An Aloe-Based Composition Constituting Polysaccharides and Polyphenols Protected Mice against D-Galactose-Induced Immunosenescence by Mesfin Yimam, Teresa Horm, Alexandria O’Neal, Ping Jiao, Mei Hong, Qi Jia

“…UP360 was found to improve the immune response as evidenced by stimulation of innate and adaptive immune responses, increase antioxidant capacity as reflected by augmented SOD and Nrf2, and preserve vital immune organs, such as the thymus, from aging-associated damage. …”
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Trained Innate Immunity by Repeated Low-Dose Lipopolysaccharide Injections Displays Long-Term Neuroprotective Effects by Xiao-yan Zhou, Rong Gao, Jian Hu, Da-peng Gao, Yan-ling Liao, Jian-jun Yang

“…Disrupted immune response is an important feature of many neurodegenerative conditions, including sepsis-associated cognitive impairment. …”
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Role of Cytokines and Toll-Like Receptors in the Immunopathogenesis of Guillain-Barré Syndrome by Kishan Kumar Nyati, Kashi Nath Prasad

“…Herein, we discuss the crucial role of host factors such as cytokines and TLRs that activate the immune response and are involved in the pathogenesis of the disease.…”
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Nonprotein Structures from Mycobacteria: Emerging Actors for Tuberculosis Control by Luz M. Lopez-Marin

“…Immune response to Mycobacterium tuberculosis, the causal agent of tuberculosis, is critical for protection. …”
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Characterisation of the antibody-mediated selective pressure driving intra-host evolution of SARS-CoV-2 in prolonged infection. by Michael Schoefbaenker, Theresa Günther, Eva Ulla Lorentzen, Marie-Luise Romberg, Marc Tim Hennies, Rieke Neddermeyer, Marlin Maybrit Müller, Alexander Mellmann, Chiara Robin Bojarzyn, Georg Lenz, Matthias Stelljes, Eike Roman Hrincius, Richard Vollenberg, Stephan Ludwig, Phil-Robin Tepasse, Joachim Ewald Kühn

“…We studied the humoral immune response causing intra-host evolution in a B-cell depleted, haemato-oncologic patient experiencing clinically severe, prolonged SARS-CoV-2 infection with a virus of lineage B.1.177.81. …”
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Stability of Virus Infection Models with Antibodies and Chronically Infected Cells by Mustafa A. Obaid, A. M. Elaiw

“…Two virus infection models with antibody immune response and chronically infected cells are proposed and analyzed. …”
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Stimulation of Innate and Adaptive Immunity by Using Filamentous Bacteriophage fd Targeted to DEC-205 by Luciana D’Apice, Valerio Costa, Rossella Sartorius, Maria Trovato, Marianna Aprile, Piergiuseppe De Berardinis

“…RNA-Seq data analysis indicates that the bacteriophage fd virions are sensed as a pathogen by dendritic cells; they activate the danger receptors that trigger an innate immune response and thus confer a strong adjuvanticity that is needed to obtain a long-lasting adaptive immune response.…”
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Dendritic Cells and Leishmania Infection: Adding Layers of Complexity to a Complex Disease by Daniel Feijó, Rafael Tibúrcio, Mariana Ampuero, Cláudia Brodskyn, Natalia Tavares

“…Initially, DCs were described to play a protective role in activating the immune response against Leishmania parasites. However, several reports showed a dichotomic role of DCs in modulating the host immune response to susceptibility or resistance in CL. …”
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Resistance to P. brasiliensis Experimental Infection of Inbred Mice Is Associated with an Efficient Neutrophil Mobilization and Activation by Mediators of Inflammation by Felipe Fornias Sperandio, Gisele Pesquero Fernandes, Ana Carolina Silvério Cerqueira Mendes, Giulia Maria de Alencar Castro Bani, Vera Lucia Garcia Calich, Eva Burger

“…Patients may respond differently to PCM depending on the pattern of the acquired immune response developed. The onset of protective immune response is notably mediated by neutrophils (PMN) that play an important role through directly killing the fungi and also by interacting with other cell types to modulate the acquired protective immune response that may follow. …”
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Type I Interferon at the Interface of Antiviral Immunity and Immune Regulation: The Curious Case of HIV-1 by Adriano Boasso

“…Type I interferon (IFN-I) play a critical role in the innate immune response against viral infections. They actively participate in antiviral immunity by inducing molecular mechanisms of viral restriction and by limiting the spread of the infection, but they also orchestrate the initial phases of the adaptive immune response and influence the quality of T cell immunity. …”
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Innate and Adaptive Immunity in Calcific Aortic Valve Disease by Patrick Mathieu, Rihab Bouchareb, Marie-Chloé Boulanger

“…More recently, studies have emphasized that an adaptive immune response is triggered during CAVD. Herein, we are reviewing the link between the immune response and the development of CAVD and we have tried, whenever possible, to keep a translational approach.…”
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The effectiveness of forest onion Eleutherine bulbosa simplisia to prevent Streptococcus agalactiae infection on Nile tilapia Oreochromis sp. by Amalia Istiqomah, Widanarni Widanarni, Munti Yuhana

“… Forest onion potentially acts as an immunostimulant, enhancing the immune response of tilapia to pathogen infection. This study aimed to evaluate the effectiveness of forest onion simplisia on growth performance, immune response, and resistance of tilapia to Streptococcus agalactiae infection. …”
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On the global dynamics of a model for tumor immunotherapy by Denise E. Kirschner, Alexei Tsygvintsev

“…A mathematical model wasdeveloped that explored the immune response to tumors that was used to study a special type of treatment[3]. …”
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Multifunctional Roles of Reticular Fibroblastic Cells: More Than Meets the Eye? by H. G. Alvarenga, L. Marti

“…Despite its structural function in the lymph nodes being well established, recent studies indicate that the FRCs also play a key role in immunological processes, associated with cell transit, immune response, and cells activation quality, and contribute to peripheral tolerance. …”
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Vaccines for cancer interception in familial adenomatous polyposis by David E. Johnson, Mary L. Disis

“…Immunologic memory will allow the immune response to persist and the specificity of the immune response will limit toxicity to the targeted polyp. …”
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Lipoxin A4 levels correlate with severity in a Spanish COVID-19 cohort: potential use of endogenous pro-resolving mediators as biomarkers by Sergio Sánchez-García, Rafael I. Jaén, Roberto Lozano-Rodríguez, José Avendaño-Ortiz, Alejandro Pascual‐Iglesias, Laura Hurtado-Navarro, Eduardo López-Collazo, Eduardo López-Collazo, Lisardo Boscá, Lisardo Boscá, Patricia Prieto, Patricia Prieto, Patricia Prieto

“…Thus, the possible outbreak of new biological diseases in the future makes it necessary to deepen the knowledge of this uncontrolled immune response and look for reliable biomarkers to help us predict its potential health impact. …”
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Inflammasome in Intestinal Inflammation and Cancer by Tiago Nunes, Heitor S. de Souza

“…Here, we show that the available data points towards the importance of the inflammasome in the innate intestinal immune response, being the complex involved in the maintenance of intestinal homeostasis, correct intestinal barrier function and efficient elimination of invading pathogens.…”
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Based on the immune system: the role of the IL-2 family in pancreatic disease by Yuqing Zhu, Zheng Lu, Zhuo Wang, Jiao Liu, Ke Ning

“…The IL-2 family, consisting of IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21, is a key regulator of the immune response. As an important endocrine and digestive organ, the function of the pancreas is regulated by the immune system. …”
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Hepatitis C Virus Adaptation to T-Cell Immune Pressure by A. Plauzolles, M. Lucas, S. Gaudieri

“…This paper will review the data on viral diversity observed between and within hosts infected with HCV from the acute to the chronic stage of infection and will focus on viral adaptation to the host’s T-cell immune response.…”
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Impact of Combined Antiretroviral Treatment (cART) on Latent Cytomegalovirus Infection by Aura Temereanca, Luminita Ene, Gratiela Tardei, Camelia Grancea, Cristian L. Achim, Simona Ruta

“…A good immune response to treatment was significantly associated with CMV-specific cellular immunity: IFN-γ level was positively correlated with CD4 and CD8-T cell counts. …”
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