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16681
Electrocardiographic signs of cardiac ischemia at rest and during exercise in patients with COPD traveling to 3,100 m: data from a randomized trial of acetazolamide
Published 2025-02-01“…We assessed electrocardiogram (ECG)-derived signs of cardiac ischemia and the effects of preventive acetazolamide therapy in COPD patients traveling to high altitudes.MethodsPatients with COPD [Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) grades 2–3] and a predicted forced expiratory volume in 1 s (FEV1) of 66 ± 11% (mean ± SD), aged 57 ± 8 years, and living <1,000 m were included in this analysis of secondary outcomes from a randomized placebo-controlled double-blind trial (www.clinicaltrials.gov, NCT03156231). …”
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16682
Evaluating the effectiveness of handheld ultrasound in primary blast lung injury: a comprehensive study
Published 2025-01-01“…Abstract The incidence of blast injuries has been rising globally, particularly affecting the lungs due to their vulnerability. …”
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16683
Comprehensive analysis of antimicrobial resistance dynamics among broiler and duck intensive production systems
Published 2025-02-01“…Abstract Antimicrobial resistance (AMR) is a global health challenge requiring cross-sector action, with research largely focused on chickens, leaving ducks underexplored. …”
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16684
Correlation analysis of the impact of Clonorchis sinensis juvenile on gut microbiota and transcriptome in mice
Published 2025-02-01“…ABSTRACT Clonorchiasis remains a non-negligible global zoonosis, imposing serious socio-economic burdens in endemic regions. …”
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16685
Ligilactobacillus salivarius LZZAY01 accelerated autophagy and apoptosis in colon cancer cells and improved gut microbiota in CAC mice
Published 2025-02-01“…ABSTRACT Colorectal cancer (CRC) is one of the malignant tumors globally, with high morbidity and mortality rates. …”
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16686
Delivery determinants of an Acinetobacter baumannii type VI secretion system bifunctional peptidoglycan hydrolase
Published 2025-02-01“…The increasing development of antibiotic resistance in this organism is a global health concern. The A. baumannii clinical isolate AB307-0294 produces a type VI secretion system (T6SS) that delivers three antibacterial effector proteins that give this strain a competitive advantage against other bacteria in polymicrobial environments. …”
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16687
Temporal trends, associated risk factors and longitudinal cardiovascular outcomes of body roundness among middle-aged and older Chinese adults: from the China Health and Retirement...
Published 2025-01-01“…BackgroundObesity is a major global health issue, driving high morbidity and mortality rates. …”
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16688
A systematic review and meta-analysis of the impact of transcranial direct current stimulation on cognitive function in older adults with cognitive impairments: the influence of do...
Published 2025-02-01“…Conclusion tDCS demonstrated efficacy in enhancing global cognition in older people with cognitive impairments, providing insight into optimal parameters for clinical application. …”
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16689
Longitudinal DNA methylation profiles in saliva of offspring from mothers with gestational diabetes: associations with early childhood growth patterns
Published 2025-01-01“…Abstract Background The prevalence of obesity and type 2 diabetes mellitus (T2DM) is rising globally, particularly among children exposed to adverse intrauterine environments, such as those associated with gestational diabetes mellitus (GDM). …”
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16690
Impacts of Recent Climate Trends and Human Activity on the Land Cover Change of the Abbay River Basin in Ethiopia
Published 2019-01-01“…The changes in land cover were mostly caused by global and local climate influence which mainly affects the hydroclimate and eco-hydrology systems of the basin. …”
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16691
Age-related differences in long-term potentiation-like plasticity and short-latency afferent inhibition and their association with cognitive function
Published 2024-02-01“…Cognitive function assessments included evaluations of global cognitive function, language, memory and executive function. …”
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16692
Dual role of ramR mutation in enhancing immune activation and elevating eravacycline resistance in Klebsiella pneumoniae
Published 2024-12-01“…Abstract The rise of Klebsiella pneumoniae resistant to last‐resort antimicrobials poses an urgent threat to global health. The ramR‐ramA regulatory system critically influences drug resistance by regulating the AcrAB‐TolC efflux pump, which also plays a crucial role in the pathogenicity of K. pneumoniae. …”
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16693
Patterns of general and abdominal obesity and their association with hypertension control in the iranian hypertensive population: insights from a nationwide study
Published 2025-01-01“…Abstract Background The coexistence of obesity and hypertension (HTN) is a global health concern due to its association with various health abnormalities. …”
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16694
NCAPD3 promotes diffuse large B-cell lymphoma progression through modulating SIRT1 expression in an H3K9 monomethylation-dependent manner
Published 2025-02-01“…Meanwhile, the classical transcription-activated marker, H3K4 trimethylation, was found globally upregulated after NCAPD3 knockout, suggesting that NCAPD3 might participate in chromatin remodeling and transcription regulation. …”
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16695
Rapid assessment of pre-service midwifery education in conflict settings: findings from a cross-sectional study in Nigeria and Somalia
Published 2025-02-01“…This study sought to assess the extent to which midwifery pre-service education programs meet national and global standards, and to explore how conflict affects pre-service midwifery education in Yobe State Nigeria and the Benadir and Galgaduud regions of Somalia. …”
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16696
Large-scale evidence generation and evaluation across a network of databases for type 2 diabetes mellitus (LEGEND-T2DM): a protocol for a series of multinational, real-world compar...
Published 2022-06-01“…LEGEND-T2DM will leverage the Observational Health Data Sciences and Informatics (OHDSI) community that provides access to a global network of administrative claims and electronic health record data sources, representing 190 million patients in the USA and about 50 million internationally. …”
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16697
Low albumin-to-creatinine ratios (ACR) are associated with poor outcomes in cancer patients
Published 2025-01-01“…Multivariable logistic regression assessed associations between ACR and Patient—Generated Subjective Global Assessment (PG-SGA), Length of Stay (LOS), and Karnofsky Performance Status (KPS). …”
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16698
Polybrominated Dibenzo-p-dioxins/Furans (PBDD/Fs) and Diphenyl Ethers (PBDEs) in the Indoor and Outdoor of Gymnasiums
Published 2022-08-01“…The PBDEs levels observed in this study were relatively lower when compared with the current global data of PM2.5 and indoor dust levels of PBDEs. …”
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16699
Coccidia Species and Geographical Distribution in Genus <i>Sus:</i> A Scoping Review
Published 2024-12-01“…Coccidiosis is a common cause of diarrhea in suckling piglets worldwide that directly reduces piglets’ immunity and increases the risk of infection with other enteropathogens, leading to increased clinical infection and mortality and consequent economic losses in the global pig industry. We searched the available literature to date, including English and Chinese articles, using six electronic bibliographic databases, including PubMed, ScienceDirect, Web of Science, CNKI, VIP Chinese Journal Database, and Wanfang Data. …”
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16700
The Role of Autophagy in Copper-Induced Apoptosis and Developmental Neurotoxicity in SH-SY5Y Cells
Published 2025-01-01“…Copper (Cu) is a global environmental pollutant that poses a serious threat to humans and ecosystems. …”
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