Role of interleukin-15 and interleukin-18 in the secretion of sIL-6R and sgp130 by human neutrophils by E. Jablonska, M. Marcinczyk

“…Background: Available data indicate that neutrophils (PMN) produce a wide range of cytokines with the potential to modulate immune response. Recent investigation have shown that interleukin (IL)-15 and IL-18 potentiated several functions of normal neutrophils. …”
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Inflammatory bowel diseases during the COVID-19 pandemic by Edyta Derda, Edyta Szymańska, Magda Sokolek, Jarosław Kierkuś

“…Inflammatory bowel diseases (IBD) are chronic, incurable conditions of digestive system with unknown aetiology, but one of the causes is disordered immune response. Medical therapies most frequently used in IBD are immune suppressing or modifying with the rising use of biologic treatment. …”
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Identification of T and В lymphocytes in chickens and their subpopulations byflowcytofluorometric analysis using flow cytometer BD FACSVerse™ by M. A. Volkova, Ir. A. Chvala

“…Antibody panels for immunophenotyping lymphocytes when testing chicken cell mediated immune response were selected and tested. They enable to determine a relative number of T- and B-lymphocytes, T-helpers and T-cytotoxic cell populations in blood and chicken lymphoid organs. …”
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Resistance mechanisms matter in SIR models by Timothy C. Reluga, Jan Medlock

“…We compare four SIR-style modelsdescribing behavioral or immunological disease resistance thatmay be both partial and temporaryin parameter regions feasible for interpandemic influenza.For the models studied, backward bifurcations andbistability may occur in contexts where resistance isdue to behavior change, but they do not occur when resistanceoriginates from an immune response. Care must be exercisedto ensure that modeling assumptions about resistance areconsistent with the biological mechanisms under study.…”
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Transcriptomic profiles of monocyte-derived macrophages exposed to SARS-CoV-2 VOCs reveal immune-evasion escape driven by delta by Alessia Gallo, Josè Camilla Sammartino, Roberta Vazzana, Roberto Giambruno, Claudia Carcione, Nicola Cuscino, Salvatore Castelbuono, Vitale Miceli, Matteo Bulati, Daniele Lilleri, Irene Cassaniti, Pier Giulio Conaldi, Fausto Baldanti

“…Our data suggest an evolution of VOC in modulating the host immune response, with a strong change in pace beginning with the advent of the Delta variant. …”
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Measles and Pregnancy: Immunity and Immunization—What Can Be Learned from Observing Complications during an Epidemic Year by Rosalia Ragusa, Armando Platania, Mario Cuccia, Gaetano Zappalà, Gabriele Giorgianni, Placido D’Agati, Maria Alessandra Bellia, Marina Marranzano

“…As measles causes a dysregulation of the entire immune system, we describe immunological variations and how immune response mechanisms can lead to adverse pregnancy outcomes. …”
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Liver HLA-E Expression Is Associated with Severity of Liver Disease in Chronic Hepatitis C by Roberta C. Araújo, Fabricio C. Dias, Bruna C. Bertol, Deisy M. Silva, Patrícia H. Almeida, Andreza C. Teixeira, Fernanda F. Souza, Marcia G. Villanova, Leandra N. Z. Ramalho, Eduardo A. Donadi, Ana L. C. Martinelli

“…Hepatitis C virus (HCV) can escape from innate and adaptive immunity, making the immune response ineffective. Human leukocyte antigen E (HLA-E) might regulate the antiviral function of immune response and contribute to the persistence of HCV and the severity of liver disease. …”
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Translating Unconventional T Cells and Their Roles in Leukemia Antitumor Immunity by Nilberto Dias de Araújo, Fábio Magalhães Gama, Mateus de Souza Barros, Thaís Lohana Pereira Ribeiro, Fabíola Silva Alves, Lilyane Amorim Xabregas, Andréa Monteiro Tarragô, Adriana Malheiro, Allyson Guimarães Costa

“…Recently, cell-mediated immune response in malignant neoplasms has become the focus in immunotherapy against cancer. …”
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Unraveling the transcriptomic effects of leucine supplementation on muscle growth and performance in basketball athletes. by Sinan Wang, Weishuai Guo, Rui Dong

“…Identified DEGs enriched in pathways related to immune response, cytokine production, and cell adhesion. …”
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Circulating Th1, Th2, Th17, Treg, and PD-1 Levels in Patients with Brucellosis by Rongjiong Zheng, Songsong Xie, Qiong Zhang, Ling Cao, Shaniya Niyazi, Xiaobo Lu, Lihua Sun, Yan Zhou, Yuexin Zhang, Kai Wang

“…Brucella is an intracellular infection bacterium; the pathogenesis of Brucella and chronicity of infection may be related to the immune response of T cells. T lymphocytes mainly participate in cellular immune response. …”
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Effects of Enterocytozoon hepatopenaei infection on intestinal immune defense and physiological processes of Penaeus vannamei by Zheng Cao, Chuanyu He, Zhipeng Yin, Caiyi Chen, Fan Li, Dongchun Yan, Ting Li, Linrui Chang, Lingjun Si

“…Concurrently, EHP infection can trigger intestinal immune response, and the expression of key immune genes like Toll, myeloid differentiation factor, anti-lipopolysaccharide factor, and Relish was significantly enhanced, while the expression of IMD and alkaline phosphatase was suppressed. …”
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Antibody and serum bactericidal response to Burkholderia pseudomallei in acute localized and septicemic melioidosis cases with diabetes mellitus by Sraboni Mazumder, Md. Shariful Alam Jilani, Lovely Barai, KM Shahidul Islam

“…Background and objectives: Melioidosis, caused by the gram-negative bacillus Burkholderia pseudomallei, is a major cause of fatal community acquired infection in diabetic patients. Protective immune response in human melioidosis is not clearly understood yet. …”
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Serum Levels of LL-37 and Inflammatory Cytokines in Plaque and Guttate Psoriasis by Young Ji Hwang, Ho Jung Jung, Min Jung Kim, Nam Kyung Roh, Jae Wook Jung, Yang Won Lee, Yong Beom Choe, Kyu Joong Ahn

“…It is assumed that the plaque phenotype of psoriasis is associated with T helper (Th) 1 immune response activation, while the guttate phenotype is associated with the Th17 immune response. …”
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Epicardially Placed Bioengineered Cardiomyocyte Xenograft in Immune-Competent Rat Model of Heart Failure by Ikeotunye Royal Chinyere, Pierce Bradley, Joshua Uhlorn, Joshua Eason, Saffie Mohran, Giuliana G. Repetti, Sherry Daugherty, Jen Watson Koevary, Steven Goldman, Jordan J. Lancaster

“…However, the durability of effect, immune response, and in vitro properties of the tissue graft remained uncharacterized. …”
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After Treatment Decrease of Bone Marrow Tregs and Outcome in Younger Patients with Newly Diagnosed Acute Myeloid Leukemia by Mario Delia, Paola Carluccio, Anna Mestice, Roberta Frappampina, Francesco Albano, Giorgina Specchia, Pellegrino Musto

“…In particular, immune suppressive regulatory T cells (Tregs) may contribute to this defective antileukemic immune response, being recruited by bone marrow leukemic cells to evade immune surveillance. …”
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A meta-analysis of whole blood transcriptome reveals genes associated with increased neutrophil activity and T cell suppression in sepsis by T. N. Shruthi, Anbazhagan Kolandaswamy, Prabakara Somanna

“…Down-regulated genes (FCERIA, IL7R, CCR7, CX3CR1, CD3G, CD40LG, CD247, CD3E, and GZMK) were associated with adaptive immune response, T cell function, and antigen processing and presentation. …”
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Sjögren’s Syndrome: Concerted Triggering of Sicca Conditions by Zygmunt Mackiewicz, Justyna Mażul, Ieva Narkevičiūtė, Irena Dumalakienė, Irena Butrimienė, Rita Vilienė, Indrė Stankevičienė, Diana Mieliauskaitė

“…Immunohistochemical analysis of immune response to the suggested silent persistence of mumps virus in the minor labial salivary gland biopsies and flow cytometric analysis of blood cells was done. …”
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Characterization and functional analysis of chicken hnRNP protein by Ke Wang, Manzi Huang, Qinghua Zeng, Huansheng Wu

“…While the role of hnRNP proteins in modulating interferon signaling and virus replication in mammals has been extensively studied, the impact of chicken hnRNPs on innate immune response and Infectious Bursal Disease Virus (IBDV) replication remains largely unexplored. …”
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Antibody response to Plasmodium vivax in the context of Epstein-Barr virus (EBV) co-infection: A 14-year follow-up study in the Amazon rainforest. by Luiz F F Guimarães, Bárbara A Rodrigues, Michelle H F Dias, Matheus G Barcelos, Maria F A Nascimento, Sâmick L Moreira-Nascimento, Sofia L Afonso, Barbara G S Abreu, Jaap M Middeldorp, Francis B Ntumngia, John H Adams, Camila Fabbri, Stefanie Lopes, Cor J F Fernandes, Flora S Kano, Luzia H Carvalho

“…Regardless of the malaria transmission period, the results demonstrated that one or multiple episodes of EBV-DNAemia did not influence the longevity of DBPII immune responses to both strain-specific (Sal-1) or strain-transcending (DEKnull-2) antibodies. …”
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Immunogenic Targets for Specific Immunotherapy in Multiple Myeloma by Lu Zhang, Marlies Götz, Susanne Hofmann, Jochen Greiner

“…These antigens are expressed in a tumor-specific or tumor-restricted pattern, are able to elicit immune response, and thus could serve as targets for immunotherapy. …”
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