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1501
A novel imatinib analogue inhibitor of chronic myeloid leukaemia: design, synthesis and characterization—explanation of its folded conformation
Published 2025-01-01“…Additionally, supramolecular interactions in the crystal are mediated by hydrogen bonds and dispersion forces, forming dimers and layered structures. …”
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1502
Synthesis, H2S releasing properties, antiviral and antioxidant activities and acute cardiac effects of nucleoside 5′-dithioacetates
Published 2025-01-01“…Abstract Hydrogen sulfide (H2S) is an endogenous gasotransmitter with cardioprotective and antiviral effects. …”
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1503
Discovery of the Richest Pulsating Ultramassive White Dwarf
Published 2025-01-01“…In this work, we report the discovery of 19 pulsation modes in the UM WD star WD J0135+5722, making it the richest pulsating hydrogen-atmosphere UM WD known to date. This object exhibits multiperiodic luminosity variations with periods ranging from 137 to 1345 s, typical of pulsating WDs in the ZZ Ceti instability strip, which is centered at T _eff ∼ 12,000 K. …”
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1504
Effects of Calcium-Oxide-Modified Biochar on the Anaerobic Digestion of Vacuum Blackwater
Published 2025-01-01“…The syngas produced is a versatile energy carrier that can be utilized as a source of hydrogen, electricity, and heat, making it a valuable resource for various applications, including fuel cells and power generation. …”
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1505
Evaluation of fluorinated phospholipid analogs: A study on ADMET profiles, molecular docking and dynamics simulation in anticancer therapy
Published 2025-01-01“…Molecular docking discernible vigorous interactions with Edelfosine drug displaying greater binding stability and consistent hydrogen bonding as confirmed by 100 ns molecular dynamics simulations. …”
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1506
Characterization of the Liquid Fuel Produced from Catalytic Depolymerization of Polymeric Waste Using Batch Reactor
Published 2024-12-01“…The CHONS analyzer indicated the percentage of carbon, hydrogen, oxygen, nitrogen, and sulfur content range 81.64-85.51%, 12-31-18.04%, 0.00-1.51%, 0.00-0.73%, and 0.10- 0.97% respectively. …”
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1507
Combined Graphene Oxide with 2-Methoxyestradiol for Effective Anticancer Therapy in-vitro Model
Published 2025-01-01“…The presence of polar hydroxyl groups enables the binding of 2-ME to GO/rGO through hydrogen bonds with epoxy and hydroxyl groups located on the surface and carbonyl and carboxyl groups located at the edges of graphene flake sheets.Methods: The patented method of producing the subject of the invention and the research results regarding its anticancer effectiveness via cytotoxicity in an in vivo model (against A375 melanoma and 143B osteosarcoma cells) are described.Results: It was shown that the inhibition of PTP1B phosphotyrosine phosphatase is one of the mechanisms of action of GO functionalised with 2-ME (GO-2-ME). …”
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1508
Typical and atypical metabolic characteristics of three iridaceae isoflavone components: in vitro and in silico studies
Published 2025-02-01“…Furthermore, molecular simulations showed that tectorigenin and irigenin bind to the orthosteric site of CYP isoforms via hydrogen bonds and π-π stacking, whereas irisflorentin is principally bound to CYP1A2 via π-π stacking and hydrophobic interactions.ConclusionCollectively, these Iridaceae isoflavone aglycones can be metabolized by CYP enzymes with typical or atypical kinetic characteristics. …”
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1509
Immunoregulative coating for scarless healing in anterior cruciate ligament reconstruction
Published 2025-03-01“…Comprising gelatin methacrylate (GelMA), polyethyleneglycol diacrylate (PEGDA), and sulfated polysaccharide (SCS), the hydrogel forms a hydrogen-bonded lubricating layer to reduce friction. …”
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1510
New View on the Genesis of the Bashuihe Pluton, Laoshan Granites, China: Indications from Fluid Inclusions and H–O Isotopes
Published 2021-01-01“…The emplacement depth ranged from 2.73 km to 4.43 km, indicating medium-shallow granite. A hydrogen and oxygen isotope analysis (δD=−83.58–−67.17, δ18OH2O=0.83–0.39) revealed that the diagenetic fluids of the Bashuihe pluton represented a mixed hydrothermal solution composed of meteoric water and magmatic water. …”
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1511
Integrated system for electrolyte recovery, product separation, and CO2 capture in CO2 reduction
Published 2025-01-01“…Cations like K+ in the ISM flow through the cathodic CEM into the catholyte to balance the OH− ions from hydrogen evolution. ERSS recycles electrolyte-adsorbed CO2, recovers KOH with a 94.0% K+ yield, and achieves an 86.2% separation efficiency for CO2R products. …”
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1512
Pectin‐decorated selenium nanoparticles as a nanocarrier of curcumin to achieve enhanced physicochemical and biological properties
Published 2019-10-01“…Cur was successfully encapsulated into pectin‐SeNPs through hydrogen bonding interactions with an encapsulation efficiency of ∼60.6%, a loading content of ∼7.4%, and a pH‐dependent and controlled drug release in vitro. …”
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1513
A Structural Model of Truncated Gaussia princeps Luciferase Elucidating the Crucial Catalytic Function of No.76 Arginine towards Coelenterazine Oxidation.
Published 2025-01-01“…Moreover, R76, a validated activity-critical amino acid residue, resides in the cavity and forms a stable hydrogen bond with CTZ. Then, we constructed a cluster model to examine the CTZ oxidation pathway in the cavity using Density Functional Theory (DFT) calculations. …”
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1514
Biological control of bacterial wilt in pathumma; Curcuma alismatifolia
Published 2023-11-01“…The optimal conditions for all antagonistic bacterial isolates were 25 or 30 degrees Celcius, at potential of hydrogen 7-8 in modified tryptic soy medium containing 0.5 percent (weight /volume) glucose or sucrose and 1.5 or 2 percent (weight/volume) peptone. …”
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1515
Promoting in-situ stability of hydroxide exchange membranes by thermally conductive network for durable water electrolysis
Published 2025-01-01“…Abstract Hydroxide exchange membrane (HEM) water electrolysis is promising for green hydrogen production due to its low cost and excellent performance. …”
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1516
Effect of the host-specific toxin SnTOX3 from Stagonospora nodorum on ethylene signaling pathway regulation and redox-state in common wheat
Published 2019-11-01“…The results of plant redox status estimation showed that ethylene inhibited accumulation of hydrogen peroxide in SnTox3-sensitive genotypes by regulating the operation of various pro-/antioxidant enzymes at the transcriptional and posttranslational levels. …”
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1517
Anisotropic robust Poly(vinyl alcohol) hydrogels inspired by bio-tissue
Published 2025-02-01“…The excellent mechanical properties of developed PVA hydrogels are attributed to two aspects: 1) the constructed anisotropic aligned pore wall structures played a key role in distributing the stress and thus impede local crack initiation and propagation, and 2) the formation of abundant sacrificial hydrogen bonds which effectively dissipate energy through dynamic breaking and reformation. …”
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1518
A Microfluidic Biosensor for Quantitative Detection of <i>Salmonella</i> in Traditional Chinese Medicine
Published 2024-12-01“…Subsequently, the mixture flowed into the reaction cell, where the MNBs-<i>Salmonella</i>-Au@PtNCs complex was captured by the magnetic field. After washing, hydrogen peroxide-tetramethylbenzidine substrate (H<sub>2</sub>O<sub>2</sub>-TMB) was added, reacting with the Au@PtNCs peroxidase to produce a blue reaction product. …”
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1519
Tumor Microenvironment‐Responsive Nanoparticles Enhance IDO1 Blockade Immunotherapy by Remodeling Metabolic Immunosuppression
Published 2025-02-01“…The released Mn2+ catalyzed the production of abundant reactive oxygen species and nitric oxide from hydrogen peroxide and GSNO, and the generated nitric oxide, synergistically with 1‐MT, inhibited the accumulation of kynurenine mediated by IDO1 in the tumor. …”
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1520
Oral-malodor measurement and intention to quit smoking in men: A before–after study
Published 2023-07-01“…Other variables, such as lung age deficit, exhaled CO concentration, and hydrogen sulfide concentration (another component of oral malodor), were not significantly associated. …”
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