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Protocol for a multicentre randomised controlled trial examining the effects of temporarily pausing Bruton tyrosine kinase inhibitor therapy to coincide with SARS-CoV-2 vaccination and its impact on immune responses in patients with chronic lymphocytic leukaemia
Published 2023-09-01“…This study aims to determine in patients with chronic lymphocytic leukaemia (CLL) if a 3-week pause in Bruton tyrosine kinase inhibitor therapy (BTKi) starting 1 week before delivery of SARS-CoV-2 vaccine booster, improves vaccine immune response when compared with continuation of BTKi.Methods and analysis An open-label, randomised controlled superiority trial will be conducted in haematology clinics in approximately 10 UK National Health Service (NHS) hospitals. …”
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362
Analysis of Mannose‐Binding Lectin Protein and mRNA Levels on Selected Chicken Breeds in South Africa
Published 2024-11-01Subjects: Get full text
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363
Exploring the role of ESR1 mutations in metastatic hormone receptor-positive breast cancer T cell immune surveillance disruption
Published 2025-02-01Subjects: Get full text
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364
A Multiagent Alphavirus DNA Vaccine Delivered by Intramuscular Electroporation Elicits Robust and Durable Virus-Specific Immune Responses in Mice and Rabbits and Completely Protects Mice against Lethal Venezuelan, Western, and Eastern Equine Encephalitis Virus Aerosol Challenges
Published 2018-01-01Get full text
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365
Modeling the co-infection of HTLV-2 and HIV-1 in vivo
Published 2024-11-01Subjects: Get full text
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366
Systems Biological Approaches Reveal Non-additive Responses and Multiple Crosstalk Mechanisms between TLR and GPCR Signaling
Published 2012-09-01Subjects: Get full text
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367
Interferon-γ production in response to the cytotoxic T lymphocyte epitope within an antigen incorporated in simian virus 40 virus-like particles
Published 2025-01-01Subjects: Get full text
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368
Resiquimod induces a mixed Th1 and Th2 response via STAT1 and STAT3 signalling in chickens
Published 2025-03-01Subjects: Get full text
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369
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Corrigendum to “Does the use of two probiotic bacteria (Latiplantibacillus plantarum and Bacillus toyonensis) as water additives enhance growth performance, the immune responses, antioxidative maintenance, water quality and intestinal bacterial counts of Nile tilapia?”...
Published 2025-03-01Get full text
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371
Single-cell RNA sequencing and AlphaFold 3 insights into cytokine signaling and its role in uveal melanoma
Published 2025-01-01Subjects: Get full text
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372
Effect of integrin α5 on NLRP3 expression in periodontal ligament fibroblasts within an inflammatory microenvironment
Published 2025-01-01Subjects: “…periodontitis|integrin α5|integrin α5 inhibitor|periodontal ligament fibroblasts|paracrine|immune response|inflammatory microenvironment|nod-like receptor thermal protein domain associated protein 3|conditioned medium…”
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373
Oral Tolerance: A New Tool for the Treatment of Gastrointestinal Inflammatory Disorders and Liver-Directed Gene Therapy
Published 1999-01-01“…Thus, oral tolerance induces suppressor lymphocytes that mediate immune response downregulation by induction of a shift from a proinflammatory T helper cell type 1 to an anti-inflammatory T helper cell type 2 immune response.…”
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374
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Effects of female sexual chemosignals on mucosal immunity in BALB/c and C57BL/6 male mice
Published 2016-12-01“…The immune response to immunogenic stimuli depends on various factors like cytokine context, way of entry, and immune status of the organism. …”
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376
Gender-Specific Cytokine Pathways, Targets, and Biomarkers for the Switch from Health to Adenoma and Colorectal Cancer
Published 2011-01-01“…Our results show that the interferon (IFN)γ production pathway for immune response homeostasis is specific to men whilst the interleukin- (IL-) 6 production pathway for immune response homeostasis is specific to women. …”
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377
Roitt's essential immunology /
Published 2017Table of Contents: “…Innate immunity -- Specific acquired immunity -- Antibodies -- Membrane receptors for antigen -- Antigen-specific recognition -- Immunological methods and applications [JS2] -- The anatomy of the immune response -- Lymphocyte activation -- The production of effectors -- The regulation of the immune response -- Development and evolution of the immune response -- Adversarial strategies during infection -- Vaccines -- Immunodeficiency -- Allergy and other hypersensitivities -- Transplantation -- Tumor immunology -- Autoimmune diseases.…”
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378
A Metapopulation Model Of Granuloma Formation In The Lung During Infection With Mycobacterium Tuberculosis
Published 2005-07-01“…The immune response to Mycobacterium tuberculosis infection (Mtb) is the formation of unique lesions, called granulomas. …”
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379
From the curricular to the investigative, a look at COVID-19
Published 2021-10-01“…The objective of this work is to assess the significance of the subject for the interpretation of the deviations of the immune response and to make suggestions to enhance the research work in it.…”
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380
Immunogenicity of RSV F DNA Vaccine in BALB/c Mice
Published 2016-01-01“…Our data evidently showed that the RSV F DNA vaccine activated the Th1 biased immune response and led to the production of neutralizing antibodies, which is the desired immune response required for protection from RSV infections.…”
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