Comparison of Bone Mineral Density in Thalassemia Major Patients with Healthy Controls by Mahesh Chand Meena, Alok Hemal, Mukul Satija, Shilpa Khanna Arora, Shahina Bano

“…Chronic hemoglobinopathies like thalassemia are associated with many osteopathies like osteoporosis. …”
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Pyruvate Kinase Deficiency Causing Priapism by Vinay Hanyalu Shankar, Bharadwaj Adithya-Sateesh, Nicole Gousy, Girma Ayele, Freyr Petursson, Rediet Atalay, Miriam Michael

“…This differs greatly as priapism has been frequently reported in patients with other chronic hemoglobinopathies such as sickle cell disease, thalassemia, and G6PD with and without splenectomy. …”
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An algorithm to Detect Overlapping Red Blood Cells for Sickle Cell Disease Diagnosis. by Mabirizi, Vicent, Kawuma, Simon, Safari, Yonasi

“…In Africa, Uganda is among the countries with a high number of babies (20,000 babies)born with sickle cell, contributing between 6.8% of the children born with sickle cell every year worldwide and approximately 4.5% of the children born with hemoglobinopathies worldwide. It is estimated that by 2050, sickle cell cases will increase by 30% if no intervention is put in place. …”
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Role of B-Cell Lymphoma/Leukemia 11A in Normal and Malignant Hematopoiesis by Haihang Zhang, Junhao Zeng, Fangling Zhang, Jing Liu, Long Liang

“…B-cell lymphoma/leukemia 11A (BCL11A) is a crucial transcriptional regulator, widely recognized for its role in controlling fetal hemoglobin and its potential as a gene therapy target for inherited hemoglobinopathies. Beyond this, recent studies have also highlighted its key role in the maturation and function of immune cells and erythrocytes, mediated through the regulation of various molecules during hematopoietic development. …”
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Hyperhemolysis Syndrome without Underlying Hematologic Disease by Lauren Anne Eberly, Diaa Osman, Nathaniel Perryman Collins

“…This phenomenon, commonly described in sickle cell disease, is a rare occurrence in patients without hemoglobinopathies. Case Report. A 55-year-old male presented to the hospital after a motorcycle crash and received 10 units of cross-matched blood for active bleeding. …”
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Hemoglobin Variants as Targets for Stabilizing Drugs by Miroslava Žoldáková, Michal Novotný, Krishna P. Khakurel, Gabriel Žoldák

“…Continued research into hemoglobin stabilization and ligand-binding modification may yield more precise, effective treatments and pave the way toward effective strategies for hemoglobinopathies.…”
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An implementation trial to mAnage siCkle CELl disEase through incReased AdopTion of hydroxyurEa in Nigeria (ACCELERATE): Study protocol. by Emmanuel Peprah, Joyce Gyamfi, John Patena, Hazal Kayalioglu, Tania Hameed, Gbenga Ogedegbe, Hyungrok Do, Dike Ojji, Deborah Adenikinju, Tayo Ajaye Oba, Maxwell Nwegbu, Hezekiah Isa, Grace Shedul, Alayo Y Sopekan, Obiageli E Nnodu

“…<h4>Methods</h4>This study will implement the SIM intervention, encompassing patient screening, initiation of HU treatment, and maintenance of dosage, which will be implemented via the TAsk-Strengthening Strategy for Hemoglobinopathies (TASSH TCP), derived from our team's TAsk-Strengthening Strategy for Hypertension control (TASSH) trials. …”
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Dual α-globin-truncated erythropoietin receptor knockin restores hemoglobin production in α-thalassemia-derived erythroid cells by Simon N. Chu, Eric Soupene, Devesh Sharma, Roshani Sinha, Travis McCreary, Britney Hernandez, Huifeng Shen, Beeke Wienert, Chance Bowman, Han Yin, Benjamin J. Lesch, Kun Jia, Kathleen A. Romero, Zachary Kostamo, Yankai Zhang, Tammy Tran, Marco Cordero, Shota Homma, Jessica P. Hampton, James M. Gardner, Bruce R. Conklin, Tippi C. MacKenzie, Vivien A. Sheehan, Matthew H. Porteus, M. Kyle Cromer

“…By directing edited HSPCs toward increased production of clinically relevant erythroid cells, this approach has the potential to mitigate the limitations of current treatments for the hemoglobinopathies, including low genome editing and low engraftment rates.…”
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Hemoglobin Variant (Hemoglobin Aalborg) Mimicking Interstitial Pulmonary Disease by Vasiliki Panou, Peter-Diedrich Mathias Jensen, Jan Freddy Pedersen, Lars Pilegaard Thomsen, Ulla Møller Weinreich

“…Our index person was a healthy woman of 58, not previously diagnosed with hemoglobinopathy Aalborg, who developed acute respiratory failure after a routine cholecystectomy. …”
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Study of the Prevalence of Cytomegalovirus in Children with Malignancy in Southwestern Iran from 2016-2023 by Arash Alghasi, Saeed Bitraf, Roya Salehi Kahyesh, Yasin Alidadi, Homayoun Yousefi, Manouchehr Makvandi

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Hemophilia A Haplotypes in Southwestern Iran by Bizhen Keikhaei Dehdezi, Ali Khodadadi, Arta Farhadi Kia, Faezeh Abbasi, Saeed Bitraf, Roya Salehi Kahyesh

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Orbital Infarction due to Sickle Cell Disease without Orbital Pain by Cameron L. McBride, Kim-Binh T. Mai, Kartik S. Kumar

“…Sickle cell disease is a hemoglobinopathy that results in paroxysmal arteriolar occlusion and tissue infarction that can manifest in a plurality of tissues. …”
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Intestinal Parasites Infection in Children with Cancer in Ahvaz, Southwest Iran by Roya Salehi Kahyesh, Arash Alghasi, Shekoufe Haddadi, Asaad Sharhani

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Effect of L-carnitine on lipid biomarkers of oxidative stress in chronic hemodialysis patients: a randomized controlled trial by Shokoh Shayanpour, Seyyed Seyfollah Beladi Mousavi, Hossain Karimpourian, Khojasteh Hoseinynejad, Kambiz Ahmadi Angali

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Rare Case of Methemoglobinemia Complicating Pregnancy by S. Verma, P. Sachdeva, G. Gandhi

“…The outcomes and the results of our efforts to find the etiology of her reduced saturation on monitors despite being clinically asymptomatic lead to the disclosure of this rare hemoglobinopathy. Mother and baby had uneventful course after delivery and were discharged well.…”
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A Massive Extradural Hematoma in Sickle Cell Disease and the Importance of Rapid Neuroimaging by Per Ole Iversen, Mboka Jacob, Jamila Makame, Mclean Abisay, Mbonea Yonazi, Anna Schuh, Julie Makani

“…Sickle cell disease (SCD) is an inherited hemoglobinopathy leading to several serious organ complications and early death. …”
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Co-infection of SARS‐CoV‐2 and influenza A/B among patients with COVID-19: a systematic review and meta-analysis by Monireh Golpour, Hossein Jalali, Reza Alizadeh-Navaei, Masoumeh Rezaei Talarposhti, Tahoora Mousavi, Ali Asghar Nadi Ghara

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Iron Deficiency and Iron Deficiency Anemia Are Common Epidemiological Conditions in Saudi Arabia: Report of the National Epidemiological Survey by Tarek Owaidah, Nouf Al-Numair, Ayman Al-Suliman, Mohammed Zolaly, Rana Hasanato, Faisal Al Zahrani, Mohameed Albalawi, Layla Bashawri, Khawar Siddiqui, Faisal Alalaf, Abdulkareem Almomen, Muhammad Raihan Sajid

“…A total of 981 students completed the survey, with 11% of the participants reporting symptoms of anemia; 34% of participants were diagnosed with IDA and 6% reported a diagnosis of hemoglobinopathy. Blood analysis confirmed the prevalence of ID and IDA in 28.6% and 10.7% of the participants, respectively; those with ID and IDA were mostly females (88.5% and 94%, resp.). …”
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The added role of Doppler ultrasound evaluation of sickle cell disease vasculopathy as a state of arterial stiffness and decreased nitric oxide bioavailability by Marwa Mohammed Mohammed Onsy, Sonia Ali El-Saiedi, Douaa Mohammed Mohammed Elsheshtawy, Marwa Abd-Elhady Abd-Elsamad

“…Abstract Background Sickle cell disease is an inherited hemoglobinopathy resulting in chronic hemolysis and painful vaso-occlusive crises. …”
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COVID-19 Mortality in a Pediatric Patient with Hemoglobin SC Disease and Alpha-Thalassemia Trait by Joshua E. Motelow, Stacie Kahn, Patrick T. Wilson

“…Although children have significantly better outcomes than adults, providers must remain vigilant while treating any patient with a hemoglobinopathy in the setting of severe COVID-19.…”
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