Gingipains protect Porphyromonas gingivalis from macrophage-mediated phagocytic clearance. by Magdalena Widziolek, Anna Mieszkowska, Magdalena Marcinkowska, Bartlomiej Salamaga, Justyna Folkert, Krzysztof Rakus, Magdalena Chadzinska, Jan Potempa, Graham P Stafford, Tomasz K Prajsnar, Craig Murdoch

“…Pg produce aggressive proteolytic virulence factors termed gingipains which not only provide nutrients necessary for bacterial growth, but also subvert the host immune response, facilitating bacterial survival. Using transgenic zebrafish with fluorescently labelled macrophages and neutrophils, the role of gingipains in bacterial survival and interaction with phagocytes during systemic and local infection was examined. …”
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Probiotics Can Boost the Antitumor Immunity of CD8+T Cells in BALB/c Mice and Patients with Colorectal Carcinoma by Jie Mao, Shu-Ze Zhang, Peng Du, Zhi-Bin Cheng, Huan Hu, Shi-Yao Wang

“…The aim of the study is to verify antitumor immune response of probiotics in patients with colorectal carcinoma and to explore its mechanism. …”
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Association of the rs562556 PCSK9 Gene Polymorphism with Reduced Mortality in Severe Malaria among Malian Children by Olesya Fedoryak, Charles Arama, Issa Diarra, Bouréma Kouriba, Michel Chrétien, Majambu Mbikay

“…Studies are needed to determine whether PCSK9 inactivation promotes a protective immune response to malaria infection.…”
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Synergistic impacts of propargite exposure and deformed wing virus infection on the health of western honey bees by Chia-Yang Lin, Yu-Chun Lin, Yun-Heng Lu, Shiang-Jiuun Chen, Yu-Hsien Lin, Yao-Kuang Tseng, Yu-Tzu Lin, Yueh-Lung Wu, Rong-Nan Huang

“…The administration of DWV alone boosted the expression of immune response genes, whereas acaricide alone did not significantly affect the expression of detoxification genes. …”
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Maternal Serum Cytokine Concentrations in Healthy Pregnancy and Preeclampsia by Toni Spence, Philip J. Allsopp, Alison J. Yeates, Maria S. Mulhern, J. J. Strain, Emeir M. McSorley

“…The maternal immune response is essential for successful pregnancy, promoting immune tolerance to the fetus while maintaining innate and adaptive immunity. …”
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NLRP12/C1qA positive feedback in tumor-associated macrophages regulates immunosuppression through LILRB4/NF-κB pathway in lung adenocarcinoma by Jiaxin Yin, Yuxiao Song, Yang Fu, Jun Wang, Zhimin Zhang, Shasha Ruan, Gaoli Liu, Bicheng Zhang

“…Abstract The anti-tumor immune response is greatly hindered by the protumor polarization of tumor-associated macrophages (TAMs). …”
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Identification of Potential Biomarkers for Coronary Artery Disease Based on Cuproptosis by Bohong Zhang, Mingliang He

“…By differential expression analysis, we obtained 10 differentially expressed CRGs (DE-CRGs), which were associated with copper ion response, immune response, and material metabolism. Based on the 10 DE-CRGs, we furtherly performed LASSO analysis and SVM-RFE analysis and identified 5 DE-CRGs as marker genes, including F5, MT4, RNF7, S100A12, and SORD, which had an excellent diagnostic performance. …”
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Molecular Networks Involved in the Immune Control of BK Polyomavirus by Eva Girmanova, Irena Brabcova, Jiri Klema, Petra Hribova, Mariana Wohlfartova, Jelena Skibova, Ondrej Viklicky

“…The gene expression profiles of 90 target genes known to be associated with immune response were evaluated in kidney graft biopsy material using TaqMan low density array. …”
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Toll-Like Receptors 2, 4, and 7, Interferon-Gamma, Interleukin 10, and Programmed Death Ligand 1 Transcripts in Leishmanin Skin Test-Positive Reactions of Ibizan Hound Dogs by Laura Ordeix, Sara Montserrat-Sangrà, Pamela Martínez-Orellana, Laia Solano-Gallego

“…The leishmanin skin test (LST) is an in vivo technique commonly used to evaluate the Leishmania-specific cellular immune response in dogs. However, information regarding the local immune response in LST-positive reactions is scarce. …”
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Bioceramic Surface Topography Regulating Immune Osteogenesis by Jianxin Hao, Lin Du, Yuening He, Chengtie Wu

“…Therefore, the exploration and regulation of immune response of the bioceramic interface will be beneficial to promote the bone regeneration effects. …”
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Immunological Evaluation for Personalized Interventions in Children with Tuberculosis: Should It Be Routinely Performed? by Laura E. Carreto-Binaghi, Esmeralda Juárez, Silvia Guzmán-Beltrán, María Teresa Herrera, Martha Torres, Alejandro Alejandre, José Arturo Martínez-Orozco, Eduardo Becerril-Vargas, Yolanda Gonzalez

“…Progression of Mycobacterium tuberculosis infection to active disease depends on mycobacterial virulence, environmental diversity, and host susceptibility and immune response. In children, malnutrition and immaturity of the immune system contribute to an inadequate immune response. …”
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Characterization of Transverse Aortic Constriction in Mice Based on the Specific Recruitment of Leukocytes to the Hypertrophic Myocardium and the Aorta Ascendens by Jan Lukas Kleiner, Odilia Köpke, Anton Faron, Yunyang Zhang, Jan Cornelssen, Mark Coburn, Stilla Frede, Lars Eichhorn, Christina Katharina Weisheit

“…It was determined whether TAC induces a characteristic leukocyte-driven immune response in the myocardium, aorta ascendens and descendens, spleen, blood, and draining lymph nodes supported by cytokine-driven chemotaxis in mice at 3, 6, and 21 days following surgery. …”
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Development of Cutaneous Leishmaniasis after Leishmania Skin Test by Paulo R. Machado, Augusto M. Carvalho, Gustavo U. Machado, Marina L. Dantas, Sérgio Arruda

“…The development of CL at the LST site suggests a strong Th1 immune response, and it is an in vivo documentation of the role of the host immune response in the pathology of CL. …”
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Changes in Serum Cytokine Levels in Active Tuberculosis With Treatment by Figen Deveci, H. Handan Akbulut, Teyfik Turgut, M. Hamdi Muz

“…Because the serum IL-12p40, IL-10, TNF-α, and IFN-γ levels were high in APTB, we believe that these cytokines have important roles in the immune response to Mycobacterium tuberculosis (M tuberculosis). …”
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YTHDF1-mediated m6A modification of GBP4 promotes M1 macrophage polarization in acute lung injury by Fengan Cao, Shilei Wang, Qiuyue Tan, Junna Hou, Yunlu Li, Wentao Ma, Shilong Zhao, Jing Gao

“…This research investigates the influence of m6A (N6-methyladenosine) modification on GBP4, a protein pivotal for macrophage polarization, a critical immune response in ALI. Methods Utilizing a mouse model to induce ALI, the study analyzed GBP4 expression in alveolar macrophages. …”
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EFFECTS OF MODERATELY VIRULENT AFRICAN SWINE FEVER VIRUS ON INTERLEUKIN-10 PRODUCTION by A. S. Pershin, I. V. Shevchenko, A. S. Igolkin, Ye. V. Aronova, N. N. Vlasova

“…A characteristic feature of African swine fever virus (ASFV) is the ability to escape from host immune response, affecting macrophages and replicating in them. …”
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Mesothelial cell responses to acute appendicitis or small bowel obstruction reactive ascites: Insights into immunoregulation of abdominal adhesion. by Melissa A Hausburg, Kaysie L Banton, Christopher D Cassidy, Robert M Madayag, Carlos H Palacio, Jason S Williams, Raphael Bar-Or, Rebecca J Ryznar, David Bar-Or

“…Overall, PAS patient rA showed a muted immune response compared to rA from naïve patients. Our data suggest that abdominal surgery may negatively impact future immune responses in the abdomen. …”
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Role of Mast Cells and Type 2 Innate Lymphoid (ILC2) Cells in Lung Transplantation by Esmaeil Mortaz, Saeede Amani, Sharon Mumby, Ian M. Adcock, Mehrnaz Movassaghi, Jelle Folkerts, Johan Garssen, Gert Folkerts

“…MCs modulate both the innate and the adaptive immune response in inflammatory disorders including transplantation. …”
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Role of Microbiota and Innate Immunity in Recurrent Clostridium difficile Infection by Stefano Bibbò, Loris Riccardo Lopetuso, Gianluca Ianiro, Teresa Di Rienzo, Antonio Gasbarrini, Giovanni Cammarota

“…In this narrative review, we discuss how the intestinal microbiota modifications and the modulation of innate immune response can lead to and exacerbate Clostridium difficile infection.…”
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Equivariant Hopf Bifurcation in a Time-Delayed Ring of Antigenic Variants by Israel Ncube

“…We consider an intrahost malaria model allowing for antigenic variation within a single species. The host’s immune response is compartmentalised into reactions to major and minor epitopes. …”
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