Partial Replacement with Menhaden Oil Improves Peripheral Neuropathy in High-Fat-Fed Low-Dose Streptozotocin Type 2 Diabetic Rat by Lawrence J. Coppey, Amey Holmes, Eric P. Davidson, Mark A. Yorek

“…Menhaden oil did not improve elevated HbA1C levels or serum lipid levels but serum levels of adiponectin were significantly increased and hepatic steatosis was significantly improved. Diabetic rats were thermal hypoalgesic, had reduced motor and sensory nerve conduction velocities and intraepidermal nerve fiber profiles were decreased in the hindpaw and these endpoints were significantly improved with menhaden oil. …”
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Application of Dual Source Mono+Combined with Cinematic Rendering in Cirrhosis Portal Vein Imaging by Xiamin LI, Xiaoying HUANG, Zhifei LI, Fangkai GUO, Pengchao WANG, Chunhui SHAN

“…Among the results of 40 keV images, the CT and CNR values of the portal, spleen, and hepatic veins were higher than those of other images, and the differences were statistically significant. …”
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Downregulation of HBx Restrains Proliferation, Migration, and Invasion of HepG2 Cells by Chaoqun Huang, Wei Liu, Xiaochuan Zhao, Libin Zhao, Fuxiang Wang

“…Liver cancer is a major contributor to cancer-related death with poor survival for sufferers. Meanwhile, Hepatic B virus X protein (HBx) and XB130 are likely to participate in the pathogenesis of liver cancer. …”
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Effects of Exercise Training on Molecular Markers of Lipogenesis and Lipid Partitioning in Fructose-Induced Liver Fat Accumulation by Siham Yasari, Denis Prud'homme, Frédérique Tesson, Marek Jankowski, Jolanta Gutkowska, Emile Levy, Jean-Marc Lavoie

“…Fructose refeeding was associated with an increase in hepatic lipid content, endocannabinoid receptor 1, sterol regulatory element-binding protein1c, and stearoyl-CoA desaturase1 gene expression in both Sed and TR rats. …”
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Mixed Large Cell Neuroendocrine Carcinoma and Adenocarcinoma with Spindle Cell and Clear Cell Features in the Extrahepatic Bile Duct by John Wysocki, Rishi Agarwal, Laura Bratton, Jeremy Nguyen, Mandy Crause Weidenhaft, Nathan Shores, Hillary Z. Kimbrell

“…Cholangioscopy revealed a friable mass extending from the middle of the common bile duct to the common hepatic duct. A bile duct excision was performed. …”
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Atractylenolide I prevents acute liver failure in mouse by regulating M1 macrophage polarization by Hui Zhang, Min Gao, Haiyan Wang, Junfeng Zhang, Lin Wang, Guanjun Dong, Qun Ma, Chunxia Li, Jun Dai, Zhihua Li, Fenglian Yan, Huabao Xiong

“…Furthermore, the ATR-I pretreatment markedly suppresses M1 macrophage activation in hepatic mononuclear cells. In vitro experiments with bone marrow-derived macrophages indicate that ATR-I regulates macrophage polarization through the mitogen-activated protein kinase (MAPK) and interferon regulatory factor (IRF) signaling pathways. …”
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Cytopathologic, Histopathologic, and Immunohistochemical Features of Intrahepatic Clear Cell Bile Duct Adenoma: A Case Report and Review of the Literature by William W. Wu, Mai Gu, Di Lu

“…A 37-year-old morbidly obese woman was diagnosed with a 2.8 cm intrahepatic clear cell bile duct adenoma following segmental hepatic resection. Histochemical analysis of the tumor suggested the cause of cytoplasmic clearing in the neoplastic cells to be mucin and not glycogen or lipid. …”
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Expression and Function of Granzymes A and B in Escherichia coli Peritonitis and Sepsis by M. Isabel García-Laorden, Ingrid Stroo, Sanne Terpstra, Sandrine Florquin, Jan Paul Medema, Cornelis van´t Veer, Alex F. de Vos, Tom van der Poll

“…While gzm deficiency did not impact neutrophil recruitment into the abdominal cavity, it was accompanied by enhanced nucleosome release at the primary site of infection, earlier hepatic necrosis, and more renal dysfunction. These results suggest that gzms influence bacterial growth and the host inflammatory response during abdominal sepsis caused by E. coli.…”
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Safety Profile and Effects of Pulsed Methylprednisolone on Vital Signs in Thyroid Eye Disease by Kai-Ling Yong, Chiaw Ling Chng, Hla Myint Htoon, Lee Hooi Lim, Lay Leng Seah

“…No significant cardiovascular or hepatic toxicity was found. Conclusion. IVMP is relatively safe and efficacious. …”
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JTT-130, a Novel Intestine-Specific Inhibitor of Microsomal Triglyceride Transfer Protein, Improves Hyperglycemia and Dyslipidemia Independent of Suppression of Food Intake in Diab... by Shohei Sakata, Makoto Ito, Yasuko Mera, Tomohiko Sasase, Hiromi Yamamoto, Makoto Kakutani, Takeshi Ohta

“…JTT-130 treatment group showed improved glucose tolerance at 5 weeks after treatment and significant elevation of portal glucagon-like peptide-1 (GLP-1) levels. The hepatic lipid content in JTT-130 treatment group was decreased as compared with pair-fed group. …”
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The Effect of Cord Blood Bile Acid Levels on the Meconium Passage in Utero in Normal Pregnancies by Saynur Sarıcı Yılmaz, Deniz Hızlı, Yaprak Engin Üstün, Engin Yılmaz, Elif Gül Yapar Eyi, Leyla Mollamahmutoğlu

“…Exclusion criteria were: presence of any maternal disease, obstetric cholestasis, hepatic infections and multiple pregnancies. Sixty one pregnant women were recruited for the study: 31 women with meconium stained amnion liquid and 30 women with normal amnion liquid. …”
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Recovery of the Cell Cycle Inhibition in CCl4-Induced Cirrhosis by the Adenosine Derivative IFC-305 by Victoria Chagoya de Sánchez, Lidia Martínez-Pérez, Rolando Hernández-Muñoz, Gabriela Velasco-Loyden

“…Cirrhosis is a chronic degenerative illness characterized by changes in normal liver architecture, failure of hepatic function, and impairment of proliferative activity. …”
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Chronic effects of palm oil mill effluent on the hepatosomatic index of zebrafish (Danio rerio) by Zulfahmi Ilham, Setia Batubara Agung, Ali Rizwan, Wulandari Nasution Ayu, Puspita Bela, Nafis Badratun

“…Despite fluctuations during the study, such as an initial 20% increase in HSI in treatment A by day 7, the results indicate adaptive hepatic responses without significant toxic effects at the tested concentrations. …”
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Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study by Ramakrishna Pai Jakribettu, Rekha Boloor, Andrew Thaliath, Sharanya Yesudasan George, Thomas George, Manoj Ponadka Rai, Umran Rafique Sheikh, Kadke Shreedhara Avabratha, Manjeshwar Shrinath Baliga

“…Stratification based on NS1, IgG, and IgM showed significant alterations in the haematological, hepatic, and renal parameters. With respect to the treatment a small percentage of patients, that is, 8% (4 patients), required platelet transfusion as their counts went below 20,000/μL. …”
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Transient Neonatal Zinc Deficiency Caused by a Heterozygous G87R Mutation in the Zinc Transporter ZnT-2 (SLC30A2) Gene in the Mother Highlighting the Importance of Zn2+ for Normal... by Maria Consolata Miletta, Andreas Bieri, Kristin Kernland, Martin H. Schöni, Vibor Petkovic, Christa E. Flück, Andrée Eblé, Primus E. Mullis

“…Although term infants are born with an important hepatic Zn2+ storage, adequate Zn2+ nutrition of infants mostly depends on breast milk or formula feeding, which contains an adequate amount of Zn2+ to meet the infants’ requirements. …”
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LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis by Yasuka Matsunaga, Yusuke Nakatsu, Toshiaki Fukushima, Hirofumi Okubo, Misaki Iwashita, Hideyuki Sakoda, Midori Fujishiro, Takeshi Yamamotoya, Akifumi Kushiyama, Shin-ichiro Takahashi, Yoshihiro Tsuchiya, Hideaki Kamata, Fuminori Tokunaga, Kazuhiro Iwai, Tomoichiro Asano

“…Nonalcoholic steatohepatitis (NASH) is a disorder characterized by hepatic lipid accumulation followed by the inflammation-induced death of hepatocytes and fibrosis. …”
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Imaging Hepatocellular Carcinoma With Ga-Citrate PET: First Clinical Experience by Carina Mari Aparici MD, Spencer C. Behr MD, Youngho Seo PhD, R. Kate Kelley MD, Carlos Corvera MD, Kenneth T. Gao, Rahul Aggarwal MD, Michael J. Evans PhD

“…One patient with recurrent HCC was injected with 300 MBq of 68 Ga-citrate and imaged with PET/CT 249 minutes post injection. Four (28%) of 14 hepatic lesions were avid for 68 Ga-citrate. One extrahepatic lesion was not PET avid. …”
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Mechanistic insights toward progress in alogliptin beyond glycemic control: translational perspective by Faraha Ahmed, Syed Sufian Ahmad, M. Mumtaz Alam, M. Shaqiquzzaman, Abul Kalam Najmi, Mohammad Ahmed Khan

“…It has a good safety profile, well-tolerated in elderly patients and in patients with co-morbid conditions including risks of cardiovascular event, renal or hepatic insufficiency. Therefore, alogliptin is incessantly experimented and investigated for its therapeutic benefit. …”
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Mirizzi Syndrome with Cholecystobiliary Fistula: Observation of Development from Asymptomatic Cholecystolithiasis to Surgery by Hiroyuki Sugo, Yuuki Sekine, Naoki Iwanaga, Shigefumi Neshime, Michio Machida

“…CT conducted 6 months before the present admission revealed that the gallbladder stone was compressing the common hepatic duct, although the patient remained asymptomatic. …”
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Cannabinoid Receptor 1 Gene Polymorphisms and Nonalcoholic Fatty Liver Disease in Women with Polycystic Ovary Syndrome and in Healthy Controls by Justyna Kuliczkowska Plaksej, Lukasz Laczmanski, Andrzej Milewicz, A. Lenarcik-Kabza, Anna Trzmiel-Bira, Urszula Zaleska-Dorobisz, Felicja Lwow, Lidia Hirnle

“…Subjects. 173 women with PCOS (aged 20–35) and 125 healthy, age- and weight-matched controls were studied. Methods. Hepatic steatosis was assessed by ultrasound evaluation. …”
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