Interferon-free therapy of chronic hepatitis C: replacement of medications or new treatment paradigm? by S. N. Batskikh

Subjects: “…chronic hepatitis c…”
Get full text

Sarcoid-like reaction at the patient with chronic hepatitis C on a background of antiviral therapy by A. V. Lapshin, N. I. Kokina, M. V. Mayevskaya, I. A. Sokolina, V. T. Ivashkin

Subjects: Get full text

Russian interferon <i>α</i>-2b drug in the treatment of chronic hepatitis C by N. B. Kovaleva

Subjects: “…chronic hepatitis c…”
Get full text

Long-term results of antiviral therapy in patients with chronic hepatitis C with sustained virologic response by T. M. Ignatova, T. N. Lopatkina, V. P. Chulanov, Ye. V. Gaydasheva, S. N. Batskikh, G. V. Mikhaylovskaya, D. T. Abdurakhmanov, S. Yu. Karpov, Ye. N. Nikulkina, O. A. Chernova

Subjects: “…chronic hepatitis c…”
Get full text

The modern options of chronic hepatitis C antiviral therapy with daclatasvir: results of named patient program by V. T. Ivashkin, M. V. Mayevskaya, D. T. Abdurakhmanov, I. G. Bakulin, N. I. Geyvandova, M. L. Zubkin, S. N. Kizhlo, A. V. Kuznetsova, I. B. Latysheva, N. A. Mamonova, V. G. Morozov, O. I. Sagalova, Ye. V. Esaulenko, Ye. O. Lyusina

“…To analyze the efficacy of PTV for chronic hepatitis C within the named patient program of expanded access to daclatasvir. …”
Get full text

Polymorphism of renin — angiotensin system genes in progression of liver fibrosis in patients with chronic hepatitis C by O. V. Taratina, T. N. Krasnova, L. M. Samokhodskaya, T. N. Lopatkina, V. A. Tkachuk, N. A. Mukhin

Subjects: “…chronic hepatitis c…”
Get full text

Prevalence of resistance-associated substitutions (RAS) in hepatitis C virus in the Former Soviet Union countries by Sten H Vermund, Salima Davlidova, Syed Hani Abidi, Syed Ali, Robert Heimer, Aidana Mustafa, Dinara Begimbetova

“…Objective The emergence of resistance-associated substitutions (RASs) poses a significant challenge to the effective treatment of hepatitis C virus (HCV) infection using direct-acting antivirals. …”
Get full text

Long-Term Results of the Etiotropic Therapy of Subcompensed Liver Cirrhosis in the Outcome of Chronic Hepatitis C by P. O. Bogomolov, A. O. Bueverov, V. E. Bakirova, E. O. Lyusina, E. A. Fedosyina, S. V. Koblov, O. V. Sumtsova

Subjects: “…chronic hepatitis c…”
Get full text

Real-Life Experiences with Telaprevir in the Treatment of Chronic Genotype 1 Hepatitis C — The TEPS Study by T. Berg, P. Buggisch, D. Hueppe, S. Mauss, H. Wedemeyer, G. Teuber, T. Lutz, K. Stein, S. Wegner, H. Hinrichsen

Subjects: “…hepatitis c…”
Get full text

Pegilated interferon alpha 2b «Pegaltevir» chronic hepatitis C treatment (randomized clinical trial) by Marina V. Mayevskaya, Ye. N. Bessonova, P. O. Bogomolov, N. I. Geyvandova, K. V. Zhdanov, V. G. Morozov, V. D. Pasechnikov, I. Yu. Khomenko, A. V. Yagoda, V. T. Ivashkin

“…Nowadays the question, whether pegylated interferon should be completely abandoned in the treatment of chronic hepatitis C (CHC) is still open. Beneficial interferon properties include: absence of mutagenic capacity for hepatitis C virus and drug interaction, stimulation of host immune response. …”
Get full text

Differentiated approach at the choice of chronic hepatitis C antiviral therapy mode (real clinical practice experience) by I. Yu. Pirogova, N. B. Kovaleva, E. P. Patlusov, E. S. Radchenko

“…Overall 164 patients with hepatitis C viruses (HCV) genotypes 1, 2 and 3 in 4 medical centers received antiviral therapy. …”
Get full text

Clinical role of endothelial dysfunction and hemostasis gene allelic variants in hepatitis C virus-associated cryoglobulinemia by M. V. Sokolova, Ye. Ye. Starostina, T. N. Krasnova, L. M. Samokhodskaya, T. P. Rozina, V. G. Avdeyev, M. G. Artemova, Ye. B. Yarovaya, N. A. Mukhin

“…To estimate the effect of carriage of endothelial dysfunction and hemostasis gene allelic variants on development of cryoglobulinemic vasculitis (CryoVas) and its clinical symptoms in patients with chronic hepatitis C (CHC). Material and methods. Original study included overall 72 patients with CHC and cryoglobulinemia: 21 patients had CryoVas, 51 - CHC without vasculitis. …”
Get full text

Economic Evaluation of Boceprevir for the Treatment of Patients with Genotype 1 Chronic Hepatitis C Virus Infection in Hungary by Raymond Odhiambo, Jagpreet Chhatwal, Shannon Allen Ferrante, Antoine El Khoury, Elamin Elbasha

“…**Background:** Recent international, randomized, placebo-controlled clinical trials (SPRINT-2; RESPOND-2) demonstrated that the triple combination of peginterferon (PEG), ribavirin (RBV) and boceprevir (BOC) was more efficacious than the standard dual therapy of PEG and RBV in treatment of patients chronically infected with genotype 1 hepatitis C virus (HCV) infection. The objective of this study was to evaluate the cost-effectiveness of triple therapy in both treatment-naive and treatment-experienced patients in Hungary. …”
Get full text

Treatment of end-stages of liver disease in outcome of persistent hepatitis C virus infection at deficiency of donor organs by Ye. N. German, M. V. Mayevskaya, O. I. Andreytseva, V. T. Ivashkin, A. V. Chzhao, A. G. Serova, G. V. Mikhaylovskaya, I. Yu. Pirogova

“…To study the role of serological markers of hepatitis B virus infection: antibodies to hepatitis B virus cor-antigen (anti-HВcor IgG) in progressing liver damage at patients with persistent hepatitis C virus infection.Material and methods. For the first time in the large group of patients (2934) significant prevalence of serological markers of hepatitis B and C viruses among patients of versatile clinic was demonstrated.Results. …”
Get full text

NS5A replication complex inhibitor daclatasvir in the basis of chronic hepatitis C interferon-free therapy by M. V. Mayevskaya, M. S. Zharkova, V. T. Ivashkin

Subjects: “…chronic hepatitis c…”
Get full text

The clinical role of blood coagulation and platelet receptors gene allelic variants in development of cryoglobulinemic vasculitis at chronic hepatitis C by Yekaterina Ye. Starostina, M. V. Sokolova, L. M. Samokhodskaya, T. П. Rozina, T. N. Krasnova, Ye. B. Yarovaya, N. A. Mukhin

“…To estimate the clinical and prognostic value of carriage of various blood coagulation and platelet receptors gene allelic variants in development of cryoglobulinemic vasculitis at chronic hepatitis C (CHC). Material and methods. Original study included overall 200 patients with CHCs and liver cirrhosis in its outcome, who were divided into 3 groups: patients without cryoglobulinemia (CG, n=123), those with asymptomatic cryoglobulinemia (ACG, n=40) and with cryoglobulinemic vasculitis (CGV, n=37). …”
Get full text

Ocular manifestations and treatment safety in hepatitis C patients undergoing direct-acting antiviral therapy: a prospective cohort study by Guilherme Thomé de Carvalho, Carlos Eduardo Brandão Mello, Kelma Macedo Pohlmann Simões, Mário Martins dos Santos Motta, Max Kopti Fakoury, Bruno Vasconcelos Coimbra, Laura Gomes Nunes Melo, Flávio Mac Cord Medina

“…Methods: A prospective cohort study was conducted involving chronic hepatitis C patients undergoing direct-acting antiviral therapy. …”
Get full text

Peer-assisted telemedicine hepatitis-C treatment for people who use drugs in rural communities: a mixed methods study by Kim Hoffman, Gillian Leichtling, Sarah Shin, Andrew Seaman, Tonhi Gailey, Hunter C. Spencer, P. Todd Korthuis

“…Abstract Background The increase in opioid use disorder among young, nonurban people has fueled sharp rises in hepatitis C virus (HCV) infections. Innovative treatment models are needed that circumvent healthcare system barriers for people who use drugs (PWUD), particularly in rural areas. …”
Get full text

Safety and efficacy of telaprevir in treatment of a chronic hepatitis C in patients of the Russian population included in early access program study by D. T. Abrurakhmanov, V. G. Morozov, I. G. Nikitin, P. O. Bogomolov, N. I. Geyvandova, Ye. N. Bessonova, I. G. Bakulin, V. A. Isakov, K. V. Zhdanov, M. V. Mayevskaya, Ye. A. Nurmukhametova, E. Z. Burnevich, Ye. V. Chesnokov, V. D. Pasechnikov, A. Hill, I. Lonjon-Domanec, S. N. Kizhlo

“…In 153 patients with severe liver fibrosis caused by hepatitis C virus (genotype 1), on background of triple AVT with telaprevir high level of immediate virologic response and low level of the preterm treatment discontinuation was marked.…”
Get full text

Results of the ORION open comparative randomized trial: evaluation of efficacy of the Russian drugs Altevir and Phosphogliv in combined treatment of chronic hepatitis C by V. T. Ivashkin, M. V. Mayevskaya, P. O. Bogomolov, I. G. Nikitin, A. O. Buyeverov, A. V. Lapshin

Subjects: “…chronic hepatitis c…”
Get full text