Inhalative IL-10 Attenuates Pulmonary Inflammation following Hemorrhagic Shock without Major Alterations of the Systemic Inflammatory Response by Philipp Kobbe, Philipp Lichte, Helen Schreiber, Lucy Kathleen Reiss, Stefan Uhlig, Hans-Christoph Pape, Roman Pfeifer

“…Acute pulmonary inflammation was assessed by pulmonary myeloperoxidase (MPO) activity and pulmonary H&E histopathology. Inhalative IL-10 administration decreased pulmonary inflammation without altering the systemic concentrations of IL-6, IL-10, and KC. …”
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Orally administered live BCG and heat-inactivated Mycobacterium bovis protect bison against experimental bovine tuberculosis by Nirajan Niroula, Priya Ghodasara, Nelson Marreros, Bailey Fuller, Haley Sanderson, Slim Zriba, Stew Walker, Todd K. Shury, Jeffrey M. Chen

“…To this end, we aerosol challenged young bison with different doses of virulent M. bovis and observed disease-associated delayed-type hypersensitivity, gross lung and lymph node pathology and histopathology, as well as M. bovis burden in target organs, thus confirming the establishment of BTB in challenged animals. …”
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Bilateral inverted papilloma: Case report and literature review by Mohammed Amine Rabhi, Achraf Amine Sbai, Drissia Benfadil, Azzedine Lachkar, Adil Abdenbi Tsen, Fahd Elayoubi

“…Imaging (CT and MRI) showed a cerebriform mass extending through the nasal cavities and into the nasopharynx, causing bone destruction without intracranial or intra-orbital spread. Histopathology confirmed a bilateral inverted papilloma without malignancy. …”
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Case study of a neuroendocrine tumor of uncertain origin: single-cell transcriptomics unravels potential primary location by Frolova Tatyana, Ekaterina Avsievich, Diana Salimgereeva, Zoia Antysheva, Alesia Maluchenko, Denis Maksimov, Ilia Feidorov, Mark Voloshin, Olga Glazova, Natalia Bodunova, Nikolay Karnaukhov, Pavel Volchkov, Julia Krupinova

“…Methods Initial diagnostic methods, including imaging and histopathology, failed to resolve the tumor’s origin. …”
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PGC1α Activators Mitigate Diabetic Tubulopathy by Improving Mitochondrial Dynamics and Quality Control by So-Young Lee, Jun Mo Kang, Dong-Jin Kim, Seon Hwa Park, Hye Yun Jeong, Yu Ho Lee, Yang Gyun Kim, Dong Ho Yang, Sang Ho Lee

“…AICAR and metformin treatment effectively mitigated albuminuria and renal histopathology and decreased the expression of TGFβ1 and αSMA in the kidneys of diabetic mice. …”
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Significance of N-terminal pro-B-type natriuretic peptide levels in lung cancer by Sinem İnan, Semra Bilaçeroğlu, Burcu Uludağ Artun

“…In this study, we aimed to investigate the significance of the correlation of NT-proBNP levels in lung cancer with tumor stage, tumor diameter, histopathology, and specific sites of mediastinal metastasis: lymphadenopathy; pericardial, cardiac, major vessel, other mediastinal organ or lymphatic involvement/invasion. …”
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The impact of particle size of nanostructured lipid carriers on follicular drug delivery: A comprehensive analysis of mouse and human hair follicle penetration by Saman Heydari, Mohammad Barzegar-Jalali, Mostafa Heydari, Afsaneh Radmehr, Ana Cláudia Paiva-Santos, Maryam Kouhsoltani, Hamed Hamishehkar

“…Biopsies were taken from applied areas on different days after using the formulation. The histopathology studies were done on the skin biopsies of both groups using confocal laser scanning microscopy (CLSM). …”
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Open resection and reconstruction of a Nasoseptal Chondrosarcoma: case report and literature review by Changseok Lee, David Forner, Martin Bullock, Matthew H. Rigby, Martin Corsten, Jonathan R. Trites, S. Mark Taylor

“…Biopsy of the cartilaginous lesion confirmed the diagnosis of a low-grade chondrosarcoma by histopathology. The tumour was removed using a transcolumellar open rhinoplasty approach with a large septal resection. …”
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Protective Effects of Necrostatin-1 against Concanavalin A-Induced Acute Hepatic Injury in Mice by Yingqun Zhou, Weiqi Dai, Chunlei Lin, Fan Wang, Lei He, Miao Shen, Ping Chen, Chenfen Wang, Jie Lu, Ling Xu, Xuanfu Xu, Chuanyong Guo

“…Amelioration in liver functions and histopathological changes and the suppression of inflammatory cytokine production were observed in Nec-1-injected mice. …”
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Clinicopathological Analysis and Surgical Outcome of Eyelid Malignancies: A Study of 332 Cases by Syeed Mehbub Ul Kadir, Mukti Rani Mitra, Riffat Rashid, Murtuza Nuruddin, Md. Kamrul Hassan Khan, Golam Haider, Mst. Sayedatun Nessa

“…All patients were managed by surgical excision with tumor-free margins verified on histopathology, either the frozen section or excision biopsy with 2–3 mm microscopic view of normal tissue followed by eyelid reconstruction. …”
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Dietary Nannochloropsis oculata ameliorates lead acetate induced reproductive toxicity in Barki rams: NF-κB and cytokines pathways by Doaa H. Elsayed, Sameer A. Nagadi, Heba M.A. Abdelrazek, Ahmed. S. El‑Hawy, Moharram F. El-Bassiony, Seham A. Helmy, Yasmina K. Mahmoud, Ibrahim E. Helal, Shady T. Hassan

“…Alga supplementation to lead-intoxicated rams significantly upgraded the lead induced alterations that were manifested by improvement in testicular histopathology. In conclusion, the addition of alga mitigated lead induced reproductive toxicity in rams via improving testosterone, oxidant/antioxidant status, semen criteria and reducing inflammatory cytokines.…”
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Differential expressed genes (DEGs) and differential alternative splicing genes (DASs) revealed the common pathologic mechanism of three bacterial pathogens to American eels (Angui... by Zihao Chen, Guanghua Sun, Songlin Guo

“…This study provides new insights into the common pathological mechanisms of three bacterial pathogens, as revealed by histopathology, DEGs, and DASs.…”
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A Rare Case of Arteriovenous Hemangioma Clinically Mimicking Pigmented Nevus by Sri Lestari, Tofrizal ., Yenny Raflis

“…Physical examination: there is a solitare black papule, with 0,3x0,4 mm, round shape, fine scales, well defined, regular border with irreguler surface.<br />Histopathology findings: the lesions consist of thicked-walled and very dilated thin-walled vessels that full-filled with erythrocytes and are lined by an endothelial layer that suitable for AH. …”
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Sarcomatous tumor with external iliac vein aneurysm: a rare entity by Tushar Kalekar, Neeha Amit Jhala, Reetika Kapoor, Eshan Chetan Durgi, Karishma Krishnani

“…These findings were confirmed by contrast-enhanced arteriography, venography, and histopathology. The condition was diagnosed as soft tissue sarcoma and was treated accordingly. …”
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Learning by making – student-made models and creative projects for medical education: systematic review with qualitative synthesis by Tan Yong Yi, Panwar Shreyans, Ranganath Vallabhajosyula

“…These studies implemented various creative project interventions such as handicraft models, drawings, and concept maps covering multiple topics, including anatomy, histopathology, and fundamental sciences. The identified themes of Enhanced Learning, Collaborative Learning, and Deep Learning led to further themes of Student Engagement, Student Disengagement, and Faculty Engagement. …”
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HuoXueTongFu Formula Alleviates Intraperitoneal Adhesion by Regulating Macrophage Polarization and the SOCS/JAK2/STAT/PPAR-γ Signalling Pathway by Min Zhao, Yao-Yao Bian, Li-Li Yang, Yan-Qi Chen, Ya-Jie Wang, Yan-Ting Ma, Yu-Qiong Pei, Wen-Lin Li, Li Zeng

“…RAW264.7 cells were given LPS, IFN-γ, IL-4, HXTF-medicated serum, and PPAR-γ agonist/antagonist, respectively. Histopathology, flow cytometry, ELISA, real-time PCR, and Western blotting were used to further detect the related protein, M1/M2 polarization tendency, and PPAR-γ nuclear translocation. …”
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Bovine Tuberculosis in a Nebraska Herd of Farmed Elk and Fallow Deer: A Failure of the Tuberculin Skin Test and Opportunities for Serodiagnosis by W. Ray Waters, Gary E. Stevens, Mark A. Schoenbaum, Kathy A. Orloski, Suelee Robbe-Austerman, N. Beth Harris, S. Mark Hall, Bruce V. Thomsen, Arach J. Wilson, Roger E. Brannian, Jeffrey T. Nelson, Shawn Schafer, Javan Esfandiari, Meghan Dutton, Rena Greenwald, Konstantin P. Lyashchenko

“…Upon depopulation of the herd, the prevalence of bovine tuberculosis (TB) was estimated at ∼71–75%, based upon histopathology and culture results. Particularly with elk, gross lesions were often severe and extensive. …”
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Acute and prolonged toxicity assessment of Cannabis sativa extract in rodents and lagomorphs by Alana C. Costa, Arquimedes Gasparotto, Jr., Alana A.K. Garcia, Cícero A.C. Pereira, Emerson L.B. Lourenço, Helena P.G. Joaquim

“…Prolonged administration of 6 months in rats and 9 months in rabbits did not lead to significant changes in organ histopathology, body weight, or behavior. Although liver enzymes were elevated at the highest doses, other biochemical and hematological parameters remained unchanged. …”
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Proteomic profiling of Labeo rohita intestine infected with Edwardsiella tarda: Unveiling the mucosal defense mechanisms, cell adhesion, and cytoskeletal pathways by Nevil Pinto, Mehar Un Nissa, Gowhar Iqbal, Yashwanth BS, Darshan P, Sanjeeva S, Mukunda Goswami

“…Method: In our study, Labeo rohita was infected with Edwardsiella tarda for 48 h. Histopathology was performed to overview changes in rohu intestine. …”
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Bellini Duct Carcinoma Misdiagnosed with Urothelial Papillary Carcinoma by Joey El Khoury, Maher Abdessater, Rami Halabi, Fadi Nasr, Johnny Boustany, Anthony Kanbar, Charbel El Hachem, Raghid El Khoury

“…Corresponding early imaging and histopathology exams are primordial for a correct diagnosis and thus a better prognosis.…”
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