A study on awareness regarding cigarettes and other tobacco products act (COTPA Act) among hospital staff of medical college, Kanpur: A mixed method study by Aradhana Yadav, Sonam, Samarjeet Kaur, Santosh K. Barman, Seema Barman

“…The aim of the study is to evaluate hospital staff’s knowledge of the COTPA Act and their enablers and hurdles using qualitative analysis. Settings and Design: This study was conducted in GSVM Medical College, and this was a convergent parallel mixed-methods study, with a quantitative component (cross-sectional survey) complemented by a qualitative component (descriptive study). …”
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Adoption of full-culm bamboo as a mainstream structural material by Kent A. Harries

“…This paper provides one perspective to overcoming these hurdles through a proposed approach of materials informatics used to inform context-appropriate building material and design standards.…”
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Public Accountability and its Diverse Context: a Tale from Different Disciplinary Parameters. by Basheka, Benon

“…One of the greatest hurdles of sound administrative and governance contexts in Africa remains that of accountability. …”
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Improving CD3 bispecific antibody therapy in solid tumors using combination strategies by Katy Lloyd, Jim Middelburg, Vitalijs Ovcinnikovs, Nora Pencheva, Kristel Kemper, Thorbald van Hall

“…Despite these recent advances, the success of CD3 bsAbs in solid cancer has been hampered by hurdles like limited intratumoral T cell numbers, immunosuppressive tumor microenvironments (TME), and poor memory T-cell induction. …”
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Embracing Generative Artificial Intelligence in Clinical Research and Beyond by Henry P. Foote, MD, Chuan Hong, PhD, Mohd Anwar, PhD, Maria Borentain, MD, Kevin Bugin, PhD, Nancy Dreyer, PhD, MPH, Josh Fessel, MD, PhD, Nitender Goyal, MD, Morgan Hanger, MPP, Adrian F. Hernandez, MD, Christoph P. Hornik, MD, PhD, MPH, Jennifer G. Jackman, PhD, MBA, Alistair C. Lindsay, MD, MPH, DPhil, Michael E. Matheny, MD, Kerem Ozer, MD, Jan Seidel, PhD, Norman Stockbridge, MD, PhD, Peter J. Embi, MD, Christopher J. Lindsell, PhD

“…Challenges include technical hurdles, ethical dilemmas, and regulatory uncertainties. …”
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A spatial inventory of freshwater macroinvertebrate occurrences in the Guineo-Congolian biodiversity hotspot by Emmanuel O. Akindele, Abiodun M. Adedapo, Oluwaseun T. Akinpelu, Esther D. Kowobari, Oluwatosin C. Folorunso, Ibrahim R. Fagbohun, Tolulope A. Oladeji, Olanrewaju O. Aliu, Oluwatobiloba S. Adenola, Babasola W. Adu, Francis O. Arimoro, Sylvester S. Ogbogu, Sami Domisch

“…Aside from the underreporting and underestimation of freshwater ecosystems, the challenges regarding incorrect coordinates and taxonomical inaccuracies in freshwater species occurrence data pose another major hurdle that may hinder freshwater conservation efforts in the hotspot. …”
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A review on probiotics and dietary bioactives: Insights on metabolic well-being, gut microbiota, and inflammatory responses by Alice Njolke Mafe, Great Iruoghene Edo, Osamah S. Majeed, Tayser Sumer Gaaz, Patrick Othuke Akpoghelie, Endurance Fegor Isoje, Ufuoma Augustina Igbuku, Joseph Oghenewogaga Owheruo, Rapheal Ajiri Opiti, Yasal Garba, Arthur Efeoghene Athan Essaghah, Dina S. Ahmed, Huzaifa Umar

“…By examining the connections between probiotics, gut microbiota, and outcomes such as digestive health, immune function, and metabolic well-being, this review identifies conditions where probiotics show potential benefits. It also addresses hurdles, including variability in strain effectiveness and dosage, and outlines future research areas, particularly personalized probiotic approaches. …”
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Exploring Novel Non-Operative Treatments for Osteoarthritis: An Examination of Innovative Therapies by Piotr Robert Bakuła, Kamila Jałocha, Joanna Zygadło

“…Despite significant progress, challenges such as translational hurdles, cost barriers, and long-term efficacy require further investigation. …”
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GENDER EQUALITY AND ECONOMIC DEVELOPMENT IN NIGERIA: THE ROLE OF CIVIL SOCIETY by KAZEEM ADEREMI ASIYANBI, AHMED YUSUF BABATUNDE, ADENIYI MICHAEL ADEWUSI

“…It examines the techniques used by CSOs, assesses their impact on policy reforms and public attitudes, and analyzes the hurdles to accomplishing their goals. This study emphasized the literature rather than the major concerned respondents that have been the focus of previous researchers.  …”
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Sustainable 3D printing of bone scaffolds using animal biowaste feedstocks by A. Dukle, M. Ravi Sankar

“…The study also addresses the challenges and future perspectives of biowaste-derived feedstocks for bone tissue engineering, including regulatory hurdles, biocompatibility, and scalability.…”
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ETHNIC POLITICS AND SUSTAINABLE DEMOCRACY IN NIGERIA by UKWU FELIX EMEKA

“…The research contends that the endemic nature of ethnic politics presents significant hurdles to democracy's survival in Nigeria. The findings reveal various symptoms and ramifications of ethnic politics that hinder the consolidation of democracy, including heightened calls for self-determination, escalating insecurity, and stalled development. …”
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QeMFi: A Multifidelity Dataset of Quantum Chemical Properties of Diverse Molecules by Vivin Vinod, Peter Zaspel

“…Much research is progressing in this direction for diverse applications ranging from energy band gaps to excitation energies. One hurdle for effective research here is the lack of a diverse multifidelity dataset for benchmarking. …”
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The effect of smart contracts (blockchain technology) on Jordan’s land registry and survey department for sustainable development by AbdelKarim Fawwaz AlBataineh

“…Despite these promising results, the study acknowledges critical challenges such as the need for technical expertise, regulatory frameworks, and initial investment hurdles. Addressing these challenges is crucial for balanced implementation and sustained engagement with the technology. …”
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A Critical and Progressive Review on Maternal and Child Health Policies in India by Prity Kumari, Anand Kumar Chaudhary

“…The current mother and child health situation in India is a complex topic with both hurdles and improvement. The Government of India has the foresight to reduce maternal mortality with the help of different programmes and healthcare facilities being introduced and cautiously implemented. …”
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Treatment completion of drug-resistant tuberculosis in Ethiopia: A perspective from healthcare users. by Ahmed Reshid Tusho, Sheila Theresa Mokoboto-Zwane

“…The seven prominent themes revealed were: drug-related challenges encompassing adverse events and the lengthy treatment duration; clinical hurdles such as delayed consultation following prolonged illness, diagnostic delays, and suboptimal dosages; psycho-emotional difficulties including emotional trauma and facing stigma from both the community and healthcare professionals; socio-economic constraints; service-related issues such as interruptions in monitoring tests, inadequate follow-up, and accessibility barriers; patient-related factors such as a false sense of recovery and reverting to previously quit habits; and provider-related issues such as lack of responsiveness and ineffective communication. …”
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Thyroid disorders among patients with type II Diabetes Mellitus by Mariwan Abdulla Hama Salih

“…These diseases currently the major hurdle among patient and become the great challenge in front of government capability to fight the problem. …”
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Hepatobiliary organoid research: the progress and applications by Rui-Qi Zou, Rui-Qi Zou, Yu-Shi Dai, Yu-Shi Dai, Fei Liu, Fei Liu, Si-Qi Yang, Si-Qi Yang, Hai-Jie Hu, Hai-Jie Hu, Fu-Yu Li, Fu-Yu Li

“…However, the technology is not yet mature, and many hurdles still exist that need to be overcome. The combination with new technologies such as CRISPR-HOT, organ-on-a-chip may inject new vitality into future development.…”
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Embracing E-Court Innovation: Advancing Maslahah Mursalah in Indonesia's Religious Courts by Eti Yusnita, Yuswalina, Muhammad Toriq

“…The findings highlight that while the e-court system largely aligns with existing regulations, hurdles like inadequate network infrastructure and limited public digital literacy persist. …”
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Robust adaptive optimization for sustainable water demand prediction in water distribution systems by Ke Wang, Jiayang Meng, Zhangquan Wang, Kehua Zhao, Banteng Liu

“…Despite the potential benefits, the inherent non-stationarity of water consumption data poses significant hurdles to the predictive accuracy of forecasting models. …”
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Immunological Approaches and Different Strategies for Vaccine Development Against SARS-COV-2 by Muhammed Babakir-Mina

“…This study gives an update on the current immunological approaches and vaccination strategies for the emerging SARS-COV-2, and discusses the challenges and hurdles to overcome for developing efficacious vaccines against this dangerous pathogen. …”
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