PLGA confers upon conventional nonfluorescent molecules luminescent properties to trigger 1O2-induced pyroptosis and immune response in tumors by Lan Zou, Rujing Wang, Mengnan Zhao, Yuke Li, Chen Sun, Jinjin Xie, Yan Chen, Qian Jing, Dandan Mi, Sanjun Shi

“…This discovery holds the potential to facilitate the application of light-controlled pyroptosis in antitumor therapy, marking a promising stride toward innovative approaches in cancer treatment. Graphical abstract…”
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Predictive value of preoperative pan-immune-inflammation value index in the prognosis of oral cancer patients undergoing radical resection by Weihai Huang, Yulan Lin, Enling Xu, Yanmei Ji, Jing Wang, Fengqiong Liu, Fa Chen, Yu Qiu, Bin Shi, Lisong Lin, Baochang He

“…Conclusions PIV is an independent predictor of prognosis in patients with oral squamous cell carcinoma, and a column-line graphical model based on PIV can effectively predict prognosis.…”
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First evidence of the effectiveness of a field application of RNAi technology in reducing infestation of the mite Varroa destructor in the western honey bee (Apis mellifera) by Francesca Bortolin, Emanuele Rigato, Sergio Perandin, Anna Granato, Laura Zulian, Caterina Millino, Beniamina Pacchioni, Franco Mutinelli, Giuseppe Fusco

“…This study supports the potential of RNAi as a promising alternative to chemical pesticides, offering a targeted, efficient and sustainable solution for managing V. destructor in honey bee populations. Graphical Abstract…”
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Extracellular vesicle surface engineering with integrins (ITGAL & ITGB2) to specifically target ICAM-1-expressing endothelial cells by Markus Bergqvist, Kyong-Su Park, Nasibeh Karimi, Lijuan Yu, Cecilia Lässer, Jan Lötvall

“…We conclude that LFA-1-expressing EVMyd88 may be a candidate suitable for delivering therapeutic peptides in inflammatory diseases associated with TLR-activation. Graphical Abstract…”
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Simultaneously delivery of functional gallium ions and hydrogen sulfide to endow potentiated treatment efficacy in chemo- and PARPi-resistant ovarian cancer by Sangsang Tang, Yangyang Li, Yifeng Fang, Mengyan Tu, Shenglong Wu, Yixuan Cen, Junfen Xu

“…Altogether, our results demonstrated a potentially safe and practical strategy by using Ga2S3-BSA NMs to combat drug resistance in platinum-resistant OC. Graphical Abstract…”
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Exploiting venom toxins in paratransgenesis to prevent mosquito-borne disease by Stephanie French, Rachael Da Silva, Janet Storm, Christida E. Wastika, India Cullen, Martijn ten Have, Grant L. Hughes, Cassandra M. Modahl

“…We postulate the potential to apply this principle to target arboviruses using antiviral toxin effectors. Graphical Abstract…”
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Interdependence Between River Aquifer Groundwater Flow and Temperature–Depth Profiles: Type Curves Based on Pi Theorem and Numerical Simulations by José Antonio Jiménez-Valera, Iván Alhama, Carlos Duque, David Labat

“…Experimental studies and numerical modeling have supported analytical solutions; these solutions have been proposed for specific cases in which the aim has been to understand discharge/recharge and aquifer characterization. In this study, new graphical solutions or type curves are provided to estimate the subsurface flow and thermal–mechanical parameters in anisotropic porous media. …”
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Targeting OAS3 for reversing M2d infiltration and restoring anti-tumor immunity in pancreatic cancer by Shaopeng Zhang, Ximo Xu, Kundong Zhang, Changzheng Lei, Yitian Xu, Pengshan Zhang, Yuan Zhang, Haitao Gu, Chen Huang, Zhengjun Qiu

“…In conclusion, OAS3 presents as a promising immune therapeutic target for reversing IL-10highVEGF-AhighM2d infiltration and restoring CD8+T cell-mediated anti-tumor immunity in pancreatic cancer. Graphical abstract…”
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Locally administered liposomal drug depot enhances rheumatoid arthritis treatment by inhibiting inflammation and promoting cartilage repair by Zongquan Zhang, Guan Wang, Zhuo Zhang, Xiaoya Liang, Guoshuang Wang, Maochang Xu, Xi Yang, Xiaolin Zhong, Chunhong Li, Meiling Zhou

“…Our findings provide a synergistic strategy for inhibiting inflammation and mitigating cartilage damage through local joint cavity injection, thereby enhancing the therapeutic efficacy of RA. Graphical Abstract…”
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The feasibility and safety of eustachian tube dilation with a standard endovascular balloon: a clinical pilot study by Valerie Dahm, Justin T. Lui, Soyeon Jung, Vincent Y. Lin, Joseph M. Chen, Trung N. Le

“…Trial registration The study was registered at clinicaltrials.gov; NCT04809753, initial release February 24th, 2021. Graphical Abstract…”
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Internet of things enabled parking management system using long range wide area network for smart city by Waheb A. Jabbar, Lu Yi Tiew, Nadiah Y. Ali Shah

“…Users are provided with real-time updates on parking availability via the accessible AllThingsTalk Maker graphical user interface. Additionally, the system operates independently, sustained by a solar-powered rechargeable battery. …”
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Nitrogen source orchestrates pH modulation and secondary metabolism in Trichoderma harzianum by Stefania Vitale, Felice Salzano, Alessia Staropoli, Roberta Marra, David Turrà, Matteo Lorito, Francesco Vinale

“…This understanding provides new strategies for optimizing biocontrol formulations by manipulating nitrogen sources and pH conditions to enhance both fungal fitness and beneficial metabolite production. Graphical Abstract…”
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Dental pulp stem cell-derived intracellular vesicles prevent orthodontic relapse by inhibiting PI3K/Akt/NF-κB-mediated osteoclast activity by Boyuan Peng, Ziwei Li, Yong Cheng, Henghua Jiang, Qingsong Ye, Guangli Han

“…Conclusion This study highlights the potential of DPSC-IV as a novel preventive approach against orthodontic relapse, offering a novel strategy for maintaining long-term orthodontic stability. Graphical Abstract…”
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Sample size calculations based on day-to-day variability of stress biomarkers in persons with dementia and their family caregivers by Azita Emami, Jeehye Jun, Gabriella Engström, Lars Berglund, Töres Theorell

“…From this data, we created formulas and graphical tools for the number of required sampling days needed to detect effect differences, and we calculated number of days needed for regression coefficients to be estimated with<10% bias. …”
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Challenges in safe environmental applications of biochar: identifying risks and unintended consequence by Mingying Dong, Mengyuan Jiang, Lizhi He, Zirun Zhang, Williamson Gustave, Meththika Vithanage, Nabeel Khan Niazi, Bo Chen, Xiaokai Zhang, Hailong Wang, Feng He

“…Additionally, this review summarizes the environmental risk assessment methods of biochar, providing a reference for its safe application and the sustainable development of biochar-related research. Graphical Abstract…”
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Complexity of near-surface deformation and subsurface structure of the Chihshang creeping fault-line scarp, eastern Taiwan: insights from integration of geological and geophysical... by W. J. Huang, M. T. Fitrianto, C. C. Chen, P. Y. Chang, I. C. Yen, M. Le Béon, S. T. Lu

“…Great caution is needed in the interpretation of the aseismic surface ruptures along the inferred trace of reverse creeping faults as fault branching. Graphical Abstract…”
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Categorizing and Determining of BI-RAD Breast Cancer Score by Using Deep Learning Techniques by Azhar Kassem Flayeh, Ali Douik

“…This study used a laptop with the following specifications: an Intel Core i7 CPU, 16GB of RAM, and Intel RTX integrated graphics. …”
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The pharmacology, toxicology, and detoxification of Aconitum kusnezoffii Reichb., traditional and modern views by Kenneth Happy, Sungyu Yang, Chang Ho Kang, Youngmin Kang

“…Further research is recommended to evaluate the quality of medicinal materials, understanding the herb’s pharmacodynamic substances, and assess long-term toxicity and clinical efficacy. Graphical Abstract…”
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Developing an activated biochar-mineral supplement for reducing methane formation in anaerobic fermentation by Sara Tahery, Mariano C. Parra, Paul Munroe, David R. G. Mitchell, Sarah J. Meale, Stephen Joseph

“…The supplement assisted with reducing the concentration of dissolved mineral nutrients, such as P and Mg, when included at 4.0% and 6.0% DM (P < 0.05). Graphical abstract…”
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Ciliary peristalsis flow of hydromagnetic Sutterby nanofluid through symmetric channel: Viscous dissipation in case of variable electrical conductivity by Sameh A. Hussein, Sameh E. Ahmed, Anas A.M. Arafa

“…To carry out the numerical computations and produce graphical solutions, an appropriate algorithm is created and is referred to as the built-in command ND-Solve via computational software known as Mathematica. …”
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