In vitro studies on the immunomodulatory effects of fulvic acid extract from palm oil empty fruit bunch (OPEFB) by Dimarwanita Firda, Mariya Silmi, Nur Annisa Dewi Fitria, Latisya Silva, Faramitha Yora, Goenadi Didiek Hadjar

“…With an increasing need for sustainable natural therapies, FA has shown promise in treating degenerative diseases by modulating immune responses. The research focused on assessing the immunomodulatory effects of FA by analysing its impact on cytokine production. …”
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Susceptibility of Porphyromonas gingivalis and Streptococcus mutans to Antibacterial Effect from Mammea americana by Alejandra Herrera Herrera, Luis Franco Ospina, Luis Fang, Antonio Díaz Caballero

“…These microorganisms trigger inflammatory and immune responses in the host. Currently, medicinal plants are treatment options for these oral diseases. …”
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Targeting SRSF1 improves cancer immunotherapy by dually acting on CD8+T and tumor cells by Gui-Qi Zhu, Zheng Tang, Tian-Hao Chu, Biao Wang, Shi-Ping Chen, Chen-Yang Tao, Jia-Liang Cai, Rui Yang, Wei-Feng Qu, Yi Wang, Qian-Fu Zhao, Run Huang, Meng-Xin Tian, Yuan Fang, Jun Gao, Xiao-Ling Wu, Jian Zhou, Wei-Ren Liu, Zhi Dai, Ying-Hong Shi, Jia Fan

“…The small-molecule inhibitor TN2008 targets SRSF1, boosting antitumor immune responses and improving immunotherapy effectiveness in mouse models. …”
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The TIR Domain Containing Locus of Enterococcus faecalis Is Predominant among Urinary Tract Infection Isolates and Downregulates Host Inflammatory Response by Thomas Daniel Kraemer, Orlando Daniel Quintanar Haro, Eugen Domann, Trinad Chakraborty, Svetlin Tchatalbachev

“…When transiently expressed in cultured eukaryotic cells, TcpF caused suppression of TLR2-dependent NF-κB activation suggesting for TcpF a role as a factor in E. faecalis that benefits colonization by modulating the host’s immune responses.…”
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Cytosolic DNA composition is determined by genomic instability mechanism and regulates dendritic cell-mediated anti-tumor immunity by Shayla R. Mosley, Angie Chen, David N.W. Doell, Siwon Choi, Courtney Mowat, Felix Meier-Stephenson, Vanessa Meier-Stephenson, Kristi Baker

“…Summary: Patients with colorectal cancers (CRCs) that have microsatellite instability (MSI) (MSI CRCs) face a better prognosis than those with the more common chromosomal instability (CIN) subtype (CIN CRCs) due to improved T cell-mediated anti-tumor immune responses. Previous investigations identified the cytosolic DNA (cyDNA) sensor STING as necessary for chemokine-mediated T cell recruitment in MSI CRCs. …”
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Role of E-cadherin in epithelial barrier dysfunction: implications for bacterial infection, inflammation, and disease pathogenesis by Peter Lialios, Peter Lialios, Stella Alimperti, Stella Alimperti

“…Lately, its pleiotropic role beyond barrier function, including its involvement in immune responses, has become more evident. Herein, we delve into the intricate relationship between (dys)regulation of epithelial homeostasis and the versatile functionality of E-cadherin, describing complex mechanisms that underlie barrier integrity and disruption in disease pathogenesis such as bacterial infection and inflammation, among others. …”
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The Role of Protein Modifications of T-Bet in Cytokine Production and Differentiation of T Helper Cells by Sera Oh, Eun Sook Hwang

“…Therefore, T-bet is crucial for the development and coordination of both innate and adaptive immune responses. To fulfill these multiple roles, T-bet undergoes several posttranslational protein modifications, such as phosphorylation at tyrosine, serine, and threonine residues, and ubiquitination at lysine residues, which affect lineage commitment during Th cell differentiation. …”
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The Impact of PPARγ Genetic Variants on IBD Susceptibility and IBD Disease Course by Jessica Mwinyi, Christa Grete-Wenger, Jyrki J. Eloranta, Gerd A. Kullak-Ublick

“…PPARγ is a nuclear receptor that regulates numerous pathways including cytokine expression and immune responses and plays an important role in controlling colon inflammation. …”
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Diethyldithiocarbamate-copper complex ignites the tumor microenvironment through NKG2D-NKG2DL axis by Daciana C. Dumut, Daciana C. Dumut, Marian Hajduch, Marian Hajduch, Amanda M. Zacharias, Qingling Duan, Qingling Duan, Ivo Frydrych, Zuzana Rozankova, Zuzana Rozankova, Miroslav Popper, Miroslav Popper, Dusan Garic, Radu Alexandru Paun, Radu Alexandru Paun, Amanda Centorame, Amanda Centorame, Juhi Shah, Martin Mistrik, Martin Mistrik, Petr Dzubak, Petr Dzubak, Juan B. De Sanctis, Juan B. De Sanctis, Danuta Radzioch, Danuta Radzioch, Danuta Radzioch, Danuta Radzioch

“…CuET is shown to convert immunologically inactive tumors into hotbeds of antitumor immune responses, marked by increased lymphocyte infiltration, heightened cytotoxicity of natural killer (NK) and T cells, and enhanced non-self recognition by lymphocytes. …”
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Claudin-11 regulates immunological barrier formation and spermatogonial proliferation through stem cell factor by Taichi Sugawara, Kayoko Sonoda, Nattapran Chompusri, Kazuhiro Noguchi, Seiji Okada, Mikio Furuse, Tomohiko Wakayama

“…This suggests that adaptive immune responses to spermatogenic cells are not a cause of defective spermatogenesis in Cldn11-deficient mice. …”
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Aptamers: A Feasible Technology in Cancer Immunotherapy by M. M. Soldevilla, H. Villanueva, F. Pastor

“…A variety of aptamers described to date have been shown to be reliable in modulating immune responses against cancer by either blocking or activating immune receptors. …”
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Identification and Characterization of the <i>LecRLKs</i> Gene Family in Maize, and Its Role Under Biotic and Abiotic Stress by Xiangbo Yang, Ziqi Chen, Jianyu Lu, Xuancheng Wei, Yanying Yao, Wendi Lv, Jiarui Han, Jianbo Fei

“…It can rapidly respond to both biotic and abiotic stresses while mediating mechanisms of plant immune responses. This study represents the first identification of the LecRLK family genes in maize. …”
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Immune Aspects and Myometrial Actions of Progesterone and CRH in Labor by Nikolaos Vrachnis, Fotodotis M. Malamas, Stavros Sifakis, Panayiotis Tsikouras, Zoe Iliodromiti

“…The mechanisms related to their effect differ between humans and other species, thus, despite extensive research, many questions remain to be answered regarding their mediation in human labor. Immune responses to progesterone and CRH are important for labor. …”
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Transcriptomics-based investigation of resistance differences to swine fever between large white pigs and min pigs by Jia Li, Deming Ren, Xiangxu Meng, Yiyun He, Lixian Wang, Xihui Sheng, Ligang Wang

“…This heightened immune responsiveness could contribute to the observed differences in disease resistance between Min pigs and Large White pigs.…”
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Probiotics in the Modern World by Y. P. Uspenskiy, Y. A. Fominykh, K. N. Nadzhafova, S. V. Polyushkin

“…Alike normal microflora, probiotic strains incorporate into general metabolism by mediating a spectrum of functions, e.g. maintaining colonisation resistance, nutrient metabolism, supplying the host with vital metabolites, regulation of local and adaptive immune responses, enhancing the intestinal barrier. Probiotics are applied in various diseases associated with general imbalances of the organism. …”
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Secretory Products of Trichinella spiralis Muscle Larvae and Immunomodulation: Implication for Autoimmune Diseases, Allergies, and Malignancies by Ljiljana Sofronic-Milosavljevic, Natasa Ilic, Elena Pinelli, Alisa Gruden-Movsesijan

“…Those products can successfully modulate parasite-specific immune responses as well as responses to unrelated antigens (either self or nonself in origin), providing an anti-inflammatory milieu and maintaining homeostasis. …”
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Immunogenicity of Pfizer mRNA COVID-19 Vaccination Followed by J&J Adenovirus COVID-19 Vaccination in Two Patients with Chronic Lymphocytic Leukemia by Zoe L. Lyski, Myung Sun Kim, David Xthona Lee, David Sampson, Hans-Peter Raué, Vikram Raghunathan, Debbie Ryan, Amanda E. Brunton, Mark K. Slifka, William B. Messer, Stephen E. Spurgeon

“…SARS-CoV-2 specific immune responses, including antibodies and memory B-cells, CD4 and CD8 T-cells were assessed prior to vaccination, as well as postinitial vaccination series and post-third dose in two subjects. …”
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Gut-Lung Microbiota in Chronic Pulmonary Diseases: Evolution, Pathogenesis, and Therapeutics by Chang Yi Shi, Chen Huan Yu, Wen Ying Yu, Hua Zhong Ying

“…The imbalance of microbiota is usually linked to the aberrant immune responses and inflammation, which eventually promotes the occurrence and development of respiratory diseases. …”
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Adoptive cell transfer of piezo-activated macrophage rescues immunosuppressed rodents from life-threating bacterial infections by Xiaoyi Liu, Wenxiu Xu, Junkun Feng, Ying Wang, Kai Li, Yi Chen, Wenjun Wang, Weiwei Zhao, Shaohua Ge, Jianhua Li

“…Our study thus highlights the potential application of catalytic nanoparticles as a promising alternative to conventional infection treatment to effectively modulate the innate immune responses and to engineer macrophages for immunotherapy purposes.…”
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The gut microbiome, immune modulation, and cognitive decline: insights on the gut-brain axis by Ruyi Zhang, Ruyi Zhang, Ning Ding, Xicui Feng, Wenli Liao

“…Research indicates that gut bacteria produce metabolites, including short-chain fatty acids (SCFAs), which affect mucosal immunity, antigen presentation, and immune responses, thereby influencing cognitive functions. …”
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