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2001
Engineering tomato disease resistance by manipulating susceptibility genes
Published 2025-02-01“…Furthermore, we address the challenges associated with growth-defense trade-offs and propose strategies, such as hormonal pathway modulation and precise regulatory edits, to overcome these limitations. …”
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2002
Amphibian newts as experimental models for studying weight gain after castration
Published 2024-02-01“…In mammals, decreases in sex hormones caused by testicular castration can affect body shape and occasionally lead to pathologies such as obesity. …”
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2003
Maternal Plasma Metabolomic Profiles in Spontaneous Preterm Birth: Preliminary Results
Published 2018-01-01“…We determined 51 metabolites using publicly available databases that could be subdivided into one of the five groups: amino acids, fatty acids, lipids, hormones, and bile acids. PLS-DA models, verified by SVM classification accuracy, differentiated preterm birth and term delivery groups. …”
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2004
Feeding Expressed Breast Milk Alters the Microbial Network of Breast Milk and Increases Breast Milk Microbiome Diversity over Time
Published 2024-12-01“…Breastfeeding supplies nutrition, immunity, and hormonal cues to infants. Feeding expressed breast milk may result in de-phased milk production and feeding times, which distort the real-time circadian cues carried by breast milk. …”
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2005
Polystyrene microplastics disrupt adrenal steroid synthesis in male mice via mitochondrial dysfunction
Published 2025-01-01“…We proposed that mitochondrial dysfunction not only directly influenced the biosynthetic processes of steroid hormones but also induced cell apoptosis through the initiation of cellular oxidative stress. …”
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2006
Experimenter Effects on Pain Reporting in Women Vary across the Menstrual Cycle
Published 2015-01-01“…Based on the menstrual calendars 94 naturally cycling women and 38 women using hormonal contraceptives (Mage=19.83, SD=3.09) were assigned to low and high fertility groups. …”
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2007
The potential of local orange peel-derived eco-enzymes in producing indole acetic acid
Published 2023-12-01“…Objective: This study aims to evaluate the capacity of ecoenzymes derived from local citrus organic waste to synthesize IAA hormones. Methods: The ecoenzyme was extracted from fruit powders and centrifuged to separate the supernatant. …”
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2008
Lipedema: diagnosis, treatment and the vicious cycle - a review of the literature
Published 2025-02-01“…It usually develops during a period of hormonal changes (puberty, pregnancy or menopause) and is often confused with lymphoedema or obesity, leading to a delay in correct diagnosis and the introduction of effective treatment. …”
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2009
Increased Chromosomal and Oxidative DNA Damage in Patients with Multinodular Goiter and Their Association with Cancer
Published 2017-01-01“…This study evaluates cytokinesis-block micronucleus cytome (CBMN-cyt) assay parameters and plasma 8-OHdG levels and their association with thyroid nodule size and thyroid hormones in patients with multinodular goiter. The study included 32 patients with multinodular goiter and 18 age- and sex-matched healthy controls. …”
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2010
Ball-milled synthesis of biochar-MOF nanocomposite for the concurrent recovery of mixed contaminants from wastewater
Published 2025-01-01“…The nanocomposite exhibited maximum adsorption capacities of 74.18–85.69 mgg−1 for heavy metals and 72.99–86.21 mgg−1 for steroidal hormones. Kinetic analysis showed the adsorption process followed a pseudo-second-order model. …”
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2011
Natural History of Metabolic Dysfunction-Associated Steatotic Liver Disease: From Metabolic Syndrome to Hepatocellular Carcinoma
Published 2025-01-01“…<i>Background</i>: Visceral fat distribution varies by gender, impacting MASLD development due to hormonal influences. Insulin resistance plays a central role in MASLD pathogenesis, exacerbated by high-fat diets and specific fatty acids, leading to hepatic steatosis. …”
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2012
New therapies in pulmonary arterial hypertension: Recent insights
Published 2025-03-01“…Finally, strategies that target the serotonin pathway, and other metabolic and hormonal pathways are described.This review includes both preclinical and clinical trial data that support efficacy, safety and the future potential of such therapies. …”
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2013
Central Interleukin-1β Suppresses the Nocturnal Secretion of Melatonin
Published 2016-01-01“…In vertebrates, numerous processes occur in a rhythmic manner. The hormonal signal reliably reflecting the environmental light conditions is melatonin. …”
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2014
Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway
Published 2017-01-01“…The transcriptional regulation of ANGPTL4 can be modulated by several transcription factors, including PPARα, PPARβ/δ, PPARγ, and HIF-1α, and nutritional and hormonal conditions. Several studies showed that high levels of ANGPTL4 are associated with poor prognosis in patients with various solid tumors, suggesting an important role in cancer onset and progression, metastasis, and anoikis resistance. …”
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2015
Type 1 Diabetes Mellitus in Saudi Arabia: A Soaring Epidemic
Published 2018-01-01“…More alarmingly, the incidence of T1DM among infants is also increasing, with children as young as 6 months succumbing to it, instead of that at a rather established vulnerable age of around seven and near puberty, when the hormones antagonize the action of insulin. These reports pose a unique challenge of developing efficient T1DM management system for the young children. …”
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2016
Urinary Concentrations of Steroids in Bulls under Anabolic Treatment by Revalor-XS® Implant
Published 2016-01-01“…The aim of the research was to measure the residual urinary concentrations of the administered drugs (β-trenbolone and β-estradiol), their main metabolites (α-trenbolone and α-estradiol), and possible alterations of the urinary profile of other endogenous hormones metabolically related. The analytical method was based on liquid chromatography-tandem mass spectrometry. …”
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2017
A scoping review on heat indices used to measure the effects of heat on maternal and perinatal health
Published 2024-04-01“…Negative birth outcomes can occur from change in hormonal levels (ie, cortisol), dehydration and blood flow diversion away from the placenta and fetus when suffering from heat stress. …”
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2018
Inflammatory Pain and Corticosterone Response in Infant Rats: Effect of 5-HT1A Agonist Buspirone Prior to Gestational Stress
Published 2013-01-01“…Chronic treatments of rat dams with buspirone before restraint stress during gestation normalize in the offspring pain-like behavior and induce during the acute phase in the formalin test the stronger corticosterone increase as compared to the stress hormonal elevation in animals with other prenatal treatments. …”
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2019
Idiopathic multicentric Castleman disease in children: a single-center retrospective analysis
Published 2025-01-01“…Anti-IL-6-based therapy combined with hormones lenalidomide and other medications have a specific therapeutic effect on multicentric CD.…”
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2020
Using insecticidal compounds to elucidate the potential role of neurotransmitters in Lepidoptera pupal ecdysis
Published 2025-02-01“…Further studies are needed to elucidate the interplay between neuroendocrine hormones and neurotransmitters in lepidopteran pupal ecdysis.…”
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