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Advancing Multiple Myeloma Immunotherapy: A Review of Chimeric Antigen Receptor T-Cell and Bispecific T-Cell Engagers Cell Therapies in Revolutionizing Treatment
Published 2025-01-01“…Multiple Myeloma (MM) is a hematologic malignancy characterized by clonal plasma cell development, leading to serious complications. …”
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143
An Adult Patient with Systemic Mastocytosis and B-Acute Lymphoblastic Leukemia
Published 2014-01-01“…In a significant proportion of patients, systemic mastocytosis (SM) coexists with another hematologic malignancy, termed systemic mastocytosis with an associated hematologic nonmast cell lineage disorder (SM-AHNMD). …”
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144
The Dual Role of HLA-G in Cancer
Published 2014-01-01“…We here review the current data on the role of HLA-G in cancer based on recent findings of an unexpected antitumor activity of HLA-G in hematological malignancies. For the past decade, HLA-G has been described as a tumor-escape mechanism favoring cancer progression, and blocking strategies have been proposed to counteract it. …”
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145
Hypercalcemia, Anemia, and Acute Kidney Injury: A Rare Presentation of Sarcoidosis
Published 2015-01-01“…Our Initial impression was likely underlying hematologic malignancy such as lymphoma or multiple myeloma. …”
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146
Clinical Features and Outcome of Mucormycosis
Published 2014-01-01“…Ten patients had diabetes mellitus as the underlying disease, and 6 patients had a hematological malignancy (acute leukemia). Of the diabetic patients, 3 had chronic renal failure and 4 presented with diabetic ketoacidosis. …”
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147
Donor lymphocyte infusions: An experience from a tertiary care center of North India
Published 2024-01-01“…However, further evidence is required to evaluate its efficacy, especially in relapsed or residual hematological malignancies.…”
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148
MicroRNAs as Haematopoiesis Regulators
Published 2013-01-01“…Aberrant expression of miRNAs was observed in hematological malignancies including chronic myelogenous leukemia, chronic lymphocytic leukemia, multiple myelomas, and B cell lymphomas. …”
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149
Translating Unconventional T Cells and Their Roles in Leukemia Antitumor Immunity
Published 2021-01-01“…In recent years, these cell populations have been associated with a repertoire of anti- or protumor responses and play important roles in the dynamics of solid tumors and hematological malignancies, thus, encouraging the development of new investigations in the area. …”
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150
The Essential Thrombocythemia, Thrombotic Risk Stratification, and Cardiovascular Risk Factors
Published 2020-01-01“…Essential thrombocythemia is a rare hematological malignancy with good overall survival, but moderate to high risk of developing arterial or venous thrombosis lifelong. …”
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151
Rat Sarcoma Virus Family Genes in Acute Myeloid Leukemia: Pathogenetic and Clinical Implications
Published 2025-01-01“…Acute myeloid leukemias (AMLs) comprise a group of genetically heterogeneous hematological malignancies that result in the abnormal growth of leukemic cells and halt the maturation process of normal hematopoietic stem cells. …”
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152
The Effects of Forodesine in Murine and Human Multiple Myeloma Cells
Published 2010-01-01“…Multiple myeloma (MM) is the second most commonly diagnosed hematological malignancy, characterized by a monoclonal proliferation of malignant cells in the bone marrow. …”
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153
Mimicking Myelodysplastic Syndrome: Importance of Differential Diagnosis
Published 2021-01-01“…Copper deficiency is a rare nutritional deficiency with hematological manifestations that mimic those found in myelodysplastic syndrome, a hematological malignancy incurable without allogeneic hematopoietic stem cell transplantation. …”
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154
A Rare Cause of Acute Kidney Injury: Primary Renal Lymphoma in a Patient with Human Immunodeficiency Virus
Published 2018-01-01“…Acute kidney injury secondary to lymphoma infiltrates is very rare (less than 1% of hematological malignancy). A 37-year-old gentleman with underlying human immunodeficiency virus (HIV) disease was on combined antiretroviral therapy since diagnosis. …”
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155
Epigenetic Alterations in Bladder Cancer and Their Potential Clinical Implications
Published 2012-01-01“…The epigenetic abnormalities associated with UC would make it an excellent target for epigenetic therapy, which is currently approved for the treatment of a few hematological malignancies. Future research is needed to address efficacy and potential toxicity issues before it can be implemented as a therapeutic strategy for solid tumors.…”
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156
Exercise as an Adjuvant Therapy for Hematopoietic Stem Cell Mobilization
Published 2016-01-01“…Hematopoietic stem cell transplant (HSCT) using mobilized peripheral blood hematopoietic stem cells (HSPCs) is the only curative strategy for many patients suffering from hematological malignancies. HSPC collection protocols rely on pharmacological agents to mobilize HSPCs to peripheral blood. …”
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157
Cellular Mechanisms of Multiple Myeloma Bone Disease
Published 2013-01-01“…Multiple myeloma (MM) is a hematologic malignancy of differentiated plasma cells that accumulates and proliferates in the bone marrow. …”
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158
Notch/CXCR4 Partnership in Acute Lymphoblastic Leukemia Progression
Published 2019-01-01“…Recent advances in chemotherapy have made ALL a curable hematological malignancy. In children, there is 25% chance of disease relapse, typically in the central nervous system. …”
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159
Staphylococcal SSL5 Binding to Human Leukemia Cells Inhibits Cell Adhesion to Endothelial Cells and Platelets
Published 2010-01-01“…These data support the concept that SSL5 could be a lead in the search for novel strategies against hematological malignancies.…”
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Mitochondrial abnormalities as a target of intervention in acute myeloid leukemia
Published 2025-01-01“…Acute myeloid leukemia (AML) is an aggressive hematological malignancy; it is the most common acute leukemia in adults. …”
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