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  1. 16681

    Electrocardiographic signs of cardiac ischemia at rest and during exercise in patients with COPD traveling to 3,100 m: data from a randomized trial of acetazolamide by Marla Christen, Marla Christen, Aline Buergin, Aline Buergin, Maamed Mademilov, Maamed Mademilov, Laura Mayer, Laura Mayer, Simon R. Schneider, Simon R. Schneider, Mona Lichtblau, Mona Lichtblau, Talant M. Sooronbaev, Talant M. Sooronbaev, Silvia Ulrich, Silvia Ulrich, Konrad E. Bloch, Konrad E. Bloch, Michael Furian, Michael Furian

    Published 2025-02-01
    “…We assessed electrocardiogram (ECG)-derived signs of cardiac ischemia and the effects of preventive acetazolamide therapy in COPD patients traveling to high altitudes.MethodsPatients with COPD [Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) grades 2–3] and a predicted forced expiratory volume in 1 s (FEV1) of 66 ± 11% (mean ± SD), aged 57 ± 8 years, and living <1,000 m were included in this analysis of secondary outcomes from a randomized placebo-controlled double-blind trial (www.clinicaltrials.gov, NCT03156231). …”
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  2. 16682

    Evaluating the effectiveness of handheld ultrasound in primary blast lung injury: a comprehensive study by Shifeng Shao, Zhengbin Wu, Jun Liu, Zhikang Liao, Yuan Yao, Liang Zhang, Yaoli Wang, Hui Zhao

    Published 2025-01-01
    “…Abstract The incidence of blast injuries has been rising globally, particularly affecting the lungs due to their vulnerability. …”
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  3. 16683

    Comprehensive analysis of antimicrobial resistance dynamics among broiler and duck intensive production systems by Zsombor Szoke, Peter Fauszt, Maja Mikolas, Peter David, Emese Szilagyi-Tolnai, Georgina Pesti-Asboth, Judit Rita Homoki, Ildiko Kovacs-Forgacs, Ferenc Gal, Laszlo Stundl, Levente Czegledi, Aniko Stagel, Sandor Biro, Judit Remenyik, Melinda Paholcsek

    Published 2025-02-01
    “…Abstract Antimicrobial resistance (AMR) is a global health challenge requiring cross-sector action, with research largely focused on chickens, leaving ducks underexplored. …”
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  4. 16684

    Correlation analysis of the impact of Clonorchis sinensis juvenile on gut microbiota and transcriptome in mice by Xueling Deng, Shitao Li, Yuhong Wu, Jiali Yao, Wei Hou, Jiangyao Zheng, Boying Liang, Xiaole Liang, Qiping Hu, Zhanshuai Wu, Zeli Tang

    Published 2025-02-01
    “…ABSTRACT Clonorchiasis remains a non-negligible global zoonosis, imposing serious socio-economic burdens in endemic regions. …”
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  5. 16685

    Ligilactobacillus salivarius LZZAY01 accelerated autophagy and apoptosis in colon cancer cells and improved gut microbiota in CAC mice by Wenhong Yang, Tao Li, Shixiang An, Rong Chen, Yuxin Zhao, Jiaxian Cui, Mingyu Zhang, Jingkun Lu, Yunpeng Tian, Lili Bao, Pengwei Zhao

    Published 2025-02-01
    “…ABSTRACT Colorectal cancer (CRC) is one of the malignant tumors globally, with high morbidity and mortality rates. …”
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  6. 16686

    Delivery determinants of an Acinetobacter baumannii type VI secretion system bifunctional peptidoglycan hydrolase by Valeriya Bezkorovayna, Brooke K. Hayes, Francesca N. Gillett, Amy Wright, David I. Roper, Marina Harper, Sheena McGowan, John D. Boyce

    Published 2025-02-01
    “…The increasing development of antibiotic resistance in this organism is a global health concern. The A. baumannii clinical isolate AB307-0294 produces a type VI secretion system (T6SS) that delivers three antibacterial effector proteins that give this strain a competitive advantage against other bacteria in polymicrobial environments. …”
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  7. 16687
  8. 16688
  9. 16689

    Longitudinal DNA methylation profiles in saliva of offspring from mothers with gestational diabetes: associations with early childhood growth patterns by Teresa M. Linares-Pineda, Alfonso Lendínez-Jurado, Alberto Piserra-López, María Suárez-Arana, María Pozo, María Molina-Vega, María José Picón-César, Sonsoles Morcillo

    Published 2025-01-01
    “…Abstract Background The prevalence of obesity and type 2 diabetes mellitus (T2DM) is rising globally, particularly among children exposed to adverse intrauterine environments, such as those associated with gestational diabetes mellitus (GDM). …”
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  10. 16690

    Impacts of Recent Climate Trends and Human Activity on the Land Cover Change of the Abbay River Basin in Ethiopia by Asaminew Abiyu Cherinet, Denghua Yan, Hao Wang, Xinshan Song, Tianlin Qin, Mulualem T. Kassa, Abel Girma, Batsuren Dorjsuren, Mohammed Gedefaw, Hejia Wang, Otgonbayar Yadamjav

    Published 2019-01-01
    “…The changes in land cover were mostly caused by global and local climate influence which mainly affects the hydroclimate and eco-hydrology systems of the basin. …”
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  11. 16691

    Age-related differences in long-term potentiation-like plasticity and short-latency afferent inhibition and their association with cognitive function by Tong Wang, Ying Shen, Tianjiao Zhang, Chuan He, Qian Lu, Jie Song, Manyu Dong, Yilun Qian, Sisi Huang, Jing Teng

    Published 2024-02-01
    “…Cognitive function assessments included evaluations of global cognitive function, language, memory and executive function. …”
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  12. 16692

    Dual role of ramR mutation in enhancing immune activation and elevating eravacycline resistance in Klebsiella pneumoniae by Wei Yu, Peiyao Jia, Xiaobing Chu, Shengjie Li, Xinmiao Jia, Ying Zhu, Xiaoyu Liu, Yingchun Xu, Qiwen Yang

    Published 2024-12-01
    “…Abstract The rise of Klebsiella pneumoniae resistant to last‐resort antimicrobials poses an urgent threat to global health. The ramR‐ramA regulatory system critically influences drug resistance by regulating the AcrAB‐TolC efflux pump, which also plays a crucial role in the pathogenicity of K. pneumoniae. …”
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  13. 16693

    Patterns of general and abdominal obesity and their association with hypertension control in the iranian hypertensive population: insights from a nationwide study by Fataneh Esmaeili, Keyvan Karimi, Samaneh Akbarpour, Mohammadreza Naderian, Shirin Djalalinia, Ozra Tabatabaei-Malazy, Ali Golestani, Nazila Rezaei

    Published 2025-01-01
    “…Abstract Background The coexistence of obesity and hypertension (HTN) is a global health concern due to its association with various health abnormalities. …”
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  14. 16694

    NCAPD3 promotes diffuse large B-cell lymphoma progression through modulating SIRT1 expression in an H3K9 monomethylation-dependent manner by Tiange Lu, Juan Yang, Yiqing Cai, Mengfei Ding, Zhuoya Yu, Xiaosheng Fang, Xiangxiang Zhou, Xin Wang

    Published 2025-02-01
    “…Meanwhile, the classical transcription-activated marker, H3K4 trimethylation, was found globally upregulated after NCAPD3 knockout, suggesting that NCAPD3 might participate in chromatin remodeling and transcription regulation. …”
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  15. 16695

    Rapid assessment of pre-service midwifery education in conflict settings: findings from a cross-sectional study in Nigeria and Somalia by Emilia Iwu, Shatha Elnakib, Hawa Abdullahi, Rejoice Helma Abimiku, Charity Maina, Asia Mohamed, Kazeem Olalekan Ayodeji, George Odonye, Rifkatu Sunday, Maryan Abdulkadir Ahmed, Mohamed Ahmed Omar, Abdirisak A. Dalmar, Emilie Grant, Hannah Tappis

    Published 2025-02-01
    “…This study sought to assess the extent to which midwifery pre-service education programs meet national and global standards, and to explore how conflict affects pre-service midwifery education in Yobe State Nigeria and the Benadir and Galgaduud regions of Somalia. …”
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  16. 16696

    Large-scale evidence generation and evaluation across a network of databases for type 2 diabetes mellitus (LEGEND-T2DM): a protocol for a series of multinational, real-world compar... by Rohan Khera, Yuan Lu, Harlan M Krumholz, Martijn J Schuemie, Ruijun Chen, George Hripcsak, Marc A Suchard, Patrick B Ryan, Anna Ostropolets

    Published 2022-06-01
    “…LEGEND-T2DM will leverage the Observational Health Data Sciences and Informatics (OHDSI) community that provides access to a global network of administrative claims and electronic health record data sources, representing 190 million patients in the USA and about 50 million internationally. …”
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  17. 16697

    Low albumin-to-creatinine ratios (ACR) are associated with poor outcomes in cancer patients by Hong Zhao, Xiangrui Li, Xiaoyue Liu, Chenan Liu, Xin Zheng, Yue Chen, Jinyu Shi, Qiteng Liu, Zhaoting Bu, Hanping Shi

    Published 2025-01-01
    “…Multivariable logistic regression assessed associations between ACR and Patient—Generated Subjective Global Assessment (PG-SGA), Length of Stay (LOS), and Karnofsky Performance Status (KPS). …”
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  18. 16698

    Polybrominated Dibenzo-p-dioxins/Furans (PBDD/Fs) and Diphenyl Ethers (PBDEs) in the Indoor and Outdoor of Gymnasiums by Ching-Kai Su, Jian-He Lu, How-Ran Chao, Wei-Hsiang Chang, Ming-Hsien Tsai, Chih-Lung Wang, I-Cheng Lu, Yu-Ting Chang, Hsiao-Chi Chuang, Wan-Nurdiyana-Wan Mansor, Yi-Chyun Hsu, Ying-I Tsai, Shang-Ming Ma

    Published 2022-08-01
    “…The PBDEs levels observed in this study were relatively lower when compared with the current global data of PM2.5 and indoor dust levels of PBDEs. …”
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  19. 16699

    Coccidia Species and Geographical Distribution in Genus <i>Sus:</i> A Scoping Review by Hongyu Han, Hui Dong, Qiping Zhao, Shunhai Zhu, Bing Huang

    Published 2024-12-01
    “…Coccidiosis is a common cause of diarrhea in suckling piglets worldwide that directly reduces piglets’ immunity and increases the risk of infection with other enteropathogens, leading to increased clinical infection and mortality and consequent economic losses in the global pig industry. We searched the available literature to date, including English and Chinese articles, using six electronic bibliographic databases, including PubMed, ScienceDirect, Web of Science, CNKI, VIP Chinese Journal Database, and Wanfang Data. …”
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  20. 16700

    The Role of Autophagy in Copper-Induced Apoptosis and Developmental Neurotoxicity in SH-SY5Y Cells by Lu Lu, Ying Zhang, Wei Shi, Qian Zhou, Zhuoqi Lai, Yuepu Pu, Lihong Yin

    Published 2025-01-01
    “…Copper (Cu) is a global environmental pollutant that poses a serious threat to humans and ecosystems. …”
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