SHP2-Mediated Signal Networks in Stem Cell Homeostasis and Dysfunction by Chen Kan, Fan Yang, Siying Wang

“…Stem cells, including embryonic stem cells (ESCs) and adult stem cells, play a central role in mammal organism development and homeostasis. They have two unique properties: the capacity for self-renewal and the ability to differentiate into many specialized cell types. …”
Get full text

Dendrobium species regulate energy homeostasis in neurodegenerative diseases: a review by Feixuan Wang, Jingqiong Wan, Yangzhen Liao, Shangyu Liu, Yuan Wei, Zhen Ouyang

Subjects: Get full text

Targeting ion homeostasis in metabolic diseases: Molecular mechanisms and targeted therapies by Yanjiao Zhang, Kaile Ma, Xinyi Fang, Yuxin Zhang, Runyu Miao, Huifang Guan, Jiaxing Tian

Subjects: “…Ion homeostasis…”
Get full text

Bioactive Compounds from Propolis on Bone Homeostasis: A Narrative Review by Vanessa Bertolucci, André Felipe Ninomiya, Giovanna Barbarini Longato, Luisa Oliveira Kaneko, Nilson Nonose, Pedro Paulo Menezes Scariot, Leonardo Henrique Dalcheco Messias

“…This regulation mitigates excessive osteoclast formation, stimulates osteoblast activity, and ultimately contributes to the restoration of bone homeostasis by maintaining a balanced bone remodeling process.…”
Get full text

Loss of flavonoids homeostasis leads to pistillody in sua-CMS of Nicotiana tabacum by Jie Xu, Zhuo Wei, Jugou Liao, Keliang Tao, Junpeng Zhang, Yu Jiang, Yongzhi Niu, Yunye Zheng, Limeng Zhang, Xuemei Wei

Get full text

Exerkines and Sarcopenia: Unveiling the Mechanism Behind Exercise-Induced Mitochondrial Homeostasis by Jiayin Wang, Dandan Jia, Zhiwang Zhang, Dan Wang

Subjects: Get full text

Immune Homeostasis in Epithelial Cells: Evidence and Role of Inflammasome Signaling Reviewed by Paul M. Peeters, Emiel F. Wouters, Niki L. Reynaert

“…This review compiles a vast amount of literature that supports a pivotal role for inflammasomes in the various epithelial barriers of the human body as essential factors maintaining immune signaling and homeostasis.…”
Get full text

PPARγ Signaling Mediates the Evolution, Development, Homeostasis, and Repair of the Lung by Virender K. Rehan, John S. Torday

“…Epithelial-mesenchymal interactions mediated by soluble growth factors determine the evolution of vertebrate lung physiology, including development, homeostasis, and repair. The final common pathway for all of these positively adaptive properties of the lung is the expression of epithelial parathyroid-hormone-related protein, and its binding to its receptor on the mesenchyme, inducing PPARγ expression by lipofibroblasts. …”
Get full text

From Homeostasis to Neuroinflammation: Insights into Cellular and Molecular Interactions and Network Dynamics by Ludmila Müller, Svetlana Di Benedetto, Viktor Müller

“…This perspective aims to enhance our understanding of neuroimmune communication and the mechanisms underlying shifts from homeostasis to neuroinflammation. Applying an MLN approach offers a more integrative view of CNS resilience and adaptability, helping to clarify inflammatory processes and identify novel intervention points within the layered landscape of neuroinflammatory responses.…”
Get full text

Innate Lymphoid Cells: Regulators of Gut Barrier Function and Immune Homeostasis by Hui Fan, Aiyun Wang, Yuan Wang, Ye Sun, Jing Han, Wenxing Chen, Shijun Wang, Yuanyuan Wu, Yin Lu

“…Recently, accumulating evidence supports that ILCs are vital regulators for gastrointestinal mucosal homeostasis through interactions with other structural and stromal cells in gut epithelial barriers. …”
Get full text

Transcriptome analysis reveals effects of ethynylestradiol and bisphenol A on multiple endocrine and metabolic pathways in the pituitary and liver of female Atlantic cod (Gadus mor... by Fekadu Yadetie, Xiaokang Zhang, Anna Reboa, Gwenaëlle Samantha Chloe Noally, Mariann Eilertsen, Mitchell Stewart Fleming, Jon Vidar Helvik, Inge Jonassen, Anders Goksøyr, Odd André Karlsen

Subjects: Get full text

Cognitive disorders: Potential astrocyte-based mechanism by Shiyu Li, Yeru Chen, Gang Chen

Subjects: “…Astrocytic homeostasis…”
Get full text

Excitatory-inhibitory homeostasis and bifurcation control in the Wilson-Cowan model of cortical dynamics. by Francisco Páscoa Dos Santos, Paul F M J Verschure

“…However, computational studies on E-I homeostasis have focused solely on the plasticity of inhibition, neglecting the impact of different modes of E-I homeostasis on cortical dynamics. …”
Get full text

Role of copper homeostasis and cuproptosis in heart failure pathogenesis: implications for therapeutic strategies by Zhichao Liu, Yongkang Gan, Zhen Shen, Siqi Cai, Xizhen Wang, Yong Li, Xiaofeng Li, Huanjie Fu, Jinhong Chen, Ningcen Li

Subjects: Get full text

Tubular MYDGF Slows Progression of Chronic Kidney Disease by Maintaining Mitochondrial Homeostasis by Xiaohan Liu, Yang Zhang, Youzhao Wang, Yujie Yang, Zhe Qiao, Ping Zhan, Huiying Jin, Qianqian Xu, Wei Tang, Yu Sun, Yan Zhang, Fan Yi, Min Liu

Subjects: Get full text

Asparagine endopeptidase regulates lysosome homeostasis via modulating endomembrane phosphoinositide composition by Linli Yao, GuangHui Zi, Miao He, Yuhong Xu, Lulu Wang, Baowei Peng

Get full text

Mesenchymal Stromal Cells and Tissue-Specific Progenitor Cells: Their Role in Tissue Homeostasis by Aleksandra Klimczak, Urszula Kozlowska

“…This paper is presenting an overview of the current knowledge of biology of tissue-resident mesenchymal stromal and progenitor cells (originated from bone marrow, liver, skeletal muscle, skin, heart, and lung) associated with tissue regeneration and tissue homeostasis.…”
Get full text

Delineating Molecular Mechanisms of Squamous Tissue Homeostasis and Neoplasia: Focus on p63 by Kathryn E. King, Linan Ha, Tura Camilli, Wendy C. Weinberg

“…Mouse models have informed us that p63 is critical for normal epidermal development and homeostasis. The p53/p63/p73 family is expressed as multiple protein isoforms due to a combination of alternative promoter usage and C-terminal alternative splicing. …”
Get full text

Function of Dicer with regard to Energy Homeostasis Regulation, Structural Modification, and Cellular Distribution by Xiaohui Tong, Nianjun Yu, Rongchun Han, Tongsheng Wang

“…The close relationship between Dicer levels and fluctuations of nutrient availability suggests that the protein participates in the regulation of systemic energy homeostasis. Through miRNAs, Dicer regulates the hypothalamic melanocortin-4 system and central autophagy promoting energy expenditure. …”
Get full text

Genetic predisposition to altered blood cell homeostasis is associated with glioma risk and survival by Linda Kachuri, Geno A. Guerra, Taishi Nakase, George A. Wendt, Helen M. Hansen, Annette M. Molinaro, Paige Bracci, Lucie McCoy, Terri Rice, John K. Wiencke, Jeanette E. Eckel-Passow, Robert B. Jenkins, Margaret Wrensch, Stephen S. Francis

Get full text