New Insights in Genetic Cholestasis: From Molecular Mechanisms to Clinical Implications by Eva Sticova, Milan Jirsa, Joanna Pawłowska

“…Phenotypic manifestation is highly variable, ranging from progressive familial intrahepatic cholestasis (PFIC)—with onset in early infancy and progression to end-stage liver disease—to a milder intermittent mostly nonprogressive form known as benign recurrent intrahepatic cholestasis (BRIC). …”
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Rapid Spontaneous Resolution of Fibromatosis Colli in a 3-Week-Old Girl by Paolo Adamoli, Piero Pavone, Raffaele Falsaperla, Roberta Longo, Giovanna Vitaliti, Claudio Andaloro, Serra Agostino, Salvatore Cocuzza

“…Fibromatosis colli is an uncommon benign, congenital fibrous tumor or pseudotumor of the sternocleidomastoid muscle that manifests in infancy. In some of these patients tightening of the muscle results in torticollis. …”
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Reconfigurable Intelligent Surfaces Between the Reality and Imagination by Asst. Prof. Haider ALRikabi, Adheed Sallomi, Hasan Khazaal, Ahmed Magdy, Iryna Svyd, IVAN OBOD

“…More study is required before this technology can reach its full potential since it is still in its infancy. Still, RIS is going to be big in the next generation of wireless networks. …”
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Clinical Phenotype of Fucosidosis in Cuba by Víctor Jesús Tamayo Chang, George Alberto Pérez Benítez

“…<br /><strong>Results:</strong> hurleroid facies, neurological and physical development impairment, joint contractures and skeletal deformities were the most frequent clinical manifestations in the 19 diagnosed cases. 84.2 % of patients presented angiokeratoma, and in 52.7 % there was delay in psychomotor development that began in infancy and rapid neurodegeneration, with loss of motor and language skills before the age of five. 42.1 % of patients died between 10 and 20 years of age. …”
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Respiratory Syncytial Virus Infections in Infants Affected by Primary Immunodeficiency by Marcello Lanari, Silvia Vandini, Maria Grazia Capretti, Tiziana Lazzarotto, Giacomo Faldella

“…Respiratory syncytial virus (RSV) is one of the most frequent pathogens during early infancy and the infection is more severe in immunocompromised infants than in healthy infants, as a result of impaired T- and B-cell immune response unable to efficaciously neutralize viral replication, with subsequent increased viral shedding and potentially lethal lower respiratory tract infection. …”
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An Ethnobotanical Study of the Medicinal Plants Used as Anti-Inflammatory Remedies in Gampaha District, Western Province, Sri Lanka by Mayuri Tharanga Napagoda, Thamudi Sundarapperuma, Diroshi Fonseka, Sachinthi Amarasiri, Prabath Gunaratna

“…Although there is a rich reserve of indigenous knowledge of medicinal plants, the preservation and the scientific validation of these claims are still in its infancy. Thus, the study was carried out in one of the administrative areas of Sri Lanka known as Gampaha District to assess the significance and contribution of medicinal plants in inflammatory conditions. …”
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Nephrogenic Syndrome of Inappropriate Antidiuresis by D. Morin, J. Tenenbaum, B. Ranchin, T. Durroux

“…This latter recently described disease may be diagnosed from infancy to adulthood, as some carriers remain asymptomatic for many years. …”
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New trends of additive manufacturing using materials based-on natural fibers and minerals : A systematic review by Joao Ribeiro, Manuel Rodríguez-Martín, Joaquín Barreiro, Ana Fernández-Abia, Roberto García-Martín, Joao Rocha, Susana Martínez-Pellitero

“…Polymeric materials based on natural fibers and minerals are currently being researched and their development is still in its infancy but is expected to increase in the coming years (being nowadays a hot topic). …”
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A Newborn with Cleft Palate Associated with PTEN Hamartoma Tumor Syndrome by Ulf Nestler, Daniel Gräfe, Vincent Strehlow, Robin-Tobias Jauss, Andreas Merkenschlager, Annika Schönfeld, Florian Wilhelmy

“…<b>Conclusion</b>: Since the amount of prospective data remains limited, and the estimation of tumor risk during infancy and adulthood is very difficult, we advocate for early and broad genetic testing in suspected cases, to gain more insights into this rare disease and allow for better counseling for patients and their families.…”
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Resolving Covid-19 with Blockchain and AI by Suyogita Singh, Satya Bhushan Verma

“…In that review, many potential blockchain applications were discovered; however, the majority of them were still in their infancy, and it couldn’t yet be predicted how they could contribute to the fight against COVID-19 through the use of platforms, access kinds, and consensus algorithms. …”
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American alligators (Alligator mississippiensis) as wetland ecosystem carbon stock regulators by Christopher M. Murray, Tyler Steven Coleman, Wray Gabel, Ken W. Krauss

“…However, quantified associations between vertebrate biota and carbon sequestration within ecosystems are in their infancy and have been incidental, given that microbial trophic levels are thought to drive nutrient dynamics. …”
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A Precocious Cerebellar Ataxia and Frequent Fever Episodes in a 16-Month-Old Infant Revealing Ataxia-Telangiectasia Syndrome by Luigi Nespoli, Annapia Verri, Silvia Tajè, Francesco Paolo Pellegrini, Maddalena Marinoni

“…Ataxia-telangiectasia (AT) is the most frequent progressive cerebellar ataxia in infancy and childhood. Immunodeficiency which includes both cellular and humoral arms has variable severity. …”
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Improving Physical Activity mHealth Interventions: Development of a Computational Model of Self-Efficacy Theory to Define Adaptive Goals for Exercise Promotion by Dario Baretta, Fabio Sartori, Andrea Greco, Marco D’Addario, Riccardo Melen, Patrizia Steca

“…However, research on these topics is still at its infancy. The current paper presents a smartphone application and wearable device system called Muoviti! …”
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ARV1 p.Gln62Ter, a novel mutation linked to developmental and epileptic encephalopathy-38 by Mostafa Neissi, Ayoob Radhi Al-Zaalan, Misagh Mohammadi-Asl, Mojdeh Roghani, Javad Mohammadi-Asl, Kamele Jorfi

“…Despite conventional anti-seizure drugs, seizures persisted from infancy. Tragically, her elder sibling with identical symptoms succumbed to the condition at 11 months. …”
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More than just a number: the gut microbiota and brain function across the extremes of life by Nathan D. Nuzum, Clara Deady, Sarah Kittel-Schneider, John F. Cryan, Siobhain M. O'Mahony, Gerard Clarke

“…Understanding the interrelationship between the gut microbiota and host physiology, although still in its relative infancy, has taken important steps forward over the past decade. …”
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Developmental inequity and the impact of pesticide exposure on gut and brain health in developing nations – a Brazilian perspective by Jessica Gama, Bianca Cruz Neves, Antonio Pereira

“…The effects of pesticides on developmental trajectory are particularly concerning during vulnerable periods of heightened cortical neuroplasticity over prenatal, infancy, and adolescent stages. This article also explores the unequal regulatory landscape for pesticides, emphasizing the disparities between more-regulated and less-regulated regions. …”
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SHOX and sex difference in height: a hypothesis by Tsutomu Ogata, Atsushi Hattori, Maki Fukami

“…In this regard, previous studies have revealed that (1) distribution of the mean adult heights in subjects with disorders accompanied by discordance between sex chromosome complement and bioactive sex steroids and in control subjects (the British height standards) indicates that, of the ~12.5 cm of sex difference in the mean adult height, ~9 cm is accounted for by the difference in the sex chromosome complement and the remaining ~3.5 cm is explained by the dimorphism in sex steroids (primarily due to the growth-promoting effect of gonadal androgens); (2) according to the infancy-childhood-puberty growth model, the sex difference in the childhood growth function produces height differences of ~1 cm in childhood and 8–10 cm at 18–20 years of age, whereas the sex difference in the pubertal growth function yields height difference of ~4.5 cm at 18–20 years of age; and (3) SHOX expression and methylation analyses using knee cartilage tissues and cultured chondrocytes have shown lower SHOX expression levels in female samples than in male samples and methylation patterns consistent with partial spreading of X-inactivation affecting SHOX in female samples. …”
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Cystic Lymphangioma of the Greater Omentum: A Case of Partial Spontaneous Regression and Review of the Literature by Haraesh Maranna, Lovenish Bains, Pawan Lal, Rahul Bhatia, Mohd Yasir Beg, Pritesh Kumar, Varuna Mallya

“…Cystic lymphangiomas have an incidence of 1/20000 at infancy and 1/100000 to 1/250000 of hospital admissions in adults, and the female-to-male ratio is 2 : 1. …”
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Perceptions and attitudes towards AI among trainee and qualified radiologists at selected South African training hospitals by Ayanda I. Nciki, Linda T. Hlabangana

“…Conclusion: The findings suggest AI in radiology is in its infancy, with a need for educational programmes to upskill radiologists. …”
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Complementary feeding and the early origins of obesity risk: a study protocol by Daniel D Reidpath, Ireneous N Soyiri, Naleena Devi Muniandy, Pascale A Allotey

“…Studies show that nutrition during early infancy may contribute to later obesity. Hence, this study is designed to determine if the variation in complementary feeding practices poses a risk for the development of obesity later in life. …”
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