How Can Law and Policy Reform Shape Human Resource Strategies in Indonesian State Universities Post-Law No. 20 of 2023? by Siti Mursidah, Cahya Wulandari, Moh Khoiruddin, Muhammad Sayuti Hassan, Ricky Dermawan Fauzi

“…Adjusting organizational structures and enhancing staff competencies remain major hurdles. The novelty of this research lies in its focus on the intersection of legal reform and HR strategies in higher education. …”
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Epsin3 promotes non-small cell lung cancer progression via modulating EGFR stability by Huiling Su, Jie Shen, Chenzi Gao, Yue Zhao, Wanyu Deng, Bo Qin, Xin Zhang, Juan Lai, Qian Wang, Jie Dou, Min Guo

“…In this study, we aimed to investigate the role of EPN3 in modulating EGFR function, its effects on NSCLC progression, and its potential involvement in tyrosine kinase inhibitor (TKI) resistance, which remains a significant hurdle in NSCLC treatment. Results Our findings revealed that the expression of EPN3 is significantly up-regulated in NSCLC patients. …”
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Digital twins as global learning health and disease models for preventive and personalized medicine by Xinxiu Li, Joseph Loscalzo, A. K. M. Firoj Mahmud, Dina Mansour Aly, Andrey Rzhetsky, Marinka Zitnik, Mikael Benson

“…However, widespread implementation faces several challenges: (1) characterizing dynamic molecular changes across multiple biological scales; (2) developing computational methods to integrate data into DTs; (3) prioritizing disease mechanisms and therapeutic targets; (4) creating interoperable DT systems that can learn from each other; (5) designing user-friendly interfaces for patients and clinicians; (6) scaling DT technology globally for equitable healthcare access; (7) addressing ethical, regulatory, and financial considerations. Overcoming these hurdles could pave the way for more predictive, preventive, and personalized medicine, potentially transforming healthcare delivery and improving patient outcomes.…”
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RBD-displaying OMV nanovaccine boosts immunity against SARS-CoV-2 by Rang Feng, Ruo-Yi Xue, Chang Liu, Guo-Cheng Li, Yan Deng, Zhe Jin, Jing-Yi Liu, Shan-Shan Zhang, Hao Cheng, Man-Ying Guo, Quan-Ming Zou, Hai-Bo Li

“…However, its low immunogenicity has been a hurdle, resulting in the production of minimal anti-RBD antibodies even when combined with alum adjuvant. …”
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Assessing The Impact of Record Managers Training on Organizational Performance: A Case Study of Kabale University. by Kyasimiire, Sheillah

“…From objective two above, it was found out that there was a lack of basic skills and competencies for handling records, technological hurdles because most of the information is kept in the form of multimedia, insufficient cost the record center cannot provide a good service and without good planning on the budget the record, records management are not specific to a particular file format. …”
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TEACHERS’ PROFILE, MOTIVATION, APTITUDE, AND SATISFACTION IN A VIRTUAL UPSKILLING ENVIRONMENT by Dave E. Marcial, Jan Cynth Palama, Fredlie Bucog, Steven Binarao

“…This shift presented new hurdles for teachers who needed to acquire the knowledge and skills essential for effective online teaching. …”
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Protecting the American dream for socially vulnerable families: An evaluation of state-level policies to improve housing security and protect mobile home communities by Morgan Clennin, Denise Hartsock, Olivia Goodman, Stacie Daugherty, Cheryl Kelly

“…The purpose of this study was to evaluate the implementation process and impact of newly enacted mobile home park policies on the housing security of Colorado residents and to identify policy implementation hurdles and successes. Study Design: Policy implementation evaluation using mixed methods. …”
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Differentially expressed microRNAs in pre-transplant lung biopsies target immune checkpoint proteins and can predict primary graft dysfunction in lung transplantation by Vitale Miceli, Pia Ferrigno, Claudio Centi, Claudia Carcione, Gioacchin Iannolo, Valentina Agnese, Giovanna Lo Iacono, Rosa Liotta, Pier Giulio Conaldi, Massimo Pinzani, Lavinia De Monte, Alessandro Bertani

“…However, primary graft dysfunction (PGD) remains one of the most relevant hurdles. Although PGD is attributed to ischemia-reperfusion injury (IRI), immune responses, primarily T cell-mediated, may play a pivotal role in its pathogenesis. …”
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Effects of Nontraditional Division III Lacrosse Participation on Movement Pattern Quality and Dynamic Postural Control by Christopher Rosenborough, Sean M. Collins, Edward Smith, Thomas G Bowman

“…Asymmetry frequency significantly increased in males in the hurdle step from two individuals to nine ($\chi^2$~1~=25.52, p<0.01), inline lunge from 10 to 20 ($\chi^2$~1~=12.50, p<0.01), and shoulder mobility from 4 to 21 ($\chi^2$~1~=78.53, p<0.01). …”
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