Addressing the “Black Hole” of Low Back Pain Care With Clinical Decision Support: User-Centered Design and Initial Usability Study by Robert S Rudin, Patricia M Herman, Robert Vining

“…User input led to key refinements in the design, such as organizing the input questions by microdiagnosis, adding a patient summary screen that persists during data input and when reviewing output, adding more information buttons and graphics to input questions, and providing traceability by highlighting the input items used by the clinical logic to suggest a working diagnosis. …”
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Factors affecting the design of the management dashboard framework with an emphasis on the components of human resources productivity by Hassan Barmaki, Farshad Faezy Razi, Ehtesham Rashidi

“…Of course, today, productivity is considered beyond a standard and as a culture and attitude to work and life, and according to economists and management thinkers, its improvement provides the main basis for economic development (Philip, 2017).Definition of organizational dashboardOrganizational dashboards are very suitable tools for graphically displaying evaluations. Today, many softwares have been created to provide organizational dashboards that can communicate with various databases and display the results of information graphically while performing computational operations (Su, 2020). …”
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Does diabetes modify the triglyceride–glucose index associated with cardiovascular events and mortality? A meta-analysis of 50 cohorts involving 7,239,790 participants by Jun Zhang, Qiye Zhan, Zhihao Deng, Ling Lin, Zhaolan Feng, Huabin He, Deju Zhang, Huilei Zhao, Xiang Gu, Xiaoping Yin, Peng Yu, Xiao Liu

“…Future studies should explore the role of diabetes in the TyG index-associated CVD outcomes and mortality. Graphical abstract…”
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Determining the status of tertiary lymphoid structures in invasive pulmonary adenocarcinoma based on chest CT radiomic features by Ye Yu, Tianshu Yang, Pengfei Ma, Yan Zeng, Yongming Dai, Yicheng Fu, Aie Liu, Ying Zhang, Guanglei Zhuang, Yan Zhou, Huawei Wu

“…This study supports individualized clinical decision-making for patients with IA. Graphical Abstract…”
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Multimodal data-based longitudinal prognostic model for predicting atrial fibrillation recurrence after catheter ablation in patients with patent foramen ovale and paroxysmal atria... by Shoupeng Duan, Xujun Li, Jun Wang, Yuhong Wang, Tianyou Xu, Fuding Guo, Yijun Wang, Lingpeng Song, Zeyan Li, Xiaomeng Yang, Xiaoyu Shi, Hengyang Liu, Liping Zhou, Yueyi Wang, Hong Jiang, Lilei Yu

“…(ChiCTR2300072320). Graphical Abstract…”
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APOE Christchurch enhances a disease-associated microglial response to plaque but suppresses response to tau pathology by Kristine M. Tran, Nellie E. Kwang, Claire A. Butler, Angela Gomez-Arboledas, Shimako Kawauchi, Cassandra Mar, Donna Chao, Rocio A. Barahona, Celia Da Cunha, Kate I. Tsourmas, Zechuan Shi, Shuling Wang, Sherilyn Collins, Amber Walker, Kai-Xuan Shi, Joshua A. Alcantara, Jonathan Neumann, Duc M. Duong, Nicholas T. Seyfried, Andrea J. Tenner, Frank M. LaFerla, Lindsay A. Hohsfield, Vivek Swarup, Grant R. MacGregor, Kim N. Green

“…This suggests that the Christchurch variant's protective effects likely involve multiple mechanisms, including changes in receptor binding and microglial programming. Graphical Abstract…”
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Characteristics of TSPO expression in marmoset EAE by Irene Falk, Dragan Maric, Emily Leibovitch, Pascal Sati, Jennifer Lefeuvre, Nicholas J. Luciano, Joseph Guy, Seung-Kwon Ha, David R. Owen, Franklin Aigbirhio, Paul M. Matthews, Daniel S. Reich, Steven Jacobson

“…Thus, marmoset EAE appears to be a clinically relevant model for the study of TSPO in immune dysregulation in human disease. Graphical Abstract…”
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Challenges and Strategies Adopted for Remote Teaching of Biochemistry During the COVID-19 Pandemic: Protocol for a Scoping Review by Tatiane Iembo, Helena Landim Gonçalves Cristóvão, Emerson Roberto dos Santos, André Bavaresco Gonçalves Cristóvão, Nathália Bavaresco Gonçalves Cristóvão, Cíntia Canato Martins, Natália Almeida de Arnaldo Silva Rodrigues Castro, Fernando Nestor Facio Júnior, Antônio Hélio Oliani, Alba Regina de Abreu Lima, Vânia Maria Sabadoto Brienze, Doroteia Rossi Silva Souza, Júlio César André

“…The findings from this review on biochemistry teaching strategies will be communicated using a combination of descriptive narrative, graphical, and tabular formats, emphasizing diverse pedagogical approaches pertinent to the subject. …”
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iMulch: an investigation of the influence of polymers on a terrestrial ecosystem using the example of mulch films used in agriculture by Carmen Wolf, Mike Wenzel, Björn Fischer, Ralf Bertling, Erich Jelen, Dieter Hennecke, Karlheinz Weinfurtner, Martina Roß-Nickoll, Henner Hollert, Antonia Weltmeyer, Kristina Bitter, Pauline Ruiz, Dusica Banduka, Jochen Tuerk, Lars M. Blank

“…For this purpose, a minimum lower limit for the material thickness should be defined. Graphical Abstract…”
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On the tracks of an uninvited guest, the Asian tiger mosquito, Aedes albopictus in Cyprus by Riccardo Piccinno, Giulia Fiorenza, Marlen Ines Vasquez, Jeremy Bouyer, Gregoris Notarides, Ludvik Marcus Gomulski, Soteris Meletiou, Mustafa Akiner, Antonios Michaelakis, Federico Forneris, Giovanni Maga, Giuliano Gasperi, Anna Rodolfa Malacrida

“…As the Balkan and Italian mosquitoes display high competence for CHIKV, questions arise about possible arbovirus outbreaks in Cyprus and highlight the need to implement surveillance and control measures. Graphical Abstract…”
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An updated systematic review with meta-analysis and meta-regression of the factors associated with human visceral leishmaniasis in the Americas by Anna Gabryela Sousa Duarte, Guilherme Loureiro Werneck, Sarah de Farias Lelis, Thays Santos Mendonça, Daniela Dias Vasconcelos, Tiago Silveira Gontijo, Álisson Oliveira dos Santos, Lucas Edel Donato, Vinícius Silva Belo

“…Future research should be conducted with greater statistical power and using molecular diagnostic techniques, preferably involving cohort studies in diverse Latin American countries. Graphical Abstract…”
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First clinical cases of leishmaniosis in meerkats (Suricata suricatta) housed in wildlife parks in Madrid, Spain by Pablo Moraleda-Berral, Rosa Gálvez, Eva Martínez-Nevado, Lino Pérez de Quadros, Juncal García, Manuel de la Riva-Fraga, Juan Pedro Barrera, Efrén Estévez-Sánchez, Lourdes Cano, Rocío Checa, María Ángeles Jiménez-Martínez, Ana Montoya, Guadalupe Miró

“…Conclusions To our knowledge, this study describes, for the first time, the detection and infection by L. infantum in meerkats (Suricata suricatta). Graphical Abstract…”
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Experimental infection of wild boars (Sus scrofa) with Rickettsia rickettsii and evaluation of the transmission potential to Amblyomma sculptum ticks by Lucianne Cardoso Neves, Lina de Campos Binder, Warley Vieira de Freitas Paula, Nicolas Jalowitzki de Lima, Ennya Rafaella Neves Cardoso, Rayane Almeida Santos, Raphaela Bueno Mendes Bittencourt, Gracielle Teles Pádua, Gabriel Cândido dos Santos, Mariana Avelar Tavares, Maria Carolina de Azevedo Serpa, Adriano Pinter, Artur Luiz de Almeida Felicio, Marcelo B. Labruna, Felipe da Silva Krawczak

“…Conclusions Wild boars seroconverted to Rickettsia spp. after being infested with R. rickettsii-infected A. sculptum; however, they did not develop bacteremia and did not act as competent amplifying hosts of R. rickettsii for A. sculptum ticks. Graphical Abstract…”
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First report of Haemaphysalis bispinosa, molecular-geographic relationships of Ixodes granulatus and a new Dermacentor species from Vietnam by Sándor Hornok, Jenő Kontschán, Gergő Keve, Nóra Takács, Dat Van Nguyen, Khanh Ngoc Phuong Ho, Tamás Görföl, Yuanzhi Wang, Róbert Farkas, Thanh Thi Ha Dao

“…., recognized and described here for the first time, was almost certainly misidentified previously as Dermacentor steini, drawing attention to the need to barcode all Dermacentor spp. in Southern Asia. Graphical Abstract…”
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Merck Open Global Health Library in vitro screening against Schistosoma mansoni identified two new substances with antischistosomal activities for further development by Monique Evelyn Ueberall, Martina Berchthold, Cécile Häberli, Sven Lindemann, Thomas Spangenberg, Jennifer Keiser, Christoph G. Grevelding

“…Conclusions In two independent in vitro screening approaches against two stages of S. mansoni one common interesting structure with rapid effects was identified, OGHL00022, which provides opportunities for further development. Graphical Abstract…”
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Vitamin D3/VDR alleviates double-stranded RNA virus -induced biliary epithelial cell damage by inhibiting autophagy by Na Liu, Pu Zhao, Ping Cao, JunPeng Hui, YongKang Pan, Jiwen Cheng

“…The 1,25-VD3/VDR/Src axis alleviated poly(I: C)-induced HIBEC damage and apoptosis through the PLA2/PKC/ERK pathway. Graphical abstract…”
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Comparative effect of atorvastatin and risperidone on modulation of TLR4/NF-κB/NOX-2 in a rat model of valproic acid-induced autism by Eman A. E. Farrag, Mona H. Askar, Zienab Abdallah, Safinaz M. Mahmoud, Eman A. Abdulhai, Eman Abdelrazik, Eman Mohamad El Nashar, Faten Mohammed Alasiri, Asma Nasser Saeed Alqahtani, Mamdouh Eldesoqui, Ali M. Eldib, Alshimaa Magdy

“…Atorvastatin could be a potential treatment for ASD. Graphical Abstract…”
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Development of a pediatric obstructive sleep apnea triage algorithm by D. S. Heath, H. El-Hakim, Y. Al-Rahji, E. Eksteen, T. C. Uwiera, A. Isaac, M. Castro-Codesal, C. Gerdung, J. Maclean, P. J. Mandhane

“…Children with 2+ tonsil sizes should be triaged to otolaryngology, while the remainder should be referred to a pediatric sleep specialist. Graphical abstract…”
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FABLDroid: Malware detection based on hybrid analysis with factor analysis and broad learning methods for android applications by Kazım Kılıç, İsmail Atacak, İbrahim Alper Doğru

“…However, deep learning methods contain a large number of parameters and have high memory consumption and are graphics card dependent architectures. To overcome these difficulties, a detection architecture using lightweight Broad learning method that provides high detection performance as an alternative to layer stacking found in deep structures is presented. …”
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Automatic segmentation model and machine learning model grounded in ultrasound radiomics for distinguishing between low malignant risk and intermediate-high malignant risk of adnex... by Lu Liu, Wenjun Cai, Feibo Zheng, Hongyan Tian, Yanping Li, Ting Wang, Xiaonan Chen, Wenjing Zhu

“…We used SHapley Additive exPlanations to interpret and visualize the model. Graphical Abstract…”
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