Proportion of carbapenem-resistant Enterobacterales with readily detectable beta-lactam resistance by Eli Wilber, Gillian Smith, Jesse T. Jacob, Paulina A. Rebolledo

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Extracellular microRNAs initiate immunostimulation via activating toll-like receptor signaling pathways by Hongwei Liang, Koby Kidder, Yuan Liu

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Molecular epidemiology of Microsporidia among HIV-positive and HIV-negative patients in the Limpopo province, South Africa by Amidou Samie, Rhulani Patricia Maluleke, Nicoline Tanih, Ali ElBakri

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Cerebrospinal fluid proteomics reveals the innate immunity and blood-brain barrier dysregulation in a patient with multidrug-resistant Acinetobacter baumannii ventriculitis treated... by Mengyao Li, Dongyu Liu, Phillip J. Bergen, Silin Liang, Juan Chen, Zhi Ying Kho, Jing Lu, Huiying Sun, Weiqing Hong, Xiaofen Liu, Chengying Hong, Youlian Chen, Wei Li, Hongxia You, Shunyao Xu, Yu Wang, Huaiji Gao, Chun Hin Lam, Jian Li, Xiaoyin Chen, Xueyan Liu

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First Case of Tricuspid Valve Endocarditis Caused by Gemella bergeri by Orathai Pachirat, George Watt, Burabha Pussadhamma

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Regulation of airway fumarate by host and pathogen promotes Staphylococcus aureus pneumonia by Ying-Tsun Chen, Zihua Liu, Dario Fucich, Stefano G. Giulieri, Zhe Liu, Ridhima Wadhwa, Gustavo Rios, Henning Henschel, Nupur Tyagi, Françios A. B. Olivier, Ian R. Monk, Shivang S. Shah, Shwetha H. Sridhar, Marija Drikic, Colleen Bianco, Gaurav K. Lohia, Ayesha Z. Beg, Paul J. Planet, Ian A. Lewis, Robert Sebra, Ana Traven, Abderrahman Hachani, Timothy P. Stinear, Benjamin P. Howden, Jeffrey M. Boyd, Sebastian A. Riquelme, Chu Wang, Alice Prince, Tania Wong Fok Lung

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Daxx and HIRA go viral – How chromatin remodeling complexes affect DNA virus infection by Julia Mai, Masih Nazari, Thomas Stamminger, Sabrina Schreiner

“…Overall, Daxx and HIRA are integral to orchestrating viral infection programs, maintaining latency and/or persistence, and influencing virus-induced transformation by modulating chromatin dynamics and host immune responses, making them significant targets for therapeutic strategies once fully understood. …”
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Heat shock factor 2 regulates oncogenic gamma-herpesvirus gene expression by remodeling the chromatin at the ORF50 and BZLF1 promoter. by Lorenza Cutrone, Hedvig Djupenström, Jasmin Peltonen, Elena Martinez Klimova, Simona Corso, Silvia Giordano, Lea Sistonen, Silvia Gramolelli

“…While the default infection program for these viruses is latent, sporadic lytic reactivation supports virus dissemination and oncogenesis. …”
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Specific IgA antibodies in the diagnosis of acute brucellosis by Hanan El-Mohammady, Hind Ibrahim Shaheen, John David Klena, Isabelle Antoun Nakhla, Mattew A Weiner, Adam Wilson Armstrong

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Biosynthesis of Ultrasonically Modified Ag-MgO Nanocomposite and Its Potential for Antimicrobial Activity by Wasiu B. Ayinde, Mugera W. Gitari, Munkombwe Muchindu, Amidou Samie

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The epidemiology of bacterial meningitis in the United States during 2008–2023: an analysis of active, laboratory, population-based, multistate surveillance dataResearch in context... by Namrata Prasad, Miwako Kobayashi, Jennifer P. Collins, Amy B. Rubis, Gordana Derado, Miranda J. Delahoy, Daniel C. Payne, Lesley McGee, Sopio Chochua, Henju Marjuki, Lucy A. McNamara, LeAnne M. Fox, Arthur Reingold, Megan Barnes, Susan Petit, Monica M. Farley, Lee H. Harrison, Ruth Lynfield, Jessica Houston, Bridget J. Anderson, Ann Thomas, Keipp H. Talbot, William Schaffner, Adam L. Cohen, Stephanie J. Schrag, Melissa Arvay

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Effectiveness of an Educational Program on Nurses Knowledge about Nosocomial Infection: Case- Control Study by Saad A. Jissir, Huda B. Hassan

“…Recommendation: The study recommends working to application of national program of nosocomial infection program at all health centers and continuous medical educational program for all staff in the health center, and continuous follow up to applying the program to prevent nosocomial infection after admission patients to hospital …”
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Comparison of common acute respiratory infection case definitions for identification of hospitalized influenza cases at a population-based surveillance site in Egypt. by Emily Rowlinson, Lisa Peters, Adel Mansour, Hoda Mansour, Nahed Azazzy, Mayar Said, Sahar Samy, Eman Abbas, Hanaa Abu Elsood, Manal Fahim, Alaa Eid, Erik Reaves, Chris Van Beneden, Sarah Hamid, Sonja Olsen, Julia Fitzner, Erica Dueger

“…Sensitivity, specificity and PPV for influenza identification was compared between the 2014 WHO Severe Acute Respiratory Infection (SARI) definition (fever ≥38°C and cough with onset within 10 days), the 2011 WHO SARI definition (fever ≥38°C and cough with onset within 7 days), the 2006 PAHO SARI definition, the International Emerging Infections Program (IEIP) pneumonia case definition, and the International Management of Childhood Illness (IMCI) case definitions for moderate and severe pneumonia.…”
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Multidrug-resistant Shigella flexneri outbreak affecting humans and non-human primates in New Mexico, USA by Sarah Shrum Davis, Paris Salazar-Hamm, Karen Edge, Tim Hanosh, Jessica Houston, Anastacia Griego-Fisher, Francelli Lugo, Nicholas Wenzel, D’Eldra Malone, Carol Bradford, Kelly Plymesser, Michael Baker, Kurt Schwalm, Sarah Lathrop, Chad Smelser, Darrell L. Dinwiddie, Daryl Domman

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HIV status awareness and associated factors among domestic workers in Kigali, Rwanda by Everest Turatsinze, Alain Favina, Fred Mulisa, Ritah Mukashyaka, Ann Karanja, Deborah Kansiime, Louange Twahirwa Gutabarwa, Peace Kwizera, Aflodis Kagaba, Andrew Gasozi Ntwali, Dan Lutasingwa, Mark Mohan Kaggwa

“…To achieve the 2030 goal of eradicating HIV infection, programs should innovate ways to target this vulnerable group specifically.…”
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92 Prevalence of heteroresistance in urinary Escherichia coli in Metropolitan Atlanta, Georgia by Sarah Blaine, Sarah Kathryn Blaine, Sarah Lohsen, Julia A Van Riel, Madeleine Boulis, Alexandra Rio, D’Ante Gooden, Gillian Smith, David Weiss, Jessica Howard-Anderson, Sarah Satola

“…Methods/Study Population: Clinical urine Escherichia coli isolates from patients in metropolitan Atlanta, Georgia in August 2023 were collected as part of public health surveillance performed by the CDC-funded, Georgia Emerging Infections Program (EIP). Only the first E. coli isolate collected for each patient was included in this study. …”
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Integration of anti-PD-1 antibody into chemotherapeutic regimens improved the outcome of aggressive NK cell leukemia: a single-center retrospective real-world analysis by Kai Shen, Yi Liao, Yang Dai, Jie Ji, Pu Kuang, Zhigang Liu, Liping Xie, Ting Niu, Nenggang Jiang, Hongbing Ma

“…BackgroundAggressive natural killer (NK) cell leukemia (ANKL) is a rare NK cell neoplasm associated with Epstein-Barr virus (EBV) infection. Programmed cell death protein 1 (PD-1) blockade, which is successful in extranodal NK/T-cell lymphoma and EBV-related hemophagocytic lymphohistiocytosis, is considered to have a potential role in managing ANKL.ObjectivesThis study aims to characterize ANKL clinically and evaluate the prognostic impact of anti-PD-1 antibody treatment.MethodsWe retrospectively analyzed the clinical characteristics and treatment regimens of ANKL patients from March 2009 to October 2023 in a single center. …”
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Machine learning approaches to identify neonates and young children at risk for postdischarge mortality in Dar es Salaam, Tanzania and Monrovia, Liberia by Rodrick Kisenge, Todd A. Florin, Cynthia G. Whitney, Michelle Niescierenko, Julia Kamara, Abraham Samma, Evance Godfrey, Chris A. Rees, Readon C. Ideh, Ye-Jeung G. Coleman-Nekar, Hussein K. Manji, Christopher R. Sudfeld, Adrianna L. Westbrook, Claudia R. Morris, Karim P. Manji, Christopher P. Duggan, Rishikesan Kamaleswaran

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