The Immune Response to Tumors as a Tool toward Immunotherapy by F. Pandolfi, R. Cianci, D. Pagliari, F. Casciano, C. Bagalà, A. Astone, R. Landolfi, C. Barone

“…More recently with the remarkable mushroom of immunology, newer tools became available, resulting in the novel possibility to attack cancer with the specificity of the immune system. Herein we will review some of the recent achievement of immunotherapy in such aggressive cancers as melanoma, prostatic cancer, colorectal carcinoma, and hematologic malignancies. …”
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The Effects of MicroRNAs on Key Signalling Pathways and Epigenetic Modification in Fibroblast-Like Synoviocytes of Rheumatoid Arthritis by Wenming Hong, Pengying Zhang, Xinming Wang, Jiajie Tu, Wei Wei

“…Emerging evidence shows that miRNAs play crucial roles in controlling and modulating immune system-related diseases. This review focuses on the role played by miRNAs in fibroblast-like synoviocytes (FLS), which is a key cellular component within synovia, during the establishment and maintenance of rheumatoid arthritis (RA), a systemic inflammatory autoimmune disease. …”
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Fluconazole-Like Compounds as Potential Antifungal Agents: QSAR, Molecular Docking, and Molecular Dynamics Simulation by Farnaz Salehi, Leila Emami, Zahra Rezaei, Soghra Khabnadideh, Behnaz Tajik, Razieh Sabet

“…Today, fungal infection has become more common disease especially in some cases, such as AIDS, cancer, and organ transplant which the immune system is suppressed. On the other hand, due to the increasing resistance to current antifungal drugs, more and more options for design of novel more efficient compounds with higher resistance are needed. …”
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From the Role of Microbiota in Gut-Lung Axis to SARS-CoV-2 Pathogenesis by Sara Ahmadi Badi, Samira Tarashi, Abolfazl Fateh, Pejman Rohani, Andrea Masotti, Seyed Davar Siadat

“…Therefore, the importance of the gut microbiota composition in the lung immune system and ACE2 expression could be valuable to provide optimal therapeutic approaches for SARS-CoV-2 and to preserve the symbiotic relationship of the microbiota with the host.…”
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Bile Acids and the Microbiome: Making Sense of This Dynamic Relationship in Their Role and Management in Crohn’s Disease by Aditi Kumar, Hafid O. Al-Hassi, Helen Steed, Oliver Phipps, Matthew J. Brookes

“…Current research suggests that there is a strong interplay between the dysregulated microbiota, bile acid metabolism, and the mucosal immune system that can result in a changed immunological function, triggering the inflammatory response in Crohn’s disease. …”
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The impact of innate immune response on the efficacy of oncolytic viruses by Kirill N. Trachuk, Nikolai B. Pestov, Yulia K. Biryukova, Nadezhda M. Kolyasnikova

“…Stimulation of innate immune cells by an oncolytic virus can initiate an adaptive antitumor immune response, yet at the same time, the antiviral mechanisms of the immune system can limit the spread of the virus, thereby reducing its effectiveness. …”
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T Lymphocyte Autoreactivity in Inflammatory Mechanisms Regulating Atherosclerosis by Elisabetta Profumo, Brigitta Buttari, Luciano Saso, Raffaele Capoano, Bruno Salvati, Rachele Riganò

“…Both cells of the innate and the acquired immune system, particularly monocytes and T lymphocytes, are implicated in the atherogenic process, producing different cytokines with pro- and anti-inflammatory effects. …”
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Human TCR repertoire in cancer by Lin Chen, Yuan Hu, Bohao Zheng, Limei Luo, Zhenzhen Su

“…Abstract Background T cells, the “superstar” of the immune system, play a crucial role in antitumor immunity. …”
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Crotoxin Isolated from Crotalus durissus terrificus Venom Modulates the Functional Activity of Dendritic Cells via Formyl Peptide Receptors by A. P. Freitas, B. C. Favoretto, P. B. Clissa, S. C. Sampaio, E. L. Faquim-Mauro

“…The Crotalus durissus terrificus rattlesnake venom, its main toxin, crotoxin (CTX), and its crotapotin (CA) and phospholipase A2 (CB) subunits modulate the immune system. Formyl peptide receptors (FPRs) and lipoxin A4 (LXA4) are involved in CTX’s effect on macrophages and neutrophils. …”
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Hepatitis C Virus Infection and Mixed Cryoglobulinemia by Gianfranco Lauletta, Sabino Russi, Vincenza Conteduca, Loredana Sansonno

“…Its persistence represents a continuous stimulus for host immune system with production of circulating immune complexes (ICs), one-third of them with cryoprecipitate property. …”
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Human Endogenous Retroviruses and Their Putative Role in Pathogenesis of Alzheimer’s Disease, Inflammation, and Senescence by Patrycja Kozubek, Julia Kuźniar, Magdalena Czaja, Hanna Sitka, Urszula Kochman, Jerzy Leszek

“…Additionally, some molecules derived from HERVs may stimulate the immune system. Recently research has been focused on the effect of human endogenous retroviruses on the development of neurodegenerative diseases, including Alzheimer’s disease (AD), which is the most common cause of dementia. …”
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F4/80+ Host Macrophages Are a Barrier to Murine Embryonic Stem Cell-Derived Hematopoietic Progenitor Engraftment In Vivo by Heather L. Thompson, Nico van Rooijen, Bryce T. McLelland, Jennifer O. Manilay

“…Understanding how embryonic stem cells and their derivatives interact with the adult host immune system is critical to developing their therapeutic potential. …”
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Acknowledging and addressing real-world challenges to treating immune-related adverse events by Bonnie L Bermas, Mitchell S von Itzstein, David E Gerber, Alexa Meara

“…These autoimmune toxicities are heterogeneous, unpredictable, and reflect a disease state resulting from a change in the immune system of patients. This contrasts with the typical acute nature of toxicities from chemotherapy and molecularly targeted oncology therapies. …”
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Effect of innate and induced immunity on infectious bursal disease pathogenesis by A. N. Semina

“…The infectious bursal disease virus (IBDV) affects chicken’s immune system in a comprehensive and integrated manner thus destructing B-lymphocytes, attracting T-cells and activating macrophages. …”
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Improving gut microbiome through diet rich in dietary fibre and polyphenols: The case for orange peels by Ayokunle Olubode Ademosun, Olufunke Florence Ajeigbe, Mary Tosin Ademosun, Omodesola Oluwafisayo Ogunruku, Ganiyu Oboh

“…The gut microbiota is crucial for various physiological functions, such as nutrient absorption, immune system enhancement, gut structural integrity, and detoxifying harmful substances. …”
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Maternal–Foetal Effects of Exposure to Bisphenol A: Outcomes and Long-Term Consequences by Henrique Eloi Costa, Ines Medeiros, Melissa Mariana, Elisa Cairrao

“…Specifically, BPA exposure affects the immune system of the offspring and promotes the development of respiratory diseases, including asthma and wheezing. …”
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Targeting T-Cell Activation for Malaria Immunotherapy: Scoping Review by Balsa Nobility Gustifante, Shafia Khairani, Nisa Fauziah, Silvita Fitri Riswari, Afiat Berbudi

“…The genetic variability of <i>Plasmodium</i> proteins complicates the development of long-lasting immunity, as it impedes the human immune system’s ability to sustain effective responses. …”
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Methylation Marks of Blood Leukocytes of Native Hucul Mares Differentiated in Age by T. Ząbek, E. Semik-Gurgul, T. Szmatoła, A. Gurgul, A. Fornal, M. Bugno-Poniewierska

“…Advanced age is often associated with a decrease in body condition, dysfunction of immune system, and late-onset disorders. Due to this, the search for new solutions in the prevention and treatment of pathological conditions of the advanced age of horses is desirable. …”
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Pharmacological inhibition of key metabolic pathways attenuates Leishmania spp infection in macrophages. by Elaine Carvalho de Oliveira, Rafael Tibúrcio, Gabriela Duarte, Amanda Lago, Léon de Melo, Sara Nunes, Gustavo Gastão Davanzo, Ana Júlia Martins, Bruno Vinagre Ribeiro, Deborah Mothé, Juliana B P Menezes, Patrícia Veras, Natalia Tavares, Pedro M Moraes-Vieira, Cláudia Ida Brodskyn

“…Macrophages represent a fundamental component of the innate immune system that play a critical role in detecting and responding to pathogens as well as danger signals. …”
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Evaluation of antibiofilm activity of Thymus syriacus essential oil against clinically isolated MDR bacteria by Basem Battah, Anas Rajab, Lama Shbibe, Jagjit Singh Dhaliwal, Khang Wen Goh, Long Chiau Ming, Yaman Kassab, Abdelhakim Bouyahya, Mahibub Mahahamadsa Kanakal, Chadi Soukkarieh

“…Bacteria can use biofilm as a mechanism of resistance against antibacterial drugs and avoid the immune system. The aim of this study was to evaluate the antibacterial activity of Thymus syriacus (T. syriacus) essential oil in a solid and liquid medium and to study its antibiofilm formation activity. …”
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