EPA’s Endocrine Disruptor Screening Program (EDSP) by Frederick M. Fishel

“…The relationship between human diseases of the endocrine system and exposure to environmental contaminants is poorly understood and controversial. …”
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EPA’s Endocrine Disruptor Screening Program (EDSP) by Frederick M. Fishel

“…The relationship between human diseases of the endocrine system and exposure to environmental contaminants is poorly understood and controversial. …”
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Evolutionary conserved regulation of TFEB stability by the E3 ubiquitin ligase WWP2 modulates response to stress in vivo by Juan A. Garcia-Sanchez, Estelle Bonnet, Céline Loubatier, Anne Doye, Guillaume Paillier, Fabien Segui, Frédéric Larbret, Paul Chaintreuil, Ludovic Batistic, Cédric Torre, Marcel Deckert, Jolanta Polanowska, Patrick Munro, Laurent Boyer, Orane Visvikis

“…Dysregulation of TFEB is associated with a range of human diseases, and understanding the regulatory mechanisms of TFEB is crucial for identifying potential drug targets. …”
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Forward programming of hPSCs to neutrophils using chemically defined media by Hayley E. Hall, Xiaoping Bao, Cheng Dong, Xiaojun Lance Lian

“…In recent years, PMNs have gained increasing recognition for their significant involvement in the pathogenesis of a wide array of human diseases, including sepsis, pulmonary conditions, autoimmune disorders, and various cancers. …”
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Dual graph-embedded fusion network for predicting potential microbe-disease associations with sequence learning by Junlong Wu, Liqi Xiao, Liu Fan, Lei Wang, Xianyou Zhu, Xianyou Zhu

“…Dysbiosis, or an imbalance in these microbial communities, is strongly linked to a variety of human diseases. Therefore, understanding the impact of microbes on disease is essential. …”
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Using Protein Painting Mass Spectrometry to Define Ligand Receptor Interaction Sites for Acetylcholine Binding Protein by Alexandru Graur, Natalie Erickson, Nadine Kabbani

“…The pharmacological targeting of nAChRs, using small molecules or peptides, is a promising approach for the development of compounds for the treatment of various human diseases including inflammatory and neurogenerative disorders such as Alzheimer’s disease. …”
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HCNetlas: A reference database of human cell type-specific gene networks to aid disease genetic analyses. by Jiwon Yu, Junha Cha, Geon Koh, Insuk Lee

“…These findings suggest that HCNetlas has the potential to link disease-associated genes to cell types of action, facilitating development of cell type-resolved diagnostics and therapeutic strategies for complex human diseases.…”
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RECQL4 requires PARP1 for recruitment to DNA damage, and PARG dePARylation facilitates its associated role in end joining by Mansoor Hussain, Prabhat Khadka, Komal Pekhale, Tomasz Kulikowicz, Samuel Gray, Alfred May, Deborah L. Croteau, Vilhelm A. Bohr

“…Mutations in RECQL4 have been associated with various human diseases, including Rothmund–Thomson syndrome. RECQL4 is involved in regulating major DNA repair pathways, such as homologous recombination and nonhomologous end joining (NHEJ). …”
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Anal Sphincter Function After Hemorrhoidectomy by A. M. Kuzminov, O. Yu. Fomenko, I. A. Mukhin, S. A. Frolov, D. V. Vyshegorodtsev, V. Yu. Korolik, S. T. Minbaev, S. V. Belousova

“…The haemorrhoid disease is one of the most common human diseases and the most common reason for visiting a coloproctologist. …”
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Determination of the levels of some selected metals in ocimum lamiifolium in Wolaita Zone, Southern Ethiopia by Eyob Yishak, Teferi Tademe Dadebo

“… Medicinal plants have worldwide applications in the treatment of different types of human diseases. Among the medicinal plants of Ethiopia, Ocimum lamiifolium Hochst. …”
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Sodium dichloroisocyanurate: a promising candidate for the disinfection of resilient drain biofilm by Abbie Martin, Natasha Doyle, Tom F. O'Mahony

“…Biofilms can cause a range of human diseases and are responsible for 1.7 million hospital-acquired infections in the US annually, providing an economic burden of $11.5 billion in treatment costs. …”
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Post-translational modifications as a key mechanism for herpes simplex virus type I evasion of host innate immunity by Yongxing Zhang, Junlei Xie, Ying Feng, Abdul Qadeer, Shanni Li, Xu Deng, Lipeng Zhu, Bo Kong, Zanxian Xia, Zanxian Xia

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Significance of immune factors in Crohn's disease development by D. S. Stavtsev, T. A. Astrelina, O. V. Knyazev, T. V. Pukhlikova

“…Series of the population studies, confirming association of HLA antigens with human diseases were carried out. Main histocompatibility complex (MHC) plays the leading role in immune response as well as in development of CD, therefore occurrence of disease is related to changes at genetic level. …”
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Cell-free DNA: a metabolic byproduct with diagnostic and prognostic potential in rheumatic disorders by Fancheng Liu, Fancheng Liu, Yazhen Su, Yazhen Su, Xinling Liu, Li Zhao, Li Zhao, Zewen Wu, Zewen Wu, Yang Liu, Yang Liu, Liyun Zhang, Liyun Zhang

“…Further research has shown that cfDNA is associated with a wide range of human diseases and may have a feedback relationship with inflammation, potentially serving as a non-invasive, accurate, sensitive, and rapid biomarker for clinical applications in disease differential diagnosis, activity monitoring, and prognosis assessment. …”
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Protein arginine methyltransferase 7 linked to schizophrenia through regulation of neural progenitor cell proliferation and differentiation by Ting Shen, Jing Yu, Bin Xie, Cuiping Huang, Jingjie Cui, Kefu Liu, Chunyu Liu, Chao Chen

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